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8 p, 799.5 KB |
Periaqueductal gray matter echogenicity as a marker of migraine chronification : a case control study
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Vilas, Dolores (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rubio, Sara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gea, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ríos, José (Universitat Autònoma de Barcelona) ;
Ispierto, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Paré-Curell, Martí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Millán, Mònica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dorado Bouix, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Migraine is one of the most prevalent and disabling medical diseases in the world. The periaqueductal gray matter and the red nucleus play an important role in its pathogenesis. Our aim was to evaluate the echogenicity of the periaqueductal gray matter and the red nucleus in patients with migraine, by means of transcranial ultrasound. [...]
2023 -  10.1186/s10194-023-01576-3
Journal of headache and pain, Vol. 24 (april 2023)
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16 p, 7.7 MB |
Establishment of a reproducible and minimally invasive ischemic stroke model in swine
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Castaño, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Melià Sorolla, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García Serran, Alexia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
De Gregorio-Rocasolano, Nuria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García-Sort, Maria Rosa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Valls-Carbó, Adrián (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pino, Osvaldo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Grífols, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Iruela-Sánchez, Alba (Canon Medical Systems) ;
Palomar-García, Alicia (Canon Medical Systems) ;
Puig, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martí-Sistac, Octavi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gasull Dalmau, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
The need for advances in the management/treatment options for ischemic stroke patients requires that upcoming preclinical research uses animals with more human-like brain characteristics. The porcine brain is considered appropriate, although the presence of the rete mirabile (RM) prevents direct catheterization of the intracranial arteries to produce focal cerebral ischemia. [...]
2023 - 10.1172/jci.insight.163398
JCI Insight, Vol. 8 (april 2023)
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11 p, 946.8 KB |
APRIL : A double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke
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Hernández-Jiménez, Macarena (AptaTargets (Madrid)) ;
Abad-Santos, Francisco (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Cotgreave, Ian (Research Institutes of Sweden) ;
Gallego, Jaime (Neurological Center of Navarra) ;
Jilma, Bernd (Medical University of Vienna) ;
Flores, Alan (Hospital Universitari Joan XXIII de Tarragona) ;
Jovin, Tudor G. (Cooper Neurological Institute) ;
Vivancos, José (Hospital Universitario de la Princesa (Madrid)) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montaner, Joan (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Casariego, Joaquín (Aldebaran Health Intelligence (Madrid)) ;
Dalsgaard, Mads (Cureteq AG) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Liebeskind, David S. (UCLA Stroke Center) ;
Cobo, Erik (Universitat Politècnica de Catalunya. BarcelonaTech) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
In the reperfusion era, a new paradigm of treating patients with endovascular treatment (EVT) and neuroprotective drugs is emerging as a promising therapeutic option for patients with acute ischemic stroke (AIS). [...]
2023 - 10.3389/fneur.2023.1127585
Frontiers in neurology, Vol. 14 (february 2023)
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13 p, 254.3 KB |
Long-term antibiotic therapy in patients with surgery-indicated not undergoing surgery infective endocarditis
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Vallejo Camazon, Nuria (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Mateu, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Escolà-Vergé, Laura (Hospital Universitari Vall d'Hebron) ;
Fernández-Hidalgo, Nuria (Hospital Universitari Vall d'Hebron) ;
Gurguí, Mercè (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Pérez Rodriguez, María Teresa (Unidad de Enfermedades Infecciosas. Servicio de Medicina Interna. Complexo Hospitalario de Vigo) ;
Cuervo, Guillermo (Hospital Universitari de Bellvitge) ;
Núñez Aragón, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Llibre, Cinta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sopena, Nieves (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quesada, María Dolores (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Berastegui García, Elisabet (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teis, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
López Ayerbe, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Juncà Puig, Gladys (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gual, Francisoc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ferrer Sistach, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vivero, Ainhoa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Reynaga, Esteban (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muñoz Guijosa, Christian (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pedro-Botet, Lluïsa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Universitat Autònoma de Barcelona
Background: To date, there is little information regarding management of patients with infective endocarditis (IE) that did not undergo an indicated surgery. Therefore, we aimed to evaluate prognosis of these patients treated with a long-term antibiotic treatment strategy, including oral long term suppressive antibiotic treatment in five referral centres with a multidisciplinary endocarditis team. [...]
2021 - 10.5603/CJ.a2021.0054
Cardiology Journal, Vol. 28 Núm. 4 (2021) , p. 566-578
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8 p, 731.6 KB |
COVID-19's impact on care practice for alpha-1-antitrypsin deficiency patients
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Calle Rubio, Myriam (Universidad Complutense de Madrid) ;
López-Campos, José Luis (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Michel de la Rosa, Francisco Javier (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Hernández Pérez, José María (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Montero Martínez, Carmen (Complejo Hospitalario Universitario de A Coruña) ;
Montoro Ronsano, José Bruno (Hospital Universitari Vall d'Hebron) ;
Casas-Maldonado, Francisco (Universidad de Granada) ;
Rodríguez Hermosa, Juan Luis (Universidad Complutense de Madrid) ;
Tabernero Huguet, Eva María (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Martínez Sesmero, José Manuel (Hospital Clínico San Carlos (Madrid)) ;
Martínez Rivera, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Callejas González, Francisco Javier (Hospital Complejo Universitario de Albacete) ;
Torres Durán, María (Hospital Álvaro Cunqueiro (Vigo)) ;
Universitat Autònoma de Barcelona
Patients with alpha-1 antitrypsin deficiency (AATD), commonly categorized as a rare disease, have been affected by the changes in healthcare management brought about by COVID-19. This study's aim was to identify the changes that have taken place in AATD patient care as a result of the COVID-19 pandemic in Spain and to propose experts' recommendations aimed at ensuring humanized and quality care for people with AATD in the post-pandemic situation. [...]
2023 - 10.1186/s12913-023-09094-3
BMC health services research, Vol. 23 (january 2023)
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11 p, 623.7 KB |
Stroke etiologies in patients with COVID-19 : the SVIN COVID-19 multinational registry
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Ramos-Araque, María E. (Hospital Clínico Universitario de Valladolid) ;
Siegler, James E. (Cooper University Hospital. Cooper Neurologic Institute) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Requena, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
López, Cristina (Hospital Clínico Universitario de Valladolid) ;
De Lera Alfonso, Mercedes (Hospital Clínico Universitario de Valladolid) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Hernández Pérez, Isabel (Hospital Clínico Universitario de Valladolid) ;
Gómez-Vicente, Beatriz (Hospital Clínico Universitario de Valladolid) ;
Talavera, Blanca (Hospital Clínico Universitario de Valladolid) ;
Portela, Pere Cardona (Hospital Universitari de Bellvitge) ;
Guillen, Ana Nuñez (Hospital Universitari de Bellvitge) ;
Urra, Xabier (Hospital Clínic i Provincial de Barcelona) ;
Llull, Laura (Hospital Clínic i Provincial de Barcelona) ;
Renú, Arturo (Hospital Clínic i Provincial de Barcelona) ;
Nguyen, Thanh N. (Boston University School of Medicin) ;
Jillella, Dinesh (Emory University School of Medicine) ;
Nahab, Fadi (Emory University School of Medicine) ;
Nogueira, Raul (Grady Memorial Hospital) ;
Haussen, Diogo (Grady Memorial Hospital) ;
Then, Ryna (Cooper University Hospital) ;
Thon, Jesse M. (Cooper University Hospital) ;
Esparragoza, Luis Rodríguez (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bustamante, Alejandro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mansour, Ossama Yassin ;
Megahed, Mohammed (Alexandria University) ;
Hassan, Tamer (Alexandria University) ;
Liebeskind, David S. (Ronald Reagan UCLA Medical Center) ;
Hassan, Ameer E (University of Texas Rio Grande Valley) ;
Bushnaq, Saif (Bon Secours Mercy Health St. Vincent Hospital, Toledo, OH USA) ;
Osman, Mohamed (Bon Secours Mercy Health St. Vincent Hospital, Toledo, OH USA) ;
Vazquez, Alejandro Rodriguez (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Coronavirus disease 2019 (COVID-19) is associated with a small but clinically significant risk of stroke, the cause of which is frequently cryptogenic. In a large multinational cohort of consecutive COVID-19 patients with stroke, we evaluated clinical predictors of cryptogenic stroke, short-term functional outcomes and in-hospital mortality among patients according to stroke etiology. [...]
2021 - 10.1186/s12883-021-02075-1
BMC Neurology, Vol. 21 (january 2021)
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8 p, 476.6 KB |
Blood Biomarker Panels for the Early Prediction of Stroke-Associated Complications
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Faura, Júlia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bustamante, Alejandro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Reverté, Silvia (Hospital de Tortosa Verge de la Cinta) ;
García-Berrocoso, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Millán, Mónica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Castellanos, Mar (Instituto de Investigación Biomédica de A Coruña) ;
Lara-Rodríguez, Blanca (Hospital Universitari de Bellvitge) ;
Zaragoza, Josep (Hospital de Tortosa Verge de la Cinta) ;
Ventura, Oriol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
van Eendenburg, Cecile (Hospital Universitari de Girona Doctor Josep Trueta) ;
Cardona, Pere-Joan (Hospital Universitari de Bellvitge) ;
López-Cancio, Elena (Hospital Universitario Central de Asturias) ;
Cánovas, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Serena, Joaquín (Hospital Universitari de Girona Doctor Josep Trueta) ;
Rubiera del Fueyo, Marta A. (Hospital Universitari Vall d'Hebron) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Acute decompensated heart failure (ADHF) and respiratory tract infections (RTIs) are potentially life-threatening complications in patients experiencing stroke during hospitalization. We aimed to test whether blood biomarker panels might predict these complications early after admission. [...]
2021 - 10.1161/JAHA.120.018946
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 10 (february 2021)
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11 p, 1.2 MB |
Blood Biomarkers to Predict Long-Term Mortality after Ischemic Stroke
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Ramiro, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Abraira del Fresno, Laura (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Quintana, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
García-Rodríguez, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Santamarina, Estevo (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Álvarez Sabín, José (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Zaragoza, Josep (Hospital de Tortosa Verge de la Cinta) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ustrell, Xavier (Hospital Universitari Joan XXIII de Tarragona) ;
Lara-Rodríguez, Blanca (Hospital Universitari de Bellvitge) ;
Terceño, Mikel (Hospital Universitari de Girona Doctor Josep Trueta) ;
Bustamante, Alejandro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Stroke is a major cause of disability and death globally, and prediction of mortality represents a crucial challenge. We aimed to identify blood biomarkers measured during acute ischemic stroke that could predict long-term mortality. [...]
2021 - 10.3390/life11020135
Life, Vol. 11 (february 2021)
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14 p, 573.4 KB |
Effects and Mechanisms of Cognitive, Aerobic Exercise, and Combined Training on Cognition, Health, and Brain Outcomes in Physically Inactive Older Adults : The Projecte Moviment Protocol
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Castells-Sánchez, Alba (Institut de Recerca Sant Joan de Déu) ;
Roig-Coll, Francesca (Universitat de Barcelona. Departament de Psiquiatria i de Psicobiologia Clínica) ;
Lamonja-Vicente, Noemí (Institut de Recerca Sant Joan de Déu) ;
Altés-Magret, M. (Universitat de Barcelona. Departament de Psiquiatria i de Psicobiologia Clínica) ;
Torán Montserrat, Pere (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Via, M. (Institut de Recerca Sant Joan de Déu) ;
García-Molina, Alberto (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, Jose M. (Institut Germans Trias i Pujol. Institut Guttmann) ;
Heras, Antonio (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Alzamora, M. Teresa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Forés Raurell, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Pera, Guillem (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Dacosta Aguayo, Rosalia (Universitat de Barcelona. Departament de Psiquiatria i de Psicobiologia Clínica) ;
Soriano-Raya, J. J. (Universitat de Barcelona. Institut de Neurociències) ;
Cáceres, Cynthia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montero-Alía, Pilar (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Montero-Alía, Juan José (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Jimenez-Gonzalez, M. M. (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Perera Lluna, Alexandre (Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial) ;
Grove, G. A. (Department of Psychology. University of Pittsburgh) ;
Munuera, Josep (Hospital Sant Joan de Déu (Manresa)) ;
Domènech, S. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Erickson, K. I. (Department of Psychology. University of Pittsburgh) ;
Mataró, M. (Institut de Recerca Sant Joan de Déu) ;
Universitat Autònoma de Barcelona
Introduction: Age-related health, brain, and cognitive impairment is a great challenge in current society. Cognitive training, aerobic exercise and their combination have been shown to benefit health, brain, cognition and psychological status in healthy older adults. [...]
2019 - 10.3389/fnagi.2019.00216
Frontiers in aging neuroscience, Vol. 11 (14 2019) , p. 216
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12 p, 2.7 MB |
High-permeability region size on perfusion CT predicts hemorrhagic transformation after intravenous thrombolysis in stroke
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Puig, Josep (Institut d'Investigació Biomèdica de Girona) ;
Blasco, Gerard (Institut d'Investigació Biomèdica de Girona) ;
Daunis-i-Estadella, Pepus (Universitat de Girona. Departament d'Informàtica, Matemàtica Aplicada i Estadística) ;
Eendendburg, Cecile van (Institut d'Investigació Biomèdica de Girona) ;
Carrillo-García, María (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Aboud, Carlos (Hospital Universitari i Politècnic La Fe de València) ;
Hernández-Pérez, María ;
Serena, Joaquín (Institut d'Investigació Biomèdica de Girona) ;
Biarnés, Carles (Institut d'Investigació Biomèdica de Girona) ;
Nael, Kambiz (ICAHN School of Medicine at Mount Sinai) ;
Liebeskind, David S. (Neurovascular Imaging Research Core and UCLA Stroke Center) ;
Thomalla, Götz (Department of Neurology, University Medical Centre Hamburg-Eppendorf) ;
Menon, Bijoy K. (Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary) ;
Demchuk, Andrew (Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary) ;
Wintermark, Max (Department of Radiology, Neuroradiology Division, Stanford University, Palo Alto, California) ;
Pedraza, Salvador (Institut d'Investigació Biomèdica de Girona) ;
Castellanos, Mar (Instituto de Investigación Biomédica de A Coruña)
Objective. Blood-brain barrier (BBB) permeability has been proposed as a predictor of hemorrhagic transformation (HT) after tissue plasminogen activator (tPA) administration; however, the reliability of perfusion computed tomography (PCT) permeability imaging for predicting HT is uncertain. [...]
2017 - 10.1371/journal.pone.0188238
PloS one, Vol. 12 Núm. 11 (november 2017) , p. 1-12
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