Results overview: Found 2 records in 0.02 seconds.
Articles, 2 records found
Articles 2 records found  
1.
11 p, 1.4 MB Hepatic Lactate Dehydrogenase A : An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria / Ariceta Iraola, Gema (Hospital Universitari Vall d'Hebron) ; Barrios, Kelly (Dicerna Pharmaceuticals, Inc., Lexington) ; Brown, Bob D. (Dicerna Pharmaceuticals, Inc., Lexington) ; Hoppe, Bernd (German Hyperoxaluria Center Cologne/Bonn) ; Rosskamp, Ralf (Dicerna Pharmaceuticals, Inc., Lexington) ; Langman, Craig B. (Ann and Robert H. Lurie Children's Hospital of Chicago) ; Universitat Autònoma de Barcelona
Primary hyperoxaluria (PH) is a family of 3 rare genetic disorders of hepatic glyoxylate metabolism that lead to overproduction and increased renal excretion of oxalate resulting in progressive renal damage. [...]
2021 - 10.1016/j.ekir.2021.01.029
Kidney International Reports, Vol. 6 (february 2021) , p. 1088-1098  
2.
12 p, 1.5 MB Efficacy and safety of paricalcitol in children with stages 3 to 5 chronic kidney disease / Webb, Nicholas J. A. (Royal Manchester Children's Hospital, Manchester, UK) ; Lerner, Gary (Keck School of Medicine-Children's Hospital Los Angeles, USA) ; Warady, Bradley A. (Children's Mercy Hospital, Kansas City, USA.) ; Dell, Katherine M. (Cleveland Clinic Children's, USA) ; Greenbaum, Larry A. (Emory School of Medicine and Children's Healthcare of Atlanta, USA.) ; Ariceta Iraola, Gema (Hospital Universitari Vall d'Hebron) ; Hoppe, Bernd (University Hospital Bonn (Bonn, Alemanya)) ; Linde, Peter (AbbVie Inc., North Chicago, USA) ; Lee, Ho-Jin (AbbVie Inc., North Chicago, USA) ; Eldred, Ann (AbbVie Inc., North Chicago, USA) ; Dufek, Matthew B. (AbbVie Inc., North Chicago, USA) ; Universitat Autònoma de Barcelona
Elevated intact parathyroid hormone (iPTH) levels can contribute to morbidity and mortality in children with chronic kidney disease (CKD). We evaluated the pharmacokinetics, efficacy, and safety of oral paricalcitol in reducing iPTH levels in children with stages 3-5 CKD. [...]
2017 - 10.1007/s00467-017-3579-6
Pediatric Nephrology, Vol. 32 (march 2017) , p. 1221-1232  

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