Resultados globales: 4 registros encontrados en 0.02 segundos.
Artículos, Encontrados 3 registros
Documentos de investigación, Encontrados 1 registros
Artículos Encontrados 3 registros  
1.
11 p, 1.0 MB IgIDivA : immunoglobulin intraclonal diversification analysis / Zaragoza-Infante, Laura (Aristotle University of Thessalonik) ; Junet, Valentin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pechlivanis, Nikos (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ; Fragkouli, Styliani-Christina (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ; Amprachamian, Serovpe (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ; Koletsa, Triantafyllia (Aristotle University of Thessaloniki) ; Chatzidimitriou, Anastasia (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ; Papaioannou, Maria (Aristotle University of Thessaloniki) ; Stamatopoulos, Kostas (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ; Agathangelidis, Andreas (University of Athens) ; Psomopoulos, Fotis (Centre for Research and Technology Hellas (Tessalònica, Grècia))
Intraclonal diversification (ID) within the immunoglobulin (IG) genes expressed by B cell clones arises due to ongoing somatic hypermutation (SHM) in a context of continuous interactions with antigen(s). [...]
2022 - 10.1093/bib/bbac349
Briefings in Bioinformatics, Vol. 23, Issue 5 (September 2022) , art. bbac349  
2.
9 p, 748.7 KB CuBlock : a cross-platform normalization method for gene-expression microarrays / Junet, Valentin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Farrés, Judith (Anaxomics Biotech SL) ; Mas, José M. (Anaxomics Biotech SL) ; Daura i Ribera, Xavier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Cross-(multi)platform normalization of gene-expression microarray data remains an unresolved issue. Despite the existence of several algorithms, they are either constrained by the need to normalize all samples of all platforms together, compromising scalability and reuse, by adherence to the platforms of a specific provider, or simply by poor performance. [...]
2021 - 10.1093/bioinformatics/btab105
Bioinformatics, Vol. 37, Issue 16 (August 2021) , p. 2365-2373  
3.
16 p, 1.4 MB In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan / Jorba, Guillem (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Aguirre-Plans, Joaquim (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Junet, Valentin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Segú-Vergés, Cristina (Anaxomics Biotech SL) ; Ruiz, José Luis (Anaxomics Biotech SL) ; Pujol, Albert (Anaxomics Biotech SL) ; Fernández-Fuentes, Narcís (Universitat de Vic - Universitat Central de Catalunya. Departament de Biociències) ; Mas, José Manuel (Anaxomics Biotech SL) ; Oliva Miguel, Baldomero (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut)
Unveiling the mechanism of action of a drug is key to understand the benefits and adverse reactions of a medication in an organism. However, in complex diseases such as heart diseases there is not a unique mechanism of action but a wide range of different responses depending on the patient. [...]
2020 - 10.1371/journal.pone.0228926
PloS one, Vol. 15, Núm. 2 (February 2020) , art. e0228926  

Documentos de investigación Encontrados 1 registros  
1.
9.1 MB Machine Learning techniques in bioinformatics : From data integration to the development of application-oriented tools / Junet, Valentin ; Daura i Ribera, Xavier, dir. ; Mas, José Manuel, dir.
Els darrers desenvolupaments en Machine Learning tenen com a objectiu automatitzar els mètodes disponibles, convertint-los en universals alhora que requerint el mínim coneixement expert possible. En aquesta tesi, farem un pas enrere. [...]
Los desarrollos recientes en Machine Learning tienen como objetivo automatizar los métodos disponibles, haciéndolos universales y requiriendo el menor conocimiento experto posible. En esta tesis, daremos un paso atrás. [...]
Recent developments in Machine Learning aim at automatizing available methods, rendering them universal while requiring as little expert-knowledge as possible. In this thesis, we will take a step back. [...]
Universitat Autònoma de Barcelona. Programa de Doctorat en Bioinformàtica.

2022  

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