Home > Search Results: Kuypers, Kim P C.
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Articles, 5 records found
Articles 5 records found  
1.
7 p, 1.1 MB Depressive mood ratings are reduced by MDMA in female polydrug ecstasy users homozygous for the l-allele of the serotonin transporter / Kuypers, Kim P. C. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; De La Torre, Rafael (Universitat Pompeu Fabra) ; Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Xicota, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ; de Sousa Fernandes Perna, Elizabeth B. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; Theunissen, E. L. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; Ramaekers, Johannes G. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
MDMA exerts its main effects via the serotonergic system and the serotonin transporter. The gene coding for this transporter determines the expression rate of the transporter. Previously it was shown that healthy individuals with the short allelic variant ('s-group') of the 5-HTTLPR-polymorphism displayed more anxiety and negative mood, and had a lower transcriptional efficiency compared to individuals who are homozygous for the l-allele ('l-group'). [...]
2018 - 10.1038/s41598-018-19618-1
Scientific reports, Vol. 8 (january 2018)  
Detailed record - Creative Commons
2.
17 p, 1.4 MB Mephedrone and Alcohol Interactions in Humans / Papaseit, Esther (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pérez-Mañá, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; de Sousa Fernandes Perna, Elizabeth B.. (Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University) ; Olesti, Eulàlia (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Mateus, Julian (Institut Hospital del Mar d'Investigacions Mèdiques) ; Kuypers, Kim P. C. (Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University) ; Theunissen, Eef L. (Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University) ; Fonseca, Francina, 1972- (Institut Hospital del Mar d'Investigacions Mèdiques) ; Torrens, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ramaekers, Jan G. (Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University) ; De La Torre, Rafael (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ; Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Mephedrone (4-MMC, mephedrone) is a synthetic cathinone derivative included in the class of new psychoactive substances. It is commonly used simultaneously with alcohol (ethanol). The aim of the present study was to evaluate the interactions on subjective, cardiovascular and hormone effects and pharmacokinetics between mephedrone and alcohol in humans. [...]
2020 - 10.3389/fphar.2019.01588
Frontiers in Pharmacology, Vol. 10 (january 2020)  
Detailed record - Creative Commons
3.
9 p, 602.7 KB MDMA-Induced Dissociative State not Mediated by the 5-HT2A Receptor / Puxty, Drew J. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; Ramaekers, Johannes G. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ; Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pizarro, Neus (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pujadas, Mitona (Institut Hospital del Mar d'Investigacions Mèdiques) ; Kuypers, Kim P. C. (Maastricht University. Department of Neuropsychology and Psychopharmacology)
Previous research has shown that a single dose of MDMA induce a dissociative state, by elevating feelings of depersonalization and derealization. Typically, it is assumed that action on the 5-HT2A receptor is the mechanism underlying these psychedelic experiences. [...]
2017 - 10.3389/fphar.2017.00455
Frontiers in Pharmacology, Vol. 8 Núm. 455 (july 2017)  
Detailed record - Creative Commons
4.
9 p, 609.8 KB Peripheral endocannabinoid concentrations are not associated with verbal memory impairment during MDMA intoxication / Haijen, E. (Maastricht, The Netherlands) ; Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pastor, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Olesti, Eulàlia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pizarro, N. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ramaekers, Johannes G (Maastricht, The Netherlands) ; Kuypers, Kim P. C (Maastricht University. Department of Neuropsychology and Psychopharmacology)
Preclinical data have suggested involvement of the endocannabinoid (eCB) system in MDMA-induced memory impairment. Clinical research has shown that blockade of the 5-HT receptor nulls memory impairment during MDMA intoxication. [...]
2017 - 10.1007/s00213-017-4787-2
Psychopharmacology, Vol. 235 (november 2017) , p. 709-717  
Detailed record - Creative Commons
5.
10 p, 560.4 KB MDMA-induced indifference to negative sounds is mediated by the 5-HT receptor / Kuypers, Kim P. C (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ; Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pizarro, N. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Xicota, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ramaekers, Johannes G (Maastricht, the Netherlands)
MDMA has been shown to induce feelings of sociability, a positive emotional bias and enhanced empathy. While previous research has used only visual emotional stimuli, communication entails more than that single dimension and it is known that auditory information is also crucial in this process. [...]
2017 - 10.1007/s00213-017-4699-1
Psychopharmacology, Vol. 235 (july 2017) , p. 481-490  
Detailed record - Creative Commons

See also: similar author names
1 Kuypers, K.P.C.
2 Kuypers, Kim P. C
3 Kuypers, Kim P. C.
3 Kuypers, Kim P. C.
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