Resultados globales: 19 registros encontrados en 0.02 segundos.
Artículos, Encontrados 18 registros
Documentos de investigación, Encontrados 1 registros
Artículos Encontrados 18 registros  1 - 10siguiente  ir al registro:
1.
20 p, 10.5 MB Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression / Zhang, Jun (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering (China)) ; Liu, Bing (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gu, Dan (Yangzhou University. Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses (China)) ; Hao, Yuan (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering (China)) ; Chen, Mo (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering (China)) ; Ma, Yue (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering (China)) ; Zhou, Xiaohui (University of Connecticut. Department of Pathobiology and Veterinary Science (USA)) ; Reverter i Cendrós, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Zhang, Yuanxing (Southern Marine Science and Engineering Guangdong Laboratory (China)) ; Wang, Qiyao (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering (China)) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
LuxR is a TetR family master quorum sensing (QS) regulator activating or repressing expression of hundreds of genes that control collective behaviors in Vibrios with underlying mechanism unknown. To illuminate how this regulator controls expression of various target genes, we applied ChIP-seq and DNase I-seq technologies. [...]
2021 - 10.1093/nar/gkab150
Nucleic acids research, Vol. 49, Issue 6 (April 2021) , p. 3274-3293  
2.
16 p, 903.0 KB Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology / Shi, Liu (University of Oxford) ; Winchester, Laura M. (University of Oxford) ; Liu, Benjamine Y. (University of Oxford) ; Killick, Richard (Maurice Wohl Institute Clinical Neuroscience Institute) ; Ribe, Elena M. (University of Oxford) ; Westwood, Sarah (University of Oxford) ; Baird, Alison L. (University of Oxford) ; Buckley, Noel J. (University of Oxford) ; Hong, Shengjun (University of Lübeck) ; Dobricic, Valerija (University of Lübeck) ; Kilpert, Fabian (University of Lübeck) ; Franke, Andre (Christian-Albrechts-University of Kiel) ; Kiddle, Steven (King's College London) ; Sattlecker, Martina (King's College London) ; Dobson, Richard (University College London) ; Cuadrado, Antonio ("Victor Babes" National Institute of Pathology) ; Hye, Abdul (Maurice Wohl Institute Clinical Neuroscience Institute) ; Ashton, Nicholas J. (University of Gothenburg) ; Morgan, Angharad R. (Cardiff University) ; Bos, Isabelle (VU University Medical Center) ; Vos, Stephanie J.B. (Maastricht University) ; ten Kate, Mara (VU University Medical Center) ; Scheltens, Philip (VU University Medical Center) ; Vandenberghe, Rik (University Hospital Leuven) ; Gabel, Silvy (Laboratory for Cognitive Neurology) ; Meersmans, Karen (Laboratory for Cognitive Neurology) ; Engelborghs, Sebastiaan (Department of Neurology, UZ Brussel, Brussels) ; De Roeck, Ellen E. (University of Antwerp) ; Sleegers, Kristel (Center for Molecular Neurology) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Blin, Olivier (Aix-Marseille Université) ; Richardson, Jill C. (Neurosciences Therapeutic Area, GlaxoSmithKline R&D, Stevenage) ; Bordet, Régis (University of Lille) ; Molinuevo, José L. (Barcelonaβeta Brain Research Center (BBRC)) ; Rami, Lorena (Barcelonaβeta Brain Research Center (BBRC)) ; Wallin, Anders (Sahlgrenska University Hospital) ; Kettunen, Petronella (University of Oxford) ; Tsolaki, Magda (Aristotle University of Thessaloniki) ; Verhey, Frans (Maastricht University) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Popp, Julius (University of Geneva) ; Peyratout, Gwendoline (University Hospital of Lausanne) ; Martinez-Lage, Pablo (CITA-Alzheimer Foundation, San Sebastian) ; Tainta, Mikel (Organización Sanitaria Integrada Goierri - Alto Urola, Osakidetza) ; Johannsen, Peter (Copenhagen University Hospital) ; Teunissen, Charlotte E. (Amsterdam University Medical Centers) ; Freund-Levi, Yvonne (Department of Psychiatry, Örebro Universitetssjukhus, Örebro) ; Frölich, Lutz (University of Heidelberg) ; Legido-Quigley, Cristina (Steno Diabetes Center Copenhagen) ; Barkhof, Frederik (UCL Institutes of Neurology and Healthcare Engineering) ; Blennow, Kaj (Sahlgrenska University Hospital) ; Rasmussen, Katrine Laura (University of Copenhagen) ; Nordestgaard, Børge Grønne (Copenhagen University Hospital) ; Frikke-Schmidt, Ruth (University of Copenhagen) ; Nielsen, Sune Fallgaard (Copenhagen University Hospital) ; Soininen, Hilkka (University of Eastern Finland) ; Vellas, Bruno (Univeriste Paul Sabatier) ; Kloszewska, Iwona (Medical University of Lodz) ; Mecocci, Patrizia (University of Perugia) ; Zetterberg, Henrik (UCL Institute of Neurology) ; Morgan, B. Paul (Cardiff University) ; Streffer, Johannes (UCB, Braine-l'Alleud, , formerly Janssen R&D, LLC. Beerse, Belgium at the time of study conduct) ; Visser, Pieter Jelle (Karolinska Institutet) ; Bertram, Lars (University of Oslo) ; Nevado-Holgado, Alejo (University of Oxford) ; Lovestone, Simon (University of Oxford) ; Universitat Autònoma de Barcelona
Previous studies suggest that Dickkopf-1 (DKK1), an inhibitor of Wnt signaling, plays a role in amyloid-induced toxicity and hence Alzheimer's disease (AD). However, the effect of DKK1 expression on protein expression, and whether such proteins are altered in disease, is unknown. [...]
2020 - 10.3233/JAD-200208
Journal of Alzheimer's disease, Vol. 77 (september 2020) , p. 1353-1368  
3.
10 p, 3.6 MB Plant buffering against the high-light stress-induced accumulation of CsGA2ox8 transcripts via alternative splicing to finely tune gibberellin levels and maintain hypocotyl elongation / Liu, Bin (Centre de Recerca en Agrigenòmica) ; Zhao, Shuo (Shanghai Jiao Tong University. School of Agriculture and Biology) ; Li, Pengli (Shanghai Jiao Tong University. School of Agriculture and Biology) ; Yin, Yilu (Shanghai Jiao Tong University. School of Agriculture and Biology) ; Niu, Qingliang (Shanghai Jiao Tong University. School of Agriculture and Biology) ; Yan, Jinqiang (Guangdong Academy of Agricultural Sciences) ; Huang, Danfeng (Shanghai Jiao Tong University. School of Agriculture and Biology)
In plants, alternative splicing (AS) is markedly induced in response to environmental stresses, but it is unclear why plants generate multiple transcripts under stress conditions. In this study, RNA-seq was performed to identify AS events in cucumber seedlings grown under different light intensities. [...]
2021 - 10.1038/s41438-020-00430-w
Horticulture research, Vol. 8, art. 2 (Jan. 2021)  
4.
15 p, 1.2 MB Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [ 18 F]-Flutemetamol PET Scan Result / Westwood, Sarah (University of Oxford. Department of Psychiatry) ; Baird, Alison L. (Department of Psychiatry, University of Oxford) ; Hye, Abdul (Biomedical Research Unit for Dementia, NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust) ; Ashton, Nicholas J. (Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg) ; Nevado-Holgado, Alejo J. (Department of Psychiatry, University of Oxford) ; Anand, Sneha N. (Department of Psychiatry, University of Oxford) ; Liu, Benjamine (Department of Psychiatry, University of Oxford) ; Newby, Danielle (Department of Psychiatry, University of Oxford) ; Bazenet, Chantal (Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London) ; Kiddle, Steven J. (MRC Biostatistics Unit, Cambridge Biomedical Campus, Cambridge Institute of Public Health, University of Cambridge) ; Ward, Malcolm (Proteomics Facility, Institute of Psychiatry, Psychology & Neuroscience, King's College London) ; Newton, Ben (GE Healthcare Life Sciences Core Imaging) ; Desai, Keyur (Biosciences, GE Global Research) ; Tan Hehir, Cristina (Biosciences, GE Global Research) ; Zanette, Michelle (GE Healthcare Life Sciences Core Imaging) ; Galimberti, Daniela (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ; Parnetti, Lucilla (Center for Memory Disorders and Laboratory of Clinical Neurochemistry, Neurology Clinic, University of Perugia) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Baker, Susan (Janssen Neuroscience Research & Development) ; Narayan, Vaibhav A. (Janssen Neuroscience Research & Development) ; van der Flier, Wiesje M. (Department of Epidemiology and Biostatistics, VU University Medical Center) ; Scheltens, Philip (Department of Neurology, Alzheimer Centre, Amsterdam Neuroscience, VU University Medical Center) ; Teunissen, Charlotte E. (Department of Clinical Chemistry, Neurochemistry Lab and Biobank, Amsterdam Neuroscience, VU University Medical Center) ; Visser, Pieter Jelle (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Lovestone, Simon (Department of Psychiatry, University of Oxford) ; Universitat Autònoma de Barcelona
Background: Blood biomarkers may aid in recruitment to clinical trials of Alzheimer's disease (AD) modifying therapeutics by triaging potential trials participants for amyloid positron emission tomography (PET) or cerebrospinal fluid (CSF) Aβ and tau tests. [...]
2018 - 10.3389/fnagi.2018.00409
Frontiers in aging neuroscience, Vol. 10 (december 2018)  
5.
28 p, 7.6 MB Critical role for a promoter discriminator in RpoS control of virulence in Edwardsiella piscicida / Yin, Kaiyu (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Guan, Yunpeng (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Ma, Ruiqing (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Wei, Lifan (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Liu, Bing (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Liu, Xiaohong (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Zhou, Xiangshan (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Ma, Yue (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Zhang, Yuanxing (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Waldor, M.K. (Harvard Medical School) ; Wang, Qiyao (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Edwardsiella piscicida is a leading fish pathogen that causes significant economic loses in the aquaculture industry. The pathogen depends on type III and type VI secretion systems (T3/T6SS) for growth and virulence in fish and the expression of both systems is controlled by the EsrB transcription activator. [...]
2018 - 10.1371/journal.ppat.1007272
PLoS pathogens, Vol. 14 issue 8 (2018) , art. e1007272  
6.
13 p, 2.3 MB A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25 / Liu, Bing (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sureda-Gómez, Marta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Zhen, Yang (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Amador, Virginia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
USP25 deubiquitinating enzyme is a key member of the ubiquitin system, which acts as a positive regulator of the Wnt/β-catenin signaling by promoting the deubiquitination and stabilization of tankyrases. [...]
2018 - 10.1038/s41467-018-07510-5
Nature communications, Vol. 9 (2018) , art. 4973  
7.
10 p, 6.7 MB Structural analysis and evolution of specificity of the SUMO UFD E1-E2 interactions / Liu, Bing (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lois, L. Maria (Centre de Recerca en Agrigenòmica) ; Reverter i Cendrós, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
SUMO belongs to the ubiquitin-like family (UbL) of protein modifiers. SUMO is conserved among eukaryotes and is essential for the regulation of processes such as DNA damage repair, transcription, DNA replication and mitosis. [...]
2017 - 10.1038/srep41998
Scientific reports (Nature Publishing Group), Vol. 7 (February 2017) , art. 41998  
8.
9 p, 1.3 MB Selection footprints reflect genomic changes associated with breeding efforts in 56 cucumber inbred lines / Liu, Bin (China Agricultural University. Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops) ; Guan, Dailu (Centre de Recerca en Agrigenòmica) ; Zhai, Xuling (China Agricultural University. Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops) ; Yang, Sen (China Agricultural University. Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops) ; Xue, Shudan (China Agricultural University. Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops) ; Chen, Shuying (China Agricultural University. Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops) ; Huang, Jing (Purdue University. Department of Agronomy (USA)) ; Ren, Huazhong (China Agricultural University. Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops) ; Liu, Xingwang (China Agricultural University. Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops)
Cucumber selective breeding over recent decades has dramatically increased productivity and quality, but the genomic characterizations and changes associated with this breeding history remain unclear. [...]
2019 - 10.1038/s41438-019-0209-4
Horticulture research, Vol. 6 (November 2019) , art. 127  
9.
10 p, 1.6 MB The genome of woodland strawberry (Fragaria vesca) / Shulaev, Vladimir (University of North Texas. Department of Biological Sciences) ; Sargent, Daniel J. (East Malling Research) ; Crowhurst, Ross N. (New Zealand Institute for Plant and Food Research Limited) ; Mockler, Todd C. (Oregon State University. Center for Genome Research and Biocomputing) ; Folkerts, Otto (Chromatin Inc.) ; Delcher, Arthur L. (University of Maryland. Center for Bioinformatics and Computational Biology) ; Jaiswal, Pankaj (Oregon State University. Department of Botany and Plant Pathology) ; Mockaitis, Keithanne (Indiana University. Center for Genomics and Bioinformatics) ; Liston, Aaron (Oregon State University. Department of Botany and Plant Pathology) ; Mane, Shrinivasrao P. (Virginia Bioinformatics Institute) ; Burns, Paul (Joint Georgia Tech and Emory Wallace H. Coulter. Department of Biomedical Engineering) ; Davis, Thomas M. (University of New Hampshire. Department of Biological Sciences) ; Slovin, Janet P. (Henry Wallace Beltsville Agricultural Research Center) ; Bassil, Nahla (National Clonal Germplasm Repository) ; Hellens, Roger P. (New Zealand Institute for Plant and Food Research Limited) ; Evans, Clive (State University. Virginia Bioinformatics Institute) ; Harkins, Tim (Roche Diagnostics. Roche Applied Science) ; Kodira, Chinnappa (Roche Diagnostics. Roche Applied Science) ; Desany, Brian (Roche Diagnostics. Roche Applied Science) ; Crasta, Oswald R. (Chromatin Inc.) ; Jensen, Roderick V. (Virginia Tech. Department of Biological Sciences) ; Allan, Andrew C. (New Zealand Institute for Plant and Food Research Limited) ; Michael, Todd P. (State University of New Jersey. Waksman Institute of Microbiology) ; Setubal, Joao Carlos (Virginia Tech. Department of Computer Science) ; Celton, Jean-Marc (University of the Western Cape. Department of Biotechnology) ; Rees, D. Jasper G. (University of the Western Cape. Department of Biotechnology) ; Williams, Kelly P. (State University. Virginia Bioinformatics Institute) ; Holt, Sarah H. (Institute for Sustainable and Renewable Resources) ; Rojas, Juan Jairo (State University. Virginia Polytechnic Institute. Department of Horticulture) ; Chatterjee, Mithu (University of Florida. Graduate Program for Plant Molecular and Cellular Biology) ; Liu, Bo (University of New Hampshire. Department of Biological Sciences) ; Silva, Herman (University of Chile. Millennium Nucleus in Plant Cell Biotechnology) ; Meisel, Lee (Universidad Andres Bello. Millennium Nucleus in Plant Cell Biotechnology) ; Adato, Avital (Weizmann Institute of Science. Department of Plant Sciences) ; Filichkin, Sergei A. (Oregon State University. Center for Genome Research and Biocomputing) ; Troggio, Michela (Foundation Edmund Mach. Istituto Agrario San Michele all'Adige () ; Viola, Roberto (Istituto Agrario San Michele all'Adige (IASMA). Research and Innovation Centre. Foundation Edmund Mach) ; Ashman, Tia-Lynn (University of Pittsburgh. Department of Biological Sciences) ; Wang, Hao (University of Georgia. Department of Genetics) ; Dharmawardhana, Palitha (Oregon State University. Department of Botany and Plant Pathology) ; Elser, Justin (Oregon State University. Department of Botany and Plant Pathology) ; Raja, Rajani (Oregon State University. Department of Botany and Plant Pathology) ; Priest, Henry D. (Oregon State University. Center for Genome Research and Biocomputing) ; Bryant, Douglas W. (Oregon State University. Center for Genome Research and Biocomputing) ; Fox, Samuel E. (Oregon State University. Center for Genome Research and Biocomputing) ; Givan, Scott A. (Oregon State University. Center for Genome Research and Biocomputing) ; Wilhelm, Larry J. (Oregon State University. Center for Genome Research and Biocomputing) ; Naithani, Sushma (Oregon State University. Department of Horticulture) ; Christoffels, Alan (University of the Western Cape. South African National Bioinformatics Institute) ; Salama, David Y. (University of Florida. Horticultural Sciences Department) ; Carter, Jade (Indiana University. Center for Genomics and Bioinformatics) ; Girona, Elena L. (East Malling Research) ; Zdepski, Anna (State University of New Jersey. Waksman Institute of Microbiology) ; Wang, Wenqin (State University of New Jersey. Waksman Institute of Microbiology) ; Kerstetter, Randall A (State University of New Jersey. Waksman Institute of Microbiology) ; Schwab, Wilfried (Technical University München. Biotechnology of Natural Products) ; Korban, Schuyler S. (University of Illinois. Department of Natural Resources and Environmental Sciences) ; Davik, Jahn (Norwegian Institute for Agricultural and Environmental Research. Genetics and Biotechnology) ; Monfort Vives, Amparo (Centre de Recerca en Agrigenòmica) ; Denoyes-Rothan, Beatrice (Institut National de la Recherche Agronomique. Unité de Recherche des Espèces Fruitières) ; Arús i Gorina, Pere (Centre de Recerca en Agrigenòmica) ; Mittler, Ron (University of North Texas. Department of Biological Sciences) ; Flinn, Barry (Institute for Sustainable and Renewable Resources. Institute for Advanced Learning and Research) ; Aharoni, Asaph (Universidad Andres Bello. Millennium Nucleus in Plant Cell Biotechnology. Centro de Biotecnología Vegetal.) ; Bennetzen, Jeffrey L. (University of Georgia. Department of Genetics) ; Salzberg, Steven L. (University of Maryland. Center for Bioinformatics and Computational Biology) ; Dickerman, Allan W (State University. Virginia Bioinformatics Institute. Virginia Polytechnic Institute) ; Velasco, Riccardo (Foundation Edmund Mach. Istituto Agrario San Michele all'Adige) ; Borodovsky, Mark (Georgia Tech. School of Computational Science and Engineering) ; Veilleux, Richard E. (State University. Virginia Polytechnic Institute. Department of Horticulture) ; Folta, Kevin M. (University of Florida. Graduate Program for Plant Molecular and Cellular Biology)
The woodland strawberry, Fragaria vesca (2n = 2x = 14), is a versatile experimental plant system. This diminutive herbaceous perennial has a small genome (240 Mb), is amenable to genetic transformation and shares substantial sequence identity with the cultivated strawberry (Fragaria Ã- ananassa) and other economically important rosaceous plants. [...]
2011 - 10.1038/ng.740
Nature genetics, Vol. 43, Issue 2 (February 2011) , p. 109-116  
10.
30 p, 3.1 MB Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution / Liu, Bing (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Lois, L. Maria (Centre de Recerca en Agrigenòmica) ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
SUMOylation of proteins involves the concerted action of the E1-activating enzyme, E2-conjugating enzyme and E3-ligases. An essential discrimination step in the SUMOylation pathway corresponds to the initial interaction between E1 ubiquitin-fold domain (UFD) and E2 enzymes. [...]
2019 - 10.1042/BCJ20190232
Biochemical Journal, Vol. 476, Issue 14 (July 2019) , p. 2127-2139  

Artículos : Encontrados 18 registros   1 - 10siguiente  ir al registro:
Documentos de investigación Encontrados 1 registros  
1.
213 p, 14.7 MB Structure insights into the autoinhibitory mechanism of the deubiquitinating enzyme USP25 and into the SUMO E1-E2 protein-protein recognition / Liu, Bing ; Reverter Cendrós, David, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
La ubiquitinació i la SUMOilació són dos de les modificacions post-traduccionals més estudiades (PTM). En aquesta tesi, ens hem centrat en estudiar USP25, USP28 i en el reconeixement proteïna-proteïna dels enzims SUMO E1-E2 d'aquestes dues vies PTM. [...]
Ubiquitination and SUMOylation are of the most studied post-translational modifications (PTMs). Here, we focus on USP25, USP28, and the SUMO E1-E2 protein-protein recognition in these two PTM pathways. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  

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