Kontsevaya, Irina - Resultados de la búsqueda - Depósito Digital de Documentos de la UAB

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16 p, 657.0 KB

Perspectives for systems biology in the management of tuberculosis / Kontsevaya, Irina (University of Lübeck) ; Lange, Christoph (University of Lübeck) ; Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Coarfa, Cristian (Baylor College of Medicine) ; DiNardo, Andrew R. (The Baylor College of Medicine) ; Gillespie, Stephen H. (University of St Andrew) ; Hauptmann, Matthias (Hamburg-Lübeck-Borstel-Riems) ; Leschczyk, Christoph (Hamburg-Lübeck-Borstel-Riems) ; Mandalakas, Anna M. (Baylor College of Medicine) ; Martinecz, Antal (Arctic University of Norway) ; Merker, Matthias (Hamburg-Lübeck-Borstel-Riems) ; Niemann, Stefan (Hamburg-Lübeck-Borstel-Riems) ; Reimann, Maja (University of Lübeck) ; Rzhepishevska, Olena (Umeå University (Suècia)) ; Schaible, Ulrich E. (Hamburg-Lübeck-Borstel-Riems) ; Scheu, Katrin M. (Research Center Borstel) ; Schurr, Erwin (Research Institute of the McGill University Health Centre (Montréal, Canada)) ; Abel zur Wiesch, Pia (Pennsylvania State University (Estats Units d'Amèrica)) ; Heyckendorf, Jan (University of Lübeck) ; Universitat Autònoma de Barcelona
Standardised management of tuberculosis may soon be replaced by individualised, precision medicine-guided therapies informed with knowledge provided by the field of systems biology. Systems biology is a rapidly expanding field of computational and mathematical analysis and modelling of complex biological systems that can provide insights into mechanisms underlying tuberculosis, identify novel biomarkers, and help to optimise prevention, diagnosis and treatment of disease. [...]
2021 - DOI (Digital Object Identifier)

10.1183/16000617.0377-2020
European Respiratory Review, Vol. 30 (may 2021)

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17 p, 2.5 MB

Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles / Benet, Susana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Drobniewski, Francis (Imperial College) ; Kontsevaya, Irina (N.V. Postnikov Samara Region Clinical Tuberculosis Dispensary) ; Arias, Lilibeth (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Monguió-Tortajada, Marta (Universitat Autònoma de Barcelona) ; Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ong, Ruo-Yan (University of Dundee) ; Luquín Fernández, Marina (Marina) (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Dupont, Maeva (International associated laboratory (LIA) CNRS "IM-TB/HIV" (1167)) ; Chojnacki, Jakub (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cardona, Paula (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Neyrolles, Olivier (International associated laboratory (LIA) CNRS "IM-TB/HIV" (1167)) ; Lugo-Villarino, Geanncarlo (International associated laboratory (LIA) CNRS "IM-TB/HIV" (1167)) ; Vérollet, Christel (International associated laboratory (LIA) CNRS "IM-TB/HIV" (1167)) ; Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Furrer, Hansjakob (University of Bern) ; Günthard, Huldrych F. (University of Zurich) ; Crocker, Paul R. (University of Dundee) ; Tapia, Gustavo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Borràs i Serres, Francesc Enric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Fellay, Jacques (Lausanne University Hospital) ; McLaren, Paul J. (University of Manitoba) ; Telenti, Amalio (The Scripps Research Institute) ; Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Izquierdo Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
The identification of individuals with null alleles enables studying how the loss of gene function affects infection. We previously described a non-functional variant in SIGLEC1, which encodes the myeloid-cell receptor Siglec-1/CD169 implicated in HIV-1 cell-to-cell transmission. [...]
2021 - DOI (Digital Object Identifier)

10.1002/jev2.12046
Journal of extracellular vesicles, Vol. 10 (january 2021)

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