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Articles, 2 records found
Articles 2 records found  
1.
19 p, 9.0 MB Osmostress-Induced Apoptosis in Xenopus Oocytes : Role of Stress Protein Kinases, Calpains and Smac/DIABLO / Ben Messaoud, Nabil (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Yue, Jicheng (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Valent, Daniel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Katzarova, Ilina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Hyperosmotic shock induces cytochrome c release and capase-3 activation in Xenopus oocytes, but the regulators and signaling pathways involved are not well characterized. Here we show that hyperosmotic shock induces rapid calpain activation and high levels of Smac/DIABLO release from the mitochondria before significant amounts of cytochrome c are released to promote caspase-3 activation. [...]
2015 - 10.1371/journal.pone.0124482
PLoS one, Vol. 10, Num. 4 (2015) , p. 1-19  
2.
15 p, 2.0 MB Basic Properties of the p38 Signaling Pathway in Response to Hyperosmotic Shock / Ben Messaoud, Nabil (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Katzarova, Ilina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Some properties of signaling systems, like ultrasensitivity, hysteresis (a form of biochemical memory), and all-or-none responses at a single cell level, are important to understand the regulation of irreversible processes. [...]
2015 - 10.1371/journal.pone.0135249
PLoS one, Vol. 10, Num. 9 (September 2015) , p. 1-15  

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