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1.
32 p, 22.5 MB Towards complete and error-free genome assemblies of all vertebrate species / Rhie, Arang (National Institutes of Health. National Human Genome Research Institute (USA)) ; McCarthy, Shane A. (University of Cambridge. Department of Genetics (UK)) ; Fedrigo, Olivier (The Rockefeller University. Vertebrate Genome Lab (USA)) ; Damas, Joana (University of California Davis. The Genome Center (USA)) ; Formenti, Giulio (The Rockefeller University. Vertebrate Genome Lab (USA)) ; Koren, Sergey (National Institutes of Health. National Human Genome Research Institute (USA)) ; Uliano-Silva, Marcela (Leibniz Institute for Zoo and Wildlife Research. Department of Evolutionary Genetics (Germany)) ; Chow, William (Wellcome Sanger Institute (UK)) ; Fungtammasan, Arkarachai (DNAnexus Inc. (USA)) ; Kim, Juwan (Seoul National University. Interdisciplinary Program in Bioinformatics (Republic of Korea)) ; Lee, Chul (Seoul National University. Interdisciplinary Program in Bioinformatics (Republic of Korea)) ; Ko, Byung June (Seoul National University. Department of Agricultural Biotechnology (Republic of Korea)) ; Chaisson, Mark (University of Southern California (USA)) ; Gedman, Gregory L. (The Rockefeller University. Laboratory of Neurogenetics of Language (USA)) ; Cantin, Lindsey J. (The Rockefeller University. Laboratory of Neurogenetics of Language (USA)) ; Thibaud-Nissen, Francoise (National Library of Medicine. National Center for Biotechnology Information (USA)) ; Haggerty, Leanne (European Bioinformatics Institute. European Molecular Biology Laboratory (UK)) ; Bista, Iliana (University of Cambridge. Department of Genetics (UK)) ; Smith, Michelle (Wellcome Sanger Institute (UK)) ; Haase, Bettina (The Rockefeller University. Vertebrate Genome Lab (USA)) ; Mountcastle, Jacquelyn (The Rockefeller University. Vertebrate Genome Lab (USA)) ; Winkler, Sylke (Max Planck Institute of Molecular Cell Biology and Genetics (Germany)) ; Paez, Sadye (The Rockefeller University. Vertebrate Genome Lab (USA)) ; Howard, Jason (Novogene (USA)) ; Vernes, Sonja C. (Donders Institute for Brain, Cognition and Behaviour (The Netherlands)) ; Lama, Tanya M. (University of Massachusetts. Cooperative Fish and Wildlife Research Unit (USA)) ; Marques-Bonet, Tomas (Institut Català de Paleontologia Miquel Crusafont) ; Warren, Wesley C. (University of Missouri. Bond Life Sciences Center (USA)) ; Balakrishnan, Christopher N. (East Carolina University. Department of Biology (USA)) ; Burt, Dave (University of Queensland. UQ Genomics (Australia)) ; George, Julia M. ; Biegler, Matthew T. (The Rockefeller University. Laboratory of Neurogenetics of Language (USA)) ; Iorns, David (The Genetic Rescue Foundation (New Zealand)) ; Digby, Andrew (Kākāpō Recovery, Department of Conservation (New Zealand)) ; Eason, Daryl (Kākāpō Recovery, Department of Conservation (New Zealand)) ; Robertson, Bruce (University of Otago. Department of Zoology (New Zealand)) ; Edwards, Taylor (University of Arizona Genetics Core (USA)) ; Wilkinson, Mark (Natural History Museum. Department of Life Sciences (UK)) ; Turner, George (Bangor University. School of Natural Sciences (UK)) ; Meyer, Axel (University of Konstanz. Department of Biology (Germany)) ; Kautt, Andreas F. (University of Konstanz. Department of Biology (Germany)) ; Franchini, Paolo (University of Konstanz. Department of Biology (Germany)) ; Detrich III, H. William (Northeastern University Marine Science Center. Department of Marine and Environmental Sciences (USA)) ; Svardal, Hannes (University of Antwerp. Department of Biology (Belgium)) ; Wagner, Maximilian (Karl-Franzens University of Graz. Institute of Biology (Austria)) ; Naylor, Gavin J. P. (University of Florida. Florida Museum of Natural History (USA)) ; Pippel, Martin (Max Planck Institute of Molecular Cell Biology and Genetics (Germany)) ; Malinsky, Milan (University of Basel. Zoological Institute (Switzerland)) ; Mooney, Mark (Tag.bio (USA)) ; Simbirsky, Maria (DNAnexus Inc. (USA)) ; Hannigan, Brett T. (DNAnexus Inc. (USA)) ; Pesout, Trevor (University of California. UC Santa Cruz Genomics Institute (USA)) ; Houck, Marlys (San Diego Zoo Global (USA)) ; Misuraca, Ann (San Diego Zoo Global (USA)) ; Kingan, Sarah B. (Pacific Biosciences (USA)) ; Hall, Richard (Pacific Biosciences (USA)) ; Kronenberg, Zev (Pacific Biosciences (USA)) ; Sović, Ivan (Pacific Biosciences (USA)) ; Dunn, Christopher (Pacific Biosciences (USA)) ; Ning, Zemin (Wellcome Sanger Institute (UK)) ; Hastie, Alex (Bionano Genomics (USA)) ; Lee, Joyce (Bionano Genomics (USA)) ; Selvaraj, Siddarth (Arima Genomics (USA)) ; Green, Richard E. (University of California. UC Santa Cruz Genomics Institute (USA)) ; Putnam, Nicholas H. (Independent Researcher. Santa Cruz (USA)) ; Gut, Ivo (Centro Nacional de Análisis Genómico. Instituto de Ciencia y Tecnología de Barcelona) ; Ghurye, Jay (University of Maryland College Park. Department of Computer Science (USA)) ; Garrison, Erik (University of California. UC Santa Cruz Genomics Institute (USA)) ; Sims, Ying (Wellcome Sanger Institute (UK)) ; Collins, Joanna (Wellcome Sanger Institute (UK)) ; Pelan, Sarah (Wellcome Sanger Institute (UK)) ; Torrance, James (Wellcome Sanger Institute (UK)) ; Tracey, Alan (Wellcome Sanger Institute (UK)) ; Wood, Jonathan (Wellcome Sanger Institute (UK)) ; Dagnew, Robel E. (University of Southern California (USA)) ; Guan, Dengfeng (Harbin Institute of Technology. Center for Bioinformatics. School of Computer Science and Technology (China)) ; London, Sarah E. (University of Chicago. Institute for Mind and Biology. Department of Psychology (USA)) ; Clayton, David F. (Clemson University. Department of Genetics and Biochemistry (USA)) ; Mello, Claudio V. (Oregon Health and Science University. Department of Behavioral Neuroscience (USA)) ; Friedrich, Samantha R. (Oregon Health and Science University. Department of Behavioral Neuroscience (USA)) ; Lovell, Peter V. (Oregon Health and Science University. Department of Behavioral Neuroscience (USA)) ; Osipova, Ekaterina (Max Planck Institute for the Physics of Complex Systems (Germany)) ; Al-Ajli, Farooq O. (Monash University Malaysia. Tropical Medicine and Biology Multidisciplinary Platform (Malaysia)) ; Secomandi, Simona (University of Milan. Department of Biosciences (Italy)) ; Kim, Heebal (Seoul National University. Interdisciplinary Program in Bioinformatics (Republic of Korea)) ; Theofanopoulou, Constantina (The Rockefeller University. Laboratory of Neurogenetics of Language (USA)) ; Hiller, Michael (Goethe-University. Faculty of Biosciences (Germany)) ; Zhou, Yang (BGI-Shenzhen (China)) ; Harris, Robert S. (Pennsylvania State University. Department of Biology (USA)) ; Makova, Kateryna D. (Pennsylvania State University. Department of Biology (USA)) ; Medvedev, Paul (Pennsylvania State University. Center for Medical Genomics (USA)) ; Hoffman, Jinna (National Library of Medicine. National Center for Biotechnology Information (USA)) ; Masterson, Patrick (National Library of Medicine. National Center for Biotechnology Information (USA)) ; Clark, Karen (National Library of Medicine. National Center for Biotechnology Information (USA)) ; Martin, Fergal (European Bioinformatics Institute. European Molecular Biology Laboratory (UK)) ; Howe, Kevin (European Bioinformatics Institute. European Molecular Biology Laboratory (UK)) ; Flicek, Paul (European Bioinformatics Institute. European Molecular Biology Laboratory (UK)) ; Walenz, Brian P. (National Institutes of Health. National Human Genome Research Institute (USA)) ; Kwak, Woori (eGnome, Inc. (Republic of Korea)) ; Clawson, Hiram (University of California. UC Santa Cruz Genomics Institute (USA)) ; Diekhans, Mark (University of California. UC Santa Cruz Genomics Institute (USA)) ; Nassar, Luis (University of California. UC Santa Cruz Genomics Institute (USA)) ; Paten, Benedict (University of California. UC Santa Cruz Genomics Institute (USA)) ; Kraus, Robert H. S. (Max Planck Institute of Animal Behavior. Department of Migration (Germany)) ; Crawford, Andrew J. (Universidad de los Andes. Department of Biological Sciences (Colombia)) ; Gilbert, M. Thomas P. (University of Copenhagen. The GLOBE Institute. Center for Evolutionary Hologenomics (Denmark)) ; Zhang, Guojie (Chinese Academy of Sciences. Center for Excellence in Animal Evolution and Genetics (China)) ; Venkatesh, Byrappa (A*STAR. Institute of Molecular and Cell Biology (Singapore)) ; Murphy, Robert W. (Royal Ontario Museum. Centre for Biodiversity (Canada)) ; Koepfli, Klaus-Peter (National Zoological Park. Smithsonian Conservation Biology Institute. Center for Species Survival (USA)) ; Shapiro, Beth (Howard Hughes Medical Institute (USA)) ; Johnson, Warren E. (National Zoological Park. Smithsonian Conservation Biology Institute. Center for Species Survival (USA)) ; Di Palma, Federica (University of East Anglia. Earlham Institute. Department of Biological Sciences (UK)) ; Teeling, Emma C. (University College Dublin. School of Biology and Environmental Science (Ireland)) ; Warnow, Tandy (The University of Illinois at Urbana-Champaign. Department of Computer Science (USA)) ; Graves, Jennifer Marshall (La Trobe University. School of Life Science (Australia)) ; Ryder, Oliver A. (University of California San Diego. Department of Evolution, Behavior, and Ecology (USA)) ; Haussler, David (University of California Santa Cruz. Department of Ecology and Evolutionary Biology (USA)) ; O'Brien, Stephen J. (ITMO University. Laboratory of Genomics Diversity-Center for Computer Technologies (Russian Federation)) ; Korlach, Jonas (Pacific Biosciences (USA)) ; Lewin, Harris A. (University of California Davis. John Muir Institute for the Environment (USA)) ; Howe, Kerstin (Wellcome Sanger Institute (UK)) ; Myers, Eugene W. (Max Planck Institute of Molecular Cell Biology and Genetics (Germany)) ; Durbin, Richard (University of Cambridge. Department of Genetics (UK)) ; Phillippy, Adam M. (National Institutes of Health. National Human Genome Research Institute (USA)) ; Jarvis, Erich D. (The Rockefeller University. Vertebrate Genome Lab (USA))
High-quality and complete reference genome assemblies are fundamental for the application of genomics to biology, disease, and biodiversity conservation. However, such assemblies are available for only a few non-microbial species 1, 2, 3, 4. [...]
2021 - 10.1038/s41586-021-03451-0
Nature, Vol. 592 (April 2021) , p. 737-746  
2.
10 p, 736.9 KB Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage : a systematic review and meta-analysis of individual patient data / Al-Shahi Salman, Rustam (Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK) ; Frantzias, Joseph (Department of Neurosurgery, King's College Hospital, London, UK) ; Lee, Robert J (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK) ; Lyden, Patrick D (Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA) ; Battey, Thomas W K (Department of Neurology, Massachusetts General Hospital, Boston, MA, USA) ; Ayres, Alison M (Department of Neurology, Massachusetts General Hospital, Boston, MA, USA) ; Goldstein, Joshua N (Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA) ; Mayer, Stephan A (Department of Neurology, Henry Ford Health System, Detroit, MI, USA) ; Steiner, Thorsten (Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany) ; Wang, Xia (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ; Arima, Hisatomi (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ; Hasegawa, Hitoshi (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Oishi, Makoto (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Godoy, Daniel A (Intensive Care Unit, Hospital Interzonal de Agudos "San Juan Bautista", Catamarca, Argentina) ; Masotti, Luca (Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy) ; Dowlatshahi, Dar (Department of Medicine (Neurology), University of Ottawa and Ottawa Hospital Research Institute, Ottawa, ON, Canada) ; Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Molina, Carlos A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jang, Dong-Kyu (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ; Davalos, Antonio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Castillo, José (Department of Neurology, University Clinical Hospital of Santiago, Santiago de Compostela, Spain) ; Yao, Xiaoying (Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China) ; Claassen, Jan (Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ; Volbers, Bastian (Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland) ; Kazui, Seiji (Kazui Medical Office, Ikeda, Osaka, Japan) ; Okada, Yasushi (Department of Cerebrovascular Medicine and Neurology, National Hospital Organisation Kyushu Medical Centre, Fukuoka, Japan) ; Fujimoto, Shigeru (Division of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan) ; Toyoda, Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Li, Qi (Department of Neurology, ThE First Affiliated Hospital of Chongqing Medical University, Chongqing, China) ; Khoury, Jane (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ; Delgado, Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sabín, José Álvarez (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernández-Guillamon, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Prats-Sánchez, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Cai, Chunyan (Centre for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA) ; Kate, Mahesh P (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; McCourt, Rebecca (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; Venkatasubramanian, Chitra (Division of Stroke and Neurocritical Care, Stanford University, Palo Alto, CA, USA) ; Diringer, Michael N (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ; Ikeda, Yukio (Department of Neurosurgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan) ; Worthmann, Hans (Department of Neurology, Hannover Medical School, Hannover, Germany) ; Ziai, Wendy C (Johns Hopkins University School of Medicine, Department of Neurology, Anaesthesia and Critical Care Medicine, Division of Neurocritical Care, Baltimore, MD, USA) ; d'Esterre, Christopher D (Department of Radiology, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada) ; Aviv, Richard I (Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada) ; Raab, Peter (Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany) ; Murai, Yasuo (Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan) ; Zazulia, Allyson R (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ; Butcher, Kenneth S (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; Seyedsaadat, Seyed Mohammad (Department of Radiology, Mayo Clinic, Rochester, MN, USA) ; Grotta, James C (Memorial Hermann Hospital, Clinical Innovation and Research Institute, Houston, TX, USA) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Broderick, Joseph (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ; Yamamoto, Haruko (Center for Advanced Clinical and Translational Sciences, National Cerebral and Cerebrovascular Center, Suita, Osaka, Japan) ; Staykov, Dimitre (Department of Neurology, Hospital of the Brothers of St John, Eisenstadt, Austria) ; Connolly, E Sander (Department of Neurosurgery, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ; Selim, Magdy (Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ; Leira, Rogelio (Department of Neurology, University Clinical Hospital of Santiago, Santiago de Compostela, Spain) ; Moon, Byung Hoo (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ; Demchuk, Andrew M (Department of Clinical Neurosciences and Department of Radiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada) ; Di Napoli, Mario (Neurological Service, San Camillo de'Lellis General Hospital, Rieti, Italy) ; Fujii, Yukihiko (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Anderson, Craig S (The George Institute for Global Health, China at Peking University Health Science Center, Beijing, China) ; Rosand, Jonathan (Department of Neurology, Massachusetts General Hospital, Boston, MA, USA) ; Universitat Autònoma de Barcelona
Intracerebral haemorrhage growth is associated with poor clinical outcome and is a therapeutic target for improving outcome. We aimed to determine the absolute risk and predictors of intracerebral haemorrhage growth, develop and validate prediction models, and evaluate the added value of CT angiography. [...]
2018 - 10.1016/S1474-4422(18)30253-9
The Lancet neurology, Vol. 17 (october 2018) , p. 885-894  
3.
14 p, 236.7 KB Clinical Variables and Genetic Risk Factors Associated with the Acute Outcome of Ischemic Stroke : A Systematic Review / Torres-Aguila, Nuria P (Institut d'Investigació Biomèdica Sant Pau) ; Carrera, Caty (Institut d'Investigació Biomèdica Sant Pau) ; Muiño, Elena (Institut d'Investigació Biomèdica Sant Pau) ; Cullell, Natalia (Stroke Pharmacogenomics and Genetics Laboratory, Mutua Terrasa Foundation of Teaching and Research, Mutua Terrassa Hospital, Terrassa) ; Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ; Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; González-Sánchez, Jonathan (Institut d'Investigació Biomèdica Sant Pau) ; Bustamante, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Delgado, Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ibañez, Laura (Department of Psychiatry, Washington University School of Medicine, St. Louis, MO) ; Heitsch, Laura (Department of Neurology, Washington University School of Medicine, St. Louis, MO) ; Krupinski, Jerzy (Health Care Science Department, The Manchester Metropolitan University of All Saints, Manchester) ; Montaner, Joan (Department of Neurology, Virgin Rocío and Macarena Hospitals, Institute of Biomedicine of Seville (IBiS), Seville) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Cruchaga, Carlos (Department of Psychiatry, Washington University School of Medicine, St. Louis, MO) ; Lee, Jin-Moo (Department of Neurology, Washington University School of Medicine, St. Louis, MO) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Stroke is a complex disease and one of the main causes of morbidity and mortality among the adult population. A huge variety of factors is known to influence patient outcome, including demographic variables, comorbidities or genetics. [...]
2019 - 10.5853/jos.2019.01522
Journal of Stroke, Vol. 21 (september 2019) , p. 276-289  
4.
14 p, 1.2 MB A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity / van der Lee, Sven J. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ; Conway, Olivia J. (Mayo Clinic Florida. Department of Neuroscience) ; Jansen, Iris (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ; Carrasquillo, Minerva M. (Mayo Clinic Florida. Department of Neuroscience) ; Kleineidam, Luca (University Hospital Cologne. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine) ; van den Akker, Erik (Delft University of Technology. Pattern Recognition and Bioinformatics) ; Hernández, Isabel (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; van Eijk, Kristel R. (University Medical Center Utrecht. Department of Neurology, Brain Center Rudolf Magnus) ; Stringa, Najada (Amsterdam Public Health Research Institute. Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Biostatistics) ; Chen, Jason A. (University of California. Interdepartmental Program in Bioinformatics) ; Zettergren, Anna (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ; Andlauer, Till F. M. (German Competence Network Multiple Sclerosis (KKNMS)) ; Diez-Fairen, Monica (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ; Simon-Sanchez, Javier (University of Tübingen. Hertie Institute for Clinical Brain Research) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Zetterberg, Henrik (UCL Institute of Neurology, Queen Square. Department of Molecular Neuroscience) ; Nygaard, Marianne (University of Southern Denmark. The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health) ; Blauwendraat, Cornelis (National Institute of Neurological Disorders and Stroke. Neurodegenerative Diseases Research Unit) ; Savage, Jeanne E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ; Mengel-From, Jonas (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ; Moreno-Grau, Sonia (Institut Català de Neurociènces Aplicades) ; Wagner, Michael (DZNE, German Center for Neurodegenerative Diseases) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Keogh, Michael J. (University of Cambridge. Department of Clinical Neurosciences) ; Blennow, Kaj (Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg. Department of Psychiatry and Neurochemistry) ; Skoog, Ingmar (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ; Friese, Manuel A. (Universitätsklinikum Hamburg-Eppendorf. Institut für Neuroimmunologie und Multiple Sklerose (INIMS)) ; Pletnikova, Olga (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ; Zulaica, Miren (Instituto Biodonostia) ; Lage, Carmen (IDIVAL) ; de Rojas, Itziar (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Riedel-Heller, Steffi (University of Leipzig. Institute of Social Medicine, Occupational Health and Public Health (ISAP)) ; Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ; Wei, Wei (University of Cambridge. Department of Clinical Neurosciences) ; Jeune, Bernard (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ; Orellana, Adelina (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Then Bergh, Florian (University of Leipzig. Department of Neurology) ; Wang, Xue (Mayo Clinic Florida. Department of Neuroscience) ; Hulsman, Marc (Delft University of Technology. Pattern Recognition and Bioinformatics) ; Beker, Nina (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Tesi, Niccolo (Delft University of Technology. Pattern Recognition and Bioinformatics) ; Morris, Christopher M. (Newcastle University. Newcastle Brain Tissue Resource, Edwardson Building, Institute of Neuroscience) ; Indakoetxea, Begoña (Cognitive Disorders Unit, Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ; Collij, Lyduine E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ; Scherer, Martin (Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center, Hamburg-Eppendorf, Germany) ; Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ; Ironside, James W. (University of Edinburgh. Centre for Clinical Brain Sciences) ; van Berckel, Bart N. M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Wiendl, Heinz (University of Münster. Department of Neurology, Klinik für Neurologie mit Institut für Translationale Neurologie) ; Strickland, Samantha L. (Mayo Clinic Florida. Department of Neuroscience) ; Pastor, Pau (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ; Rodríguez Rodríguez, Eloy (IDIVAL) ; Boeve, Bradley F. (Mayo Clinic Minnesota. Department of Neurology) ; Petersen, Ronald C. (Mayo Clinic Minnesota. Department of Neurology) ; Ferman, Tanis J. (Mayo Clinic Florida. Department of Psychiatry and Psychology) ; van Gerpen, Jay A. (Mayo Clinic Florida. Department of Neurology) ; Reinders, Marcel J. T. (Delft University of Technology. Delft Bioinformatics Lab) ; Uitti, Ryan J. (Mayo Clinic Florida. Department of Neurology) ; Tárraga, Lluís (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Maier, Wolfgang (DZNE, German Center for Neurodegenerative Diseases) ; Dols-Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Kawalia, Amit (University Hospital Cologne. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine) ; Dalmasso, Maria Carolina (Fundación Instituto Leloir-IIBBA-CONICET) ; Boada, Mercè (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Zettl, Uwe K. (University of Rostock. Department of Neurology) ; van Schoor, Natasja M. (Amsterdam Public Health Research Institute. Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Biostatistics) ; Beekman, Marian (Leiden University Medical Center. Molecular Epidemiology) ; Allen, Mariet (Mayo Clinic Florida. Department of Neuroscience) ; Masliah, Eliezer (National Institute on Aging, National Institutes of Health. Laboratory of Neurogenetics) ; de Munain, Adolfo López (Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ; Pantelyat, Alexander (Johns Hopkins University Medical Center. Department of Neurology) ; Wszolek, Zbigniew K. (Mayo Clinic Florida. Department of Neurology) ; Ross, Owen A. (Mayo Clinic Florida. Department of Neuroscience) ; Dickson, Dennis W. (Mayo Clinic Florida. Department of Neuroscience) ; Graff-Radford, Neill R. (Mayo Clinic Florida. Department of Neurology) ; Knopman, David (Mayo Clinic Minnesota. Department of Neurology) ; Rademakers, Rosa (Mayo Clinic Florida. Department of Neuroscience) ; Lemstra, Afina W. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Pijnenburg, Yolande A. L. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Scheltens, Philip (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Gasser, Thomas (University of Tuebingen. Center of Neurology, Department of Neurodegenerative diseases, Hertie-Institute for Clinical Brain Research) ; Chinnery, Patrick F (University of Cambridge. MRC Mitochondrial Biology Unit) ; Hemmer, Bernhard (Munich Cluster for Systems Neurology (SyNergy)) ; Huisman, Martijn A. (VU University. Department of Sociology) ; Troncoso, Juan (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ; Moreno, Fermin (Cognitive Disorders Unit, Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ; Nohr, Ellen A. (University of Southern Denmark. Research Unit of Gynecology and Obstetrics, Department of Clinical Research) ; Sørensen, Thorkild I. A. (Bristol University. MRC Integrative Epidemiology Unit) ; Heutink, Peter (University of Tübingen. Hertie Institute for Clinical Brain Research) ; Sánchez-Juan, Pascual (IDIVAL) ; Posthuma, Danielle (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ; Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Christensen, Kaare (Odense University Hospital. Department of Clinical Genetics) ; Ertekin-Taner, Nilüfer (Mayo Clinic Florida. Department of Neurology) ; Scholz, Sonja W. (Johns Hopkins University Medical Center. Department of Neurology) ; Ramirez, Alfredo (University Hospital Cologne. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine) ; Ruiz, Agustín (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Slagboom, Eline (Dutch Society for Research on Ageing, Leiden, The Netherlands) ; van der Flier, Wiesje M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Holstege, Henne (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ; Universitat Autònoma de Barcelona
The online version of this article (10. 1007/s00401-019-02026-8) contains supplementary material, which is available to authorized users.
2019 - 10.1007/s00401-019-02026-8
Acta Neuropathologica, Vol. 138 (may 2019) , p. 237-250  
5.
13 p, 818.2 KB Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack : a pooled analysis of individual patient data from cohort studies / Wilson, Duncan (New Zealand Brain Research Institute, Christchurch, New Zealand) ; Ambler, Gareth (Department of Statistical Science, University College London, London, UK) ; Lee, Keon-Joo (Department of Neurology, Seoul National University Bundang Hospital, Seoul National University School of Medicine, Seongnam, South Korea) ; Lim, Jae-Sung (Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, South Korea) ; Shiozawa, Masayuki (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Koga, Masatoshi (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Li, Linxin (Centre for Prevention of Stroke and Dementia, University of Oxford, Oxford, UK) ; Lovelock, Caroline (Centre for Prevention of Stroke and Dementia, University of Oxford, Oxford, UK) ; Chabriat, Hugues (Département Hospitalo-Universtaire NeuroVasc, University Paris Diderot, and INSERM U1141, Paris, France) ; Hennerici, Michael (Department of Neurology, Universitätsmedizin Mannheim, University of Heidelberg, Mannheim, Germany) ; Wong, Yuen Kwun (Division of Neurology, Department of Medicine, The University of Hong Kong, Hong Kong) ; Mak, Henry Ka Fung (Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong) ; Prats-Sánchez, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Martínez-Domeño, Alejandro (Institut d'Investigació Biomèdica Sant Pau) ; Inamura, Shigeru (Department of Neurosurgery, Kushiro City General Hospital, Kushiro, Japan) ; Yoshifuji, Kazuhisa (Department of Neurosurgery, Kushiro City General Hospital, Kushiro, Japan) ; Arsava, Ethem Murat (Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston MA, USA) ; Horstmann, Solveig (Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany) ; Purrucker, Jan (Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany) ; Lam, Bonnie Yin Ka (Therese Pei Fong Chow Research Centre for Prevention of Dementia, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong) ; Wong, Adrian (Therese Pei Fong Chow Research Centre for Prevention of Dementia, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong) ; Kim, Young Dae (Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea) ; Song, Tae-Jin (Department of Neurology, Ewha Womans University College of Medicine, Seoul, South Korea) ; Schrooten, Maarten (Center for Brain and Disease Research, VIB, Leuven, Belgium) ; Lemmens, Robin (Experimental Neurology and Leuven Institute for Neuroscience and Disease, Katholieke Universiteit Leuven, University of Leuven, Laboratory of Neurobiology, Leuven, Belgium) ; Eppinger, Sebastian (Department of Neurology, Medical University of Graz, Graz, Austria) ; Gattringer, Thomas (Department of Neurology, Medical University of Graz, Graz, Austria) ; Uysal, Ender (Department of Neurology, Demiroglu Bilim University, Istanbul, Turkey) ; Tanriverdi, Zeynep (Department of Neurology, Demiroglu Bilim University, Istanbul, Turkey) ; Bornstein, Natan M (Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel) ; Assayag, Einor Ben (Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel) ; Hallevi, Hen (Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel) ; Tanaka, Jun (Division of Neurology, Department of Internal Medicine, Saga University Faculty of Medicine, Nabeshima, Saga, Japan) ; Hara, Hideo (Division of Neurology, Department of Internal Medicine, Saga University Faculty of Medicine, Nabeshima, Saga, Japan) ; Coutts, Shelagh B (Calgary Stroke Program, Department of Clinical Neurosciences, Radiology and Community Health Sciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada) ; Hert, Lisa (Department of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland) ; Polymeris, Alexandros (Department of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland) ; Seiffge, David J (Department of Diagnostic and Interventional Neuroradiology and Department of Neurology Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland) ; Lyrer, Philippe (Department of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland) ; Algra, Ale (Department of Neurology and Neurosurgery, Utrecht Stroke Centre, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands) ; Kappelle, Jaap (Department of Neurology and Neurosurgery, Utrecht Stroke Centre, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands) ; Al-Shahi Salman, Rustam (Centre for Clinical Brain Sciences, School of Clinical Sciences, University of Edinburgh, Edinburgh, UK) ; Jäger, Hans R (Lysholm Department of Neuroradiology and the Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, UK) ; Lip, Gregory Y H (Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark) ; Mattle, Heinrich P (Department of Diagnostic and Interventional Neuroradiology and Department of Neurology Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland) ; Panos, Leonidas D (Department of Diagnostic and Interventional Neuroradiology and Department of Neurology Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland) ; Mas, Jean-Louis (Department of Neurology, Sainte-Anne Hospital, Paris Descartes University, INSERM U1266, Paris, France) ; Legrand, Laurence (Department of Neuroradiology, Sainte-Anne Hospital, Paris Descartes University, INSERM U1266, Paris, France) ; Karayiannis, Christopher (Peninsula Clinical School, Peninsula Health, Monash University, Melbourne, VIC, Australia) ; Phan, Thanh (Stroke and Ageing Research Group, School of Clinical Sciences at Monash Health, Monash University, Melbourne, VIC, Australia) ; Gunkel, Sarah (Department of Neurology, University Hospital of Würzburg, Josef-Schneider Strasse 11, Würzburg, Germany) ; Christ, Nicolas (Department of Neurology, University Hospital of Würzburg, Josef-Schneider Strasse 11, Würzburg, Germany) ; Abrigo, Jill (Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Leung, Thomas (Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Chu, Winnie (Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Chappell, Francesca (UK Dementia Institute at the University of Edinburgh, School of Clinical Sciences, University of Edinburgh, Edinburgh, UK) ; Makin, Stephen (Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, UK) ; Hayden, Derek (The Neurovascular Research Unit and Health Research Board, Stroke Clinical Trials Network Ireland, University College Dublin, Dublin, Ireland) ; Williams, David J (Beaumont Hospital Dublin, Ireland) ; Kooi, M Eline (Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, Netherlands) ; van Dam-Nolen, Dianne H K (Department of Radiology and Nuclear Medicine, Erasmus Medical Centre, University Medical Centre, Rotterdam, Netherlands) ; Barbato, Carmen (Comprehensive Stroke Service, University College London Hospitals NHS Trust, London, UK) ; Browning, Simone (Comprehensive Stroke Service, University College London Hospitals NHS Trust, London, UK) ; Wiegertjes, Kim (Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Donders Centre for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands) ; Tuladhar, Anil M (Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Donders Centre for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands) ; Maaijwee, Noortje (Lucerne State Hospital; Switzerland Center for Neurology and Neurorehabilitation, Luzern, Switzerland) ; Guevarra, Christine (Department of Neurology, National Neuroscience Institute, Singapore, Singapore) ; Yatawara, Chathuri (Department of Neurology, National Neuroscience Institute, Singapore, Singapore) ; Mendyk, Anne-Marie (University of Lille, Inserm, CHU de Lille, Degenerative and vascular cognitive disorders U1171, Lille, France) ; Delmaire, Christine (University of Lille, Inserm, CHU de Lille, Degenerative and vascular cognitive disorders U1171, Lille, France) ; Köhler, Sebastian (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands) ; van Oostenbrugge, Robert (Department of Neurology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht, Netherlands) ; Zhou, Ying (Department of Neurology, The 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China) ; Xu, Chao (Department of Neurology, The 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China) ; Hilal, Saima (Memory Aging and Cognition Centre, National University Health System, Singapore, Singapore) ; Gyanwali, Bibek (Memory Aging and Cognition Centre, National University Health System, Singapore, Singapore) ; Chen, Christopher (Memory Aging and Cognition Centre, National University Health System, Singapore, Singapore) ; Lou, Min (Department of Neurology, The 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China) ; Staals, Julie (Department of Neurology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht, Netherlands) ; Bordet, Régis (University of Lille, Inserm, CHU de Lille, Degenerative and vascular cognitive disorders U1171, Lille, France) ; Kandiah, Nagaendran (Department of Neurology, National Neuroscience Institute, Singapore, Singapore) ; de Leeuw, Frank-Erik (Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Donders Centre for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands) ; Simister, Robert (Comprehensive Stroke Service, University College London Hospitals NHS Trust, London, UK) ; van der Lugt, Aad (Department of Radiology and Nuclear Medicine, Erasmus Medical Centre, University Medical Centre, Rotterdam, Netherlands) ; Kelly, Peter J (The Neurovascular Research Unit and Health Research Board, Stroke Clinical Trials Network Ireland, University College Dublin, Dublin, Ireland) ; Wardlaw, Joanna M (UK Dementia Institute at the University of Edinburgh, School of Clinical Sciences, University of Edinburgh, Edinburgh, UK) ; Soo, Yannie (Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Fluri, Felix (Department of Neurology, University Hospital of Würzburg, Josef-Schneider Strasse 11, Würzburg, Germany) ; Srikanth, Velandai (Peninsula Clinical School, Peninsula Health, Monash University, Melbourne, VIC, Australia) ; Calvet, David (Department of Neurology, Sainte-Anne Hospital, Paris Descartes University, INSERM U1266, Paris, France) ; Jung, Simon (Department of Diagnostic and Interventional Neuroradiology and Department of Neurology Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland) ; Kwa, Vincent I H (Department of Neurology, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands) ; Engelter, Stefan T (Neurology and Neurorehabilitation, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, Switzerland) ; Peters, Nils (Neurology and Neurorehabilitation, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, Switzerland) ; Smith, Eric E (Calgary Stroke Program, Department of Clinical Neurosciences, Radiology and Community Health Sciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada) ; Yakushiji, Yusuke (Division of Neurology, Department of Internal Medicine, Saga University Faculty of Medicine, Nabeshima, Saga, Japan) ; Orken, Dilek Necioglu (Department of Neurology, Demiroglu Bilim University, Istanbul, Turkey) ; Fazekas, Franz (Department of Neurology, Medical University of Graz, Graz, Austria) ; Thijs, Vincent (Department of Neurosciences, University Hospitals Leuven, Belgium) ; Heo, Ji Hoe (Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea) ; Mok, Vincent (Therese Pei Fong Chow Research Centre for Prevention of Dementia, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong) ; Veltkamp, Roland (Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany) ; Ay, Hakan (Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Boston MA, USA) ; Imaizumi, Toshio (Department of Neurosurgery, Kushiro City General Hospital, Kushiro, Japan) ; Gómez Ansón, Beatriz (Institut d'Investigació Biomèdica Sant Pau) ; Lau, Kui Kai (Division of Neurology, Department of Medicine, The University of Hong Kong, Hong Kong) ; Jouvent, Eric (Département Hospitalo-Universtaire NeuroVasc, University Paris Diderot, and INSERM U1141, Paris, France) ; Rothwell, Peter M (Centre for Prevention of Stroke and Dementia, University of Oxford, Oxford, UK) ; Toyoda, Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Bae, Hee-Joon (Department of Neurology, Seoul National University Bundang Hospital, Seoul National University School of Medicine, Seongnam, South Korea) ; Marti-Fabregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Werring, David J (Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, London, UK) ; Universitat Autònoma de Barcelona
Cerebral microbleeds are a neuroimaging biomarker of stroke risk. A crucial clinical question is whether cerebral microbleeds indicate patients with recent ischaemic stroke or transient ischaemic attack in whom the rate of future intracranial haemorrhage is likely to exceed that of recurrent ischaemic stroke when treated with antithrombotic drugs. [...]
2019 - 10.1016/S1474-4422(19)30197-8
The Lancet neurology, Vol. 18 (july 2019) , p. 653-665  
6.
4 p, 417.7 KB Correction to : A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity / van der Lee, Sven J. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ; Conway, Olivia J. (Mayo Clinic Florida. Department of Neuroscience) ; Jansen, Iris (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ; Carrasquillo, Minerva M. (Mayo Clinic Florida. Department of Neuroscience) ; Kleineidam, Luca (University Hospital Cologne. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine) ; van den Akker, Erik (Delft University of Technology. Pattern Recognition and Bioinformatics) ; Hernández, Isabel (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; van Eijk, Kristel R. (University Medical Center Utrecht. Department of Neurology, Brain Center Rudolf Magnus) ; Stringa, Najada (Amsterdam Public Health Research Institute. Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Biostatistics) ; Chen, Jason A. (University of California. Interdepartmental Program in Bioinformatics) ; Zettergren, Anna (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ; Andlauer, Till F. M. (German Competence Network Multiple Sclerosis (KKNMS)) ; Diez-Fairen, Monica (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ; Simon-Sanchez, Javier (University of Tübingen. Hertie Institute for Clinical Brain Research) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Zetterberg, Henrik (UCL Institute of Neurology, Queen Square. Department of Molecular Neuroscience) ; Nygaard, Marianne (University of Southern Denmark. The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health) ; Blauwendraat, Cornelis (National Institute of Neurological Disorders and Stroke. Neurodegenerative Diseases Research Unit) ; Savage, Jeanne E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ; Mengel-From, Jonas (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ; Moreno-Grau, Sonia (Institut Català de Neurociènces Aplicades) ; Wagner, Michael (DZNE, German Center for Neurodegenerative Diseases) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Keogh, Michael J. (University of Cambridge. Department of Clinical Neurosciences) ; Blennow, Kaj (Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg. Department of Psychiatry and Neurochemistry) ; Skoog, Ingmar (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ; Friese, Manuel A. (Universitätsklinikum Hamburg-Eppendorf. Institut für Neuroimmunologie und Multiple Sklerose (INIMS)) ; Pletnikova, Olga (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ; Zulaica, Miren (Instituto Biodonostia) ; Lage, Carmen (IDIVAL) ; de Rojas, Itziar (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Riedel-Heller, Steffi (University of Leipzig. Institute of Social Medicine, Occupational Health and Public Health (ISAP)) ; Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ; Wei, Wei (University of Cambridge. Department of Clinical Neurosciences) ; Jeune, Bernard (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ; Orellana, Adelina (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Then Bergh, Florian (University of Leipzig. Department of Neurology) ; Wang, Xue (Mayo Clinic Florida. Department of Neuroscience) ; Hulsman, Marc (Delft University of Technology. Pattern Recognition and Bioinformatics) ; Beker, Nina (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Tesi, Niccolo (Delft University of Technology. Pattern Recognition and Bioinformatics) ; Morris, Christopher M. (Newcastle University. Newcastle Brain Tissue Resource, Edwardson Building, Institute of Neuroscience) ; Indakoetxea, Begoña (Cognitive Disorders Unit, Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ; Collij, Lyduine E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ; Scherer, Martin (Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center, Hamburg-Eppendorf, Germany) ; Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ; Ironside, James W. (University of Edinburgh. Centre for Clinical Brain Sciences) ; van Berckel, Bart N. M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Wiendl, Heinz (University of Münster. Department of Neurology, Klinik für Neurologie mit Institut für Translationale Neurologie) ; Strickland, Samantha L. (Mayo Clinic Florida. Department of Neuroscience) ; Pastor, Pau (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ; Rodríguez Rodríguez, Eloy (IDIVAL) ; Boeve, Bradley F. (Mayo Clinic Minnesota. Department of Neurology) ; Petersen, Ronald C. (Mayo Clinic Minnesota. Department of Neurology) ; Ferman, Tanis J. (Mayo Clinic Florida. Department of Psychiatry and Psychology) ; van Gerpen, Jay A. (Mayo Clinic Florida. Department of Neurology) ; Reinders, Marcel J. T. (Delft University of Technology. Delft Bioinformatics Lab) ; Uitti, Ryan J. (Mayo Clinic Florida. Department of Neurology) ; Tárraga, Lluís (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Maier, Wolfgang (DZNE, German Center for Neurodegenerative Diseases) ; Dols-Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Kawalia, Amit (University Hospital Cologne. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine) ; Dalmasso, Maria Carolina (Fundación Instituto Leloir-IIBBA-CONICET) ; Boada, Mercè (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Zettl, Uwe K. (University of Rostock. Department of Neurology) ; van Schoor, Natasja M. (Amsterdam Public Health Research Institute. Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Epidemiology and Biostatistics) ; Beekman, Marian (Leiden University Medical Center. Molecular Epidemiology) ; Allen, Mariet (Mayo Clinic Florida. Department of Neuroscience) ; Masliah, Eliezer (National Institute on Aging, National Institutes of Health. Laboratory of Neurogenetics) ; de Munain, Adolfo López (Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ; Pantelyat, Alexander (Johns Hopkins University Medical Center. Department of Neurology) ; Wszolek, Zbigniew K. (Mayo Clinic Florida. Department of Neurology) ; Ross, Owen A. (Mayo Clinic Florida. Department of Neuroscience) ; Dickson, Dennis W. (Mayo Clinic Florida. Department of Neuroscience) ; Graff-Radford, Neill R. (Mayo Clinic Florida. Department of Neurology) ; Knopman, David (Mayo Clinic Minnesota. Department of Neurology) ; Rademakers, Rosa (Mayo Clinic Florida. Department of Neuroscience) ; Lemstra, Afina W. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Pijnenburg, Yolande A. L. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Scheltens, Philip (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Gasser, Thomas (University of Tuebingen. Center of Neurology, Department of Neurodegenerative diseases, Hertie-Institute for Clinical Brain Research) ; Chinnery, Patrick F (University of Cambridge. MRC Mitochondrial Biology Unit) ; Hemmer, Bernhard (Munich Cluster for Systems Neurology (SyNergy)) ; Huisman, Martijn A. (VU University. Department of Sociology) ; Troncoso, Juan (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ; Moreno, Fermin (Cognitive Disorders Unit, Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ; Nohr, Ellen A. (University of Southern Denmark. Research Unit of Gynecology and Obstetrics, Department of Clinical Research) ; Sørensen, Thorkild I. A. (Bristol University. MRC Integrative Epidemiology Unit) ; Heutink, Peter (University of Tübingen. Hertie Institute for Clinical Brain Research) ; Sánchez-Juan, Pascual (IDIVAL) ; Posthuma, Danielle (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ; Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Christensen, Kaare (Odense University Hospital. Department of Clinical Genetics) ; Ertekin-Taner, Nilüfer (Mayo Clinic Florida. Department of Neurology) ; Scholz, Sonja W. (Johns Hopkins University Medical Center. Department of Neurology) ; Ramirez, Alfredo (University Hospital Cologne. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine) ; Ruiz, Agustín (Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED)) ; Slagboom, Eline (Dutch Society for Research on Ageing, Leiden, The Netherlands) ; van der Flier, Wiesje M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ; Holstege, Henne (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ; Universitat Autònoma de Barcelona
Department of Psychiatry, 2020 - 10.1007/s00401-019-02026-8
Acta Neuropathologica, Vol. 139 (january 2020) , p. 959-962  
7.
11 p, 4.2 MB Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis / Penas Pérez, Clara (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Maloof, M.E. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Stathias, V. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Long, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Tan, S.K. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences) ; Mier, J. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Fang, Y. (The Rockefeller University. Laboratory of Development Neurobiology) ; Valdes, C. (Florida International University. Computing and Information Sciences) ; Rodriguez-Blanco, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Chiang, C.M. (University of Texas Southwestern Medical Center. Simmons Comprehensive Cancer Center. Department of Biochemistry and Department of Pharmacology) ; Robbins, D.J. (University of Miami Miller School of Medicine. Department of Surgery) ; Liebl, D.J. (University of Miami Miller School of Medicine. Department of Surgery) ; Lee, J.K. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Hatten, M.E. (The Rockefeller University. Laboratory of Development Neurobiology) ; Clarke, J. (University of Nebraska. Department of Statistics) ; Ayad, N.G. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences. Center for Therapeutic Innovation. Sylvester Comprehensive Cancer Center. Miami Project to Cure Paralysis)
Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric brain tumor, medulloblastoma. [...]
2019 - 10.1038/s41467-019-10799-5
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 3028  
8.
13 p, 1.4 MB Genome-wide association meta-analysis of functional outcome after ischemic stroke / Söderholm, M. (Department of Neurology and Rehabilitation Medicine. Skåne University Hospital) ; Pedersen, A. (Department of Clinical Neuroscience. Institute of Neuroscience and Physiology. Sahlgrenska Academy. University of Gothenburg) ; Lorentzen, E. (Department of Neurology. Sahlgrenska University Hospital) ; Stanne, T.M. (Institute of Biomedicine) ; Bevan, S. (Bioinformatics Core Facility. University of Gothenburg) ; Olsson, M. (Institute of Biomedicine) ; Cole, J.W. ; Fernandez-Cadenas, I. (Institut d'Investigació Biomèdica Sant Pau) ; Hankey, G.J. (Medical School. The University of Western Australia, Perth; Department of Neurology) ; Jimenez-Conde, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Jood, K. (Department of Clinical Genetics and Genomics) ; Lee, J.M. (Department of Neurology. Washington University School of Medicine, St. Louis, MO) ; Lemmens, R. (Department of Neurosciences. Experimental Neurology. KU Leuven. University of Leuven) ; Levi, C. (School of Medicine and Public Health) ; Mitchell, B.D. (Priority Research Centre for Stroke and Traumatic Brain Injury. University of Newcastle) ; Norrving, B. (Department of Neurology and Rehabilitation Medicine. Skåne University Hospital) ; Rannikmäe, K. (Department of Medicine. University of Maryland) ; Rost, N.S. (Geriatric Research. Education. and Clinical Center. Veterans Affairs Medical Center) ; Rosand, J. (J. Philip Kistler Stroke Research Center. Department of Neurology. Massachusetts GeneralHospital. HarvardMedical School) ; Rothwell, P.M. (Broad Institute of MIT and Harvard) ; Scott, R. (Departments of Neurology and Health Evaluation Sciences. University of Virginia) ; Strbian, D. (Center for Genomic Medicine. Massachusetts General Hospital) ; Sturm, J.W. (Center for Brain and Disease Research. Laboratory of Neurobiology. VIB) ; Sudlow, C. (Department of Medicine. University of Maryland) ; Traylor, M. (Stroke Prevention Research Unit. Nuffield Department of Clinical Neurosciences. University of Oxford) ; Thijs, V. (Department of ClinicalNeurosciences. University of Cambridge) ; Tatlisumak, T. (Stroke Division. Florey Institute for Neuroscience and Mental Health. University of Melbourne) ; Woo, D. (Department of Neurology. Austin Health) ; Worrall, B.B. (Department of Neurology and Rehabilitation. University of Cincinnati. College of Medicine) ; Maguire, J.M. (HunterMedical Research Centre. PRC Stroke and Brain Injury) ; Lindgren, A. (Department of Neurology and Rehabilitation Medicine. Skåne University Hospital) ; Jern, C. (School of Life Sciences. University of Lincoln) ; Universitat Autònoma de Barcelona
ObjectiveTo discover common genetic variants associated with poststroke outcomes using a genome-wide association (GWA) study. MethodsThe study comprised 6,165 patients with ischemic stroke from 12 studies in Europe, the United States, and Australia included in the GISCOME (Genetics of Ischaemic Stroke Functional Outcome) network. [...]
2019 - 10.1212/WNL.0000000000007138
Neurology, Vol. 92 Núm. 12 (19 2019) , p. E1271-E1283  
9.
12 p, 544.9 KB Association of Apolipoprotein e with Intracerebral Hemorrhage Risk by Race/Ethnicity : A Meta-analysis / Marini, S. (Massachusetts General Hospital) ; Crawford, K. (Massachusetts General Hospital) ; Morotti, A. (Fondazione Mondino IRCCS, Pavia) ; Lee, M.J. (Massachusetts General Hospital) ; Pezzini, A. (Università degli Studi di Brescia) ; Moomaw, C.J. (University of Cincinnati) ; Flaherty, M.L. (University of Cincinnati) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roquer Gonzalez, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Jimenez Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soriano Tarraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Slowik, A. (Jagiellonian University Medical College, Kraków) ; Jagiella, J.M. (Jagiellonian University Medical College, Kraków) ; Pera, J. (Jagiellonian University Medical College, Kraków) ; Urbanik, A. (Jagiellonian University Medical College, Kraków) ; Pichler, A. (Jagiellonian University Medical College, Kraków) ; Hansen, B.M. (Lund University) ; McCauley, J.L. (John P. Hussman Institute for Human Genomics, Miami) ; Tirschwell, D.L. (University of Washington) ; Selim, Magdy (Beth Israel Deaconess Medical Center, Boston) ; Brown, D.L. (University of Michigan) ; Silliman, S.L. (University of Florida College of Medicine) ; Worrall, B.B. (University of Virginia Health System) ; Meschia, J.F. (Mayo Clinic, Jacksonville, Florida) ; Kidwell, C.S. (University of Arizona) ; Testai, F.D. (University of Illinois) ; Kittner, S.J. (University of Maryland School of Medicine) ; Schmidt, H. (Medical University of Graz) ; Enzinger, C. (Medical University of Graz) ; Deary, I.J. (University of Edinburgh) ; Rannikmae, K. (University of Edinburgh) ; Samarasekera, N. (University of Edinburgh) ; Salman, R.A.S. (University of Edinburgh) ; Sudlow, C.L. (University of Edinburgh) ; Klijn, C.J.M. (UMC Utrecht Brain Center Rudolf Magnus) ; Van Nieuwenhuizen, K.M. (UMC Utrecht Brain Center Rudolf Magnus) ; Fernandez Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Norrving, B. (Lund University) ; Lindgren, A. (Lund University) ; Goldstein, J.N. (Massachusetts General Hospital) ; Viswanathan, A. (Massachusetts General Hospital) ; Greenberg, S.M. (Massachusetts General Hospital) ; Falcone, G.J. (Yale University) ; Biffi, A. (Massachusetts General Hospital) ; Langefeld, C.D. (Wake Forest University, Winston-Salem, North Carolina) ; Woo, D. (University of Cincinnati College of Medicine) ; Rosand, J. (Massachusetts General Hospital) ; Anderson, C.D. (Massachusetts General Hospital) ; Universitat Autònoma de Barcelona
Importance: Genetic studies of intracerebral hemorrhage (ICH) have focused mainly on white participants, but genetic risk may vary or could be concealed by differing nongenetic coexposures in nonwhite populations. [...]
2019 - 10.1001/jamaneurol.2018.4519
JAMA Neurology, Vol. 76 Núm. 4 (april 2019) , p. 480-491  
10.
26 p, 3.5 MB A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs / Cho, In-Cheol (Rural Development Administration. National Institute of Animal Science) ; Park, Hee-Bok (Kongju National University. College of Industrial Sciences. Department of Animal Resources Science) ; Ahn, Jin Seop (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center) ; Han, Sang-Hyun (Jeju National University. Educational Science Research Institute) ; Lee, JaeBong (Chonbuk National University. Korea Zoonosis Research Institute) ; Lim, Hyun-Tae (Gyeongsang National University. College of Agriculture and Life Sciences) ; Yoo, Chae-Kyoung (Gyeongsang National University. Institute of Agriculture and Life Science.) ; Jung, Eun-Ji (Bio-Medical Science Co., Ltd) ; Kim, Dong-Hwan (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center) ; Sun, Wu-Sheng (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center) ; Ramayo-Caldas, Yuliaxis (Institut de Recerca i Tecnologia Agroalimentàries) ; Kim, Sang-Geum (Rural Development Administration. National Institute of Animal Science) ; Kang, Yong-Jun (Rural Development Administration. National Institute of Animal Science) ; Kim, YooKyung (Jeju National University. Educational Science Research Institute) ; Shin, Hyun-Sook (Rural Development Administration. National Institute of Animal Science) ; Seong, Pil-Nam (Rural Development Administration. National Institute of Animal Science) ; Hwang, In-Sul (Rural Development Administration. National Institute of Animal Science) ; Park, Beom-Young (Rural Development Administration. National Institute of Animal Science) ; Hwang, Seongsoo (Rural Development Administration. National Institute of Animal Science) ; Lee, Sung-Soo (Rural Development Administration. National Institute of Animal Science) ; Ryu, Youn-Chul (Jeju National University. Division of Biotechnology. SARI) ; Lee, Jun-Heon (Chungnam National University. Division of Animal and Dairy Science) ; Ko, MoonSuck (Rural Development Administration. National Institute of Animal Science) ; Lee, Kichoon (Ohio State University. College of Food Agricultural and Environmental Sciences) ; Andersson, Göran (Swedish University of Agricultural Sciences. Department of Animal Breeding and Genetics) ; Perez-Enciso, Miguel (Centre de Recerca en Agrigenòmica) ; Lee, JeongWoong (Korea Research Institute of Bioscience and Biotechnology. Biotherapeutics Translational Research Center)
Muscle development and lipid accumulation in muscle critically affect meat quality of livestock. However, the genetic factors underlying myofiber-type specification and intramuscular fat (IMF) accumulation remain to be elucidated. [...]
2019 - 10.1371/journal.pgen.1008279
PLoS Genetics, Vol. 15, Núm. 10 (October 2019) , art. e1008279  

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