Results overview: Found 14 records in 0.01 seconds.
Articles, 13 records found
Research literature, 1 records found
Articles 13 records found  1 - 10next  jump to record:
1.
10 p, 766.1 KB One-step immobilization of antibodies and DNA on gold sensor surfaces via a poly-adenine oligonucleotide approach / Huertas, César S. (Institut Català de Nanociència i Nanotecnologia) ; Soler Aznar, Maria (Institut Català de Nanociència i Nanotecnologia) ; Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Label-free plasmonic biosensors have demonstrated promising capabilities as analytical tools for the detection of virtually any type of biomarker. They are presented as good candidates for precision diagnostics since they offer highly sensitive, cost-effective solutions that can be used in any clinical or laboratory setting without the need for specialized trainees. [...]
2020 - 10.1021/acs.analchem.0c02619
Analytical chemistry, Vol. 92, issue 18 (Sep. 2020) , p. 12596-12604  
2.
18 p, 3.3 MB Fast and accurate pneumocystis pneumonia diagnosis in human samples using a label-free plasmonic biosensor / Calvo Lozano, Olalla (Institut Català de Nanociència i Nanotecnologia) ; Aviñó, Ana (Institut de Química Avançada de Catalunya) ; Friaza, Vicente (Instituto de Biomedicina de Sevilla) ; Medina Escuela, Alfonso (Universidad de Las Palmas de Gran Canaria. Instituto Universitario de Microelectrónica Aplicada) ; Huertas, César S. (Institut Català de Nanociència i Nanotecnologia) ; Calderón, Enrique J. (Universidad de Sevilla. Departamento de Medicina) ; Eritja, Ramon (Institut de Química Avançada de Catalunya) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Pneumocystis jirovecii is a fungus responsible for human Pneumocystis pneumonia, one of the most severe infections encountered in immunodepressed individuals. The diagnosis of Pneumocystis pneumonia continues to be challenging due to the absence of specific symptoms in infected patients. [...]
2020 - 10.3390/NANO10061246
Nanomaterials, Vol. 10, issue 6 (June 2020) , art. 1246  
3.
12 p, 1.0 MB Site-Specific mRNA Cleavage for Selective and Quantitative Profiling of Alternative Splicing with Label-Free Optical Biosensors / Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Bonnal, Sophie (Universitat Pompeu Fabra) ; Soler Aznar, Maria (Institut Català de Nanociència i Nanotecnologia) ; Escuela, Alfonso M. (Universidad de Las Palmas de Gran Canaria) ; Valcárcel, Juan (Universitat Pompeu Fabra) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Alternative splicing of mRNA precursors is a key process in gene regulation, contributing to the diversity of proteomes by the alternative selection of exonic sequences. Alterations in this mechanism are associated with most cancers, enhancing their proliferation and survival, and can be employed as cancer biomarkers. [...]
2019 - 10.1021/acs.analchem.9b03898
Analytical chemistry, Vol. 91, Issue 23 (December 2019) , p. 15138-15146  
4.
25 p, 1.7 MB Advanced Evanescent-Wave Optical Biosensors for the Detection of Nucleic Acids : An Analytic Perspective / Huertas, César S (Royal Melbourne Institute of Technology University) ; Calvo Lozano, Olalla (Institut Català de Nanociència i Nanotecnologia) ; Mitchell, Arnan (Royal Melbourne Institute of Technology University) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Evanescent-wave optical biosensors have become an attractive alternative for the screening of nucleic acids in the clinical context. They possess highly sensitive transducers able to perform detection of a wide range of nucleic acid-based biomarkers without the need of any label or marker. [...]
2019 - 10.3389/fchem.2019.00724
Frontiers in chemistry, Vol. 7 (October 2019) , art. 724  
5.
53 p, 6.1 MB Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity / Aviñó, Anna (Institut de Química Avançada de Catalunya) ; Jorge, Andreia F. (Universidade de Coimbra) ; Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Cova, Tania F.G.G. (Universidade de Coimbra) ; Pais, Alberto (Universidade de Coimbra) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia) ; Eritja, Ramon (Institut de Química Avançada de Catalunya) ; Fàbrega, Carme (Institut de Química Avançada de Catalunya)
Aptamers are single-stranded RNA or DNA molecules that specifically recognize their targets and have proven valuable for functionalizing sensitive biosensors. α-thrombin is a trypsin-like serine proteinase which plays a crucial role in haemostasis and thrombosis. [...]
2019 - 10.1016/j.bbagen.2019.06.014
Biochimica et Biophysica Acta - General Subjects, Vol. 1863, Issue 10 (October 2019) , p. 1619-1630  
6.
38 p, 3.1 MB Prospects of optical biosensors for emerging label-free RNA analysis / Carrascosa, Laura G. (Institut Català de Nanociència i Nanotecnologia) ; Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
RNA is critical in countless cellular processes, and researchers are constantly discovering new types and attributing them different roles. Consequently, a growing interest in efficient RNA analysis has arisen. [...]
2016 - 10.1016/j.trac.2016.02.018
TrAC - Trends in Analytical Chemistry, Vol. 80 (June 2016) , p. 177-189  
7.
32 p, 1.1 MB Quantitative evaluation of alternatively spliced mRNA isoforms by label-free real-time plasmonic sensing / Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Carrascosa, Laura G. (Institut Català de Nanociència i Nanotecnologia) ; Bonnal, Sophie (Universitat Pompeu Fabra) ; Valcárcel, Juan (Universitat Pompeu Fabra) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Alternative splicing of mRNA precursors enables cells to generate different protein outputs from the same gene depending on their developmental or homeostatic status. Its deregulation is strongly linked to disease onset and progression. [...]
2016 - 10.1016/j.bios.2015.11.023
Biosensors and bioelectronics, Vol. 78 (April 2016) , p. 118-125  
8.
8 p, 201.2 KB Simple, low-cost and timely optical biosensors for the detection of epigenetics biomarkers : the future of cancer diagnosis / Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
The cancer burden continues to grow with enormous physical, emotional, and financial pressure on individuals, families, communities, and health systems. Early detection and effective treatment are crucial. [...]
2017
European Medical Journal Oncology, Vol. 5, Núm. 1 (October 2017) , p. 54-61  
9.
28 p, 1.0 MB Label-free DNA-methylation detection by direct ds-DNA fragment screening using poly-purine hairpins / Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Aviñó, Anna (Institut de Química Avançada de Catalunya) ; Kurachi, Cristina (Institut Català de Nanociència i Nanotecnologia) ; Piqué, Albert (Institut Català de Nanociència i Nanotecnologia) ; Sandoval, Juan (Institut de Recerca Biomèdia Bellvitge) ; Eritja, Ramon (Institut de Química Avançada de Catalunya) ; Esteller, Manel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Cancer diagnosis continuously evolves due to the better understanding of tumorigenic processes. DNA-methylation is consolidated as an effective biomarker for cancer prognosis and diagnostic even in tumors of unknown origin. [...]
2018 - 10.1016/j.bios.2018.08.027
Biosensors and bioelectronics, Vol. 120 (November 2018) , p. 47-54  
10.
25 p, 1.1 MB Label-free plasmonic biosensors for point-of-care diagnostics : a review / Soler Aznar, Maria (Institut Català de Nanociència i Nanotecnologia) ; Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Introduction: Optical biosensors, particularly those based on nanoplasmonics technology, have emerged in recent decades as a potential solution for disease diagnostics and therapy follow-up at the point-of-care (POC). [...]
2018 - 10.1080/14737159.2019.1554435
Expert review of molecular diagnostics, Vol. 19, Issue 1 (December 2018) , p. 71-81
2 documents

Articles : 13 records found   1 - 10next  jump to record:
Research literature 1 records found  
1.
217 p, 6.6 MB Nanophotonic biosensors for deciphering cell regulation pathways / Huertas, César S ; Lechuga, Laura, dir. ; Villaverde, Antoni ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
La presente Tesis Doctoral se centra en el desarrollo de metodologías analíticas de carácter innovador para el estudio de diferentes rutas de regulación genética. Éstas nuevas técnicas de análisis se presentan como una atractiva alternativa para conseguir un diagnóstico y seguimiento de terapia del cáncer más precisos e informativos. [...]
This Doctoral Thesis focuses on the development of innovative biosensor devices as alternative analytical techniques for the evaluation of different gene regulating pathways in order to obtain a more informative and accurate diagnosis and follow-up therapy of cancer. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  

See also: similar author names
1 Huertas, Carme
2 Huertas, César S.
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