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Resultats globals: 5 registres trobats en 0.02 segons.
Articles, 5 registres trobats
Articles 5 registres trobats  
1.
15 p, 2.2 MB Recovering What Matters : High Protein Recovery after Endotoxin Removal from LPS-Contaminated Formulations Using Novel Anti-Lipid A Antibody Microparticle Conjugates / Casonato Melo, Cristiane (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ; Fux, Alexandra C. (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ; Himly, Martin (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ; Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ; Schlahsa, Laura (Miltenyi Biotec B.V. & Co) ; Siewert, Christiane (Miltenyi Biotec B.V. & Co) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Duschl, Albert (Paris Lodron University of Salzburg. Department of Biosciences & Medical Biology) ; Gessner, Isabel (Miltenyi Biotec B.V. & Co) ; Fauerbach, Jonathan A. (Miltenyi Biotec B.V. & Co)
Endotoxins or lipopolysaccharides (LPS), found in the outer membrane of Gram-negative bacterial cell walls, can stimulate the human innate immune system, leading to life-threatening symptoms. Therefore, regulatory limits for endotoxin content apply to injectable pharmaceuticals, and excess LPS must be removed before commercialization. [...]
2023 - 10.3390/ijms241813971
International journal of molecular sciences, Vol. 24, Issue 18 (September 2023) , art. 13971  
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2.
18 p, 2.1 MB The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types / Schlinkert, Paul (Paris Lodron-University of Salzburg. Department of Molecular Biology) ; Casals, Eudald (Institut Català de Nanociència i Nanotecnologia) ; Boyles, Matthew S. P. (Paris Lodron-University of Salzburg. Department of Molecular Biology) ; Tischler, Ulrike (Paris Lodron-University of Salzburg. Department of Molecular Biology) ; Hornig, Eva (Paris Lodron-University of Salzburg. Department of Molecular Biology) ; Tran Thi Thanh, Ngoc (Institut Català de Nanociència i Nanotecnologia) ; Zhao, Jiayuan (Institute for Work and Health) ; Himly, Martin (Paris Lodron-University of Salzburg. Department of Molecular Biology) ; Riediker, Michael (Institue for Occupational Medicine) ; Oostingh, G. J. (Salzburg University of Applied Sciences) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Duschl, Albert (Paris Lodron-University of Salzburg. Department of Molecular Biology)
Background: Nanoparticle (NPs) functionalization has been shown to affect their cellular toxicity. To study this, differently functionalized silver (Ag) and gold (Au) NPs were synthesised, characterised and tested using lung epithelial cell systems. [...]
2015 - 10.1186/s12951-014-0062-4
Journal of nanobiotechnology, Vol. 13 (January 2015) , art. 1  
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3.
20 p, 3.7 MB Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation / Li, Yang (Hebei Normal University) ; Shi, Zhenzhen (Kansas State University. Department of Anatomy and Physiology) ; Radauer-Preiml, Isabella (University of Salzburg. Department of Molecular Biology) ; Andosch, Ancuela (University of Salzburg. Department of Molecular Biology) ; Casals, Eudald (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Luetz-Meindl, Ursula (University of Salzburg. Department of Molecular Biology) ; Cobaleda-Siles, Macarena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lin, Zhoumeng (Kansas State University. Department of Anatomy and Physiology) ; Jaberi-Douraki, Majid (Kansas State University. Department of Anatomy and Physiology) ; Italiani, Paola (National Research Council) ; Horejs-Hoeck, Jutta (University of Salzburg. Department of Molecular Biology) ; Himly, Martin (University of Salzburg. Department of Molecular Biology) ; Monteiro-Riviere, Nancy A. (Kansas State University. Department of Anatomy and Physiology) ; Duschl, Albert (University of Salzburg. Department of Molecular Biology) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Boraschi, Diana (National Research Council)
Nanoparticles (NPs) are easily contaminated by bacterial endotoxin (lipopolysaccharide [LPS]). The presence of LPS can be responsible for many immune/inflammatory effects attributed to NPs. In this study, we examined the effects of LPS adsorption on the NP surface on the formation of a biocorona in biological fluids and on the subsequent inflammation-inducing activity of NPs. [...]
2017 - 10.1080/17435390.2017.1401142
Nanotoxicology, Vol. 11, Issue 9-10 (December 2017) , p. 1157-1175  
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4.
20 p, 1.9 MB Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components / Boyles, Matthew S. P. (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Kristl, Theresa (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Andosch, Ancuela (Paris-Lodron-Universität Salzburg. Department of Cell Biology) ; Zimmermann, Mirjam (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Tran Thi Thanh, Ngoc (Institut Català de Nanociència i Nanotecnologia) ; Casals, Eudald (Institut Català de Nanociència i Nanotecnologia) ; Himly, Martin (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Puntes, Víctor (Institució Catalana de Recerca i Estudis Avançats) ; Huber, Christian G. (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Lütz-Meindl, Ursula (Paris-Lodron-Universität Salzburg. Department of Cell Biology) ; Duschl, Albert (Paris-Lodron-Universität Salzburg. Department of Molecular Biology)
Gold nanoparticles (AuNPs) are a popular choice for use in medical and biomedical research applications. With suitable functionalisation AuNPs can be applied in drug delivery systems, or can aid in disease diagnosis. [...]
2015 - 10.1186/s12951-015-0146-9
Journal of nanobiotechnology, Vol. 13, Issue 84 (november 2015)  
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5.
12 p, 1.1 MB Assessment of a panel of interleukin-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure under different cell culture conditions / Stoehr, Linda C. (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Endes, Carola (Universität Freiburg. BioNanomaterials, Adolphe Merkle Institute) ; Radauer-Preiml, Isabella (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Boyles, Matthew S. P. (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Casals, Eudald (Institut Català de Nanociència i Nanotecnologia) ; Balog, Sandor (Universität Freiburg. Soft Matter Scattering) ; Pesch, Markus (Grimm Aerosol Technik GmbH & Co. KG, Ainring) ; Petri-Fink, Alke (Universität Freiburg. BioNanomaterials, Adolphe Merkle Institute) ; Rothen-Rutishauser, Barbara (Universität Freiburg. BioNanomaterials, Adolphe Merkle Institute) ; Himly, Martin (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Clift, Martin J. D. (Universität Freiburg. BioNanomaterials, Adolphe Merkle Institute) ; Duschl, Albert (Paris-Lodron-Universität Salzburg. Department of Molecular Biology)
Stably transfected lung epithelial reporter cell lines pose an advantageous alternative to replace complex experimental techniques to monitor the pro-inflammatory response following nanoparticle (NP) exposure. [...]
2015 - 10.1186/s12989-015-0104-6
Particle and fibre toxicology, Vol. 12 (September 2015) , art. 29  
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