Home > Search Results: Kopetz, Scott
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Articles, 2 records found
Articles 2 records found  
1.
19 p, 418.6 KB Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With BRAF V600E-Mutant Metastatic Colorectal Cancer : Safety Lead-In Results From the Phase III BEACON Colorectal Cancer Study / Van Cutsem, Eric (University Hospitals Gasthuisberg (Leuven, Bélgica)) ; Huijberts, Sanne (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Grothey, Axel (West Cancer Center, Germantown, TN) ; Yaeger, Rona (Memorial Sloan Kettering Cancer Center) ; Cuyle, Pieter-Jan (University Hospitals Gasthuisberg (Leuven, Bélgica)) ; Elez, Elena (Vall d'Hebron Institut d'Oncologia) ; Fakih, Marwan (City of Hope National Medical Center (Duarte, Estats Units d'Amèrica)) ; Montagut, Clara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Peeters, Marc (University Hospital Antwerp (Bèlgica)) ; Yoshino, Takayuki (National Cancer Center Hospital East, Kashiwa, Japan) ; Wasan, Harpreet (Hammersmith Hospital (Londres)) ; Desai, Jayesh (Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia) ; Ciardiello, Fortunato (University of Campania "Luigi Vanvitelli" (Nàpols, Itàlia)) ; Gollerkeri, Ashwin (Array BioPharma Inc) ; Christy-Bittel, Janna (Array BioPharma Inc) ; Maharry, Kati (Array BioPharma Inc) ; Sandor, Victor (Array BioPharma Inc) ; Schellens, Jan H. M. (Utrecht University) ; Kopetz, Scott (The University of Texas MD Anderson Cancer Center, Houston, TX) ; Tabernero, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; Vall d'Hebron Institut de Recerca (VHIR)
To determine the safety and preliminary efficacy of selective combination targeted therapy for BRAF V600E-mutant metastatic colorectal cancer (mCRC) in the safety lead-in phase of the open-label, randomized, three-arm, phase III BEACON Colorectal Cancer trial ( identifier: ; European Union Clinical Trials Register identifier: EudraCT2015-005805-35). [...]
2019 - 10.1200/JCO.18.02459
Journal of Clinical Oncology, Vol. 37 (march 2019) , p. 1460-1469  
Detailed record - Creative Commons
2.
33 p, 1.9 MB The Consensus Molecular Subtypes of Colorectal Cancer / Guinney, Justin (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Dienstmann, Rodrigo (Vall d'Hebron Institut d'Oncologia) ; Wang, Xin (City University of Hong Kong. Department of Biomedical Sciences (China)) ; de Reyniès, Aurélien (Ligue Nationale Contre le Cancer (France)) ; Schlicker, Andreas (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Soneson, Charlotte (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Marisa, Laetitia (Ligue Nationale Contre le Cancer (France)) ; Roepman, Paul (Agendia NV (Netherlands)) ; Nyamundanda, Gift (The Institute of Cancer Research (UK)) ; Angelino, Paolo (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Bot, Brian M. (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Morris, Jeffrey S. (The University of Texas M.D. Anderson Cancer Center (USA)) ; Simon, Iris M. (Agendia NV (Netherlands)) ; Gerster, Sarah (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Fessler, Evelyn (University of Amsterdam (Netherlands)) ; de Sousa e Melo, Felipe (University of Amsterdam (Netherlands)) ; Missiaglia, Edoardo (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Ramay, Hena (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Barras, David (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Homicsko, Krisztian (Ecole Polytechnique Federale de Lausanne (Switzerland)) ; Maru, Dipen (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ; Manyam, Ganiraju C. (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ; Broom, Bradley (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ; Boige, Valerie (Gustave Roussy, Villejuif (France)) ; Perez-Villamil, Beatriz (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Laderas, Ted (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Salazar, Ramon (Institut d'Investigació Biomèdica de Bellvitge) ; Gray, Joe W. (Oregon Health Sciences University (USA)) ; Hanahan, Douglas (Ecole Polytechnique Federale de Lausanne (Switzerland)) ; Tabernero, Josep (Vall d'Hebron Institut d'Oncologia) ; Bernards, Rene (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Friend, Stephen H. (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Laurent-Puig, Pierre (Universite Paris Descartes (France)) ; Medema, Jan Paul (LEXOR, Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam (Netherlands)) ; Sadanandam, Anguraj (The Institute of Cancer Research (UK)) ; Wessels, Lodewyk (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Delorenzi, Mauro (University of Lausanne (Switzerland)) ; Kopetz, Scott (The University of Texas M.D. Anderson Cancer Center (USA)) ; Vermeulen, Louis (LEXOR, Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam (Netherlands)) ; Tejpar, Sabine (Universitair ziekenhuis Leuven (Belgium)) ; Universitat Autònoma de Barcelona
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression-based CRC classifications and facilitate clinical translation, we formed an international consortium dedicated to large-scale data sharing and analytics across expert groups. [...]
2015 - 10.1038/nm.3967
Nature Medicine, Vol. 21, Num. 11 (November 2015) , p. 1350-1356  
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1 Kopetz, S.
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