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13 p, 823.6 KB Non-invasive vagus nerve stimulation (nVNS) for the preventive treatment of episodic migraine : The multicentre, double-blind, randomised, sham-controlled PREMIUM trial / Diener, Hans-Christoph (University Duisburg-Essen) ; Goadsby, Peter J. (King's College London) ; Ashina, Messoud (Glostrup University Hospital Copenhagen) ; Al-Karagholi, Mohammad Al-Mahdi (Glostrup University Hospital Copenhagen) ; Sinclair, Alexandra J. (Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham) ; Mitsikostas, Dimos (1st National and Kapodistrian University of Athens) ; Magis, Delphine (CHR East Belgium) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Irimia Sieira, Pablo (Clínica Universidad de Navarra) ; Làinez, Miguel J. A. (Universidad Católica de Valencia) ; Gaul, Charly (Migraine and Headache Clinic) ; Silver, Nicholas (The Walton Centre) ; Hoffmann, Jan (King's College London) ; Marin, Juana (King's College London) ; Liebler, Eric (electroCore, Inc., Basking Ridge) ; Ferrari, Michel D.. (Leiden University Medical Center) ; Universitat Autònoma de Barcelona
Non-invasive vagus nerve stimulation (nVNS; gammaCore®) has the potential to prevent migraine days in patients with migraine on the basis of mechanistic rationale and pilot clinical data. This multicentre study included a 4-week run-in period, a 12-week double-blind period of randomised treatment with nVNS or sham, and a 24-week open-label period of nVNS. [...]
2019 - 10.1177/0333102419876920
Cephalalgia, Vol. 39 (september 2019) , p. 1475-1487  

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