Resultats globals: 8 registres trobats en 0.02 segons.
Articles, 8 registres trobats
Articles 8 registres trobats  
1.
42 p, 2.1 MB Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis / Kanoni, Stavroula (Queen Mary University of London) ; Graham, Sarah E. (University of Michigan) ; Wang, Yuxuan (Boston University School of Public Health) ; Surakka, Ida (University of Michigan) ; Ramdas, Shweta (University of Pennsylvania) ; Zhu, Xiang (Stanford University) ; Clarke, Shoa L. (Stanford University School of Medicine) ; Bhatti, Konain Fatima (Queen Mary University of London) ; Vedantam, Sailaja (Broad Institute of MIT and Harvard) ; Winkler, Thomas W. (University of Regensburg) ; Locke, Adam E. (Washington University) ; Marouli, Eirini (Queen Mary University of London) ; Zajac, Greg J. M. (University of Michigan) ; Wu, Kuan-Han H. (University of Michigan) ; Ntalla, Ioanna (Queen Mary University of London) ; Hui, Qin (Atlanta VA Health Care System) ; Klarin, Derek (Stanford University School of Medicine) ; Hilliard, Austin T. (VA Palo Alto Health Care Systems) ; Wang, Zeyuan (Atlanta VA Health Care System) ; Xue, Chao (University of Michigan) ; Thorleifsson, Gudmar (deCODE Genetics/Amgen) ; Helgadottir, Anna (deCODE Genetics/Amgen) ; Gudbjartsson, Daniel F. (University of Iceland) ; Holm, Hilma (deCODE Genetics/Amgen) ; Olafsson, Isleifur (Landspitali - National University Hospital of Iceland) ; Hwang, Mi Yeong (National Institute of Health) ; Han, Sohee (National Institute of Health) ; Akiyama, Masato (Kyushu University) ; Sakaue, Saori (The University of Tokyo) ; Terao, Chikashi (RIKEN Center for Integrative Medical Sciences) ; Kanai, Masahiro (Harvard Medical School) ; Zhou, Wei (Massachusetts General Hospital) ; Brumpton, Ben M. (St Olav's University Hospital) ; Rasheed, Humaira (University of Oslo) ; Havulinna, Aki S. (Finnish Institute for Health and Welfare) ; Veturi, Yogasudha (University of Pennsylvania) ; Pacheco, Jennifer Allen (Northwestern University) ; Rosenthal, Elisabeth A. (University of Washington) ; Lingren, Todd (Cincinnati Children's Hospital Medical Center) ; Feng, QiPing (Vanderbilt University Medical Center) ; Kullo, Iftikhar J. (Mayo Clinic) ; Narita, Akira (Tohoku Medical Megabank Organization) ; Takayama, Jun (Tohoku Medical Megabank Organization) ; Martin, Hilary C. (Wellcome Trust Sanger Institute (Regne Unit)) ; Hunt, Karen A. (Queen Mary University of London) ; Trivedi, Bhavi (Queen Mary University of London) ; Haessler, Jeffrey (Fred Hutchinson Cancer Center) ; Giulianini, Franco (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Bradford, Yuki (University of Pennsylvania) ; Miller, Jason E. (University of Pennsylvania) ; Campbell, Archie (University of Edinburgh) ; Lin, Kuang (University of Oxford) ; Millwood, Iona Y. (University of Oxford) ; Rasheed, Asif (Center for Non-Communicable Diseases) ; Hindy, George (Qatar University College of Medicine) ; Faul, Jessica D. (University of Michigan) ; Zhao, Wei (University of Michigan) ; Weir, David R. (University of Michigan) ; Turman, Constance (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Huang, Hongyan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Graff, Mariaelisa (University of North Carolina) ; Choudhury, Ananyo (University of the Witwatersrand) ; Sengupta, Dhriti (University of the Witwatersrand) ; Mahajan, Anubha (University of Oxford) ; Brown, Michael R. (The University of Texas Health Science Center at Houston) ; Zhang, Weihua (London North West University Healthcare NHS Trust) ; Yu, Ketian (University of Michigan) ; Schmidt, Ellen M. (University of Michigan) ; Pandit, Anita (University of Michigan) ; Gustafsson, S (Uppsala University) ; Yin, Xianyong (University of Michigan) ; Luan, Jian'an (University of Cambridge School of Clinical Medicine) ; Zhao, Jing-Hua (University of Cambridge) ; Matsuda, Fumihiko (Kyoto University Graduate School of Medicine) ; Jang, Hye-Mi (National Institute of Health) ; Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Medina-Gomez, Carolina (University Medical Center Rotterdam) ; Pitsillides, Achilleas (Boston University School of Public Health) ; Hottenga, Jouke Jan (Amsterdam Public Health Research Institute) ; Wood, Andrew R. (University of Exeter Medical School) ; Ji, Yingji (University of Exeter Medical School) ; Gao, Zishan (German Research Center for Environmental Health) ; Haworth, Simon (University of Bristol) ; Yousri, Noha A. (Alexandria University) ; Mitchell, Ruth E. (University of Bristol) ; Chai, Jin Fang (National University of Singapore and National University Health System) ; Aadahl, Mette (University of Copenhagen) ; Bjerregaard, Anne A. (Bispebjerg and Frederiksberg Hospital) ; Yao, Jie (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Manichaikul, Ani (University of Virginia) ; Hwu, Chii-Min (Taipei Veterans General Hospital) ; Hung, Yi-Jen (National Defense Medical Center) ; Warren, Helen R. (Queen Mary University of London) ; Ramirez, Julia (Universidad de Zaragoza) ; Bork-Jensen, Jette (University of Copenhagen) ; Kårhus, Line L. (Bispebjerg and Frederiksberg Hospital) ; Goel, Anuj (University of Oxford) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Noordam, Raymond (Leiden University Medical Center) ; Mauro, Pala (Consiglio Nazionale Delle Ricerche) ; Matteo, Floris (Università Degli Studi Di Sassari) ; McDaid, Aaron F. (Swiss Institute of Bioinformatics) ; Marques-Vidal, Pedro (Lausanne University Hospital) ; Wielscher, Matthias (Imperial College London) ; Trompet, Stella (Leiden University Medical Center) ; Sattar, Naveed (BHF Glasgow Cardiovascular Research Centre) ; Møllehave, Line T. (Bispebjerg and Frederiksberg Hospital) ; Munz, Matthias (University of Lübeck) ; Zeng, Lingyao (Partner Site Munich Heart Alliance) ; Huang, Jianfeng (Fuwai Hospital) ; Yang, Bin (Fuwai Hospital) ; Poveda, Alaitz (Lund University Diabetes Center) ; Kurbasic, Azra (Lund University Diabetes Center) ; Lamina, Claudia (German Chronic Kidney Disease Study) ; Forer, Lukas (German Chronic Kidney Disease Study) ; Scholz, Markus (University of Leipzig) ; Galesloot, Tessel E. (Radboud University Medical Center) ; Bradfield, Jonathan Paul (Quantinuum Research LLC) ; Ruotsalainen, Sanni E. (University of Helsinki) ; Daw, E. Warwick (Washington University School of Medicine) ; Zmuda, Joseph M. (University of Pittsburgh) ; Mitchell, Jonathan S. (Affiliated Institute of the University of Lübeck) ; Fuchsberger, Christian (Affiliated Institute of the University of Lübeck) ; Christensen, Henry (Lillebaelt Hospital) ; Brody, Jennifer A. (University of Washington) ; Vazquez-Moreno, Miguel (Centro Medico Nacional Siglo XXI) ; Feitosa, Mary F. (Washington University School of Medicine) ; Wojczynski, Mary K. (Washington University School of Medicine) ; Wang, Zhe (The Charles Bronfman Institute for Personalized Medicine) ; Preuss, Michael H. (The Charles Bronfman Institute for Personalized Medicine) ; Mangino, Massimo (NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust) ; Christofidou, Paraskevi (King's College London) ; Verweij, Niek (University of Groningen) ; Benjamins, Jan W. (University of Groningen) ; Engmann, Jorgen (University College London) ; Tsao, Noah L. (University of Pennsylvania) ; Verma, Anurag (University of Pennsylvania) ; Slieker, Roderick C. (Leiden University Medical Center) ; Lo, Ken Sin (Montreal Université de Montréal) ; Zilhao, Nuno R. (Icelandic Heart Association) ; Le, Phuong (University of Toronto at Mississauga) ; Kleber, Marcus E. (SYNLAB MVZ Humangenetik Mannheim GmbH) ; Delgado, Graciela E. (Heidelberg University) ; Huo, Shaofeng (University of Chinese Academy of Sciences) ; Ikeda, Daisuke D. (Tokushima Research Institute) ; Iha, Hiroyuki (Tokushima Research Institute) ; Yang, Jian (The University of Queensland) ; Liu, Jun (University Medical Center Rotterdam) ; Demirkan, Ayşe (University of Surrey) ; Leonard, Hampton L. (Data Tecnica International) ; Marten, Jonathan (University of Edinburgh) ; Frank, Mirjam (University of Duisburg-Essen) ; Schmidt, Börge (University of Duisburg-Essen) ; Smyth, Laura J. (Queen's University of Belfast) ; Cañadas-Garre, Marisa (Instituto de Investigación Biosanitaria de Granada) ; Wang, Chaolong (Genome Institute of Singapore) ; Nakatochi, Masahiro (Nagoya University Graduate School of Medicine) ; Wong, Andrew (MRC Unit for Lifelong Health and Ageing at UCL) ; Hutri-Kähönen, Nina (Tampere University) ; Sim, Xueling (National University of Singapore and National University Health System) ; Xia, Rui (University of Texas Health Science Center at Houston) ; Huerta-Chagoya, Alicia (Instituto de Investigaciones Biomédicas (Mèxic)) ; Fernandez-Lopez, Juan Carlos (Instituto Nacional de Medicina Genómica) ; Lyssenko, Valeriya (University of Bergen) ; Nongmaithem, Suraj S. (Academy of Scientific and Innovative Research (AcSIR)) ; Bayyana, Swati (Academy of Scientific and Innovative Research (AcSIR)) ; Stringham, Heather M. (University of Michigan.) ; Irvin, Marguerite R. (University of Alabama at Birmingham) ; Oldmeadow, Christopher (Hunter Medical Research Institute) ; Kim, Han-Na (SAIHST, Sungkyunkwan University) ; Ryu, Seungho (Kangbuk Samsung Hospital) ; Timmers, Paul R. H. J. (University of Edinburgh) ; Arbeeva, Liubov (University of North Carolina) ; Dorajoo, Rajkumar (Duke-NUS Medical School) ; Lange, Leslie A. (University of Colorado) ; Prasad, Gauri (CSIR-Human Resource Development Centre) ; Lorés-Motta, Laura (Radboud University Nijmegen Medical Center) ; Pauper, Marc (Radboud University Nijmegen Medical Center) ; Long, Jirong (Vanderbilt University Medical Center) ; Li, Xiaohui (Harbor-UCLA Medical Center) ; Theusch, Elizabeth (University of California San Francisco) ; Takeuchi, Fumihiko (National Center for Global Health and Medicine) ; Spracklen, Cassandra N. (University of Massachusetts-Amherst) ; Loukola, Anu (University of Helsinki) ; Bollepalli, Sailalitha (University of Helsinki) ; Warner, Sophie C. (Glenfield Hospital) ; Wang, Ya Xing (Beijing Institute of Ophthalmology) ; Wei, Wen B. (Beijing Tongren Eye Center) ; Nutile, Teresa (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" - CNR) ; Ruggiero, Daniela (IRCCS Neuromed) ; Sung, Yun Ju (Washington University) ; Chen, Shufeng (Fuwai Hospital) ; Liu, Fangchao (Fuwai Hospital) ; Yang, Jingyun (Rush University Medical Center) ; Kentistou, Katherine A. (University of Edinburgh) ; Banas, Bernhard (University Hospital Regensburg) ; Nardone, Giuseppe Giovanni (IRCCS Burlo Garofolo) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Bielak, Lawrence F. (University of Michigan) ; Smith, Jennifer A. (University of Michigan) ; Hebbar, Prashantha (Dasman Diabetes Institute) ; Farmaki, Aliki-Eleni (University College London) ; Hofer, Edith (Medical University of Graz) ; Lin, Maoxuan (Massachusetts General Hospital Cancer Center) ; Concas, Maria Pina (IRCCS Burlo Garofolo) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research) ; van der Most, Peter J (University of Groningen) ; Pitkänen, Niina (University of Turku and Turku University Hospital) ; Cade, Brian E. (Harvard Medical School) ; van der Laan, Sander W (University Medical Center Utrecht) ; Chitrala, Kumaraswamy Naidu (University of Houston-Sugarland) ; Weiss, Stefan (University of Greifswald and University Medicine Greifswald) ; Bentley, Amy R. (National Human Genome Research Institute) ; Doumatey, Ayo P. (National Human Genome Research Institute) ; Adeyemo, Adebowale A. (National Human Genome Research Institute) ; Lee, Jong Young (Soonchunhyang Mirai Medical Center 173) ; Petersen, Eva R. B. (Hospital of Southern Jutlandy and Immunology) ; Nielsen, Aneta A. (Lillebaelt Hospital) ; Choi, Hyeok Sun (Hallym University) ; Nethander, Maria (University of Gothenburg) ; Freitag-Wolf, Sandra (Kiel University) ; Southam, Lorraine (Institute of Translational Genomics) ; Rayner, Nigel W. (University of Oxford) ; Wang, Carol A (University of Newcastle) ; Lin, Shih-Yi (National Defense Medical Center) ; Wang, Jun-Sing (National Yang Ming Chiao Tung University) ; Couture, Christian (Université Laval) ; Lyytikäinen, Leo-Pekka (Finnish Cardiovascular Research Center - Tampere) ; Nikus, Kjell (Finnish Cardiovascular Research Center - Tampere) ; Cuellar-Partida, Gabriel (University of Queensland Diamantina Institute) ; Vestergaard, Henrik (Bornholms Hospital) ; Hidalgo, Bertha (University of Alabama at Birmingham) ; Giannakopoulou, Olga (Queen Mary University of London) ; Cai, Qiuyin (Vanderbilt University Medical Center) ; Obura, Morgan O. (Amsterdam Public Health Research Institute) ; van Setten, Jessica (University Medical Center Utrecht) ; Li, Xiaoyin (Case Western Reserve University) ; Liang, Jingjing (Case Western Reserve University) ; Tang, Hua (Stanford University School of Medicine Stanford) ; Terzikhan, Natalie (University Medical Center Rotterdam) ; Shin, Jae Hun (Hallym University) ; Jackson, Rebecca D. (Ohio State University) ; Reiner, Alexander P. (University of Washington) ; Martin, Lisa Warsinger (George Washington University) ; Chen, Zhengming (University of Oxford) ; Li, Liming (Peking University Health Science Center) ; Kawaguchi, Takahisa (Kyoto University Graduate School of Medicine) ; Thiery, Joachim (University Hospital Leipzig) ; Bis, Joshua C (University of Washington) ; Launer, Lenore J. (National Institute On Aging) ; Li, Huaixing (University of Chinese Academy of Sciences) ; Nalls, Mike A. (Data Tecnica International) ; Raitakari, Olli T. (Turku University Hospital (Finlàndia)) ; Ichihara, Sahoko (Jichi Medical University School of Medicine) ; Wild, Sarah H. (University of Edinburgh) ; Nelson, Christopher P. (NIHR Leicester Biomedical Research Centre) ; Campbell, Harry (University of Edinburgh) ; Jäger, Susanne (German Center for Diabetes Research (DZD)) ; Nabika, Toru (Shimane University School of Medicine) ; Al-Mulla, Fahd (Dasman Diabetes Institute) ; Niinikoski, Harri (University of Turku) ; Braund, Peter S. (NIHR Leicester Biomedical Research Centre) ; Kolcic, Ivana (University of Split School of Medicine) ; Kovacs, Peter (University of Leipzig Medical Center) ; Giardoglou, Tota (Harokopio University) ; Katsuya, Tomohiro (Osaka University Graduate School of Medicine) ; de Kleijn, Dominique (University Medical Center Utrecht) ; de Borst, Gert J. (University Medical Center Utrecht) ; Kim, Eung Kweon (Yonsei University College of Medicine) ; Adams, Hieab H. H. (Universidad Adolfo Ibáñez) ; Ikram, M. Arfan (University Medical Center Rotterdam) ; Zhu, X (Case Western Reserve University) ; Asselbergs, Folkert W. (University Medical Center Utrecht) ; Kraaijeveld, Adriaan O. (University Medical Center Utrecht) ; Beulens, Joline W. J. (University Medical Centre Utrecht) ; Shu, Xiao-Ou (Vanderbilt University Medical Center) ; Rallidis, Loukianos S. (National and Kapodistrian University of Athens) ; Pedersen, Oluf (University of Copenhagen) ; Hansen, Torben (University of Copenhagen) ; Mitchell, Paul (University of Sydney) ; Hewitt, Alex W. (University of Melbourne) ; Kähönen, Mika (Tampere University) ; Pérusse, Louis (Institute of Nutrition and Functional Foods (INAF)) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Tönjes, Anke (University of Leipzig Medical Center) ; Chen, Yii Der Ida (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Pennell, Craig E. (University of Newcastle) ; Mori, Trevor A. (The University of Western Australia) ; Lieb, Wolfgang (Kiel University) ; Franke, Andre (Kiel University) ; Ohlsson, Claes (Sahlgrenska University Hospital (Suècia)) ; Mellström, Dan (University of Gothenburg) ; Cho, Yoon Shin (Hallym University) ; Lee, Hyejin (EwhaWomans University School of Medicine) ; Yuan, Jian-Min (University of Pittsburgh) ; Koh, Woon-Puay (Singapore Institute for Clinical Sciences) ; Rhee, Sang Youl (Kyung Hee University School of Medicine) ; Woo, Jeong-Taek (Kyung Hee University School of Medicine) ; Heid, Iris M. (University of Regensburg) ; Stark, Klaus J. (University of Regensburg) ; Zimmermann, Martina E. (University of Regensburg) ; Völzke, Henry (University Medicine Greifswald) ; Homuth, Georg (University of Greifswald and University Medicine Greifswald) ; Evans, Michele K. (National Institute On Aging Intramural Research Program) ; Zonderman, Alan B. (National Institute On Aging Intramural Research Program) ; Polasek, Ozren (Algebra University College) ; Pasterkamp, Gerard (University Medical Center Utrecht) ; Hoefer, Imo E. (University Medical Center Utrecht) ; Redline, Susan (Harvard Medical School) ; Pahkala, Katja (University of Turku) ; Oldehinkel, Albertine J. (University of Groningen) ; Snieder, Harold (University Medical Center Groningen) ; Biino, Ginevra (National Research Council of Italy) ; Schmidt, Reinhold (Medical University of Graz) ; Schmidt, Helena (Medical University of Graz) ; Bandinelli, Stefania (Local Health Unit Toscana Centro) ; Dedoussis, George (Harokopio University of Athens) ; Thanaraj, Thangavel Alphonse (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Kardia, Sharon L. R. (University of Michigan) ; Peyser, Patricia A. (University of Michigan) ; Kato, Norihiro (National Center for Global Health and Medicine) ; Schulze, Matthias B. (University of Potsdam) ; Girotto, Giorgia (University of Trieste) ; Böger, Carsten A. (KfH Kidney Center Traunstein) ; Jung, Bettina (KfH Kidney Center Traunstein) ; Joshi, Peter K. (University of Edinburgh) ; Bennett, David A. (Rush University Medical Center) ; De Jager, Philip L. (Columbia University Medical Center) ; Lu, Xiangfeng (Fuwai Hospital) ; Mamakou, Vasiliki (Dromokaiteio Psychiatric Hospital) ; Brown, Morris (Queen Mary University of London) ; Caulfield, Mark J. (Queen Mary University of London) ; Munroe, Patricia B. (Queen Mary University of London) ; Guo, Xiuqing (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Ciullo, Marina (IRCCS Neuromed) ; Jonas, Jost B. (Privatpraxis Prof Jonas Und Dr Panda-Jonas) ; Samani, Nilesh J. (NIHR Leicester Biomedical Research Centre) ; Kaprio, Jaakko (University of Helsinki) ; Pajukanta, Päivi (University of California) ; Tusié-Luna, Teresa (Instituto de Investigaciones Biomédicas UNAM/ Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ; Aguilar-Salinas, Carlos Alberto (Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ; Adair, Linda S. (University of North Carolina) ; Bechayda, Sonny Augustin (University of San Carlos) ; de Silva, H. Janaka (University of Kelaniya) ; Wickremasinghe, Ananda R. (University of Kelaniya) ; Krauss, Ronald M. (Children's Hospital Oakland Research Institute) ; Wu, Jer-Yuarn (Institute of Biomedical Sciences) ; Zheng, Wei (Vanderbilt University Medical Center) ; Hollander, Anneke Iden (Radboud University Nijmegen Medical Center) ; Bharadwaj, Dwaipayan (Jawaharlal Nehru University) ; Correa, Adolfo (University of Mississippi Medical Center) ; Wilson, James G. (University of Mississippi Medical Center) ; Lind, Lars (Uppsala University) ; Heng, Chew-Kiat (Yong Loo Lin School of Medicine) ; Nelson, Amanda E. (University of North Carolina) ; Golightly, Yvonne M. (University of North Carolina) ; Wilson, James F. (University of Edinburgh) ; Penninx, Brenda (Vrije Universiteit Amsterdam) ; Kim, Hyung-Lae (Ewha Womans University) ; Attia, John (University of Newcastle) ; Scott, Rodney J. (University of Newcastle) ; Rao, D. C. (Washington University School of Medicine) ; Arnett, Donna K. (University of South Carolina) ; Hunt, Steven C. (University of Utah) ; Walker, Mark (Institute of Cellular Medicine (Diabetes)) ; Koistinen, Heikki A. (Minerva Foundation Institute for Medical Research) ; Chandak, Giriraj R. (JSS Academy of Higher Education and Research) ; Mercader, Josep M. (Harvard Medical School) ; Costanzo, Maria C. (Broad Institute of MIT and Harvard) ; Jang, Dongkeun (Broad Institute of MIT and Harvard) ; Burtt, Noël P. (Broad Institute of MIT and Harvard) ; Villalpando, Clicerio Gonzalez (InstitutoNacional de Salud Publica Y Centro de Estudios en Diabetes (Mèxic)) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Fornage, Myriam (University of Texas Health Science at Houston) ; Tai, EShyong (Yong Loo Lin School of Medicine) ; van Dam, Rob M. (Milken Institute School of Public Health) ; Lehtimäki, Terho (Finnish Cardiovascular Research Center - Tampere) ; Chaturvedi, Nish (MRC Unit for Lifelong Health and Ageing at UCL) ; Yokota, Mitsuhiro (Kurume University School of Medicine) ; Liu, Jianjun (Genome Institute of Singapore) ; Reilly, Dermot F. (Merck Sharp & Dohme Corp.. Genetics) ; McKnight, Amy Jayne (Queen's University of Belfast) ; Kee, Frank (Queen's University of Belfast) ; Jöckel, Karl-Heinz (University of Duisburg-Essen) ; McCarthy, Mark I. (University of Oxford) ; Palmer, Colin N. A. (University of Dundee) ; Vitart, Veronique (University of Edinburgh) ; Hayward, Caroline (University of Edinburgh) ; Simonsick, Eleanor (National Institute On Aging) ; van Duijn, Cornelia M. (University Medical Center Rotterdam) ; Jin, Zi-Bing (Wenzhou Medical University) ; Qu, Jia (Wenzhou Medical University) ; Hishigaki, Haretsugu (Tokushima Research Institute) ; Lin, Xu (University of Chinese Academy of Sciences) ; März, Winfried (Medical University of Graz) ; Gudnason, Vilmundur (University of Iceland) ; Tardif, Jean-Claude (Université de Montréal) ; Lettre, Guillaume (Université de Montréal) ; Hart, Leen M.'t (Amsterdam Public Health Research Institute) ; Elders, Petra J. M. (Amsterdam Public Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Kumari, Meena (University of Essex) ; Kivimaki, Mika (University College London) ; van der Harst, Pim (Utrecht University) ; Spector, Tim D. (King's College London) ; Loos, Ruth J. F. (Icahn School of Medicine at Mount Sinai) ; Province, Michael A. (Washington University School of Medicine) ; Parra, Esteban J. (University of Toronto at Mississauga) ; Cruz, Miguel (Centro Medico Nacional Siglo XXI) ; Psaty, Bruce M. (University of Washington) ; Brandslund, Ivan (University of Southern Denmark) ; Pramstaller, Peter P. (Affiliated Institute of the University of Lübeck) ; Rotimi, Charles N. (Center for Research On Genomics and Global Health) ; Christensen, Kaare (University of Southern Denmark) ; Ripatti, Samuli (Broad Institute of MIT and Harvard) ; Widén, Elisabeth (University of Helsinki) ; Hakonarson, Hakon (The University of Pennsylvania Perelman School of Medicine) ; Grant, Struan F. A. (Children's Hospital of Philadelphia (Pennsilvània)) ; Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ; de Graaf, Jacqueline (Radboud University Medical Center) ; Loeffler, Markus (University of Leipzig) ; Kronenberg, Florian (German Chronic Kidney Disease Study (Alemanya)) ; Gu, Dongfeng (Southern University of Science and Technology) ; Erdmann, Jeanette (University Heart Center Lübeck) ; Schunkert, Heribert (Partner Site Munich Heart Alliance) ; Franks, Paul W. (Lund University Diabetes Centre) ; Linneberg, Allan (University of Copenhagen) ; Jukema, J. Wouter (Netherlands Heart Institute) ; Khera, Amit V. (Verve Therapeutics) ; Männikkö, Minna (Northern Finland Birth Cohorts) ; Jarvelin, Marjo-Riitta (University of Oulu) ; Kutalik, Zoltan (Swiss Institute of Bioinformatics) ; Francesco, Cucca (University of Sassari) ; Mook-Kanamori, Dennis O. (Leiden University Medical Center) ; van Dijk, Ko Willems (Leiden University Medical Center) ; Watkins, Hugh (University of Oxford) ; Strachan, David P. (University of London) ; Grarup, Niels (University of Copenhagen) ; Sever, Peter (Imperial College London) ; Poulter, Neil (Imperial College London) ; Chuang, Lee-Ming (National Taiwan University Hospital (Taipei, Taiwan)) ; Rotter, Jerome I. (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Dantoft, Thomas M. (Bispebjerg and Frederiksberg Hospital) ; Karpe, Fredrik (NIHR Oxford Biomedical Research Centre) ; Neville, Matt J. (NIHR Oxford Biomedical Research Centre) ; Timpson, Nicholas J. (University of Bristol) ; Cheng, Ching-Yu (Duke-NUS Medical School) ; Wong, Tien-Yin (Duke-NUS Medical School) ; Khor, Chiea Chuen (Genome Institute of Singapore) ; Li, Hengtong (Singapore Eye Research Institute) ; Sabanayagam, Charumathi (Duke-NUS Medical School) ; Peters, Annette (German Center for Diabetes Research (DZD)) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Hattersley, Andrew T. (University of Exeter) ; Pedersen, Nancy L. (Karolinska Institutet (Estocolm, Suècia)) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia)) ; Boomsma, Dorret I. (Amsterdam Public Health Research Institute) ; Willemsen, Allegonda H. M. (Amsterdam Public Health Research Institute) ; Cupples, LAdrienne (US National Institutes of Health) ; van Meurs, Joyce B. J. (University Medical Center Rotterdam) ; Ghanbari, Mohsen (Mashhad University of Medical Sciences) ; Gordon-Larsen, Penny (University of North Carolina) ; Huang, Wei (Chinese National Human Genome Center at Shanghai) ; Kim, Young Jin (National Institute of Health) ; Tabara, Yasuharu (Kyoto University Graduate School of Medicine) ; Wareham, Nicholas J. (University of Cambridge School of Clinical Medicine) ; Langenberg, Claudia (Berlin Institute of Health at Charité - Universitätsmedizin) ; Zeggini, Eleftheria (Helmholtz Zentrum München - German Research Center for Environmental Health) ; Kuusisto, Johanna (University of Eastern Finland and Kuopio University Hospital) ; Laakso, Markku (University of Eastern Finland and Kuopio University Hospital) ; Ingelsson, Erik (Stanford University) ; Abecasis, Goncalo (Regeneron Pharmaceuticals) ; Chambers, John C. (Imperial College London) ; Kooner, Jaspal S. (Imperial College London) ; de Vries, Paul S. (The University of Texas Health Science Center at Houston) ; Morrison, Alanna C. (The University of Texas Health Science Center at Houston) ; Hazelhurst, Scott (University of the Witwatersrand) ; Ramsay, Michèle (University of the Witwatersrand) ; North, Kari E. (University of North Carolina) ; Daviglus, Martha (University of Illinois College of Medicine) ; Kraft, Peter (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Martin, Nicholas G. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Whitfield, John B. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Abbas, Shahid (Faisalabad Institute of Cardiology) ; Saleheen, Danish (Columbia University Irving Medical Center) ; Walters, Robin G. (University of Oxford) ; Holmes, Michael V. (Oxford University Hospitals) ; Black, Corri (University of Aberdeen) ; Smith, Blair H. (University of Dundee) ; Baras, Aris (Regeneron Pharmaceuticals) ; Justice, Anne E. (Geisinger Health) ; Buring, Julie E. (Harvard Medical School) ; Ridker, Paul M. (Harvard Medical School) ; Chasman, Daniel I. (Harvard Medical School) ; Kooperberg, Charles (Fred Hutchinson Cancer Center) ; Tamiya, Gen (Tohoku University) ; Yamamoto, Masayuki (Tohoku University) ; van Heel, David A (Queen Mary University of London) ; Trembath, Richard C. (King's College London) ; Wei, Wei-Qi (Vanderbilt University Medical Center) ; Jarvik, Gail P. (University of Washington) ; Namjou, Bahram (Cincinnati Children's Hospital Medical Center) ; Hayes, M. Geoffrey (Northwestern University) ; Ritchie, Marylyn D. (University of Pennsylvania) ; Jousilahti, Pekka (Finnish Institute for Health and Welfare) ; Salomaa, Veikko (Finnish Institute for Health and Welfare) ; Hveem, Kristian (St Olav's University Hospital) ; Åsvold, Bjørn Olav (St Olav's University Hospital) ; Kubo, Michiaki (RIKEN Center for Integrative Medical Sciences) ; Kamatani, Yoichiro (The University of Tokyo) ; Okada, Yukinori (The University of Tokyo) ; Murakami, Yoshinori (The University of Tokyo) ; Kim, Bong-Jo (National Institute of Health) ; Thorsteinsdottir, Unnur (University of Iceland) ; Stefansson, Kari (The University of Manchester) ; Zhang, Jifeng (University of Michigan) ; Chen, YEugene (University of Michigan) ; Ho, Yuk-Lam (VA Boston Healthcare System) ; Lynch, Julie A. (University of Massachusetts) ; Rader, Daniel J. (University of Pennsylvania) ; Tsao, Philip S. (Stanford University School of Medicine) ; Chang, Kyong-Mi (University of Pennsylvania Perelman School of Medicine) ; Cho, Kelly (Brigham Women's Hospital) ; O'Donnell, Christopher J. (Brigham Women's Hospital) ; Gaziano, John M. (Brigham Women's Hospital) ; Wilson, Peter W. F. (Emory University School of Medicine) ; Frayling, Timothy M. (University of Exeter Medical School) ; Hirschhorn, Joel N. (Harvard Medical School) ; Kathiresan, Sekar (Harvard Medical School) ; Mohlke, Karen L. (University of North Carolina) ; Sun, Yan V. (Atlanta VA Health Care System) ; Morris, Andrew P. (The University of Manchester) ; Boehnke, Michael (University of Michigan) ; Brown, Christopher D. (University of Pennsylvania) ; Natarajan, Pradeep (Massachusetts General Hospital) ; Deloukas, Panos (King Abdulaziz University) ; Willer, Cristen J. (University of Michigan) ; Assimes, Themistocles (Stanford University School of Medicine. Cardiovascular Institute) ; Peloso, Gina M (Boston University School of Public Health. Department of Biostatistics) ; Universitat Autònoma de Barcelona
Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery. [...]
2022 - 10.1186/s13059-022-02837-1
Genome biology, Vol. 23 (december 2022)  
2.
58 p, 1.4 MB The power of genetic diversity in genome-wide association studies of lipids / Graham, Sarah E. (University of Michigan. Department of Internal Medicine) ; Chang, Kyong-Mi (Corporal Michael J. Crescenz VA Medical Center) ; Cho, Kelly (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; O'Donnell, Christopher J. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Gaziano, John M. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Wilson, Peter (Emory University School of Medicine) ; Rotimi, Charles (Center for Research on Genomics and Global Health. National Human Genome Research Institute. National Institutes of Health) ; Hazelhurst, Scott (University of the Witwatersrand. School of Electrical and Information Engineering) ; Ramsay, Michele (University of the Witwatersrand) ; Trembath, Richard C. (King's College London) ; van Heel, David A (Queen Mary University of London) ; Tamiya, Gen (Tohoku Medical Megabank Organization. Tohoku University) ; Yamamoto, Masayuki (Tohoku Medical Megabank Organization. Tohoku University) ; Kim, Bong-Jo (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Mohlke, Karen L (Department of Genetics. University of North Carolina) ; Frayling, Timothy M. (Genetics of Complex Traits. University of Exeter Medical School. University of Exeter) ; Hirschhorn, Joel N. (Departments of Pediatrics and Genetics. Harvard Medical School) ; Kathiresan, Sekar (Center for Genomic Medicine. Department of Medicine. Massachusetts General Hospital) ; Boehnke, Michael (Department of Biostatistics and Center for Statistics Genetics. University of Michigan) ; Natarajan, Pradeep (Cardiovascular Research Center and Center for Genomic Medicine. Massachusetts General Hospital) ; Peloso, Gina M (Department of Biostatistics. Boston University School of Public Health) ; Brown, Christopher D. (Department of Genetics. Perelman School of Medicine. University of Pennsylvania) ; Morris, Andrew P. (University College London. Centre for Adolescent Rheumatology Versus Arthritis) ; Assimes, Themistocles (Stanford University School of Medicine. Cardiovascular Institute) ; Deloukas, Panos (King Abdulaziz University) ; Sun, Yan V. (Atlanta VA Health Care System) ; Willer, Cristen J. (Department of Human Genetics. University of Michigan) ; Clarke, Shoa L. (Department of Medicine. Division of Cardiovascular Medicine. Stanford University School of Medicine) ; Wu, Kuan-Han H. (Department of Computational Medicine and Bioinformatics. University of Michigan) ; Kanoni, Stavroula (Queen Mary University of London) ; Zajac, Greg J. M. (University of Michigan) ; Ramdas, Shweta (University of Pennsylvania) ; Surakka, Ida (University of Michigan) ; Ntalla, Ioanna (Queen Mary University of London) ; Vedantam, Sailaja (Medical and Population Genetics. Broad Institute) ; Winkler, Thomas W. (Department of Genetic Epidemiology. University of Regensburg) ; Locke, Adam E. (McDonnell Genome Institute and Department of Medicine. Washington University) ; Marouli, Eirini (Queen Mary University of London) ; Hwang, Mi Yeong (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Han, Sohee (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Narita, Akira (Tohoku Medical Megabank Organization. Tohoku University) ; Choudhury, Ananyo (Sydney Brenner Institute for Molecular Bioscience. Faculty of Health Sciences. University of the Witwatersrand) ; Bentley, Amy R (Center for Research on Genomics and Global Health. National Human Genome Research Institute. National Institutes of Health) ; Ekoru, Kenneth (Center for Research on Genomics and Global Health. National Human Genome Research Institute. National Institutes of Health) ; Verma, Anurag (Department of Genetics. Perelman School of Medicine. University of Pennsylvania) ; Trivedi, Bhavi (Blizard Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; Martin, Hilary C. (Wellcome Trust Sanger Institute (Regne Unit)) ; Hunt, Karen A. (Blizard Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; Hui, Qin (Atlanta VA Health Care System) ; Klarin, Derek (Program in Medical and Population Genetics. Broad Institute of MIT and Harvard) ; Zhu, Xiang (Stanford University. Department of Statistics) ; Thorleifsson, Gudmar (deCODE genetics/Amgen) ; Helgadottir, Anna (deCODE genetics/Amgen) ; Gudbjartsson, Daniel F. (School of Engineering and Natural Sciences. University of Iceland) ; Holm, Hilma (deCODE genetics/Amgen) ; Olafsson, Isleifur (Department of Clinical Biochemistry. Landspitali-National University Hospital of Iceland) ; Akiyama, Masato (Department of Ophthalmology. Graduate School of Medical Sciences. Kyushu University) ; Sakaue, Saori (Department of Allergy and Rheumatology. Graduate School of Medicine. The University of Tokyo) ; Terao, Chikashi (Laboratory for Statistical and Translational Genetics. RIKEN Center for Integrative Medical Sciences) ; Kanai, Masahiro (Harvard Medical School. Department of Biomedical Informatics) ; Zhou, Wei (Broad Institute of MIT and Harvard) ; Brumpton, Ben M. (St Olavs Hospital. Trondheim University Hospital) ; Rasheed, Humaira (MRC Integrative Epidemiology Unit. University of Bristol) ; Ruotsalainen, Sanni E. (University of Helsinki) ; Havulinna, Aki S. (Finnish Institute for Health and Welfare) ; Veturi, Yogasudha (University of Pennsylvania. Perelman School of Medicine) ; Feng, QiPing (Vanderbilt University Medical Center) ; Rosenthal, Elisabeth A. (University of Washington. Department of Medicine) ; Lingren, Todd (Cincinnati Children's Hospital Medical Center) ; Pacheco, Jennifer Allen (Center for Genetic Medicine. Northwestern University) ; Pendergrass, Sarah A. (Genentech) ; Haessler, Jeffrey (Fred Hutchinson Cancer Research Center. Division of Public Health Sciences) ; Giulianini, Franco (Division of Preventive Medicine. Brigham and Women's Hospital) ; Bradford, Yuki (Department of Genetics. Institute for Biomedical Informatics. Perelman School of Medicine. University of Pennsylvania) ; Miller, Jason E. (Department of Genetics. Institute for Biomedical Informatics. Perelman School of Medicine. University of Pennsylvania) ; Campbell, Archie (University of Edinburgh) ; Lin, Kuang (University of Oxford. Nuffield Department of Population Health) ; Millwood, Iona Y. (University of Oxford. Nuffield Department of Population Health) ; Hindy, George (Qatar University College of Medicine) ; Rasheed, Asif (Center for Non-Communicable Diseases) ; Faul, Jessica D. (University of Michigan. Institute for Social Research) ; Zhao, Wei (University of Michigan. School of Public Health) ; Weir, David R (University of Michigan. Institute for Social Research) ; Turman, Constance (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Huang, Hongyan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Graff, Mariaelisa (University of North Carolina. Department of Epidemiology) ; Mahajan, Anubha (University of Oxford. Wellcome Centre for Human Genetics) ; Brown, Michael R. (The University of Texas Health Science Center at Houston) ; Zhang, Weihua (Imperial College Healthcare NHS Trust) ; Yu, Ketian (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Schmidt, Ellen M. (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Pandit, Anita (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Gustafsson, Stefan (Department of Medical Sciences. Molecular Epidemiology and Science for Life Laboratory. Uppsala University) ; Yin, Xianyong (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Luan, Jian'an (MRC Epidemiology Unit. University of Cambridge School of Clinical Medicine) ; Zhao, Jing-Hua (Cardiovascular Epidemiology Unit. Department of Public Health and Primary Care. University of Cambridge Strangeways Research Laboratory) ; Matsuda, Fumihiko (Center for Genomic Medicine. Kyoto University Graduate School of Medicine) ; Jang, Hye-Mi (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Yoon, Kyungheon (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Medina-Gomez, Carolina (Department of Epidemiology. Erasmus MC. University Medical Center Rotterdam) ; Pitsillides, Achilleas (Department of Biostatistics. Boston University School of Public Health) ; Hottenga, Jouke Jan (Amsterdam Public Health. VU Medical Center Amsterdam) ; Willemsen, Gonneke (Amsterdam Public Health Research Institute. VU Medical Center Amsterdam) ; Wood, Andrew R. (Genetics of Complex Traits. University of Exeter Medical School. University of Exeter) ; Ji, Yingji (Genetics of Complex Traits. University of Exeter Medical School. University of Exeter) ; Gao, Zishan (Institute of Epidemiology. Helmholtz Zentrum München. German Research Center for Environmental Health) ; Haworth, Simon (Bristol Dental School. University of Bristol) ; Mitchell, Ruth E. (Population Health Sciences. Bristol Medical School. University of Bristol) ; Chai, Jin-Fang (Saw Swee Hock School of Public Health. National University of Singapore and National University Health System) ; Aadahl, Mette (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Yao, Jie (The Institute for Translational Genomics and Population Sciences. Department of Pediatrics. Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Manichaikul, Ani (University of Virginia. Center for Public Health Genomics) ; Warren, Helen R. (NIHR Barts Cardiovascular Biomedical Research Centre. Barts and The London School of Medicine and Dentistry. Queen Mary University of London) ; Ramírez, Julia (William Harvey Research Institute. Barts and The London School of Medicine and Dentistry. John Vane Science Centre. Queen Mary University of London) ; Bork-Jensen, Jette (University of Copenhagen) ; Kårhus, Line L. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Goel, Anuj (University of Oxford. Radcliffe Department of Medicine) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Noordam, Raymond (Leiden University Medical Center) ; Sidore, Carlo (Institute for Genetic and Biomedical Research. Italian National Council of Research (IRGB CNR)) ; Fiorillo, Edoardo (Institute for Genetic and Biomedical Research. Italian National Council of Research (IRGB CNR)) ; McDaid, Aaron F. (Swiss Institute of Bioinformatics) ; Marques-Vidal, Pedro (Lausanne University Hospital) ; Wielscher, Matthias (Department of Epidemiology and Biostatistics. MRC-PHE Centre for Environment and Health. School of Public Health. Imperial College London) ; Trompet, Stella (Leiden University Medical Center) ; Sattar, Naveed (BHF Glasgow Cardiovascular Research Centre. Faculty of Medicine) ; Møllehave, Line T. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Thuesen, Betina H. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Munz, Matthias (Department of Periodontology and Synoptic Dentistry. Berlin Institute of Health. Institute for Dental and Craniofacial Sciences) ; Zeng, Lingyao (Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK). Partner site Munich Heart Alliance) ; Huang, Jianfeng (Chinese Academy of Medical Sciences) ; Yang, Bin (Chinese Academy of Medical Sciences) ; Poveda, Alaitz (Lund University Diabetes Centre) ; Kurbasic, Azra (Lund University Diabetes Centre) ; Lamina, Claudia (German Chronic Kidney Disease Study) ; Forer, Lukas (German Chronic Kidney Disease Study) ; Scholz, Markus (LIFE Research Centre for Civilization Diseases. University of Leipzig) ; Galesloot, Tessel E (Radboud University Medical Center. Radboud Institute for Health Sciences) ; Bradfield, Jonathan Paul (Quantinuum Research) ; Daw, E. Warwick (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Zmuda, Joseph M (Department of Epidemiology. University of Pittsburgh) ; Mitchell, Jonathan S. (Institute for Biomedicine. Eurac Research. Affiliated Institute of the University of Lübeck) ; Fuchsberger, Christian (Institute for Biomedicine. Eurac Research. Affiliated Institute of the University of Lübeck) ; Christensen, Henry (Department of Clinical Biochemistry. Lillebaelt Hospital) ; Brody, Jennifer A. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Feitosa, Mary (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Wojczynski, Mary K. (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Preuss, Michael (The Charles Bronfman Institute for Personalized Medicine. Icahn School of Medicine at Mount Sinai) ; Mangino, Massimo (NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust) ; Christofidou, Paraskevi (Department of Twin Research and Genetic Epidemiology. King's College London) ; Verweij, Niek (Department of Cardiology. University Medical Center Groningen. University of Groningen) ; Benjamins, Jan W (Department of Cardiology. University Medical Center Groningen. University of Groningen) ; Engmann, Jorgen (Department of Epidemiology and Public Health. University College London) ; Kember, Rachel L. (Department of Psychiatry. University of Pennsylvania) ; Slieker, Roderick C. (Department of Cell and Chemical Biology. Leiden University Medical Center) ; Lo, Ken S. (Montreal Heart Institute) ; Zilhao, Nuno R. (Icelandic Heart Association) ; Le, Phuong (Department of Anthropology. University of Toronto at Mississauga) ; Kleber, Marcus E. (Synlab MVZ Humangenetik Mannheim) ; Delgado, Graciela E. (University of Heidelberg. Vth Department of Medicine) ; Huo, Shsofeng (Shanghai Institute of Nutrition and Health. University of Chinese Academy of Sciences. Chinese Academy of Sciences) ; Ikeda, Daisuke D. (Biomedical Technology Research Center. Tokushima Research Institute. Otsuka Pharmaceutical) ; Iha, Hiroyuki (Biomedical Technology Research Center. Tokushima Research Institute. Otsuka Pharmaceutical) ; Yang, Jian (Department of Neurological Sciences. Rush University Medical Center) ; Liu, Jun (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Leonard, Hampton L. (Data Tecnica International) ; Marten, Jonathan (MRC Human Genetics Unit. Institute of Genetics and Cancer. University of Edinburgh. Western General Hospital) ; Schmidt, Börge (Institute for Medical Informatics. Biometrie and Epidemiology. University of Duisburg-Essen) ; Arendt, Marina (Department of Computer Science. University of Applied Sciences and Arts Dortmund) ; Smyth, Laura J. (Centre for Public Health. Queen's University of Belfast) ; Cañadas-Garre, Marisa (Centre for Public Health. Queen's University of Belfast) ; Wang, Chaolong (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Nakatochi, Masahiro (Public Health Informatics Unit. Department of Integrated Health Sciences. Nagoya University Graduate School of Medicine) ; Wong, Andrew (MRC Unit for Lifelong Health and Ageing at UCL) ; Hutri-Kähönen, Nina (Department of Pediatrics. Faculty of Medicine and Health Technology. Tampere University) ; Sim, Xueling (Saw Swee Hock School of Public Health. National University of Singapore and National University Health System) ; Xia, Rui (Brown Foundation Institute of Molecular Medicine. McGovern Medical School. University of Texas Health Science Center at Houston) ; Huerta-Chagoya, Alicia (Departamento de Medicina Genómica y Toxicología Ambiental. Instituto de Investigaciones Biomédicas. UNAM. Ciudad de Mexico) ; Fernandez-Lopez, Juan Carlos (Departamento de Genómica Computacional. Instituto Nacional de Medicina Genómica. Ciudad de Mexico) ; Lyssenko, Valeriya (Lund University Diabetes Center. Lund University) ; Ahmed, Meraj (Genomic Research on Complex Diseases (GRC Group). CSIR-Centre for Cellular and Molecular Biology) ; Jackson, Anne U. (Department of Biostatistics and Center for Statistics Genetics. University of Michigan) ; Irvin, Marguerite R. (Epidemiology. School of Public Health. University of Alabama at Birmingham) ; Oldmeadow, Christopher (Hunter Medical Research Institute) ; Kim, Han-Na (Department of Clinical Research Design and Evaluation. SAIHST. Sungkyunkwan University) ; Ryu, Seungho (Sungkyunkwan University School of Medicine) ; Timmers, Paul R. H. J. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Arbeeva, Liubov (University of North Carolina. Thurston Arthritis Research Center) ; Dorajoo, Rajkumar (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Lange, Leslie A. (Division of Biomedical Informatics and Personalized Medicine. Department of Medicine. Anschutz Medical Campus. University of Colorado. Denver) ; Chai, Xiaoran (Department of Ophthalmology. National University of Singapore and National University Health System) ; Prasad, Gauri (Academy of Scientific and Innovative Research. CSIR-Institute of Genomics and Integrative Biology Campus) ; Lorés-Motta, Laura (Departments of Ophthalmology and Human Genetics. Radboud University Nijmegen Medical Center) ; Pauper, Marc (Departments of Ophthalmology and Human Genetics. Radboud University Nijmegen Medical Center) ; Long, Jirong (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; Li, Xiaohui (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Theusch, Elisabeth (Department of Pediatrics. University of California. San Francisco) ; Takeuchi, Fumihiko (National Center for Global Health and Medicine) ; Spracklen, Cassandra N. (Department of Biostatistics and Epidemiology. University of Massachusetts-Amherst) ; Loukola, Anu (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Bollepalli, Sailalitha (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Warner, Sophie C. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Wang, Ya Xing (Beijing Tongren Eye Center. Beijing Tongren Hospital. Capital Medical University) ; Wei, Wen B. (Beijing Tongren Eye Center. Beijing Tongren Hospital. Capital Medical University) ; Nutile, Teresa (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR) ; Ruggiero, Daniela (IRCCS Neuromed. Pozzilli) ; Sung, Yun Ju (Department of Psychiatry. Washington University) ; Hung, Yi-Jen (Division of Endocrinology and Metabolism. Tri-Service General Hospital Songshan Branch) ; Chen, Shufeng (Chinese Academy of Medical Sciences) ; Liu, Fangchao (Chinese Academy of Medical Sciences) ; Yang, Jingyun (Department of Neurological Sciences. Rush University Medical Center) ; Kentistou, Katherine A. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Gorski, Mathias (Department of Nephrology. University Hospital Regensburg) ; Brumat, Marco (Department of Medicine. Surgery and Health Sciences. University of Trieste) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Bielak, Lawrence F. (Department of Epidemiology. School of Public Health. University of Michigan) ; Smith, Jennifer A. (Department of Epidemiology. School of Public Health. University of Michigan) ; Hebbar, Prashantha (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Farmaki, Aliki-Eleni (Department of Population Science and Experimental Medicine. University College London) ; Hofer, Edith (Institute for Medical Informatics. Statistics and Documentation. Medical University of Graz) ; Lin, Maoxuan (Department of Bioinformatics and Genomics. University of North Carolina at Charlotte) ; Xue, Chao (Department of Internal Medicine. Division of Cardiology. University of Michigan) ; Zhang, Jifeng (Department of Internal Medicine. Division of Cardiology. University of Michigan) ; Concas, Maria Pina (Institute for Maternal and Child Health. IRCCS Burlo Garofolo) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research. National Research Council of Italy. UOS of Sassari) ; van der Most, Peter J (Department of Epidemiology. University Medical Center Groningen. University of Groningen) ; Pitkänen, Niina (Centre for Population Health Research. University of Turku and Turku University Hospital) ; Cade, Brian E (Division of Sleep Medicine. Harvard Medical School) ; Lee, Jiwon (Sleep Medicine and Circadian Disorders. Brigham and Women's Hospital) ; van der Laan, Sander W (University Medical Center Utrecht) ; Chitrala, Kumaraswamy Naidu (Laboratory of Epidemiology and Population Science. National Institute on Aging Intramural Research Program. NIH Biomedical Research Center. NIA) ; Weiss, Stefan (University Medicine Greifswald) ; Zimmermann, Martina E (University of Regensburg. Department of Genetic Epidemiology) ; Lee, Jong Young (Oneomics) ; Choi, Hyeok Sun (Department of Biomedical Science. Hallym University) ; Nethander, Maria (Bioinformatics Core Facility. Sahlgrenska Academy. University of Gothenburg) ; Freitag-Wolf, Sandra (Institute of Medical Informatics and Statistics. Kiel University) ; Southam, Lorraine (Wellcome Trust Sanger Institute (Regne Unit)) ; Rayner, Nigel W. (Oxford Centre for Diabetes Endocrinology and Metabolism) ; Wang, Carol A (School of Medicine and Public Health. College of Health. Medicine and Wellbeing. University of Newcastle) ; Lin, Shih Yi (School of Medicine. National Defense Medical Center) ; Wang, Jun-Sing (Department of Medicine. School of Medicine. National Yang-Ming University) ; Couture, Christian (Department of Kinesiology. Université Laval) ; Lyytikäinen, Leo-Pekka (Department of Clinical Chemistry. Finnish Cardiovascular Research Center-Tampere. Faculty of Medicine and Health Technology. Tampere University) ; Nikus, Kjell (Department of Cardiology. Finnish Cardiovascular Research Center-Tampere. Faculty of Medicine and Health Technology. Tampere University) ; Cuellar-Partida, Gabriel (University of Queensland Diamantina Institute. Translational Research Institute) ; Vestergaard, Henrik (Department of Medicine. Bornholms Hospital) ; Hildalgo, Bertha (School of Public Health. University of Alabama at Birmingham) ; Giannakopoulou, Olga (William Harvey Research Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; Cai, Qiuyin (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; Obura, Morgan O. (Amsterdam UMC. Department of Epidemiology and Biostatistics. Amsterdam Public Health Research Institute) ; van Setten, Jessica (University Medical Center Utrecht) ; Li, Xiaoyin (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Schwander, Karen (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Terzikhan, Natalie (Department of Epidemiology. Erasmus MC. University Medical Center Rotterdam) ; Shin, Jae Hun (Department of Biomedical Science. Hallym University) ; Jackson, Rebecca D. (Division of Endocrinology. Ohio State University) ; Reiner, Alewxander P. (Department of Epidemiology. University of Washington) ; Martin, Lisa W. (School of Medicine and Health Sciences. George Washington University) ; Chen, Zhengming (Medical Research Council Population Health Research Unit. Nuffield Department of Population Health. University of Oxford) ; Li, Liming (Peking University Health Science Center) ; Highland, Heather M. (Department of Epidemiology. University of North Carolina) ; Young, Kristin L. (Department of Epidemiology. University of North Carolina) ; Kawaguchi, Takahisa (Center for Genomic Medicine. Kyoto University Graduate School of Medicine) ; Thiery, Joachim (Institute for Laboratory Medicine. University Hospital Leipzig) ; Bis, Joshua C (Cardiovascular Health Research Unit. Department of Medicine. University of Washington) ; Nadkarni, Girish N. (The Charles Bronfman Institute for Personalized Medicine. Icahn School of Medicine at Mount Sinai) ; Launer, Lenore Joy (Laboratory of Epidemiology and Population Sciences. National Institute on Aging. NIH) ; Li, Huaixing (Shanghai Institute of Nutrition and Health. University of Chinese Academy of Sciences. Chinese Academy of Sciences) ; Nalls, Mike A. (Data Tecnica International) ; Raitakari, Olli T. (Department of Clinical Physiology and Nuclear Medicine. Turku University Hospital) ; Ichihara, Sahoko (Department of Environmental and Preventive Medicine. Jichi Medical University School of Medicine) ; Wild, Sarah (Centre for Population Health Sciences. Usher Institute. University of Edinburgh) ; Nelson, Christopher P. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Campbell, Harry (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Jäger, Susanne (German Center for Diabetes Research (DZD)) ; Nabika, Toru (Department of Functional Pathology. Shimane University School of Medicine) ; Al-Mulla, Fahd (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Niinikoski, Harri (Department of Physiology. University of Turku) ; Braund, Peter S. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Kolcic, Ivana (Faculty of Medicine. University of Split) ; Kovacs, Peter (Medical Department III-Endocrinology. Nephrology. Rheumatology. University of Leipzig Medical Center) ; Giardoglou, Tota (Department of Nutrition-Dietetics. Harokopio University. Eleftheriou Venizelou) ; Katsuya, Tomohiro (Department of Geriatric and General Medicine. Osaka University Graduate School of Medicine) ; Bhatti, Konain Fatima (William Harvey Research Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; de Kleijn, Dominique (University Medical Center Utrecht) ; de Borst, Gert J. (University Medical Center Utrecht) ; Kim, Eung Kweon (Corneal Dystrophy Research Institute. Department of Ophthalmology. Yonsei University College of Medicine) ; Adams, Hieab H. H. (Department of Radiology and Nuclear Medicine. Erasmus MC. University Medical Center Rotterdam) ; Ikram, M. Arfan (Erasmus University Medical Center. Department of Epidemiology) ; Zhu, Xiaofeng (Case Western Reserve University. Department of Population and Quantitative Health Sciences) ; Asselbergs, Folkert W (University Medical Center Utrecht) ; Kraaijeveld, Adriaan O. (University Medical Center Utrecht) ; Beulens, Joline W. J. (University Medical Center Utrecht) ; Shu, Xiao-Ou (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; Rallidis, Loukianos S. (Kapodistrian University of Athens) ; Pedersen, Oluf (University of Copenhagen) ; Hansen, Torben (University of Copenhagen) ; Mitchell, Paul (University of Sydney) ; Hewitt, Alex W. (University of Melbourne) ; Kähönen, Mika (Tampere University) ; Pérusse, Louis (Institute of Nutrition and Functional Foods (INAF). Université Laval) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Tönjes, Anke (Medical Department III-Endocrinology. Nephrology. Rheumatology. University of Leipzig Medical Center) ; Chen, Yii Der Ida (The Institute for Translational Genomics and Population Sciences. Department of Pediatrics. Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Pennell, Craig E. (School of Medicine and Public Health. College of Health. Medicine and Wellbeing. University of Newcastle) ; Mori, Trevor A (Medical School. Faculty of Health and Medical Sciences. University of Western Australia) ; Lieb, Wolfgang (Institute of Epidemiology. Kiel University) ; Franke, Andre (Christian-Albrechts-University of Kiel. Institute of Clinical Molecular Biology) ; Ohlsson, Claes (Department of Drug Treatment. Sahlgrenska University Hospital) ; Mellström, Dan (Geriatric Medicine. Institute of Medicine. Sahlgrenska Academy. University of Gothenburg) ; Cho, Yoon Shin (Department of Biomedical Science. Hallym University) ; Lee, Hyejin (Department of Internal Medicine. Ewha Womans University School of Medicine) ; Yuan, Jan-Min (Department of Epidemiology. Graduate School of Public Health. University of Pittsburgh) ; Koh, Woon-Puay (Singapore Institute for Clinical Sciences. Agency for Science Technology and Research (A*STAR)) ; Rhee, Sang Youl (Department of Endocrinology and Metabolism. Kyung Hee University School of Medicine) ; Woo, Jeong-Taek (Department of Endocrinology and Metabolism. Kyung Hee University School of Medicine) ; Heid, Iris M. (Department of Genetic Epidemiology. University of Regensburg) ; Stark, Klaus J. (Department of Genetic Epidemiology. University of Regensburg) ; Völzke, Henry (Institute for Community Medicine. University Medicine Greifswald) ; Homuth, Georg (Department of Functional Genomics. Interfaculty Institute for Genetics and Functional Genomics. University of Greifswald and University Medicine Greifswald) ; Evans, Michele K. (Laboratory of Epidemiology and Population Science. National Institute on Aging Intramural Research Program. NIH Biomedical Research Center) ; Zonderman, Alan B (Laboratory of Epidemiology and Population Science. National Institute on Aging Intramural Research Program. NIH Biomedical Research Center) ; Polasek, Ozren (Faculty of Medicine. University of Split) ; Pasterkamp, Gerard (University Medical Center Utrecht) ; Hoefer, Imo E. (University Medical Center Utrecht) ; Redline, Susan (Harvard Medical School) ; Pahkala, Katja (University of Turku) ; Oldehinkel, Albertine J (Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE). University of Groningen. University Medical Center Groningen) ; Snieder, Harold (Department of Epidemiology. University Medical Center Groningen. University of Groningen) ; Biino, Ginevra (National Research Council of Italy. Institute of Molecular Genetics) ; Schmidt, Reinhold (Department of Neurology. Clinical Division of Neurogeriatrics. Medical University of Graz) ; Schmidt, Helena (Medical University Graz) ; Chen, Y. Eugene (Department of Internal Medicine. Division of Cardiology. University of Michigan) ; Bandinelli, Stefania (Local Health Unit Toscana Centro) ; Dedoussis, George (Harokopio University of Athens) ; Thanaraj, Thangavel Alphonse (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Kardia, Sharon L. R. (Department of Epidemiology. School of Public Health. University of Michigan) ; Kato, Norihiro (National Center for Global Health and Medicine) ; Schulze, Matthias B. (Institute of Nutritional Science. University of Potsdam) ; Girotto, Giorgia (Institute for Maternal and Child Health IRCCS "Burlo Garofolo") ; Jung, Bettina (Department of Nephrology. University Hospital Regensburg) ; Böger, Carsten A. (KfH Kidney Center Traunstein) ; Joshi, Peter K. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Bennett, David A. (Department of Neurological Sciences. Rush University Medical Center) ; De Jager, Philip L. (Program in Medical and Population Genetics. Broad Institute) ; Lu, Xiangfeng (Chinese Academy of Medical Sciences) ; Mamakou, Vasiliki (Dromokaiteio Psychiatric Hospital) ; Brown, Morris (Clinical Pharmacology. William Harvey Research Institute. Queen Mary University of London) ; Caulfield, Mark (Queen Mary University of London. William Harvey Research Institute) ; Munroe, Patricia B. (Queen Mary University of London. Barts and The London School of Medicine and Dentistry) ; Guo, Xiuqing (The Institute for Translational Genomics and Population Sciences. Department of Pediatrics. Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Ciullo, Marina (IRCCS Neuromed. Pozzilli) ; Jonas, Jost B. (Institute of Molecular and Clinical Ophthalmology Basel) ; Samani, Nilesh J. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Kaprio, Jaakko (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Pajukanta, Päivi (University of California. David Geffen School of Medicine at UCLA.) ; Adair, Linda S (Carolina Population Center. University of North Carolina) ; Bechayda, Sonny Augustin (Department of Anthropology. Sociology. and History. University of San Carlos) ; de Silva, H. Janaka (Department of Medicine. Faculty of Medicine. University of Kelaniya) ; Wickremasinghe, Ananda R. (Department of Public Health. Faculty of Medicine. University of Kelaniya) ; Krauss, Ronald M. (Departments of Pediatrics and Medicine. University of California. San Francisco) ; Wu, Jer-Yuarn (Institute of Biomedical Sciences. Academia Sinica) ; Zheng, Wei (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; den Hollander, Anneke I. (Departments of Ophthalmology and Human Genetics. Radboud University Nijmegen Medical Center) ; Bharadwaj, Dwaipayan (Systems Genomics Laboratory. School of Biotechnology. Jawaharlal Nehru University) ; Correa, Adolfo (University of Mississippi Medical Center) ; Wilson, James G. (University of Mississippi Medical Center) ; Lind, Lars (Uppsala University. Department of Medical Sciences) ; Heng, Chew-Kiat (Khoo Teck Puat-National University Children's Medical Institute. National University Health System) ; Nelson, Amanda E. (Department of Medicine. University of North Carolina) ; Golightly, Yvonne M. (Division of Physical Therapy. University of North Carolina) ; Wilson, James F. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Penninx, Brenda WJH (Amsterdam Public Health Research Institute. VU Medical Center Amsterdam) ; Kim, Hyung-Lae (Department of Biochemistry. College of Medicine. Ewha Womans University) ; Attia, John (University of Newcastle. Faculty of Health and Medicine) ; Scott, Rodney J. (University of Newcastle. Faculty of Health and Medicine) ; Rao, D. C. (Washington University School of Medicine) ; Arnett, Donna K. (University of Kentucky. College of Public Health) ; Walker, Mark (Institute of Cellular Medicine (Diabetes). The Medical School. Newcastle University) ; Koistinen, Heikki A. (Minerva Foundation Institute for Medical Research) ; Chandak, Giriraj Ratan (Academy of Scientific and Innovative Research (AcSIR)) ; Yajnik, Chittaranjan S. (Diabetology Research Centre. KEM Hospital and Research Centre) ; Mercader, Josep M. (Diabetes Unit and Center for Genomic Medicine. Massachusetts General Hospital) ; Tusié-Luna, Teresa (Unidad de Biología Molecular y Medicina Genómica. Instituto de Investigaciones Bimédicas UNAM/ Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ; Aguilar-Salinas, Carlos Alberto (Dirección de Nutrición and Unidad de Estudios de Enfermedades Metabólicas. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ; Gonzalez Villalpando, Clicerio (Instituto Nacional de Salud Publica y Centro de Estudios en Diabetes) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Fornage, Myriam (University of Texas Health Science at Houston) ; Tai, E. Shyong (Yong Loo Lin School of Medicine. National University of Singapore and National University Health System) ; van Dam, Rob M. (Yong Loo Lin School of Medicine. National University of Singapore and National University Health System) ; Lehtimäki, Terho (Department of Clinical Chemistry. Finnish Cardiovascular Research Center-Tampere. Faculty of Medicine and Health Technology. Tampere University) ; Chaturvedi, Nish (MRC Unit for Lifelong Health and Ageing at UCL) ; Yokota, Mitsuhiro (Kurume University School of Medicine) ; Liu, Jianjun (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Reilly, Dermot F. (Genetics. Merck Sharp & Dohme) ; McKnight, Amy Jayne (Centre for Public Health. Queen's University of Belfast) ; Kee, Frank (Queen's University Belfast) ; Jöckel, Karl-Heinz (University of Duisburg-Essen) ; McCarthy, Mark I. (University of Oxford) ; Palmer, Colin N. A. (University of Dundee. Ninwells Hospital and Medical School) ; Vitart, Veronique (University of Edinburgh. Western General Hospital) ; Hayward, Caroline (University of Edinburgh. Western General Hospital) ; Simonsick, Eleanor (Intramural Research Program. National Institute on Aging) ; van Duijn, Cornelia M. (Nuffield Department of Population Health. University of Oxford) ; Lu, Fan (The Eye Hospital. School of Ophthalmology and Optometry. Wenzhou Medical University) ; Qu, Jia (The Eye Hospital. School of Ophthalmology and Optometry. Wenzhou Medical University) ; Hishigaki, Haretsugu (Biomedical Technology Research Center. Tokushima Research Institute. Otsuka Pharmaceutical) ; Lin, Xu (Shanghai Chinese Academy of Sciences) ; März, Winfried (Medical University of Graz) ; Parra, Esteban J. (Department of Anthropology. University of Toronto at Mississauga) ; Cruz, Miguel (Instituto Mexicano del Seguro Social) ; Gudnason, Vilmundur (Faculty of Medicine. University of Iceland) ; Tardif, Jean-Claude (Department of Medicine. Faculty of Medecine. Université de Montréal) ; Lettre, Guillaume (Department of Medicine. Faculty of Medicine. Université de Montréal) ; 't Hart, Leen M. (Department of Biomedical Data Sciences. Section Molecular Epidemiology. Leiden University Medical Center) ; Elders, Petra J. M. (Amsterdam UMC. Department of General Practice and Elderly Care. Amsterdam Public Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Kumari, Meena (Institute of Social and Economic Research. University of Essex) ; Kivimaki, Mika (Department of Epidemiology and Public Health. University College London) ; van der Harst, Pim (Department of Cardiology. University Medical Center Groningen. University of Groningen) ; Spector, Tim (Department of Twin Research and Genetic Epidemiology. King's College London) ; Loos, Ruth J. F. (The Mindich Child Health and Development Institute. Icahn School of Medicine at Mount Sinai) ; Province, Michael A. (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Psaty, Bruce M. (Kaiser Permanent Washington Health Research Institute) ; Brandslund, Ivan (Institute of Regional Health Research. University of Southern Denmark) ; Pramstaller, Peter P. (Institute for Biomedicine. Eurac Research. Affiliated Institute of the University of Lübeck) ; Christensen, Kaare (Danish Aging Research Center. University of Southern Denmark) ; Ripatti, Samuli (Broad Institute of MIT and Harvard) ; Widén, Elisabeth (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Hakonarson, Hakon (Department of Pediatrics. Perelman School of Medicine. The University of Pennsylvania) ; Grant, Struan F. A. (Children's Hospital of Philadelphia (Pennsilvània)) ; Kiemeney, Lambertus A. L. M. (Radboud University Medical Center. Radboud Institute for Health Sciences) ; de Graaf, Jacqueline (Radboud University Medical Center. Radboud Institute for Health Sciences) ; Loeffler, Markus (LIFE Research Centre for Civilization Diseases. University of Leipzig) ; Kronenberg, Florian (Institute of Genetic Epidemiology. Department of Genetics and Pharmacology. Medical University of Innsbruck) ; Gu, Dongfeng (School of Medicine. Southern University of Science and Technology) ; Erdmann, Jeanette (University of Lübeck. Institute for Cardiogenetics) ; Schunkert, Heribert (Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V.. Partner site Munich Heart Alliance) ; Franks, Paul W. (Lund University Diabetes Centre) ; Linneberg, Allan (University of Copenhagen. Department of Clinical Medicine) ; Jukema, J. Wouter (Netherlands Heart Institute) ; Khera, Amit V. (Department of Medicine. Harvard Medical School) ; Männikkö, Minna (University of Oulu) ; Jarvelin, Marjo-Riitta (University of Oulu. Biocenter of Oulu) ; Kutalik, Zoltan (University Center for Primary Care and Public Health) ; Cucca, Francesco (University of Sassari) ; Mook-Kanamori, Dennis O. (Department of Public Health and Primary Care. Leiden University Medical Center) ; van Dijk, Ko Willems (Department of Human Genetics. Leiden University Medical Center) ; Watkins, Hugh (Division of Cardiovascular Medicine. Radcliffe Department of Medicine. John Radcliffe Hospital. University of Oxford) ; Strachan, David P. (Population Health Research Institute. St George's University of London) ; Grarup, Niels (Novo Nordisk Foundation Center for Basic Metabolic Research. Faculty of Health and Medical Sciences. University of Copenhagen) ; Sever, Peter (National Heart and Lung Institute. Imperial College London) ; Poulter, Neil (Imperial College London) ; Rotter, Jerome I. (The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. The Institute for Translational Genomics and Population Sciences, Department of Pediatrics) ; Dantoft, Thomas M. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Karpe, Fredrik (NIHR Oxford Biomedical Research Centre. Churchill Hospital) ; Neville, Matt J. (NIHR Oxford Biomedical Research Centre. Churchill Hospital) ; Timpson, Nicholas J. (University of Bristol) ; Cheng, Ching-Yu (Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP). Duke-NUS Medical School) ; Wong, Tien-Yin (Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP). Duke-NUS Medical School) ; Khor, Chiea Chuen (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Sabanayagam, Charumathi (Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP). Duke-NUS Medical School) ; Peters, Annette (DZHK (German Centre for Cardiovascular Research). Munich Heart Alliance Partner Site) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Hattersley, Andrew T. (University of Exeter Medical School. University of Exeter) ; Pedersen, Nancy L. (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Boomsma, Dorret I. (Amsterdam Reproduction and Development Research Institute. VU Medical Center Amsterdam) ; de Geus, Eco J. C. (Amsterdam Public Health Research Institute. VU Medical Center Amsterdam) ; Cupples, L. Adrienne (Framingham Heart Study. National Heart. Lung. and Blood Institute. US National Institutes of Health) ; van Meurs, Joyce B. J. (Department of Epidemiology. Erasmus MC. University Medical Center Rotterdam) ; Ghanbari, Mohsen (Department of Genetics. School of Medicine. Mashhad University of Medical Sciences) ; Gordon-Larsen, Penny (Carolina Population Center. University of North Carolina) ; Huang, Wei (Department of Genetics. Shanghai-MOST Key Laboratory of Health and Disease Genomics. Chinese National Human Genome Center at Shanghai) ; Kim, Young Jin (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Tabara, Yasuharu (Center for Genomic Medicine. Kyoto University Graduate School of Medicine) ; Wareham, Nicholas J. (University of Cambridge (Regne Unit). School of Clinical Medicine) ; Langenberg, Claudia (University of Cambridge (Regne Unit). School of Clinical Medicine) ; Zeggini, Eleftheria (TUM School of Medicine. Technical University of Munich (TUM) and Klinikum Rechts der Isar) ; Kuusisto, Johanna (Institute of Clinical Medicine. Internal Medicine. University of Eastern Finland and Kuopio University Hospital) ; Laakso, Markku (Institute of Clinical Medicine. Internal Medicine. University of Eastern Finland and Kuopio University Hospital) ; Ingelsson, Erik (Stanford Diabetes Research Center. Stanford University) ; Abecasis, Goncalo (Regeneron Pharmaceuticals) ; Chambers, John C. (Imperial College Healthcare NHS Trust. Imperial College London) ; Kooner, Jaspal S. (National Heart and Lung Institute. Imperial College London) ; de Vries, Paul S. (Human Genetics Center. Department of Epidemiology. Human Genetics. and Environmental Sciences. School of Public Health. The University of Texas Health Science Center at Houston) ; Morrison, Alanna (Human Genetics Center. Department of Epidemiology. Human Genetics. and Environmental Sciences. School of Public Health. The University of Texas Health Science Center at Houston) ; North, Kari E. (Department of Epidemiology. University of North Carolina) ; Daviglus, Martha (Institute for Minority Health Research. University of Illinois College of Medicine) ; Kraft, Peter (Department of Biostatistics. Harvard T. H. Chan School of Public Health) ; Martin, Nicholas G (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Whitfield, John B (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Abbas, Shahid (Faisalabad Institute of Cardiology) ; Saleheen, Danish (Department of Cardiology. Columbia University Irving Medical Center) ; Walters, Robin G. (Big Data Institute. University of Oxford) ; Holmes, Michael V (National Institute for Health Research Oxford Biomedical Research Centre. Oxford University Hospitals) ; Black, Corri (Aberdeen Centre for Health Data Science (Aberdeen, Regne Unit)) ; Smith, Blair H (Division of Population Health and Genomics. Ninewells Hospital and Medical School. University of Dundee) ; Justice, Anne E. (Biomedical and Translational Informatics. Geisinger Health) ; Baras, Aris (Regeneron Pharmaceuticals) ; Buring, Julie E. (Harvard Medical School) ; Ridker, Paul M. (Harvard Medical School) ; Chasman, Daniel I. (Harvard Medical School) ; Kooperberg, Charles (Fred Hutchinson Cancer Research Center. Division of Public Health Sciences) ; Wei, Wei-Qi (Department of Biomedical Informatics. Vanderbilt University Medical Center) ; Jarvik, Gail P. (Departments of Medicine (Medical Genetics) and Genome Sciences. University of Washington Medical Center) ; Namjou, Bahram (Center for Autoimmune Genomics and Etiology. Cincinnati Children's Hospital Medical Center (CCHMC)) ; Hayes, M. Geoffrey (Center for Genetic Medicine. Northwestern University. Feinberg School of Medicine) ; Ritchie, Marylyn D. (Department of Genetics. Institute for Biomedical Informatics. Perelman School of Medicine. University of Pennsylvania) ; Jousilahti, Pekka (Department of Public Health and Welfare. Finnish Institute for Health and Welfare) ; Salomaa, Veikko (Department of Public Health and Welfare. Finnish Institute for Health and Welfare) ; Hveem, Kristian (Department of Medicine. Levanger Hospital. Nord-Trøndelag Hospital Trust) ; Åsvold, Bjørn Olav (Department of Endocrinology. St Olavs Hospital. Trondheim University Hospital) ; Kubo, Michiaki (RIKEN Center for Integrative Medical Sciences) ; Kamatani, Yoichiro (The University of Tokyo. Department of Computational Biology and Medical Sciences) ; Okada, Yukinori (Integrated Frontier Research for Medical Science Division. Institute for Open and Transdisciplinary Research Initiatives. Osaka University) ; Murakami, Yoshinori (The University of Tokyo. Institute of Medical Science) ; Thorsteinsdottir, Unnur (Faculty of Medicine. University of Iceland) ; Stefansson, Kari (Faculty of Medicine. University of Iceland) ; Ho, Yuk-Lam (VA Boston Healthcare System) ; Lynch, Julie A. (University of Massachusetts) ; Rader, Daniel J. (Department of Medicine. Perelman School of Medicine. University of Pennsylvania) ; Tsao, Philip S. (Cardiovascular Institute. Stanford University School of Medicine)
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use. Despite advances in prevention and treatment, in particular through reducing low-density lipoprotein cholesterol levels, heart disease remains the leading cause of death worldwide. [...]
2021 - 10.1038/s41586-021-04064-3
Nature, Vol. 600 Núm. 7890 (12 2021) , p. 675-679  
3.
13 p, 1009.7 KB Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer / Couch, Fergus J. (Mayo Clinic) ; Kuchenbaecker, Karoline B. (University of Cambridge) ; Michailidou, Kyriaki (University of Cambridge) ; Mendoza-Fandino, Gustavo A. (H. Lee Moffitt Cancer Center and Research Institute) ; Nord, Silje (Oslo University Hospital (Oslo, Noruega)) ; Lilyquist, Janna (Mayo Clinic) ; Olswold, Curtis (Mayo Clinic) ; Hallberg, Emily (Mayo Clinic) ; Agata, Simona (Istituto Oncologico Veneto IOV-IRCCS) ; Ahsan, Habibul (The University of Chicago) ; Aittomäki, Kristiina (Helsinki University Central Hospital) ; Ambrosone, Christine B (Roswell Park Cancer Institute) ; Andrulis, Irene L. (University of Toronto) ; Anton-Culver, Hoda (University of California Irvine) ; Arndt, Volker (German Cancer Research Center) ; Arun, Banu K. (University of Texas MD Anderson Cancer Center) ; Arver, Brita (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Barile, Monica (Istituto Europeo di Oncologia) ; Barkardottir, Rosa B. (Landspitali University Hospital (Islàndia)) ; Barrowdale, Daniel (University of Cambridge) ; Beckmann, Lars (Institute for Quality and Efficiency in Health Care) ; Beckmann, Matthias W. (University Breast Center Franconia) ; Benitez, Javier (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Blank, Stephanie V. (New York University School of Medicine) ; Blomqvist, Carl (University of Helsinki and Helsinki University Central Hospital) ; Bogdanova, Natalia V. (Hannover Medical School) ; Bojesen, Stig E. (Copenhagen University Hospital) ; Bolla, Manjeet K. (University of Cambridge) ; Bonanni, Bernardo (Istituto Europeo di Oncologia) ; Brauch, Hiltrud (University of Tübingen) ; Brenner, Hermann (German Cancer Research Center and National Center for Tumor Diseases) ; Burwinkel, Barbara (University of Heidelberg) ; Buys, Saundra (University of Utah School of Medicine) ; Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Caligo, Maria (University Hospital of Pisa (Pisa, Itàlia)) ; Canzian, Federico (German Cancer Research Center) ; Carpenter, Jane (University of Sydney) ; Chang-Claude, Jenny (German Cancer Research Center) ; Chanock, Stephen (Centro Nacional de Investigaciones Oncológicas) ; Chung, Wendy (Columbia University) ; Claes, Kathleen (Ghent University) ; Cox, Angela (University of Sheffield) ; Cross, Simon S. (University of Sheffield) ; Cunningham, Julie M. (Mayo Clinic) ; Czene, Kamila (Karolinska Institutet (Estocolm, Suècia)) ; Daly, Mary B. (Fox Chase Cancer Center) ; Damiola, Francesca (Université Lyon) ; Darabi, Hatef (Karolinska Institutet (Estocolm, Suècia)) ; De la Hoya, Miguel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Devilee, Peter (Leiden University Medical Center) ; Diez, Orland (Vall d'Hebron Institut d'Oncologia) ; Ding, Yuan C. (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica)) ; Dolcetti, Riccardo (CRO Aviano National Cancer Institute) ; Domchek, Susan M. (University of Pennsylvania) ; Dorfling, Cecilia M. (University of Pretoria) ; dos-Santos-Silva, Isabel (London School of Hygiene and Tropical Medicine) ; Dumont, Martine (Laval University) ; Dunning, Alison M. (University of Cambridge) ; Eccles, Diana M. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ; Ehrencrona, Hans (Lund University Hospital) ; Ekici, Arif B. (Comprehensive Cancer Center -EMN) ; Eliassen, Heather (Harvard School of Public Health) ; Ellis, Steve (University of Cambridge) ; Fasching, Peter A. (University Breast Center Franconia) ; Figueroa, Jonine (National Cancer Institute) ; Flesch-Janys, Dieter (University Clinic Hamburg-Eppendorf) ; Försti, Asta (Lund University) ; Fostira, Florentia (Memokritos', Aghia Paraskevi Attikis) ; Foulkes, William D. (McGill University) ; Friebel, Tara (University of) ; Friedman, Eitan (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ; Frost, Debra (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Gabrielson, Marike (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Gammon, Marilie D. (Department of Epidemiology, University of) ; Ganz, Patricia A. (UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center) ; Gapstur, Susan M. (Epidemiology Research Program, American Cancer Society) ; Garber, Judy (Cancer Risk and Prevention Clinic, Dana Farber Cancer Institute) ; Gaudet, Mia M. (Epidemiology Research Program, American Cancer Society) ; Gayther, Simon A. (Department of Biomedical Sciences, Cedars Sinai Medical Center) ; Gerdes, Anne-Marie (Copenhagen University Hospital Rigshospitalet) ; Ghoussaini, Maya (University of Cambridge) ; Giles, Graham G. (Cancer Council Victoria) ; Glendon, Gord (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ; Godwin, Andrew K. (University of Kansas Medical Center) ; Goldberg, Mark S. (Royal Victoria Hospital) ; Goldgar, David E. (University of Utah School of Medicine) ; González-Neira, Anna (Centro Nacional de Investigaciones Oncológicas) ; Greene, Mark H. (Clinical Genetics Branch) ; Gronwald, Jacek (Pomeranian Medical University) ; Guénel, Pascal (Inserm (National Institute of Health and Medical Research)) ; Gunter, Marc (Imperial College London) ; Haeberle, Lothar (University Breast Center Franconia) ; Haiman, Christopher A. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Hamann, Ute (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ; Hansen, Thomas V. O. (Copenhagen University Hospital Rigshospitalet) ; Hart, Steven (Department of Health Sciences Research, Mayo Clinic) ; Healey, Sue (Department of Genetics, QIMR Berghofer Medical Research Institute) ; Heikkinen, Tuomas (Helsinki University Central Hospital) ; Henderson, Brian E. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Herzog, Josef (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ; Hogervorst, Frans B. L. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Hollestelle, Antoinette (Department of Medical Oncology, Erasmus MC Cancer Institute) ; Hooning, Maartje J. (Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center) ; Hoover, Robert (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Hopper, John L. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Humphreys, Keith (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Hunter, David J. (Program in Molecular and Genetic Epidemiology, Harvard School of Public Health) ; Huzarski, Tomasz (Department of Genetics and Pathology, Pomeranian Medical University) ; Imyanitov, Evgeny N. (N.N. Petrov Institute of Oncology) ; Isaacs, Claudine (Lombardi Comprehensive Cancer Center, Georgetown University) ; Jakubowska, Anna (Department of Genetics and Pathology, Pomeranian Medical University) ; James, Paul (Department of Oncology, The University of Melbourne) ; Janavicius, Ramunas (State Research Institute Centre for Innovative Medicine) ; Jensen, Uffe Birk (Aarhus University Hospital (Aarhus, Dinamarca)) ; John, Esther M. (Department of Epidemiology, Cancer Prevention Institute of California) ; Jones, Michael (Division of Genetics and Epidemiology, Institute of Cancer Research) ; Kabisch, Maria (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ; Kar, Siddhartha (Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge) ; Karlan, Beth Y. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Khan, Sofia (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ; Khaw, Kay-Tee (Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory) ; Kibriya, Muhammad G. (Department of Health Studies, The University of Chicago) ; Knight, Julia A. (Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ; Ko, Yon-Dschun (Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus) ; Konstantopoulou, Irene (Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ; Kosma, Veli-Matti (School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ; Kristensen, Vessela (Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet) ; Kwong, Ava (Department of Surgery, The University of Hong Kong) ; Laitman, Yael (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ; Lambrechts, Diether (Vesalius Research Center, VIB) ; Lazaro, Conxi (Institut Català d'Oncologia) ; Lee, Eunjung (Department of Preventive Medicine, University of Southern California) ; Le Marchand, Loic (Cancer Epidemiology Program, University of Cancer Center) ; Lester, Jenny (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Lindblom, Annika (Karolinska Institutet (Estocolm, Suècia). Department of Molecular Medicine and Surgery) ; Lindor, Noralane (Health Sciences Research, Mayo Clinic) ; Lindstrom, Sara (Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health) ; Liu, Jianjun (Human Genetics Division, Genome Institute of Singapore) ; Long, Jirong (Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Lubinski, Jan (Department of Genetics and Pathology, Pomeranian Medical University) ; Mai, Phuong L. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ; Makalic, Enes (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Malone, Kathleen E. (Department of Epidemiology, School of Public Health and Community Medicine, University of Washington) ; Mannermaa, Arto (School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ; Manoukian, Siranoush (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ; Margolin, Sara (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Marme, Frederik (Department of Obstetrics and Gynecology, University of Heidelberg) ; Martens, John W. M. (Department of Medical Oncology, Erasmus MC Cancer Institute) ; McGuffog, Lesley (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Meindl, Alfons (Department of Gynaecology and Obstetrics, Technical University of Munich) ; Miller, Austin (NRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute) ; Milne, Roger L. (Cancer Epidemiology Centre (Melbourne, Austràlia)) ; Miron, Penelope (Department of Genomics and Genome Sciences, Case Western Reserve University Medical School) ; Montagna, Marco (Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS) ; Mazoyer, Sylvie (INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon) ; Mulligan, Anna M. (Department of Laboratory Medicine and Pathobiology, University of Toronto) ; Muranen, Taru A. (Helsinki University Central Hospital) ; Nathanson, Katherine L. (Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania) ; Neuhausen, Susan L. (Department of Population Sciences, Beckman Research Institute of City of Hope) ; Nevanlinna, Heli (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ; Nordestgaard, Børge G. (Copenhagen University Hospital) ; Nussbaum, Robert L. (Invitae Corporation) ; Offit, Kenneth (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ; Olah, Edith (Department of Molecular Genetics, National Institute of Oncology) ; Olopade, Olufunmilayo I. (Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center) ; Olson, Janet E. (Department of Health Sciences Research, Mayo Clinic) ; Osorio, Ana (Centro Nacional de Investigaciones Oncológicas) ; Park, Sue K. (Department of Preventive Medicine and Biomedical Science, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University) ; Peeters, Petra H. (MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London) ; Peissel, Bernard (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ; Peterlongo, Paolo (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare) ; Peto, Julian (Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine) ; Phelan, Catherine M. (Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute) ; Pilarski, Robert (Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University) ; Poppe, Bruce (Center for Medical Genetics, Ghent University) ; Pylkäs, Katri (Oulu University Hospital (Finlàndia)) ; Radice, Paolo (Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ; Rahman, Nazneen (Section of Cancer Genetics, Institute of Cancer Research) ; Rantala, Johanna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Rappaport, Christine (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ; Rennert, Gad (Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine) ; Richardson, Andrea (Department of Pathology, Johns Hopkins University School of Medicine) ; Robson, Mark (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ; Romieu, Isabelle (International Agency for Research on Cancer) ; Rudolph, Anja (Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)) ; Rutgers, Emiel J. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ; Sanchez, Maria-Jose (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Santella, Regina M. (Department of Environmental Health Sciences, Columbia University) ; Sawyer, Elinor J. (Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital) ; Schmidt, Daniel F. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ; Schmidt, Marjanka K. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ; Schmutzler, Rita K. (Center for Molecular Medicine Cologne (CMMC), University of Cologne) ; Schumacher, Fredrick (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ; Scott, Rodney (Division of Genetics, Hunter Area Pathology Service, John Hunter Hospital) ; Senter, Leigha (Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University) ; Sharma, Priyanka (Department of Hematology and Oncology, University of Kansas Medical Center) ; Simard, Jacques (Centre Hospitalier Universitaire de Québec Research Center, Laval University) ; Singer, Christian F. (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ; Sinilnikova, Olga M. (Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard) ; Soucy, Penny (Centre Hospitalier Universitaire de Québec Research Center, Laval University) ; Southey, Melissa (Department of Pathology, The University of Melbourne) ; Steinemann, Doris (Hannover Medical School) ; Stenmark-Askmalm, Marie (Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University) ; Stoppa-Lyonnet, Dominique (Université Paris Descartes) ; Swerdlow, Anthony (Division of Genetics and Epidemiology, Institute of Cancer Research) ; Szabo, Csilla I. (National Human Genome Research Institute, National Institutes of Health) ; Tamimi, Rulla (Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health) ; Tapper, William (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ; Teixeira, Manuel R. (Biomedical Sciences Institute (ICBAS), Porto University) ; Teo, Soo-Hwang (University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya) ; Terry, Mary Beth (Department of Epidemiology, Mailman School of Public Health, Columbia University) ; Thomassen, Mads (Odense University Hospital (Dinamarca)) ; Thompson, Deborah (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Tihomirova, Laima (Latvian Biomedical Research and Study Centre) ; Toland, Amanda E. (Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University) ; Tollenaar, Robert A. E. M. (Department of Surgical Oncology, Leiden University Medical Center) ; Tomlinson, Ian (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Truong, Thérèse (Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer) ; Tsimiklis, Helen (Department of Pathology, The University of Melbourne) ; Teulé, Alex (Institut d'Investigació Biomèdica de Bellvitge) ; Tumino, Rosario (Cancer Registry and Histopathology Unit, 'Civic-M.P. Arezzo' Hospital) ; Tung, Nadine (Department of Medical Oncology, Beth Israel Deaconess Medical Center) ; Turnbull, Clare (Section of Cancer Genetics, Institute of Cancer Research) ; Ursin, Giski (Cancer Registry of Norway, Institute of Population-Based Cancer Research) ; van Deurzen, Carolien H. M. (Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center) ; van Rensburg, Elizabeth J. (Department of Genetics, University of Pretoria) ; Varon-Mateeva, Raymonda (Institute of Human Genetics, Charite Berlin) ; Wang, Zhaoming (Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Wang-Gohrke, Shan (University Hospital of Ulm (Alemanya)) ; Weiderpass, Elisabete (Genetic Epidemiology Group, Folkhälsan Research Center) ; Weitzel, Jeffrey N. (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ; Whittemore, Alice (Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine) ; Wildiers, Hans (Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals) ; Winqvist, Robert (Oulu University Hospital (Finlàndia)) ; Yang, Xiaohong R. (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ; Yannoukakos, Drakoulis (Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ; Yao, Song (Department of Cancer Prevention and Control, Roswell Park Cancer Institute) ; Zamora, M. Pilar (Hospital Universitario La Paz (Madrid)) ; Zheng, Wei (Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ; Hall, Per (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Kraft, Peter (Department of Biostatistics, Harvard School Of Public Health) ; Vachon, Celine (Department of Health Sciences Research, Mayo Clinic) ; Slager, Susan (Department of Health Sciences Research, Mayo Clinic) ; Chenevix-Trench, Georgia (Cancer Division, QIMR Berghofer Medical Research Institute) ; Pharoah, Paul D. P. (Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge) ; Monteiro, Alvaro A. N. (Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute) ; García-Closas, Montserrat (Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ; Easton, Douglas F. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Antoniou, Antonis C. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ; Universitat Autònoma de Barcelona
Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P <5 × 10 −8) with oestrogen receptor (ER)-negative breast cancer and BRCA1 -associated breast cancer risk. [...]
2016 - 10.1038/ncomms11375
Nature communications, Vol. 7 (04 2016)  
4.
11 p, 1.8 MB Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer / Klein, Alison P. (Johns Hopkins School of Medicine, Baltimore, USA) ; Wolpin, Brian M. (Dana-Farber Cancer Institute, Boston, USA) ; Risch, Harvey A. (Yale School of Public Health, New Haven, USA) ; Stolzenberg-Solomon, Rachael Z. (National Institutes of Health, Bethesda, USA) ; Mocci, Evelina (Johns Hopkins School of Medicine, Baltimore, USA) ; Zhang, Mingfeng (National Cancer Institute, National Institutes of Health, Bethesda, USA) ; Canzian, Federico (Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany) ; Childs, Erica J. (Johns Hopkins School of Medicine, Baltimore, USA) ; Hoskins, Jason W. (National Cancer Institute, National Institutes of Health, Bethesda, USA) ; Jermusyk, Ashley (National Cancer Institute, National Institutes of Health, Bethesda, USA) ; Zhong, Jun (National Cancer Institute, National Institutes of Health, Bethesda, USA) ; Chen, Fei (Johns Hopkins School of Medicine, Baltimore, USA) ; Albanes, Demetrius (National Cancer Institute, National Institutes of Health, Bethesda, USA) ; Andreotti, Gabriella (National Institutes of Health, Bethesda, USA) ; Arslan, Alan A. (New York University School of Medicine, New York, USA) ; Babic, Ana (Dana-Farber Cancer Institute, Boston, USA) ; Bamlet, William R. (Mayo Clinic College of Medicine, Rochester, USA) ; Beane-Freeman, Laura (National Cancer Institute, National Institutes of Health, Bethesda, USA) ; Berndt, Sonja (National Institutes of Health, Bethesda, USA) ; Blackford, Amanda (Johns Hopkins School of Medicine, Baltimore, USA) ; Borges, Michael (Johns Hopkins School of Medicine, Baltimore, USA) ; Borgida, Ayelet (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, M5G 1×5, Canada.) ; Bracci, Paige M. (University of California, San Francisco, USA) ; Brais, Lauren (Dana-Farber Cancer Institute, Boston, USA) ; Brennan, Paul (International Agency for Research on Cancer (IARC), Lyon, France) ; Brenner, Hermann (Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany) ; Bueno-de-Mesquita, Bas (National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands) ; Buring, Julie (Division of Preventive Medicine, Brigham and Women's Hospital, Boston) ; Campa, Daniele (University of Pisa) ; Capurso, Gabriele (University of Rome) ; Cavestro, Giulia Martina (Vita-Salute San Raffaele University, Milan) ; Chaffee, Kari G (Mayo Clinic College of Medicine, Rochester, USA) ; Chung, Charles C. (National Institutes of Health, Bethesda, USA) ; Cleary, Sean (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ; Cotterchio, Michelle (University of Toronto.) ; Dijk, Frederike (University of Amsterdam. Department of Pathology, Academic Medical Center) ; Duell, Eric J. (Institut d'Investigació Biomèdica de Bellvitge) ; Foretova, Lenka (Masaryk Memorial Cancer Institute. Department of Cancer Epidemiology and Genetics, Brno, Czech Republic.) ; Fuchs, Charles (Yale Cancer Center, New Haven, USA) ; Funel, Niccola (University of Pisa.) ; Gallinger, Steven (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ; M. Gaziano, J. Michael (Boston VA Healthcare System) ; Gazouli, Maria (National and Kapodistrian University of Athens) ; Giles, Graham G. (Monash University. Department of Epidemiology and Preventive Medicine, Melbourne, Australia) ; Giovannucci, Edward (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Goggins, Michael (Johns Hopkins School of Medicine. Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Baltimore) ; Goodman, Gary E. (Fred Hutchinson Cancer Research Center. Division of Public Health Sciences, Seattle, USA) ; Goodman, Phyllis J. (Fred Hutchinson Cancer Research Center. SWOG Statistical Center, Seattle, USA) ; Hackert, Thilo (University Hospital Heidelberg, Germany) ; Haiman, Christopher A (University of Southern California, USA) ; Hartge, Patricia (National Institutes of Health, Bethesda, USA) ; Hasan, Manal (University of Texas MD Anderson Cancer Center, USA) ; Hegyi, Peter (University of Szeged, Szeged, Hungary) ; Helzlsouer, Kathy J. (National Institutes of Health, Bethesda, USA) ; Herman, Joseph (Johns Hopkins School of Medicine. Baltimore, USA) ; Holcatova, Ivana (Charles University, Prague, Czech Republic) ; Holly, Elizabeth A. (University of California, San Francisco) ; Hoover, Robert (National Institutes of Health, Bethesda, USA) ; Hung, Rayjean J. (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ; Jacobs, Eric J. (American Cancer Society. Epidemiology Research Program, Atlanta) ; Jamroziak, Krzysztof (Institute of Hematology and Transfusion Medicine, Warsaw, Poland) ; Janout, Vladimir (Faculty of Medicine, University of Olomouc, Czech Republic) ; Kaaks, Rudolf (German Cancer Research Center (DKFZ), Heidelberg, Germany) ; Khaw, Kay-Tee (University of Cambridge) ; Klein, Eric A. (Cleveland Clinic) ; Kogevinas, M (Hospital del Mar (Barcelona, Catalunya)) ; Kooperberg, Charles (Fred Hutchinson Cancer Research Center, Seattle) ; Kulke, Matthew H. (Dana-Farber Cancer Institute, Boston) ; Kupcinskas, Juozas (Lithuanian University of Health Sciences, Kaunas, Lithuania) ; Kurtz, Robert J. (Memorial Sloan Kettering Cancer Center, New York, USA) ; Laheru, Daniel (Johns Hopkins School of Medicine, Baltimore, USA) ; Landi, Stefano (University of Pisa) ; Lawlor, Rita T. (University and Hospital Trust of Verona) ; Lee, I.-Min (Harvard School of Public Health, Boston) ; LeMarchand, Loic (University of Hawaii Cancer Center, Honolulu, USA) ; Lu, Lingeng (Yale School of Public Health, New Haven, USA) ; Malats, Núria (Centro de Investigación Biomédica en Red de Cáncer, Madrid) ; Mambrini, Andrea (Oncology Department, ASL1 Massa Carrara, Italy) ; Mannisto, Satu (National Institute for Health and Welfare, Helsinki, Finland) ; Milne, Roger L. (The University of Melbourne, Australia) ; Mohelníková-Duchoňová, Beatrice (Palacky University Olomouc and University Hospital, Czech Republic) ; Neale, Rachel E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Neoptolemos, John P. (University of Heidelburg, Heidelberg, Germany) ; Oberg, Ann L. (Mayo Clinic College of Medicine, Rochester, USA) ; Olson, Sara H. (Memorial Sloan Kettering Cancer Center, New York, USA) ; Orlow, Irene (Memorial Sloan Kettering Cancer Center, New York, USA) ; Pasquali, Claudio (University of Padua, Italy) ; Patel, Alpa V. (American Cancer Society, Atlanta) ; Peters, Ulrike (Fred Hutchinson Cancer Research Center, Seattle) ; Pezzilli, Raffaele (Sant'Orsola-Malpighi Hospital, Bologna, Italy) ; Porta, Miquel 1957- (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Real, Francisco X. (Universitat Pompeu Fabra) ; Rothman, Nathaniel (National Institutes of Health, Bethesda, USA) ; Scelo, Ghislaine (International Agency for Research on Cancer (IARC), Lyon, France) ; Sesso, Howard D. (Harvard T.H. Chan School of Public Health. Department of Epidemiology) ; Severi, Gianluca (Université Paris-Saclay, France) ; Shu, Xiao-Ou (Vanderbilt University School of Medicine, Nashville, USA) ; Silverman, Debra (National Institutes of Health, Bethesda, USA) ; Smith, Jill P. (Georgetown University, Washington, USA) ; Soucek, Pavel (Charles University, Pilsen, Czech Republic.) ; Sund, Malin (Umeå University, Sweden) ; Talar-Wojnarowska, Renata (Medical University of Łodz, Poland) ; Tavano, Francesca (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Italy) ; Thornquist, Mark D. (Fred Hutchinson Cancer Research Center, Seattle) ; Tobias, Geoffrey S. (National Institutes of Health, Bethesda, USA) ; Van Den Eeden, Stephen K. (Kaiser Permanente Northern California, USA) ; Vashist, Yogesh (University Hamburg-Eppendorf, Germany) ; Visvanathan, Kala (Johns Hopkins Bloomberg School of Public Health, Baltimore, USA) ; Vodicka, Pavel (Academy of Sciences of the Czech Republic, Prague, Czech Republic) ; Wactawski-Wende, Jean (University at Buffalo, USA) ; Wang, Zhaoming (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ; Wentzensen, Nicolas (National Cancer Institute, National Institutes of Health, Bethesda, USA) ; White, Emily (University of Washington, USA) ; Yu, Herbert (University of Hawaii Cancer Center, USA) ; Yu, Kai (National Institutes of Health, Bethesda, USA) ; Zeleniuch-Jacquotte, Anne (New York University School of Medicine, USA) ; Zheng, Wei (Vanderbilt University School of Medicine, Nashville, USA) ; Kraft, Peter (Harvard School of Public Health, USA) ; Li, Donghui (University of Texas MD Anderson Cancer Center, USA) ; Chanock, Stephen (National Institutes of Health, Bethesda, USA) ; Obazee, Ofure (German Cancer Research Center (DKFZ), Heidelberg, Germany) ; Petersen, Gloria M. (Mayo Clinic College of Medicine, Rochester, USA) ; Amundadottir, Laufey T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica))
In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe and the United States combined. To identify common susceptibility alleles, we performed the largest pancreatic cancer GWAS to date, including 9040 patients and 12,496 controls of European ancestry from the Pancreatic Cancer Cohort Consortium (PanScan) and the Pancreatic Cancer Case-Control Consortium (PanC4). [...]
2018 - 10.1038/s41467-018-02942-5
Nature communications, Vol. 9 (february 2018)  
5.
17 p, 5.3 MB Associations of autozygosity with a broad range of human phenotypes / Clark, David W. (University of Edinburgh) ; Okada, Yukinori (Osaka University, Suita) ; Moore, Kristjan H. S. (deCODE genetics/Amgen Inc., Reykjavik, Iceland) ; Mason, Dan (Bradford Teaching Hospitals NHS Trust, Bradford, UK) ; Pirastu, Nicola (University of Edinburgh, Usher Institute) ; Gandin, Ilaria (University of Trieste) ; Mattsson, Hannele (University of Helsinki) ; Barnes, Catriona L. K. (University of Edinburgh) ; Lin, Kuang (University of Oxford) ; Zhao, Jing Hua (University of Cambridge) ; Deelen, Patrick (University Medical Centre Groningen, University of Groningen) ; Rohde, Rebecca (University of North Carolina. Department of Epidemiology) ; Schurmann, Claudia (Ichan School of Medicine at Mount Sinai) ; Guo, Xiuqing (The Institute for Translational Genomics and Population Sciences, Torrance, California, USA) ; Giulianini, Franco (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Zhang, Weihua (Ealing Hospital, Middlesex) ; Medina-Gomez, Carolina (Erasmus University Medical Center) ; Karlsson, Robert (Karolinska Institutet (Estocolm, Suècia)) ; Bao, Yanchun (University of Essex) ; Bartz, Traci M. (University of Washington) ; Baumbach, Clemens (Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg) ; Biino, Ginevra (National Research Council of Italy) ; Bixley, Matthew J. (University of Otago) ; Brumat, Marco (University of Trieste) ; Chai, Jin-Fang (National University of Singapore, Singapore) ; Corre, Tanguy (Swiss Institute of Bioinformatics) ; Cousminer, Diana L. (University of Pennsylvania) ; Dekker, Annelot M. (Utrecht University) ; Eccles, David (Instituto de Investigación Biomédica de Málaga) ; van Eijk, Kristel R. (Utrecht University) ; Fuchsberger, Christian (Affiliated Institute of the University of Lübeck, Bolzano, Italy) ; Gao, He (Imperial College London) ; Germain, Marine (ICAN Institute for Cardiometabolism and Nutrition) ; Gordon, Scott D. (QIMR Berghofer Institute of Medical Research) ; de Haan, Hugoline G. (Leiden University Medical Center) ; Harris, Sarah E. (University of Edinburgh) ; Hofer, Edith (Medical University of Graz) ; Huerta-Chagoya, Alicia (CONACyT, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 03940 México) ; Igartua, Catherine (University of Chicago. Department of Human Genetics) ; Jansen, Iris E. (VU University Medical Center, Amsterdam Neuroscience. Alzheimer Center Department of Neurology) ; Jia, Yucheng (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502 USA) ; Kacprowski, Tim (TUM School of Life Sciences Weihenstephan, Technical University of Munich. Chair of Experimental Bioinformatics) ; Karlsson, Torgny (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Kleber, Marcus E. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Li, Shengchao Alfred (Leidos Biomedical Research, Inc., Frederick National Lab for Cancer Research. Cancer Genomics Research Laboratory) ; Li-Gao, Ruifang (Leiden University Medical Center. Department of Clinical Epidemiology) ; Mahajan, Anubha (University of Oxford. Wellcome Centre for Human Genetics) ; Matsuda, Koichi (Graduate school of Frontier Sciences, The University of Tokyo. Department of Computational Biology and Medical Sciences) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Meng, Weihua (Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee) ; Montasser, May E. (University of Maryland, School of Medicine. Program for Personalized and Genomic Medicine, Department of Medicine) ; van der Most, Peter J. (University of Groningen, University Medical Center Groningen. Department of Epidemiology) ; Munz, Matthias (Humboldt-Universität zu Berlin) ; Nutile, Teresa (Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR) ; Palviainen, Teemu (Finnish Institute for Molecular Medicine, University of Helsinki) ; Prasad, Gauri (Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology) ; Prasad, Rashmi B. (Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, 20502 Sweden) ; Priyanka, Tallapragada Divya Sri (CSIR-Centre for Cellular and Molecular Biology. Genomic Research on Complex diseases (GRC Group)) ; Rizzi, Federica (University of Milano. Department of Health Sciences) ; Salvi, Erika (IRCCS Foundation Carlo Besta Neurological Institute. Neuroalgology Unit) ; Sapkota, Bishwa R. (University of Oklahoma Health Sciences Center. Department of Pediatrics, College of Medicine) ; Shriner, Daniel (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Skotte, Line (Statens Serum Institut. Department of Epidemiology Research) ; Smart, Melissa C. (Institute for Social and Economic Research, University of Essex) ; Smith, Albert Vernon (University of Iceland. Faculty of Medicine, School of Health Sciences) ; van der Spek, Ashley (Erasmus University Medical Center. Department of Epidemiology) ; Spracklen, Cassandra N. (University of North Carolina. Department of Genetics) ; Strawbridge, Rona J. (Karolinska Institutet. Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine) ; Tajuddin, Salman M. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Trompet, Stella (Leiden University Medical Center. Section of Gerontology and Geriatrics, Department of Internal Medicine) ; Turman, Constance (Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health) ; Verweij, Niek (University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands) ; Viberti, Clara (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; Wang, Lihua (Washington University School of Medicine. Division of Statistical Genomics, Department of Genetics) ; Warren, Helen R. (William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London. Department of Clinical Pharmacology) ; Wootton, Robyn E. (School of Psychological Science, University of Bristol) ; Yanek, Lisa R. (Johns Hopkins University School of Medicine. Department of Medicine, GeneSTAR Research Program) ; Yao, Jie (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502 USA) ; Yousri, Noha A. (Alexandria University. Computer and Systems Engineering) ; Zhao, Wei (University of Michigan. Department of Epidemiology, School of Public Health) ; Adeyemo, Adebowale A. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Afaq, Saima (Imperial College London. Department of Epidemiology and Biostatistics) ; Aguilar-Salinas, Carlos Alberto (Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud. Unidad de Investigacion de Enfermades Metabolicas) ; Akiyama, Masato (Graduate School of Medical Sciences, Kyushu University, Fukuoka. Department of Ophthalmology) ; Albert, Matthew L. (Genentech Inc. Department of Cancer Immunology) ; Allison, Matthew A. (UC San Diego School of Medicine. Division of Preventive Medicine, Department of Family Medicine and Public Health) ; Alver, Maris (University of Tartu, University of Tartu. Estonian Genome Center) ; Aung, Tin (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Azizi, Fereidoun (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Endocrine Research Center) ; Bentley, Amy R. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Boeing, Heiner (German Institute of Human Nutrition Potsdam-Rehbruecke. Department of Epidemiology) ; Boerwinkle, Eric (UTHealth School of Public Health, University of Texas. Health Science Center at Houston) ; Borja, Judith B. (USC-Office of Population Studies Foundation, Inc., Department of Nutrition and Dietetics, Talamban, University of San Carlos) ; de Borst, Gert J. (University Medical Center Utrecht) ; Bottinger, Erwin P. (Hasso Plattner Institute, Universität Potsdam. Digital Health Center) ; Broer, Linda (Erasmus University Medical Center. Department of Internal Medicine) ; Campbell, Harry (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Chanock, Stephen (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Chee, Miao-Li (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Chen, Guanjie (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Chen, Yii Der Ida (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Chen, Zhengming (University of Oxford. Nuffield Department of Population Health) ; Chiu, Yen-Feng (Institute of Population Health Sciences, National Health Research Institutes) ; Cocca, Massimiliano (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; Collins, Francis S. (National Human Genome Research Institute, National Institutes of Health) ; Concas, Maria Pina (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; Corley, Janie (University of Edinburgh. Department of Psychology) ; Cugliari, Giovanni (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; van Dam, Rob M. (Harvard T.H. Chan School of Public Health. Department of Nutrition) ; Damulina, Anna (Medical University of Graz. Clinical Division of Neurogeriatrics, Department of Neurology) ; Daneshpour, Maryam S. (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Day, Felix R. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Delgado, Graciela E. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Dhana, Klodian (Rush University Medical Center. Department of Internal Medicine) ; Doney, Alexander S. F. (Molecular and Clinical Medicine, University of Dundee. MEMO Research) ; Dörr, Marcus (DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475 Germany) ; Doumatey, Ayo P. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Dzimiri, Nduna (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ; Ebenesersdóttir, S. Sunna (University of Iceland. Department of Anthropology) ; Elliott, Joshua (Imperial College London. Department of Epidemiology and Biostatistics) ; Elliott, Paul (Health Data Research UK - London, London, England) ; Ewert, Ralf (University Medicine Greifswald. Department of Internal Medicine B) ; Felix, Janine F. (Erasmus University Medical Center. Department of Pediatrics) ; Fischer, Krista (University of Tartu, University of Tartu. Estonian Genome Center) ; Freedman, Barry I (Wake Forest School of Medicine. Section on Nephrology, Department of Internal Medicine) ; Girotto, Giorgia (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Goel, Anuj (University of Oxford. Division of Cardiovascular Medicine, Radcliffe Department of Medicine) ; Gögele, Martin (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Goodarzi, Mark O. (Cedars-Sinai Medical Center. Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine) ; Graff, Mariaelisa (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Granot-Hershkovitz, Einat (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Grodstein, Francine (Harvard T.H. Chan School of Public Health. Department of Epidemiology) ; Guarrera, Simonetta (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; Gudbjartsson, Daniel F. (School of Engineering and Natural Sciences, University of Iceland) ; Guity, Kamran (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Gunnarsson, Bjarni (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Guo, Yu (Chinese Academy of Medical Sciences) ; Hagenaars, Saskia P. (Institute of Psychiatry, Psychology & Neuroscience, King's College London. Social, Genetic and Developmental Psychiatry Centre) ; Haiman, Christopher A. (Keck School of Medicine, University of Southern California. Department of Preventive Medicine) ; Halevy, Avner (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Harris, Tamara B. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Hedayati, Mehdi (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; van Heel, David A. (Blizard Institute, Queen Mary University of London) ; Hirata, Makoto (Institute of Medical Science, The University of Tokyo. Laboratory of Genome Technology) ; Höfer, Imo (University Medical Center Utrecht) ; Hsiung, Chao Agnes (Institute of Population Health Sciences, National Health Research Institutes) ; Huang, Jinyan (Shanghai Institute of Hematology, State Key Laboratory Of Medical Genomics, Rui-jin Hospital, Shanghai Jiao Tong University School of Medicine) ; Hung, Yi-Jen (National Defense Medical Center. School of Medicine) ; Ikram, M. Arfan (Erasmus University Medical Center. Department of Epidemiology) ; Jagadeesan, Anuradha (University of Iceland. Department of Anthropology) ; Jousilahti, Pekka (National Institute for Health and Welfare. Unit of Public Health Promotion) ; Kamatani, Yoichiro (Kyoto University Graduate School of Medicine. Center for Genomic Medicine) ; Kanai, Masahiro (Harvard Medical School. Department of Biomedical Informatics) ; Kerrison, Nicola D. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Kessler, Thorsten (Klinik für Herz- und Kreislauferkrankungen, Technische Universität München. Deutsches Herzzentrum München) ; Khaw, Kay-Tee (University of Cambridge. Department of Public Health and Primary Care) ; Khor, Chiea Chuen (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; de Kleijn, Dominique P. V (University Medical Center Utrecht) ; Koh, Woon-Puay (Duke-NUS Medical School. Health Services and Systems Research) ; Kolcic, Ivana (University of Split. Centre for Global Health, Faculty of Medicine) ; Kraft, Peter (Harvard T.H. Chan School of Public Health. Department of Nutrition) ; Krämer, Bernhard K. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Kutalik, Zoltán (Swiss Institute of Bioinformatics) ; Kuusisto, Johanna (Kuopio University Hospital ( Finlàndia)) ; Langenberg, Claudia (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Launer, Lenore J. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Lawlor, Deborah A. (Population Health Science, Bristol Medical School, Bristol, BS8 2BY UK) ; Lee, I-Te (Chung Shan Medical University, Taichung, Taiwan. School of Medicine) ; Lee, Wen-Jane (Taichung Veterans General Hospital. Department of Medical Research) ; Lerch, Markus M. (University Medicine Greifswald. Department of Internal Medicine A) ; Li, Liming (Peking University Health Science Centre, Peking University. Department of Epidemiology and Biostatistics) ; Liu, Jianjun (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; Loh, Marie (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Biochemistry) ; London, Stephanie J. (National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services) ; Loomis, Stephanie (Johns Hopkins Bloomberg School of Public Health. Department of Epidemiology) ; Lu, Yingchang (Icahn School of Medicine at Mount Sinai (Nova York, Estats Units d'Amèrica)) ; Luan, Jian'an (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Mägi, Reedik (University of Tartu, University of Tartu. Estonian Genome Center) ; Manichaikul, Ani W. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Manunta, Paolo (Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Università Vita Salute San Raffaele, Milano, 20132 Italy) ; Másson, Gísli (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Matoba, Nana (Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Mei, Xue W. (University of Oxford. Nuffield Department of Population Health) ; Meisinger, Christa (Helmholtz Zentrum München, Independent Research Group Clinical Epidemiology, Neuherberg, 85764 Germany) ; Meitinger, Thomas (DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance) ; Mezzavilla, Massimo (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Milani, Lili (Institute of Genomics, University of Tartu. Estonian Genome Center) ; Millwood, Iona Y (University of Oxford. Nuffield Department of Population Health) ; Momozawa, Yukihide (Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Moore, Amy (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Morange, Pierre-Emmanuel (Aix-Marseille University. INSERM UMR_S 1263, Center for CardioVascular and Nutrition research (C2VN)) ; Moreno-Macías, Hortensia (Universidad Autónoma Metropolitana. Departamento de Economía) ; Mori, Trevor A. (The University of Western Australia. Medical School) ; Morrison, Alanna C. (The University of Texas Health Science Center at Houston, School of Public Health, Department of Epidemiology, Human Genetics and Environmental Sciences) ; Muka, Taulant (Institute of Social and Preventive Medicine (ISPM), University of Bern) ; Murakami, Yoshinori (Institute of Medical Science, The University of Tokyo. Division of Molecular Pathology) ; Murray, Alison D. (The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen) ; de Mutsert, Renée (Leiden University Medical Center. Department of Clinical Epidemiology) ; Mychaleckyj, Josyf C. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Nalls, Mike A. (Data Tecnica International LLC, Glen Echo, MD 20812 USA) ; Nauck, Matthias (Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald) ; Neville, Matt J. (Oxford University Hospitals Trust. Oxford NIHR Biomedical Research Centre) ; Nolte, Ilja M. (University of Groningen, University Medical Center Groningen. Department of Epidemiology) ; Ong, Ken K. (University of Cambridge School of Clinical Medicine. Department of Paediatrics) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Padmanabhan, Sandosh (Institute of Cardiovascular and Medical Sciences, University of Glasgow) ; Pálsson, Gunnar (deCODE genetics/Amgen Inc., Reykjavik, Iceland) ; Pankow, James S. (School of Public Health, University of Minnesota. Division of Epidemiology & Community Health) ; Pattaro, Cristian (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Pattie, Alison (University of Edinburgh. Department of Psychology) ; Polasek, Ozren (Gen-info Ltd, Zagreb, Croatia, Zagreb, Select a Province Croatia) ; Poulter, Neil (Imperial College London, London. Imperial Clinical Trials Unit) ; Pramstaller, Peter P. (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Quintana-Murci, Lluis (Institut Pasteur. Center of Bioinformatics, Biostatistics and Integrative Biology) ; Räikkönen, Katri (University of Helsinki, University of Helsinki. Department of Psychology and Logopedics, Faculty of Medicine) ; Ralhan, Sarju (Hero Heart Institute and Dyanand Medical College and Hospital) ; Rao, Dabeeru C. (Washington University School of Medicine. Division of Biostatistics) ; van Rheenen, Wouter (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Rich, Stephen S. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Ridker, Paul M. (Harvard Medical School) ; Rietveld, Cornelius A. (Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus University Rotterdam) ; Robino, Antonietta (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; van Rooij, Frank J. A. (Erasmus University Medical Center. Department of Epidemiology) ; Ruggiero, Daniela (IRCCS Neuromed) ; Saba, Yasaman (Medical University of Graz. Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry) ; Sabanayagam, Charumathi (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Sala, Cinzia Felicita (San Raffaele Research Institute, Milano, Italy) ; Salomaa, Veikko (National Institute for Health and Welfare. Department of Public Health Solutions) ; Sandow, Kevin (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Schmidt, Helena (Medical University of Graz. Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry) ; Scott, Laura J. (University of Michigan. Department of Biostatistics, and Center for Statistical Genetics) ; Scott, William R. (Imperial College London. Department of Epidemiology and Biostatistics) ; Sedaghati-Khayat, Bahareh (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Sennblad, Bengt (National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala. Dept of Cell and Molecular Biology) ; van Setten, Jessica (University Medical Center Utrecht) ; Sever, Peter J. (International Centre for Circulatory Health, Imperial College London) ; Sheu, Wayne H-H (Institute of Medical Technology, National Chung-Hsing University) ; Shi, Yuan (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Shrestha, Smeeta (School of Basic and Applied Sciences, Dayananda Sagar University, Bangalore, Karnataka 560078 India) ; Shukla, Sharvari Rahul (Symbiosis Statistical Institute, Symbiosis International University) ; Sigurdsson, Jon K. (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Sikka, Timo Tonis (University of Tartu, University of Tartu. Estonian Genome Center) ; Singh, Jai Rup (Panjab University) ; Smith, Blair H. (Ninewells Hospital and Medical School, University of Dundee. Division of Population Health Sciences) ; Stančáková, Alena (Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland) ; Stanton, Alice (RCSI Molecular & Cellular Therapeutics (MCT), Royal College of Surgeons in Ireland, RCSI Education & Research Centre, Beaumont Hospital, Dublin 9, Ireland) ; Starr, John M. (University of Edinburgh. Alzheimer Scotland Dementia Research Centre) ; Stefansdottir, Lilja (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Straker, Leon (School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University) ; Sulem, Patrick (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Sveinbjornsson, Gardar (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Swertz, Morris A. (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, 9700 RB The Netherlands) ; Taylor, Adele M. (University of Edinburgh. Department of Psychology) ; Taylor, Kent D. (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Terzikhan, Natalie (Ghent University Hospital. (Bèlgica)) ; Tham, Yih-Chung (Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore) ; Thorleifsson, Gudmar (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Thorsteinsdottir, Unnur (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Tillander, Annika (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Tracy, Russell P. (University of Vermont. Department of Pathology) ; Tusié-Luna, Teresa (Unidad De Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ; Tzoulaki, Ioanna (University of Ioannina Medical School. Department of Hygiene and Epidemiology) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy) ; Vangipurapu, Jagadish (Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland) ; Veldink, Jan (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Vitart, Veronique (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Völker, Uwe (DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475 Germany) ; Vuoksimaa, Eero (Institute for Molecular Medicine Finland (FIMM), University of Helsinki) ; Wakil, Salma M. (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ; Waldenberger, Melanie (Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764 Germany) ; Wander, Gurpreet S. (Hero DMC Heart Institute, Dayanand Medical College & Hospital. Department of Cardiology) ; Wang, Ya Xing (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab) ; Wareham, Nicholas J. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Wild, Sarah (Usher Institute of Population Health and Informatics, University of Edinburgh. Centre for Population Health Sciences) ; Yajnik, Chittaranjan S. (Diabetes Unit, K.E.M. Hospital Research Centre) ; Yuan, Jian-Min (Graduate School of Public Health, University of Pittsburgh. Department of Epidemiology) ; Zeng, Lingyao (Klinik für Herz- und Kreislauferkrankungen, Technische Universität München. Deutsches Herzzentrum München) ; Zhang, Liang (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Zhou, Jie (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Amin, Najaf (Erasmus University Medical Center. Department of Epidemiology) ; Asselbergs, Folkert W. (Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London) ; Bakker, Stephan J. L. (Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, 9713GZ The Netherlands) ; Becker, Diane M. (Johns Hopkins University School of Medicine. Department of Medicine, GeneSTAR Research Program) ; Lehne, Benjamin (Imperial College London. Department of Epidemiology and Biostatistics) ; Bennett, David A. (Rush University Medical Center. Department of Neurological Sciences) ; van den Berg, Leonard H. (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Berndt, Sonja (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Bharadwaj, Dwaipayan (School of Biotechnology, Jawaharlal Nehru University. Systems Genomics Laboratory) ; Bielak, Lawrence F. (University of Michigan. Department of Epidemiology, School of Public Health) ; Bochud, Murielle (University of Lausanne. Center for Primary Care and Public Health (Unisanté)) ; Boehnke, Michael (University of Michigan. Department of Biostatistics, and Center for Statistical Genetics) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Bradfield, Jonathan Paul (Quantinuum Research LLC, San Diego, CA 92101 USA) ; Brody, Jennifer A. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Campbell, Archie (Institute of Genetics & Molecular Medicine, University of Edinburgh. Centre for Genomic & Experimental Medicine) ; Carmi, Shai (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Caulfield, Mark (William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London. Department of Clinical Pharmacology) ; Cesarini, David (Research Institute for Industrial Economics (IFN)) ; Chambers, John C. (Imperial College Healthcare NHS Trust, London) ; Chandak, Giriraj Ratan (CSIR-Centre for Cellular and Molecular Biology. Genomic Research on Complex diseases (GRC Group)) ; Cheng, Ching-Yu (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Ciullo, Marina (IRCCS Neuromed) ; Cornelis, Marilyn (Northwestern University Feinberg School of Medicine. Department of Preventive Medicine) ; Cusi, Daniele (Bio4Dreams Scientific Unit, Bio4Dreams SRL, Bio4Dreams - business nursery for life sciences, Milano, 20121 Italy) ; Smith, George Davey (Population Health Science, Bristol Medical School, Bristol, BS8 2BY UK) ; Deary, Ian J. (University of Edinburgh. Department of Psychology) ; Dorajoo, Rajkumar (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; van Duijn, Cornelia M. (Erasmus University Medical Center. Department of Epidemiology) ; Ellinghaus, David (Christian-Albrechts-University of Kiel. Institute of Clinical Molecular Biology) ; Erdmann, Jeanette (University of Lübeck. Institute for Cardiogenetics) ; Eriksson, Johan G. (Vasa Central Hospital) ; Evangelou, Evangelos (University of Ioannina Medical School. Department of Hygiene and Epidemiology) ; Evans, Michele K. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Faul, Jessica D. (University of Michigan. Institute for Social Research) ; Feenstra, Bjarke (Statens Serum Institut. Department of Epidemiology Research) ; Feitosa, Mary (Washington University School of Medicine. Division of Statistical Genomics, Department of Genetics) ; Foisy, Sylvain (Montreal Heart Institute) ; Franke, Andre (Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel) ; Friedlander, Yechiel (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Gasparini, Paolo (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Gonzalez, Clicerio (Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica) ; Goyette, Philippe (Montreal Heart Institute) ; Grant, Struan F. A. (Perelman School of Medicine, University of Pennsylvania. Department of Pediatrics) ; Griffiths, Lyn R. (Institute of Health and Biomedical Innovation, Queensland University of Technology. Genomics Research Centre, School of Biomedical Sciences) ; Groop, Leif (Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, Sweden) ; Gudnason, Vilmundur (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Gyllensten, Ulf (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Hakonarson, Hakon (University of Pennsylvania. Perelman School of Medicine) ; Hamsten, Anders (Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Stockholm, 171 76 Sweden) ; van der Harst, Pim (University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands) ; Heng, Chew-Kiat (Khoo Teck Puat - National University Children's Medical Institute, National University Health System) ; Hicks, Andrew A. (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Hochner, Hagit (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Huikuri, Heikki (Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital) ; Hunt, Steven C. (University of Utah School of Medicine. Division of Epidemiology, Department of Internal Medicine) ; Jaddoe, Vincent W. V (Erasmus University Medical Center. Department of Pediatrics) ; De Jager, Philip L. (Cell Circuits Program, Broad Institute) ; Johannesson, Magnus (Stockholm School of Economics. Department of Economics) ; Johansson, Åsa (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Jonas, Jost B. (University of Heidelberg) ; Jukema, J. Wouter (Leiden University Medical Center. Department of Cardiology) ; Junttila, Juhani (Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital) ; Kaprio, Jaakko (University of Helsinki. Department of Public Health) ; Kardia, Sharon L. R. (University of Michigan. Department of Epidemiology, School of Public Health) ; Karpe, Fredrik (Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital) ; Kumari, Meena (Institute for Social and Economic Research, University of Essex) ; Laakso, Markku (Kuopio University Hospital ( Finlàndia)) ; van der Laan, Sander W. (University Medical Center Utrecht) ; Lahti, Jari (University of Helsinki, University of Helsinki. Helsinki Collegium for Advanced Studies) ; Laudes, Matthias (Universitätsklinikum Schleswig-Holstein (Alemanya)) ; Lea, Rodney A. (Institute of Health and Biomedical Innovation, Queensland University of Technology. Genomics Research Centre, School of Biomedical Sciences) ; Lieb, Wolfgang (Institute of Epidemiology and PopGen Biobank, University of Kiel) ; Lumley, Thomas (University of Auckland. Department of Statistics) ; Martin, Nicholas G. (QIMR Berghofer Institute of Medical Research) ; März, Winfried (Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany) ; Matullo, Giuseppe (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; McCarthy, Mark I (Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital) ; Medland, Sarah Elizabeth (QIMR Berghofer Institute of Medical Research) ; Merriman, Tony R. (University of Otago. Department of Biochemistry) ; Metspalu, Andres (University of Tartu, University of Tartu. Estonian Genome Center) ; Meyer, Brian F. (King Faisal Specialist Hospital and Research Centre. Department of Genetics) ; Mohlke, Karen L. (University of North Carolina. Department of Genetics) ; Montgomery, Grant W. (Institute for Molecular Bioscience, The University of Queensland) ; Mook-Kanamori, Dennis (Leiden University Medical Center. Department of Public Health and Primary Care) ; Munroe, Patricia B. (Queen Mary University of London. Department of Clinical Pharmacology) ; North, Kari E. (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Nyholt, Dale R. (School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology) ; O'connell, Jeffery R. (University of Maryland, School of Medicine. Program for Personalized and Genomic Medicine, Department of Medicine) ; Ober, Carole (University of Chicago. Department of Human Genetics) ; Oldehinkel, Albertine J. (Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen. Department of Psychiatry) ; Palmas, Walter (Columbia University Medical Center. Department of Medicine) ; Palmer, Colin (Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, The School of Medicine, University of Dundee) ; Pasterkamp, Gerard G. (University Medical Center Utrecht) ; Patin, Etienne (Institut Pasteur. Center of Bioinformatics, Biostatistics and Integrative Biology) ; Pennell, Craig E. (The University of Western Australia. Division of Obstetrics and Gynaecology) ; Pérusse, Louis (Institute of Nutrition and Functional Foods, Laval University) ; Peyser, Patricia A. (University of Michigan. Department of Epidemiology, School of Public Health) ; Pirastu, Mario (Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy) ; Polderman, Tinca J. C. (Vrije Universiteit Amsterdam. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research) ; Porteous, David J. (Institute of Genetics & Molecular Medicine, University of Edinburgh. Centre for Genomic & Experimental Medicine) ; Posthuma, Danielle (Amsterdam Universitair Medische Centra (Amsterdam, Països Baixos)) ; Psaty, Bruce M. (Kaiser Permanente Washington Health Research Institute) ; Rioux, John D. (Université de Montréal. Department of Medicine, Faculty of Medicine) ; Rivadeneira, Fernando (The Generation R Study Group, Erasmus University Medical Center) ; Rotimi, Charles (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Rotter, Jerome I (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Rudan, Igor (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Den Ruijter, Hester M. (University Medical Center Utrecht) ; Sanghera, Dharambir K. (Oklahoma Center for Neuroscience, Oklahoma City, USA) ; Sattar, Naveed (Institute of Cardiovascular and Medical Sciences, University of Glasgow) ; Schmidt, Reinhold (Medical University of Graz. Clinical Division of Neurogeriatrics, Department of Neurology) ; Schulze, Matthias B. (Institute of Nutritional Sciences, University of Potsdam) ; Schunkert, Heribert (Deutsches Zentrum für Herz- und Kreislauferkrankungen (DZHK), Munich Heart Alliance, Munich, 80636 Germany) ; Scott, Robert A. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Shuldiner, Alan R. (Regeneron Pharmaceuticals, Inc. Regeneron Genetics Center) ; Sim, Xueling (National University of Singapore, Singapore. Saw Swee Hock School of Public Health) ; Small, Neil (University of Bradford. Faculty of Health Studies) ; Smith, Jennifer A. (University of Michigan. Institute for Social Research) ; Sotoodehnia, Nona (University of Washington) ; Tai, E-Shyong (National University of Singapore. Duke-NUS Medical School) ; Teumer, Alexander (University Medicine Greifswald) ; Timpson, Nicholas J. (University of Bristol) ; Toniolo, Daniela (San Raffaele Research Institute, Milano, Italy) ; Tregouet, David-Alexandre (Sorbonne Universités) ; Tuomi, Tiinamaija (University of Helsinki. Research Program of Diabetes and Endocrinology) ; Vollenweider, Peter (Lausanne University Hospital) ; Wang, Carol A. (The University of Western Australia. Division of Obstetrics and Gynaecology) ; Weir, David R. (University of Michigan. Institute for Social Research) ; Whitfield, John B. (QIMR Berghofer Institute of Medical Research) ; Wijmenga, Cisca (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, RB The Netherlands) ; Wong, Tien-Yin (Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore) ; Wright, John (Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford, UK) ; Yang, Jingyun (Rush University Medical Center. Department of Neurological Sciences) ; Yu, Lei (Rush University Medical Center. Department of Neurological Sciences) ; Zemel, Babette S. (Children's Hospital of Philadelphia (Pennsilvània)) ; Zonderman, Alan B. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Perola, Markus (National Institute for Health and Welfare. Unit of Genomics and Biomarkers) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia).) ; Uitterlinden, André G. (The Generation R Study Group, Erasmus University Medical Center) ; Kooner, Jaspal S. (Imperial College London) ; Chasman, Daniel I (Harvard Medical School) ; Loos, Ruth J. F. (The Icahn School of Medicine at Mount Sinai. The Mindich Child Health and Development Institute) ; Franceschini, Nora (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Franke, Lude (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, The Netherlands) ; Haley, Chris S. (Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland) ; Hayward, Caroline (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Walters, Robin G. (University of Oxford. Nuffield Department of Population Health) ; Perry, John R. B. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Esko, Tōnu (Broad Institute, Broad Institute. Program in Medical and Population Genetics) ; Helgason, Agnar (University of Iceland. Department of Anthropology) ; Stefansson, Kari (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Joshi, Peter K. (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Kubo, Michiaki (Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Wilson, James F.. (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Universitat Autònoma de Barcelona
In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. [...]
2019 - 10.1038/s41467-019-12283-6
Nature communications, Vol. 10 (october 2019)  
6.
14 p, 1.9 MB The FANCM :p.Arg658* truncating variant is associated with risk of triple-negative breast cancer / Figlioli, Gisella (The FIRC Institute for Molecular Oncology) ; Bogliolo, Massimo (Institut d'Investigació Biomèdica Sant Pau) ; Catucci, Irene (The FIRC Institute for Molecular Oncology) ; Caleca, Laura (Istituto Nazionale dei Tumori, Department of Research) ; Viz Lasheras, Sandra (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Pujol, Roser (Institut d'Investigació Biomèdica Sant Pau) ; Kiiski, Johanna I. (University of Helsinki, Department of Obstetrics and Gynecology) ; Muranen, Taru A. (University of Helsinki, Department of Obstetrics and Gynecology) ; Barnes, Daniel R. (University of Cambridge, Department of Public Health and Primary Care) ; Dennis, Joe (University of Cambridge, Department of Public Health and Primary Care) ; Michailidou, Kyriaki (The Cyprus Institute of Neurology & Genetics, Department of Electron Microscopy) ; Bolla, Manjeet K. (University of Cambridge, Department of Public Health and Primary Care) ; Leslie, Goska (University of Cambridge, Department of Public Health and Primary Care) ; Aalfs, Cora M. (Amsterdam UMC, Department of Clinical Genetics) ; Adank, Muriel A. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Adlard, Julian (Chapel Allerton Hospital) ; Agata, Simona (Veneto Institute of Oncology (Pàdua, Itàlia)) ; Cadoo, Karen (Memorial Sloan Kettering Cancer Center) ; Agnarsson, Bjarni A. (University of Iceland, School of Medicine) ; Ahearn, Thomas (National Cancer Institute) ; Aittomäki, Kristiina (University of Helsinki, Department of Clinical Genetics) ; Ambrosone, Christine B. (Roswell Park Cancer Institute) ; Andrews, Lesley (Nelune Comprehensive Cancer Care Centre) ; Anton-Culver, Hoda (University of California Irvine, Department of Epidemiology) ; Antonenkova, Natalia N. (N.N. Alexandrov Research Institute of Oncology and Medical Radiology) ; Arndt, Volker (German Cancer Research Center) ; Arnold, Norbert (University Hospital of Schleswig-Holstein, Department of Gynaecology and Obstetrics) ; Aronson, Kristan J. (Queen's University, Department of Public Health Sciences) ; Arun, Banu K. (University of Texas, Department of Breast Medical Oncology) ; Asseryanis, Ella (Medical University of Vienna, Dept of OB/GYN and Comprehensive Cancer Center) ; Auber, Bernd (Institute of Human Genetics) ; Auvinen, Päivi (University of Eastern Finland, Translational Cancer Research Area) ; Azzollini, Jacopo (Fondazione Istituto Nazionale dei Tumori di Milano, Department of Medical Oncology and Hematology) ; Balmaña Gelpí, Judith (Hospital Universitari Vall d'Hebron) ; Barkardottir, Rosa B. (University of Iceland) ; Barrowdale, Daniel (University of Cambridge, Department of Public Health and Primary Care) ; Barwell, Julian (Leicester General Hospital (Leicester, Regne Unit)) ; Beane-Freeman, Laura (National Cancer Institute) ; Beauparlant, Charles Joly (Centre Hospitalier Universitaire de Québec - Université Laval) ; Beckmann, Matthias W. (Friedrich-Alexander-University Erlangen-Nuremberg, Department of Gynecology and Obstetrics) ; Behrens, Sabine (German Cancer Research Center) ; Benitez, Javier (Centro Nacional de Investigaciones Oncológicas) ; Berger, Raanan (Chaim Sheba Medical Center. The Institute of Oncology) ; Bermisheva, Marina (Institute of Biochemistry and Genetics) ; Blanco, Amie M. (University of California San Francisco) ; Blomqvist, Carl (Örebro University Hospital, Department of Oncology) ; Bogdanova, Natalia V. (Hannover Medical School) ; Bojesen, Anders (Aarhus University Hospital (Aarhus, Dinamarca)) ; Bojesen, Stig E. (University of Copenhagen) ; Bonanni, Bernardo (IEO, European Institute of Oncology) ; Borg, Åke (Skåne University Hospital (Suècia)) ; Brady, Angela F. (London North West University Hospitals) ; Brauch, Hiltrud (German Cancer Research Center) ; Brenner, Hermann (German Cancer Research Center) ; Brüning, Thomas (Institute of the Ruhr University Bochum) ; Burwinkel, Barbara (University of Heidelberg) ; Buys, Saundra (Huntsman Cancer Institute, Department of Medicine) ; Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Caliebe, Almuth (Universitätsklinikum Schleswig-Holstein (Alemanya)) ; Caligo, Maria (University Hospital of Pisa (Pisa, Itàlia)) ; Campa, Daniele (University of Pisa, Department of Biology) ; Campbell, Ian (The University of Melbourne, Department of Oncology) ; Canzian, Federico (German Cancer Research Center) ; Castelao, Jose E. (Instituto de Investigación Sanitaria Galicia Sur) ; Chang-Claude, Jenny (University Medical Center Hamburg-Eppendorf) ; Chanock, Stephen J. (National Cancer Institute) ; Claes, Kathleen (Ghent University, Centre for Medical Genetics) ; Clarke, Christine L. (University of Sydney, Westmead Institute for Medical Research) ; Collavoli, Anita (University Hospital of Pisa (Pisa, Itàlia)) ; Conner, Thomas A. (Huntsman Cancer Institute (Salt Lake City, Estats Units d'Amèrica)) ; Cox, David G. (Cancer Research Center of Lyon) ; Cybulski, Cezary (Pomeranian Medical University, Department of Genetics and Pathology) ; Czene, Kamila (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Daly, Mary B. (Fox Chase Cancer Center, Department of Clinical Genetics) ; De la Hoya, Miguel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Devilee, Peter (Leiden University Medical Center, Department of Human Genetics) ; Diez, Orland (Hospital Universitari Vall d'Hebron) ; Ding, Yuan Chun (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica). Department of Population Sciences) ; Dite, Gillian S. (The University of Melbourne) ; Ditsch, Nina (Ludwig Maximilian University of Munich, Department of Gynecology and Obstetrics) ; Domchek, Susan M. (Perelman School of Medicine at the University of Pennsylvania, Department of Medicine) ; Dorfling, Cecilia M. (University of Pretoria, Department of Genetics) ; dos-Santos-Silva, Isabel (London School of Hygiene and Tropical Medicine, Department of Non-Communicable Disease Epidemiology) ; Durda, Katarzyna (Pomeranian Medical University, Department of Genetics and Pathology) ; Dwek, Miriam (University of Westminster, Department of Biomedical Sciences) ; Eccles, Diana M. (University of Southampton, Cancer Sciences Academic Unit) ; Ekici, Arif B. (Friedrich-Alexander University Erlangen-Nuremberg) ; Eliassen, A. Heather (Harvard T.H. Chan School of Public Health, Department of Epidemiology) ; Ellberg, Carolina (Lund University, Department of Cancer Epidemiology) ; Eriksson, Mikael (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Evans, D. Gareth (Manchester University NHS Foundation Trust) ; Fasching, Peter A. (University of California at Los Angeles, Department of Medicine Division of Hematology and Oncology) ; Figueroa, Jonine (Cancer Research UK Edinburgh Centre) ; Flyger, Henrik (Copenhagen University Hospital) ; Foulkes, William D. (McGill University, Departments of Human Genetics and Oncology) ; Friebel, Tara M. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Friedman, Eitan (Tel Aviv University) ; Gabrielson, Marike (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Gaddam, Pragna (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ; Gago-Dominguez, Manuela (University of California San Diego) ; Gao, Chi (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Gapstur, Susan M. (American Cancer Society) ; Garber, Judy (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; García-Closas, Montserrat (National Cancer Institute) ; García-Sáenz, José A. (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Gaudet, Mia M. (American Cancer Society) ; Gayther, Simon A. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Giles, Graham G. (Monash University, Department of Epidemiology and Preventive Medicine) ; Glendon, Gord (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ; Godwin, Andrew K. (Kansas University Medical Center, Department of Pathology and Laboratory Medicine) ; Goldberg, Mark S. (McGill University) ; Goldgar, David E. (University of Utah School of Medicine, Department of Dermatology) ; Guénel, Pascal (University Paris-Sud, University Paris-Saclay) ; Gutierrez-Barrera, Angelica M. (University of Texas, Department of Breast Medical Oncology and Clinical Genetics Program) ; Haeberle, Lothar (University Hospital Erlangen (Alemanya)) ; Haiman, Christopher A. (University of Southern California, Department of Preventive Medicine) ; Håkansson, Niclas (Karolinska Institutet, Institute of Environmental Medicine) ; Hall, Per (Södersjukhuset, Department of Oncology) ; Hamann, Ute (German Cancer Research Center) ; Harrington, Patricia A. (University of Cambridge, Department of Oncology) ; Hein, Alexander (University Hospital Erlangen (Alemanya)) ; Heyworth, Jane (The University of Western Australia) ; Hillemanns, Peter (Hannover Medical School, Gynaecology Research Unit) ; Hollestelle, Antoinette (Erasmus MC Cancer Institute) ; Hopper, John L. (The University of Melbourne) ; Hosgood, H. Dean (Albert Einstein College of Medicine) ; Howell, Anthony (University of Manchester, Division of Cancer Sciences) ; Hu, Chunling (Mayo Clinic, Department of Laboratory Medicine and Pathology) ; Hulick, Peter J. (The University of Chicago Pritzker School of Medicine) ; Hunter, David J. (University of Oxford) ; Imyanitov, Evgeny N. (N.N. Petrov Institute of Oncology) ; Isaacs, Claudine (Georgetown University) ; Jakimovska, Milena (Macedonian Academy of Sciences and Arts) ; Jakubowska, Anna (Pomeranian Medical University) ; James, Paul (Peter MacCallum Cancer Center) ; Janavicius, Ramunas (State Research Institute Innovative Medicine Center) ; Janni, Wolfgang (University Hospital of Ulm (Alemanya)) ; John, Esther M. (Stanford University School of Medicine, Department of Medicine) ; Jones, Michael E. (The Institute of Cancer Research) ; Jung, Audrey (German Cancer Research Center) ; Kaaks, Rudolf (German Cancer Research Center) ; Karlan, Beth Y. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Khusnutdinova, Elza (Bashkir State Medical University, Department of Medical Genetics) ; Kitahara, Cari M. (National Cancer Institute) ; Konstantopoulou, Irene (National Centre for Scientific Research 'Demokritos') ; Koutros, Stella (National Cancer Institute) ; Kraft, Peter (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Lambrechts, Diether (University of Leuven, Department of Human Genetics) ; Lazaro, Conxi (Institut d'Investigació Biomèdica de Bellvitge) ; Le Marchand, Loic (University of Hawaii Cancer Center, Epidemiology Program) ; Lester, Jenny (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ; Lesueur, Fabienne (Mines ParisTech) ; Lilyquist, Jenna (Mayo Clinic, Department of Health Sciences Research) ; Loud, Jennifer T. (National Cancer Institute, Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics) ; Lu, Karen H. (University of Texas MD Anderson Cancer Center, Department of Gynecologic Oncology) ; Luben, Robert N. (University of Cambridge, Department of Public Health and Primary Care) ; Lubinski, Jan (Pomeranian Medical University, Department of Genetics and Pathology) ; Mannermaa, Arto (Kuopio University Hospital ( Finlàndia)) ; Manoochehri, Mehdi (German Cancer Research Center) ; Manoukian, Siranoush (Istituto Nazionale dei Tumori di Milano) ; Margolin, Sara (Karolinska Institutet, Department of Clinical Science and Education) ; Martens, John W. M. (Erasmus MC Cancer Institute) ; Maurer, Tabea (University Medical Center Hamburg-Eppendorf) ; Mavroudis, Dimitrios (University Hospital of Heraklion, Department of Medical Oncology) ; Mebirouk, Noura (Mines ParisTech) ; Meindl, Alfons (Ludwig Maximilian University of Munich, Department of Gynecology and Obstetrics) ; Menon, Usha (University College London) ; Miller, Austin (Roswell Park Cancer Institute) ; Montagna, Marco (Veneto Institute of Oncology (Pàdua, Itàlia)) ; Nathanson, Katherine L. (University of Pennsylvania, Department of Medicine) ; Neuhausen, Susan L. (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica). Department of Population Sciences) ; Newman, William G. (Manchester University NHS Foundation Trust) ; Nguyen-Dumont, Tu (The University of Melbourne, Department of Clinical Pathology) ; Nielsen, Finn Cilius (Copenhagen University Hospital) ; Nielsen, Sarah (The University of Chicago, Center for Clinical Cancer Genetics) ; Nikitina-Zake, Liene (Latvian Biomedical Research and Study Centre) ; Offit, Kenneth (Memorial Sloan-Kettering Cancer Center, Clinical Genetics Service, Department of Medicine) ; Olah, Edith (National Institute of Oncology, Department of Molecular Genetics) ; Olopade, Olufunmilayo I. (The University of Chicago) ; Olshan, Andrew F. (University of North Carolina at Chapel Hill, Department of Epidemiology) ; Olson, Janet E. (Mayo Clinic, Department of Health Sciences Research) ; Olsson, Håkan (Lund University, Department of Cancer Epidemiology, Clinical Sciences) ; Osorio, Ana (Spanish Network on Rare Diseases) ; Ottini, Laura (University La Sapienza, Department of Molecular Medicine) ; Peissel, Bernard (Istituto Nazionale dei Tumori di Milano) ; Peixoto, Ana (Portuguese Oncology Institute, Department of Genetics) ; Peto, Julian (London School of Hygiene and Tropical Medicine, Department of Non-Communicable Disease Epidemiology) ; Plaseska-Karanfilska, Dijana (Macedonian Academy of Sciences and Arts) ; Pocza, Timea (National Institute of Oncology, Department of Molecular Genetics) ; Presneau, Nadege (University of Westminster, Department of Biomedical Sciences) ; Pujana, Miquel Angel (Institut d'Investigació Biomèdica de Bellvitge) ; Punie, Kevin (University Hospitals Leuven (Bèlgica)) ; Rack, Brigitte (University Hospital of Ulm (Alemanya)) ; Rantala, Johanna (Karolinska Institutet, Clinical Genetics) ; Rashid, Muhammad U. (Shaukat Khanum Memorial Cancer Hospital and Research Centre, Department of Basic Sciences) ; Rau-Murthy, Rohini (Memorial Sloan-Kettering Cancer Center, Department of Medicine) ; Rennert, Gad (Clalit National Cancer Control Center) ; Lejbkowicz, Flavio (Clalit National Cancer Control Center) ; Rhenius, Valerie (University of Cambridge. Centre for Cancer Genetic Epidemiology) ; Romero, Atocha (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Rookus, Matti A. (The Netherlands Cancer Institute, Department of Epidemiology) ; Ross, Eric A. (Fox Chase Cancer Center) ; Rossing, Maria (Copenhagen University Hospital) ; Rudaitis, Vilius (Vilnius University, Institute of Clinical Medicine) ; Ruebner, Matthias (University Hospital Erlangen. Friedrich-Alexander University Erlangen-Nuremberg, Department of Gynaecology and Obstetrics) ; Saloustros, Emmanouil (General University Hospital of Larissa (Grècia)) ; Sanden, Kristin (University of Wisconsin, Cancer Center at ProHealth Care) ; Santamariña, Marta (Instituto de Investigación Sanitaria de Santiago (IDIS)) ; Scheuner, Maren T. (University of California San Francisco, Cancer Genetics and Prevention Program) ; Schmutzler, Rita K. (University of Cologne, Center for Molecular Medicine Cologne) ; Schneider, Michael (University Hospital Erlangen (Alemanya)) ; Scott, Christopher (Mayo Clinic, Department of Health Sciences Research) ; Senter, Leigha (The Ohio State University, Department of Internal Medicine) ; Shah, Mitul (University of Cambridge, Department of Oncology) ; Sharma, Priyanka (University of Kansas Medical Center, Department of Internal Medicine) ; Shu, Xiao-Ou (Vanderbilt University School of Medicine, Department of Medicine) ; Simard, Jacques (Université Laval) ; Singer, Christian F. (Medical University of Vienna) ; Sohn, Christof (University of Heidelberg) ; Soucy, Penny (Université Laval) ; Southey, Melissa C. (The University of Melbourne, Department of Clinical Pathology) ; Spinelli, John J. (University of British Columbia, School of Population and Public Health) ; Steele, Linda (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica). Department of Population Sciences) ; Stoppa-Lyonnet, Dominique (Université Paris Descartes) ; Tapper, William J. (University of Southampton) ; Teixeira, Manuel R. (University of Porto) ; Terry, Mary Beth (Columbia University, Department of Epidemiology) ; Thomassen, Mads (Odense University Hospital (Dinamarca)) ; Thompson, Jennifer (NorthShore University HealthSystem, Center for Medical Genetics) ; Thull, Darcy L. (University of Pittsburgh School of Medicine, Department of Medicine) ; Tischkowitz, Marc (University of Cambridge, Department of Medical Genetics) ; Tollenaar, Rob A. E. M. (Leiden University Medical Center, Department of Surgery) ; Torres, Diana (Pontificia Universidad Javeriana) ; Troester, Melissa A. (University of North Carolina at Chapel Hill) ; Truong, Thérèse (University Paris-Sud) ; Tung, Nadine (Beth Israel Deaconess Medical Center, Department of Medical Oncology) ; Untch, Michael (Helios Clinics Berlin-Buch, Department of Gynecology and Obstetrics) ; Vachon, Celine M. (Mayo Clinic, Department of Health Sciences Research) ; van Rensburg, Elizabeth J. (University of Pretoria, Department of Genetics) ; van Veen, Elke M. (Manchester University NHS Foundation Trust) ; Vega, Ana (Instituto de Investigación Sanitaria de Santiago (IDIS)) ; Viel, Alessandra (Centro di Riferimento Oncologico di Aviano) ; Wappenschmidt, Barbara (University of Cologne, Center for Molecular Medicine Cologne) ; Weitzel, Jeffrey N. (City of Hope, Clinical Cancer Genetics) ; Wendt, Camilla (Karolinska Institutet (Estocolm, Suècia)) ; Wieme, Greet (Ghent University, Centre for Medical Genetics) ; Wolk, Alicja (Uppsala University, Department of Surgical Sciences) ; Yang, Xiaohong R. (National Cancer Institute) ; Zheng, Wei (Vanderbilt University School of Medicine) ; Ziogas, Argyrios (University of California Irvine, Department of Epidemiology) ; Zorn, Kristin K. (University of Pittsburgh School of Medicine) ; Dunning, Alison M. (University of Cambridge, Department of Oncology) ; Lush, Michael (University of Cambridge, Department of Public Health and Primary Care) ; Wang, Qin (University of Cambridge, Department of Public Health and Primary Care) ; McGuffog, Lesley (University of Cambridge, Department of Public Health and Primary Care) ; Parsons, Michael T. (QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology) ; Pharoah, Paul D. P. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ; Fostira, Florentia (National Centre for Scientific Research 'Demokritos') ; Toland, Amanda E. (The Ohio State University, Department of Cancer Biology and Genetics) ; Andrulis, Irene L. (University of Toronto, Department of Molecular Genetics) ; Ramus, Susan J. (The Kinghorn Cancer Centre, Garvan Institute of Medical Research) ; Swerdlow, Anthony J. (The Institute of Cancer Research) ; Greene, Mark H. (National Cancer Institute, Clinical Genetics Branch) ; Chung, Wendy (Columbia University, Departments of Pediatrics and Medicine) ; Milne, Roger L. (Monash University) ; Chenevix-Trench, Georgia (QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology) ; Dörk, Thilo (Hannover Medical School) ; Schmidt, Marjanka K. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Easton, Douglas F. (University of Cambridge, Department of Oncology) ; Radice, Paolo (Istituto Nazionale dei Tumori) ; Hahnen, Eric (University of Cologne) ; Antoniou, Antonis C. (University of Cambridge, Department of Public Health and Primary Care) ; Couch, Fergus J. (Mayo Clinic, Department of Laboratory Medicine and Pathology) ; Nevanlinna, Heli (University of Helsinki, Department of Obstetrics and Gynecology) ; Surrallés i Calonge, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Peterlongo, Paolo (The FIRC Institute for Molecular Oncology)
Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 are associated with breast cancer risk. [...]
2019 - 10.1038/s41523-019-0127-5
NPJ breast cancer, Vol. 5 (November 2019) , art. 38  
7.
11 p, 168.8 KB Genetic variants in CETP increase risk of intracerebral hemorrhage / Anderson, Christopher D. (Broad Institute of MIT and Harvard) ; Falcone, Guido J. (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Phuah, Chia-Ling (Broad Institute of MIT and Harvard) ; Radmanesh, Farid (Broad Institute of MIT and Harvard) ; Brouwers, H. Bart (Broad Institute of MIT and Harvard) ; Battey, Thomas W. K. (Broad Institute of MIT and Harvard) ; Biffi, Alessandro (Division of Psychiatry, Department of Psychiatry, MGH) ; Peloso, Gina M. (Broad Institute of MIT and Harvard) ; Liu, Dajiang J. (Institute of Personalized Medicine, Penn State College of Medicine) ; Ayres, Alison M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Goldstein, Joshua N. (Department of Emergency Medicine, MGH) ; Viswanathan, Anand (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Greenberg, Steven M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Selim, Magdy (Beth Israel Deaconess Medical Center) ; Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ; Brown, Devin L. (University of Michigan Health System) ; Worrall, Bradford B. (University of Virginia Health System) ; Silliman, Scott L. (University of Florida College of Medicine) ; Tirschwell, David L. (University of Washington) ; Flaherty, Matthew L. (University of Cincinnati College of Medicine) ; Kraft, Peter (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Jagiella, Jeremiasz M. (Jagiellonian University Medical College) ; Schmidt, Helena (Medical University Graz) ; Hansen, Björn M. (Skåne University Hospital (Suècia)) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soriano Tàrraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; van Nieuwenhuizen, Koen M. (University Medical Center Utrecht) ; Klijn, Catharina J. M. (Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center) ; Rannikmae, Kristiina (University of Edinburgh) ; Samarasekera, Neshika (University of Edinburgh) ; Salman, Rustam Al-Shahi (University of Edinburgh) ; Sudlow, Catherine L. (University of Edinburgh) ; Deary, Ian J. (University of Edinburgh) ; Morotti, Andrea (Neurology Clinic, University of Brescia) ; Pezzini, Alessandro (Neurology Clinic, University of Brescia) ; Pera, Joanna (Jagiellonian University Medical College) ; Urbanik, Andrzej (Jagiellonian University Medical College) ; Pichler, Alexander (Medical University of Graz) ; Enzinger, Christian (Medical University of Graz) ; Norrving, Bo (Skåne University Hospital (Suècia)) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roquer González, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lindgren, Arne (Skåne University Hospital (Suècia)) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Schmidt, Reinhold (Medical University of Graz) ; Kidwell, Chelsea S. (University of Arizona) ; Kittner, Steven J. (Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine) ; Waddy, Salina P. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Langefeld, Carl D. (Wake Forest University) ; Abecasis, Goncalo (University of Michigan School of Public Health) ; Willer, Cristen J. (University of Michigan Medical School) ; Kathiresan, Sekar (Cardiovascular Disease Prevention Center, MGH) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Rosand, Jonathan (Broad Institute of MIT and Harvard) ; Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)
In observational epidemiologic studies, higher plasma high-density lipoprotein cholesterol (HDL-C) has been associated with increased risk of intracerebral hemorrhage (ICH). DNA sequence variants that decrease cholesteryl ester transfer protein (CETP) gene activity increase plasma HDL-C; as such, medicines that inhibit CETP and raise HDL-C are in clinical development. [...]
2016 - 10.1002/ana.24780
Annals of neurology, Vol. 80 (october 2016) , p. 730-740  
8.
16 p, 3.1 MB Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21 / Zhang, Mingfeng (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Wang, Zhaoming (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ; Obazee, Ofure (German Cancer Research Center (DKFZ)) ; Jia, Jinping (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Childs, Erica J. (Johns Hopkins School of Medicine. Department of Oncology) ; Hoskins, Jason (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Figlioli, Gisella (German Cancer Research Center (DKFZ)) ; Mocci, Evelina (Johns Hopkins School of Medicine. Department of Oncology) ; Collins, Irene (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Chung, Charles C. (Frederick National Laboratory for Cancer Research (Frederick, Estats Units d'Amèrica)) ; Hautman, Christopher (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Arslan, Alan A. (New York University Cancer Institute, New York, New York, USA) ; Beane-Freeman, Laura (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Bracci, Paige M. (University of California San Francisco. Department of Epidemiology and Biostatistics) ; Buring, Julie (Harvard Medical School) ; Duell, Eric J. (Institut d'Investigació Biomèdica de Bellvitge) ; Gallinger, Steven (Mount Sinai Hospital (Toronto, Canadà)) ; Giles, Graham G. (Monash University (Melbourne, Austràlia). Department of Epidemiology and Preventive Medicine) ; Goodman, Gary E. (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ; Goodman, Phyllis J. (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ; Kamineni, Aruna (Group Health Research Institute, Seattle, Washington, USA) ; Kolonel, Laurence N. (University of Hawaii Cancer Center. Cancer Epidemiology Program) ; Kulke, Matthew H. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Department of Medical Oncology) ; Malats, Núria (Centro Nacional de Investigaciones Oncológicas) ; Olson, Sara H. (Memorial Sloan Kettering Cancer Center) ; Sesso, Howard D. (Harvard Medical School) ; Visvanathan, Kala (Johns Hopkins Bloomberg School of Public Health) ; White, Emily (University of Washington. Department of Epidemiology) ; Zheng, Wei (Vanderbilt University Medical Center (Nashville, Estats Units d'Amèrica)) ; Abnet, Christian C. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Albanes, Demetrius (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Andreotti, Gabriella (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Brais, Lauren (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Department of Medical Oncology) ; Bueno-de-Mesquita, H. Bas (University of Malaya (Kuala Lumpur, Malàisia). Department of Social & Preventive Medicine) ; Basso, Daniela (University Hospital of Padova (Pàdua, Itàlia)) ; Berndt, Sonja (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Boutron-Ruault, Marie-Christine (IGR, F-94805, Villejuif, France) ; Bijlsma, Maarten F. (University of Amsterdam. Laboratory for Experimental Oncology and Radiobiology) ; Brenner, Hermann (German Cancer Research Center (DKFZ)) ; Burdette, Laurie (Frederick National Laboratory for Cancer Research (Frederick, Estats Units d'Amèrica)) ; Campa, Daniele (University of Pisa (Itàlia). Department of Biology) ; Caporaso, Neil E. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Capurso, Gabriele ('Sapienza' University of Rome. Digestive and Liver Disease Unit) ; Cavestro, Giulia Martina (Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy) ; Cotterchio, Michelle (University of Toronto. Dalla Lana School of Public Health) ; Costello, Eithne (University of Liverpool. Liverpool Pancreas Biomedical Research Unit) ; Elena, Joanne (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Boggi, Ugo (University Hospital of Pisa (Pisa, Itàlia)) ; Gaziano, J. Michael (Massachusetts Veteran's Epidemiology, Research, and Information Center, Geriatric Research Education and Clinical Center, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA) ; Gazouli, Maria (Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece) ; Giovannucci, Edward L. (Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA) ; Goggins, Michael (Johns Hopkins University. Department of Oncology) ; Gross, Myron (Laboratory of Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA) ; Haiman, Christopher A. (Preventive Medicine, University of Southern California, Los Angeles, California, USA) ; Hassan, Manal (Department of Gastrointestinal Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA) ; Helzlsouer, Kathy J. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Hu, Nan (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Hunter, David J. (Harvard Medical School, Boston, Massachusetts, USA) ; Iskierka-Jazdzewska, Elzbieta (Department of Hematology, Medical University of Łodz, Łodz, Poland) ; Jenab, Mazda (International Agency for Research on Cancer (IARC), Lyon, France) ; Kaaks, Rudolf (German Cancer Research Center (DKFZ)) ; Key, Timothy J. (Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom) ; Khaw, Kay-Tee (School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom) ; Klein, Eric A. (Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA) ; Kogevinas, M.. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Krogh, Vittorio (Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy) ; Kupcinskas, Juozas (Department of Gastroenterology, Lithuanian University of Health Sciences, Kaunas, Lithuania) ; Kurtz, Robert C. (Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA) ; Landi, Maria T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Landi, Stefano (Department of Biology, University of Pisa, Pisa, Italy) ; Marchand, Le Loic (Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA) ; Mambrini, Andrea (Oncology Department, ASL1 Massa Carrara, Massa Carrara, Italy) ; Mannisto, Satu (National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland) ; Milne, Roger L. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia) ; Neale, Rachel E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Oberg, Ann L. (Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA) ; Panico, Salvatore (Dipartimento di Medicina Clinica E Chirurgia, Federico II Univeristy, Naples, Italy) ; Patel, Alpa V. (Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA) ; Peeters, Petra H. M. (Imperial College London. Department of Epidemiology and Biostatistics) ; Peters, Ulrike (Department of Epidemiology, University of Washington, Seattle, Washington, USA) ; Pezzilli, Raffaele (Pancreas Unit, Department of Digestive Diseases and Internal Medicine, Sant'Orsola-Malpighi Hospital, Bologna, Italy) ; Porta, Miquel 1957- (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Purdue, Mark (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Quiros, J. Ramón (Public Health and Participation Directorate, Asturias, Spain) ; Riboli, Elio (Imperial College London. Department of Epidemiology and Biostatistics) ; Rothman, Nathaniel (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Scarpa, Aldo (University and Hospital Trust of Verona. ARC-Net Centre for Applied Research on Cancer) ; Scelo, Ghislaine (International Agency for Research on Cancer (IARC), Lyon, France) ; Shu, Xiao-Ou (Vanderbilt Epidemiology Center (Nashville, Estats Units d'Amèrica)) ; Silverman, Debra T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Soucek, Pavel (Laboratory of Pharmacogenomics, Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic) ; Strobel, Oliver (Heidelberg University Hospital (Alemanya)) ; Sund, Malin (Umeå University. Department of Surgical and Perioperative Sciences) ; Małecka-Panas, Ewa (Medical University of Łodz (Polònia)) ; Taylor, Philip R. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Tavano, Francesca (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ; Travis, Ruth C. (University of Oxford. Cancer Epidemiology Unit) ; Thornquist, Mark (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ; Tjønneland, Anne (Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark) ; Tobias, Geoffrey S. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Trichopoulos, Dimitrios (Hellenic Health Foundation, Athens, Greece) ; Vashist, Yogesh (University Hamburg-Eppendorf) ; Vodicka, Pavel (Academy of Sciences of the Czech Republic) ; Wactawski-Wende, Jean (University at Buffalo. Department of Social and Preventive Medicine) ; Wentzensen, Nicolas (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Yu, Herbert (University of Hawaii Cancer Center) ; Yu, Kai (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Zeleniuch-Jacquotte, Anne (New York University Cancer Institute) ; Kooperberg, Charles (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ; Risch, Harvey A. (Yale School of Public Health) ; Jacobs, Eric J. (American Cancer Society (Atlanta, Estats Units d'Amèrica)) ; Li, Donghui (University of Texas M.D. Anderson Cancer Center) ; Fuchs, Charles (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Hoover, Robert (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Hartge, Patricia (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Chanock, Stephen (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Petersen, Gloria M. (Mayo Clinic (Rochester, Estats Units d'Amèrica)) ; Stolzenberg-Solomon, Rachael S. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ; Wolpin, Brian M. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Department of Medical Oncology) ; Kraft, Peter (Harvard School of Public Health (Boston, Estats Units d'Amèrica)) ; Klein, Alison P. (Bloomberg School of Public Health. Department of Epidemiology) ; Canzian, Federico (German Cancer Research Center (DKFZ)) ; Amundadottir, Laufey T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica))
Genome-wide association studies (GWAS) have identified common pancreatic cancer susceptibility variants at 13 chromosomal loci in individuals of European descent. To identify new susceptibility variants, we performed imputation based on 1000 Genomes (1000G) Project data and association analysis using 5,107 case and 8,845 control subjects from 27 cohort and case-control studies that participated in the PanScan I-III GWAS. [...]
2016 - 10.18632/oncotarget.11041
Oncotarget, Vol. 7 (august 2016) , p. 66328-66343  

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2 Kraft, P.
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