Resultats globals: 5 registres trobats en 0.02 segons.
Articles, 5 registres trobats
Articles 5 registres trobats  
9 p, 325.6 KB Nintedanib for the treatment of patients with refractory metastatic colorectal cancer (LUME-Colon 1) : a phase III, international, randomized, placebo-controlled study / Van Cutsem, E (Division of Digestive Oncology, University Hospitals Gasthuisberg Leuven and KU Leuven, Leuven, Belgium) ; Yoshino, T (Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan) ; Lenz, H J (Division of Medical Oncology, Norris Comprehensive Cancer Center, Los Angeles, USA) ; Lonardi, S (Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto - IRCCS, Padua) ; Falcone, A (Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy) ; Limón, M L (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Saunders, M (Department of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UK) ; Sobrero, A (Department of Medical Oncology, Azienda Ospedaliera San Martino, Genoa, Italy) ; Park, Y S (Department of Hematology and Oncology, Samsung Medical Center, Seoul, South Korea) ; Ferreiro, R (Hospital Universitario Ramón y Cajal (Madrid)) ; Hong, Y S (Department of Oncology, Asan Medical Center, Seoul, South Korea) ; Tomasek, J (Department of Complex Oncology Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic) ; Taniguchi, H (Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan) ; Ciardiello, F (Oncologia Medica, Seconda Università deli Studi di Napoli, Naples, Italy) ; Stoehr, J (Boehringer Ingelheim, Pharma GmbH & Co. KG, Biberach, Germany) ; Oum'Hamed, Z (Boehringer Ingelheim France S.A.S, Reims, France) ; Vlassak, S (SCS Boehringer Ingelheim Comm.V, Brussels, Belgium) ; Studeny, M (Division of Medicine/Clinical Development Department, Boehringer Ingelheim, Vienna, Austria) ; Argiles, G (Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
Angiogenesis is critical to colorectal cancer (CRC) growth and metastasis. Phase I/II studies have demonstrated the efficacy of nintedanib, a triple angiokinase inhibitor, in patients with metastatic CRC. [...]
2018 - 10.1093/annonc/mdy241
Annals of oncology, Vol. 29 (july 2018) , p. 1955-1963  
16 p, 1.5 MB Health-related Quality of Life in the Phase III LUME-Colon 1 Study : Comparison and Interpretation of Results From EORTC QLQ-C30 Analyses / Lenz, H.J. (Division of Medical Oncology. USC Norris Comprehensive Cancer Center) ; Argiles, Guillem (Vall d'Hebron Institut d'Oncologia) ; Yoshino, T. (Department of Gastroenterology and Gastrointestinal Oncology. National Cancer Center Hospital East) ; Lonardi, S. (Phase 1 Trial Unit and Medical Oncology Unit 1. Istituto Oncologico Veneto IRCCS) ; Falcone, A. (Department of Oncology. University of Pisa) ; Limón, M.L. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Sobrero, A. (Medical Oncology 1. Ospedale Policlinico San Martino IRCCS) ; Hastedt, C. (TA CNS Retinopathies Emerging Areas. Boehringer Ingelheim International GmbH) ; Peil, B. (Biostatistics and Data Sciences. Boehringer Ingelheim Pharma GmbH & Co. KG) ; Voss, F. (Biostatistics and Data Sciences. Boehringer Ingelheim Pharma GmbH & Co. KG) ; Griebsch, I. (TA Oncology. Boehringer Ingelheim International GmbH) ; Van Cutsem, E. (Digestive Oncology. University Hospitals Leuven and KULeuven) ; Universitat Autònoma de Barcelona
Based on European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) outputs from the LUME-Colon 1 study, we compared and discussed different statistical methods for evaluating health-related quality of life data in oncology clinical trials. [...]
2019 - 10.1016/j.clcc.2019.08.005
Clinical Colorectal Cancer, Vol. 18 Núm. 4 (december 2019) , p. 269-279.e5  
76 p, 1.7 MB A global perspective on carotenoids : metabolism, biotechnology, and benefits for nutrition and health / Rodríguez Concepción, Manuel (Centre de Recerca en Agrigenòmica) ; Ávalos, Javier (Universidad de Sevilla. Departmento de Genètica) ; Bonet, M. Luisa (Universitat de les Illes Balears. Laboratori de Biologia Molecular, Nutrició i Biotecnologia) ; Boronat i Margosa, Albert (Centre de Recerca en Agrigenòmica) ; Gómez Gómez, Lourdes (Universidad de Castilla-La Mancha. Instituto Botánico) ; Hornero-Mendez, Dámaso (Consejo Superior de Investigaciones Científicas. Instituto de la Grasa. Departamento de Fitoquímica de los Alimentos) ; Limón, M. Carmen (Universidad de Sevilla. Departmento de Genètica) ; Meléndez-Martínez, Antonio J. (Universidad de Sevilla. Nutrición y Bromatología, Toxicología y Medicina Legal) ; Olmedilla Alonso, Begoña (Consejo Superior de Investigaciones Científicas. Instituto de Ciencia y Tecnología de Alimentos y Nutrición) ; Paolo, Andreu (Universitat de les Illes Balears. Laboratori de Biologia Molecular, Nutrició i Biotecnologia) ; Ribot, Joan (Universitat de les Illes Balears. Laboratori de Biologia Molecular, Nutrició i Biotecnologia) ; Rodrigo, María J. (Institut d'Investigació Sanitària Illes Balears) ; Zacarías, Lorenzo (Institut d'Investigació Sanitària Illes Balears) ; Zhuj, Changfu (Institut d'Investigació Sanitària Illes Balears)
Carotenoids are lipophilic isoprenoid compounds synthesized by all photosynthetic organisms and some non-photosynthetic prokaryotes and fungi. With some notable exceptions, animals (including humans) do not produce carotenoids de novo but take them in their diets. [...]
2018 - 10.1016/j.plipres.2018.04.004
Progress in lipid research, Vol. 70 (April 2018) , p. 62-93  
9 p, 1023.2 KB Efficacy of trifluridine and tipiracil (TAS-102) versus placebo, with supportive care, in a randomized, controlled trial of patients with metastatic colorectal cancer from Spain : results of a subgroup analysis of the phase 3 RECOURSE trial / Longo Muñoz, Federico (Hospital Universitario Ramón y Cajal (Madrid)) ; Argilés Martínez, Guillem (Hospital Universitari Vall d'Hebron) ; Tabernero, Josep (Hospital Universitari Vall d'Hebron) ; Cervantes, A. (Universitat de València) ; Grávalos, Cristina (Hospital Universitario 12 de Octubre (Madrid)) ; Pericay, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Gil Calle, S. (Hospital Carlos Haya) ; Mizuguchi, Hirokazu (Taiho Oncology) ; Carrato, Alfredo (Hospital Universitario Ramón y Cajal (Madrid)) ; Limón, María Luisa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; García Carbonero, Rocio (Hospital Universitario 12 de Octubre (Madrid)) ; Universitat Autònoma de Barcelona
TAS-102 is a combination of the thymidine-based nucleoside analog trifluridine and the thymidine phosphorylase inhibitor tipiracil. Efficacy and safety of TAS-102 in patients with metastatic colorectal cancer (mCRC) refractory or intolerant to standard therapies were evaluated in the phase 3 RECOURSE trial. [...]
2017 - 10.1007/s12094-016-1528-7
Clinical & Translational Oncology, Vol. 19, Issue 2 (February 2017) , p. 227-235  
12 p, 730.0 KB Las ideas de los alumnos sobre la ciencia : una interpretación desde la psicología cognitiva / Pozo, J. A. (Universidad Autónoma de Madrid. Facultad de Psicología) ; Sanz, A. (Universidad Autónoma de Madrid. Facultad de Psicología) ; Gómez Crespo, M.A. (Universidad Autónoma de Madrid. Facultad de Psicología) ; Limón, M. (Universidad Autónoma de Madrid. Facultad de Psicología)
This paper deals with the psychological processes by which students' altemative ideas of scientific concepts arise.
1991 - 10.5565/rev/ensciencias.4689
Enseñanza de las ciencias, V. 9 n. 1 (1991) p. 83-94  

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