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11 p, 946.8 KB |
APRIL : A double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke
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Hernández-Jiménez, Macarena (AptaTargets (Madrid)) ;
Abad-Santos, Francisco (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Cotgreave, Ian (Research Institutes of Sweden) ;
Gallego, Jaime (Neurological Center of Navarra) ;
Jilma, Bernd (Medical University of Vienna) ;
Flores, Alan (Hospital Universitari Joan XXIII de Tarragona) ;
Jovin, Tudor G. (Cooper Neurological Institute) ;
Vivancos, José (Hospital Universitario de la Princesa (Madrid)) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montaner, Joan (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Casariego, Joaquín (Aldebaran Health Intelligence (Madrid)) ;
Dalsgaard, Mads (Cureteq AG) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Liebeskind, David S. (UCLA Stroke Center) ;
Cobo, Erik (Universitat Politècnica de Catalunya. BarcelonaTech) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
In the reperfusion era, a new paradigm of treating patients with endovascular treatment (EVT) and neuroprotective drugs is emerging as a promising therapeutic option for patients with acute ischemic stroke (AIS). [...]
2023 -  10.3389/fneur.2023.1127585
Frontiers in neurology, Vol. 14 (february 2023)
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9 p, 841.9 KB |
Endovascular Treatment Effect Diminishes With Increasing Thrombus Perviousness
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Kappelhof, Manon (Amsterdam Universitair Medische Centra (Amsterdam, Països Baixos)) ;
Tolhuisen, Manon L. (Biomedical Engineering and Physics) ;
Treurniet, Kilian M. (Radiology and Nuclear Medicine) ;
Dutra, Bruna G. (Biomedical Engineering and Physics) ;
Alves, Heitor (Biomedical Engineering and Physics) ;
Zhang, Guang (Radiology and Nuclear Medicine) ;
Brown, Scott (Altair Biostatistics) ;
Muir, Keith W. (Queen Elizabeth University Hospital) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roos, Yvo B. W. E. M. (University of Amsterdam) ;
Saver, Jeffrey L.. (University of California) ;
Demchuk, Andrew (University of Calgary) ;
Jovin, Tudor G. (University of Pittsburgh Medical Center) ;
Bracard, Serge (University of Lorraine) ;
Campbell, Bruce C.V (Royal Melbourne Hospital (Melbourne, Austràlia)) ;
van der Lugt, Aad (Erasmus Medical Center) ;
Guillemin, Francis (University Hospital of Nancy) ;
White, Philip (Institute of Neuroscience) ;
Hill, M. D (University of Calgary) ;
Dippel, Diederik W. J. (Erasmus Medical Center) ;
Mitchell, Peter J. (Royal Melbourne Hospital (Melbourne, Austràlia)) ;
Goyal, Mayank (University of Calgary) ;
Marquering, Henk A. (Biomedical Engineering and Physics) ;
Majoie, Charles B. L. M. (Radiology and Nuclear Medicine) ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. Thrombus perviousness estimates residual flow along a thrombus in acute ischemic stroke, based on radiological images, and may influence the benefit of endovascular treatment for acute ischemic stroke. [...]
2021 - 10.1161/STROKEAHA.120.033124
Stroke, Vol. 52 (july 2021) , p. 3633-3641
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7 p, 570.4 KB |
Effect of atrial fibrillation on endovascular thrombectomy for acute ischemic stroke. A meta-analysis of individual patient data from six randomised trials : Results from the HERMES collaboration
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Smaal, J. A. (Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM)) ;
de Ridder, I. R. (Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM)) ;
Heshmatollah, A. (Erasmus MC University Medical Center) ;
van Zwam, W. H. (Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM)) ;
Dippel, DWJ (Erasmus MC University Medical Center) ;
Majoie, C. B. (Amsterdam UMC. University Medical Center) ;
Brown, S. (Altair Biostatistics) ;
Goyal, M. (University of Calgary, Foothills Hospital) ;
Campbell, Bruce C.V (Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne) ;
Muir, Keith W. (Institute of Neuroscience and Psychology, University of Glasgow, Queen Elizabeth University Hospital) ;
Demchuck, A. M. (University of Calgary, Foothills Hospital) ;
Dávalos, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Jovin, T. G. (Stroke Institute, Department of Neurology, University of Pittsburgh Medical Center) ;
Mitchell, P. J. (Royal Melbourne Hospital (Melbourne, Austràlia)) ;
White, P. (Institute of Neuroscience, Newcastle University) ;
Saver, J. L. (Department of Neurology, Amsterdam University Medical Centers) ;
Hill, M. D. (Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Foothills Hospital) ;
Roos, Y. B. (Department of Neurology, Amsterdam University Medical Centers) ;
van der Lugt, A. (Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center) ;
van Oostenbrugge, R. J. (Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM))
Atrial fibrillation is an important risk factor for ischemic stroke, and is associated with an increased risk of poor outcome after ischemic stroke. Endovascular thrombectomy is safe and effective in acute ischemic stroke patients with large vessel occlusion of the anterior circulation. [...]
2020 - 10.1177/2396987320923447
European Stroke Journal, Vol. 5 (may 2020) , p. 245-251
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11 p, 4.2 MB |
Cerebrovascular events and outcomes in hospitalized patients with COVID-19 : The SVIN COVID-19 Multinational Registry
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Siegler, James E. (Cooper Medical School of Rowan University) ;
Cardona, Pere-Joan (Hospital Universitari de Bellvitge) ;
Arenillas, Juan F.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Megahed, Mohammed (Alexandria University) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Requena, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jillella, Dinesh (Universitat Autònoma de Barcelona) ;
Talavera, Blanca (Hospital Universitari de Bellvitge) ;
Tiu, Cristina (University Emergency Hospital Bucharest) ;
Terecoasa, Elena O. (University Emergency Hospital Bucharest) ;
Radu, Răzvan A. (Alexandria University) ;
Nguyen, Thanh N. (Boston University School of Medicine) ;
Curiale, Gioacchino ("Carol Davila" University of Medicine and Pharmacy) ;
Kaliaev, Artem (Boston University School of Medicine) ;
Czap, Alexandra L. (Boston University School of Medicine) ;
Sebaugh, Jacob (Boston University School of Medicine) ;
Zha, Alicia M. (Boston University School of Medicine) ;
Liebeskind, David S. (University of Texas Health Science Center) ;
Ortega-Gutierrez, Santiago (Ronald Reagan UCLA Medical Center) ;
Farooqui, Mudassir (Ronald Reagan UCLA Medical Center) ;
Hassan, Ameer E. (Valley Baptist Medical Center) ;
Preston, Laurie (University of Iowa Hospitals and Clinics) ;
Patterson, Mary S. (University of Texas Rio Grande Valley) ;
Bushnaq, Saif (University of Texas Rio Grande Valley) ;
Zaidat, Osama (University of Texas Rio Grande Valley) ;
Jovin, Tudor G. (Cooper Medical School of Rowan University) ;
Universitat Autònoma de Barcelona
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has been associated with a significant risk of thrombotic events in critically ill patients. To summarize the findings of a multinational observational cohort of patients with SARS-CoV-2 and cerebrovascular disease. [...]
2020 - 10.1177/1747493020959216
International Journal of Stroke, september 2020
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9 p, 730.3 KB |
Safety and Efficacy of Solitaire Stent Thrombectomy
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Campbell, Bruce C.V ;
Hill, M. D ;
Rubiera Del Fueyo, Marta A ;
Menon, Bijoy K. ;
Demchuk, Andrew ;
Donnan, Geoffrey A. ;
Roy, Daniel ;
Thornton, John ;
Dorado Bouix, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bonafe, Alain ;
Levy, Elad I. ;
Diener, Hans-Christoph ;
Hernández-Pérez, María ;
Pereira, Vitor Mendes ;
Blasco, Jordi ;
Quesada, Helena ;
Rempel, Jeremy ;
Jahan, Reza ;
Davis, Stephen M. ;
Stouch, Bruce C. ;
Mitchell, Peter J. ;
Jovin, Tudor G. ;
Saver, Jeffrey L.. ;
Goyal, Mayank ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. Patient-level data were pooled from trials in which the Solitaire was the only or the predominant device used in a prespecified meta-analysis (SEER Collaboration): Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment (SWIFT PRIME), Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times (ESCAPE), Extending the Time for Thrombolysis in Emergency Neurological Deficits-Intra-Arterial (EXTEND-IA), and Randomized Trial of Revascularization With Solitaire FR Device Versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting Within Eight Hours of Symptom Onset (REVASCAT). [...]
2016 - 10.1161/STROKEAHA.115.012360
Stroke, Vol. 47 (february 2016) , p. 798-806
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