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17 p, 2.6 MB DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial / Davis Armstrong, N.M. (East Carolina University. Department of Biology) ; Chen, Wei-Min (University of Virginia. Department of Public Health Sciences) ; Hsu, F.C. (Wake Forest School of Medicine) ; Brewer, M.S. (East Carolina University. Department of Biology) ; Cullell, Natalia (Fundació per la Recerca Biomèdica i Social Mútua de Terrassa) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Williams, S.R. (University of Virginia. Department of Neurology) ; Sale, M.M. (University of Virginia. Department of Public Health Sciences) ; Worrall, B.B. (University of Virginia. Department of Neurology) ; Keene, K.L. (East Carolina University. Brody School of Medicine)
Aberrant DNA methylation profiles have been implicated in numerous cardiovascular diseases; however, few studies have investigated how these epigenetic modifications contribute to stroke recurrence. The aim of this study was to identify methylation loci associated with the time to recurrent cerebro- and cardiovascular events in individuals of European and African descent. [...]
2021 - 10.1371/journal.pone.0254562
PloS one, Vol. 16 Núm. 7 July (july 2021) , p. e0254562  

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