Klappe, Karin - Search Results - UAB Digital Repository of Documents

Search collections:

Sort by:	Display results:	Output format:

Results overview: Found 2 records in 0.02 seconds.
Articles, 2 records found

Articles	2 records found

17 p, 2.5 MB

A Molecular Mechanism Underlying Genotype-Specific Intrahepatic Cholestasis Resulting From MYO5B Mutations / Overeem, Arend W. (University Medical Center Groningen) ; Li, Qinghong (University Medical Center Groningen) ; Qiu, Yi-Ling (Children's Hospital of Fudan University, Shanghai) ; Cartón-Garcia, Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Leng, Changsen (University Medical Center Groningen) ; Klappe, Karin (University Medical Center Groningen) ; Dronkers, Just (University Medical Center Groningen) ; Hsiao, Nai-Hua (University Medical Center Groningen) ; Wang, Jian-She (Children's Hospital of Fudan University, Shanghai) ; Arango, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; van Ijzendoorn, Sven C. D. (University Medical Center Groningen) ; Universitat Autònoma de Barcelona
Progressive familial intrahepatic cholestasis (PFIC) 6 has been associated with missense but not biallelic nonsense or frameshift mutations in MYO5B, encoding the motor protein myosin Vb (myoVb). This genotype-phenotype correlation and the mechanism through which MYO5B mutations give rise to PFIC are not understood. [...]
2020 - DOI (Digital Object Identifier)

10.1002/hep.31002
Hepatology, Vol. 72 (april 2020) , p. 213-229

Detailed record -

29 p, 6.1 MB

Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation / Leng, Changsen (Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands) ; Overeem, Arend W. (Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands) ; Cartón-Garcia, Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Li, Qinghong (Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen) ; Klappe, Karin (Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen) ; Kuipers, Jeroen (Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen) ; Cui, Yingying (Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen) ; Zuhorn, Inge S. (Department of Biomedical Engineering, University of Groningen, University Medical Center Groningen) ; Arango, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; van IJzendoorn, Sven C. D. (Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen) ; Universitat Autònoma de Barcelona
Recycling endosomes regulate plasma membrane recycling. Recently, recycling endosome-associated proteins have been implicated in the positioning and orientation of the mitotic spindle and cytokinesis. [...]
2019 - DOI (Digital Object Identifier)

10.1371/journal.pbio.3000531
PLoS biology, Vol. 17 (november 2019)

Detailed record -

See also: similar author names
1	Klappe, K.

Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.