Resultados globales: 2 registros encontrados en 0.02 segundos.
Artículos, Encontrados 2 registros
Artículos Encontrados 2 registros  
11 p, 2.4 MB Oncometabolic nuclear reprogramming of cancer stemness / Menendez, Javier A. (Institut Català d'Oncologia) ; Corominas-Faja, Bruna (Institut d'Investigació Biomèdica de Girona) ; Cuyàs, Elisabet (Institut d'Investigació Biomèdica de Girona) ; García, María G. (Instituto Universitario de Oncología del Principado de Asturias) ; Fernández-Arroyo, Salvador (Hospital Universitari de Sant Joan) ; Fernández, Agustín F. (Instituto Universitario de Oncología del Principado de Asturias) ; Joven, Jorge (Hospital Universitari de Sant Joan) ; Fraga, Mario F. (Instituto Universitario de Oncología del Principado de Asturias) ; Alarcón Cor, Tomás (Centre de Recerca Matemàtica)
By impairing histone demethylation and locking cells into a reprogramming-prone state, oncometabolites can partially mimic the process of induced pluripotent stem cell generation. Using a systems biology approach, combining mathematical modeling, computation, and proof-of-concept studies with live cells, we found that an oncometabolite-driven pathological version of nuclear reprogramming increases the speed and efficiency of dedifferentiating committed epithelial cells into stem-like states with only a minimal core of stemness transcription factors. [...]
2016 - 10.1016/j.stemcr.2015.12.012
Stem cell reports, Vol. 6, issue 3 (March 2016) , p. 273-283  
9 p, 567.0 KB Risk of hyperkalemia in patients with moderate chronic kidney disease initiating angiotensin converting enzyme inhibitors or angiotensin receptor blockers : a randomized study / Espinel Garuz, Eugenia (Vall d'Hebron Hospitals) ; Joven Maried, Jorge (Universitat Rovira i Virgili) ; Gil, Iván (Vall d'Hebron Hospitals) ; Suñé, Pilar (Vall d'Hebron Hospitals) ; Renedo, Berta (Vall d'Hebron Hospitals) ; Fort Ros, Joan (Vall d'Hebron Hospitals) ; Serón Micas, Daniel (Vall d'Hebron Hospitals)
Background: Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers are renoprotective but both may increase serum potassium concentrations in patients with chronic kidney disease (CKD). [...]
2013 - 10.1186/1756-0500-6-306
BMC Public health, Vol. 6, N. 306 (August 2013) , p. 1-9  

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