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10 p, 306.7 KB A single dose of pegfilgrastim compared with daily filgrastim for supporting neutrophil recovery in patients treated for low-tointermediate risk acute myeloid leukemia : results from a randomized, double-blind, phase 2 tria / Sierra Gil, Jorge (Institut d'Investigació Biomèdica Sant Pau) ; Szer, Jeffrey (Royal Melbourne Hospital (Melbourne, Austràlia)) ; Kassis, Jeannine (Hospital Maisonneuve-Rosemont (Montreal, Canadà)) ; Herrmann, Richard (Royal Perth Hospital (Perth, Austràlia)) ; Lazzarino, Mario (University of Pavia (Itàlia)) ; Thomas, Xavier (Edouard Herriot Hospital (Lyon, França)) ; Noga, Stephen J. (Alvin and Lois Lapidus Cancer Institute (Baltimore, Estats Units d'Amèrica)) ; Baker, Nigel (Biostatistics, Amgen Ltd. (Cambridge, Regne Unit)) ; Dansey, Roger (Clinical Development, Amgen Inc. (Thousand Oaks, Estats Units d'Amèrica)) ; Bosi, Alberto (University of Florence (Itàlia). Department of Critical Care) ; Universitat Autònoma de Barcelona
Background: Patients with acute myeloid leukemia (AML) are often neutropenic as a result of their disease. Furthermore, these patients typically experience profound neutropenia following induction and/or consolidation chemotherapy and this may result in serious, potentially life-threatening, infection. [...]
2008 - 10.1186/1471-2407-8-195
BMC Cancer, Vol. 8, N. 195 (July 2008) , p. 1-10  

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