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13 p, 7.0 MB Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning / Mueller, Yvonne M. (Erasmus University Medical Center) ; Schrama, Thijs J. (Erasmus University Medical Center) ; Ruijten, Rik (Erasmus University Medical Center) ; Schreurs, Marco W. J. (Erasmus University Medical Center) ; Grashof, Dwin G. B. (Erasmus University Medical Center) ; van de Werken, Harmen J. G. (Erasmus University Medical Center) ; Lasinio, Giovanna Jona (University of Rome "La Sapienza") ; Álvarez-Sierra, Daniel (Hospital Universitari Vall d'Hebron) ; Kiernan, Caoimhe H. (Erasmus University Medical Center) ; Castro Eiro, Melisa D. (Erasmus University Medical Center) ; van Meurs, Marjan (Erasmus University Medical Center) ; Brouwers-Haspels, Inge (Erasmus University Medical Center) ; Zhao, Manzhi (Erasmus University Medical Center) ; Li, Ling (Erasmus University Medical Center) ; de Wit, Harm (Erasmus University Medical Center) ; Ouzounis, Christos A. (Chemical Process & Energy Resources Institute, Centre for Research & Technology Hellas, Thermi) ; Wilmsen, Merel E. P. (Erasmus University Medical Center) ; Alofs, Tessa M. (Erasmus University Medical Center) ; Laport, Danique A. (Erasmus University Medical Center) ; van Wees, Tamara (Erasmus University Medical Center) ; Kraker, Geoffrey (Cytek Biosciences, Fremont, CA USA) ; Jaimes, Maria C. (Cytek Biosciences, Fremont, CA USA) ; Van Bockstael, Sebastiaan (Cytek Biosciences, Fremont, CA USA) ; Hernández-González, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rokx, Casper (Erasmus University Medical Center) ; Rijnders, Bart J. A. (Erasmus University Medical Center) ; Pujol-Borrell, Ricardo (Vall d'Hebron Institut d'Oncologia) ; Katsikis, Peter D. (Erasmus University Medical Center) ; Universitat Autònoma de Barcelona
Quantitative or qualitative differences in immunity may drive clinical severity in COVID-19. Although longitudinal studies to record the course of immunological changes are ample, they do not necessarily predict clinical progression at the time of hospital admission. [...]
2022 - 10.1038/s41467-022-28621-0
Nature communications, Vol. 13 (february 2022)  
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