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Artículos, Encontrados 3 registros
Artículos Encontrados 3 registros  
1.
9 p, 3.8 MB Electrochemical genosensing of overexpressed GAPDH transcripts in breast cancer exosomes / Pallarès-Rusiñol, Arnau (Universitat Autònoma de Barcelona. Departament de Química) ; Lima Moura, Silio (Universitat Autònoma de Barcelona. Departament de Química) ; Martí, Mercè (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
Exosomes are receiving highlighted attention as new biomarkers for the detection of cancer since they are profusely released by tumor cells in different biological fluids. In this paper, the exosomes are preconcentrated from the serum by immunomagnetic separation (IMS) based on a CD326 receptor as a specific epithelial cancer-related biomarker and detected by glyceraldehyde-3-phosphate dehydrogenase (GAPDH) transcripts. [...]
2023 - 10.1021/acs.analchem.2c04773
Analytical chemistry, (January 2023)
2 documentos
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2.
7 p, 4.0 MB The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design / Lima Moura, Silio (Universitat Autònoma de Barcelona. Departament de Química) ; Pallarès-Rusiñol, Arnau (Universitat Autònoma de Barcelona. Departament de Química) ; Sappia, Luciano (Universitat Autònoma de Barcelona. Departament de Química) ; Martí, Mercè (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
This work addresses a biosensor combining the immunomagnetic separation and the electrochemical biosensing based on the intrinsic ALP activity of the exosomes. This approach explores for the first time two different types of biomarkers on exosomes, in a unique biosensing device combining two different biorecognition reaction: immunological and enzymatic. [...]
2022 - 10.1016/j.bios.2021.113826
Biosensors & bioelectronics, Vol. 198 (February 2022) , art. 113826  
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3.
21 p, 2.9 MB Matrix effect in the isolation of breast cancer- derived nanovesicles by immunomagnetic separation and electrochemical immunosensing- A comparative study / Lima Moura, Silio (Universitat Autònoma de Barcelona. Departament de Química) ; Martí, Mercè (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
Exosomes are cell-derived nanovesicles released into biological fluids, which are involved in cell-to-cell communication. The analysis of the content and the surface of the exosomes allow conclusions about the cells they are originating from and the underlying condition, pathology or disease. [...]
2020 - 10.3390/s20040965
Sensors (Basel, Switzerland), Vol. 20, issue 4 (2020) , art. 965  
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