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12 p, 2.4 MB Biomarkers and polymorphisms in pancreatic neuroendocrine tumors treated with sunitinib / Jiménez-Fonseca, Paula (Medical Oncology Department, Hospital Universitario Central de Asturias) ; Martín, Miguel Navarro (Instituto de Investigación Biomédica de Salamanca) ; Carmona-Bayonas, Alberto (Hospital General Universitario Morales Meseguer (Múrcia)) ; Calvo, Alfonso (Clínica Universidad de Navarra. Centro de Investigación Médica Aplicada) ; Fernández-Mateos, Javier (Complejo Asistencial Universitario de Salamanca. Instituto de Investigación Biomédica de Salamanca) ; Redrado, Miriam (IDISNA and Program in Solid Tumors and Biomarkers, Center for Applied Medical Research (CIMA), Department of Histology and Pathology, University of Navarra, Pamplona) ; Capdevila Castillón, Jaume (Hospital Universitari Vall d'Hebron) ; Lago, Nieves Martínez (Complejo Hospitalario Universitario de A Coruña) ; Lacasta, Adelaida (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ; Muñarriz, Javier (Consorci Hospitalari Provincial de Castelló) ; Segura, Ángel (Hospital Universitari i Politècnic La Fe (València)) ; Fuster, Josep (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Barón, Francisco (Complejo Hospitalario Universitario de Santiago de Compostela) ; Llanos, Marta (Hospital Universitario de Canarias (La Laguna)) ; Serrano, Raquel (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ; Castillo, Alfredo (Hospital Universitario Central de Asturias) ; Cruz Hernández, Juan Jesús (Instituto de Investigación Biomédica de Salamanca) ; Grande, Enrique (Medical Oncology Department, MD Anderson Cancer Center) ; Universitat Autònoma de Barcelona
Several circulating biomarkers and single nucleotide polymorphisms (SNPs) have been correlated with efficacy and tolerability to antiangiogenic agents. These associations remain unexplored in well-differentiated, metastatic pancreatic neuroendocrine tumors treated with the multitargeted tyrosine kinase inhibitor sunitinib. [...]
2018 - 10.18632/oncotarget.26380
Oncotarget, Vol. 9 (december 2018) , p. 36894-36905  
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