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28 p, 5.4 MB BarkBase : Epigenomic Annotation of Canine Genomes / Megquier, Kate (Vertebrate Genomics, Broad Institute of MIT and Harvard, Cambridge.) ; Genereux, Diane P. (Broad Institute of MIT and Harvard) ; Hekman, Jessica (Broad Institute of MIT and Harvard) ; Swofford, Ross (Broad Institute of MIT and Harvard) ; Turner-Maier, Jason (Broad Institute of MIT and Harvard) ; Johnson, Jeremy (Broad Institute of MIT and Harvard) ; Alonso, Jacob (Broad Institute of MIT and Harvard) ; Li, Xue (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ; Morrill, Kathleen (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ; Anguish, Lynne J. (Cornell University. Baker Institute for Animal Health) ; Koltookian, Michele (Broad Institute of MIT and Harvard) ; Logan, Brittney (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ; Sharp, Claire R. (Murdoch University. School of Veterinary and Life Sciences) ; Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Lindblad-Toh, Kerstin (Uppsala University. Department of Medical Biochemistry & Microbiology) ; Meyers-Wallen, Vicki N. (Cornell University. Baker Institute for Animal Health) ; Hoffman, Andrew (Tufts University. Cummings School of Veterinary Medicine) ; Karlsson, Elinor K. (University of Massachusetts Medical School. Program in Molecular Medicine)
Dogs are an unparalleled natural model for investigating the genetics of health and disease, particularly for complex diseases like cancer. Comprehensive genomic annotation of regulatory elements active in healthy canine tissues is crucial both for identifying candidate causal variants and for designing functional studies needed to translate genetic associations into disease insight. [...]
2019 - 10.3390/genes10060433
Genes, Vol. 10 (june 2019)  

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