Resultats globals: 3 registres trobats en 0.01 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
16 p, 3.5 MB Conservation and variability of hepatitis B core at different chronic hepatitis stages / Yll, Marçal ; Cortese, Maria Francesca ; Guerrero-Murillo, Mercedes ; Orriols, Gerard ; Gregori, Josep ; Casillas, Rosario ; González, Carolina ; Sopena, Sara ; Godoy, Cristina ; Vila, Marta ; Tabernero, David ; Quer, Josep ; Rando, Ariadna ; Lopez-Martinez, Rosa ; Esteban, Rafael ; Riveiro-Barciela, Mar ; Buti, Maria ; Rodriguez-Frias, Francisco
Since it is currently not possible to eradicate hepatitis B virus (HBV) infection with existing treatments, research continues to uncover new therapeutic strategies. HBV core protein, encoded by the HBV core gene (HBC), intervenes in both structural and functional processes, and is a key protein in the HBV life cycle. [...]
2020 - 10.3748/wjg.v26.i20.2584
World Journal of Gastroenterology, Vol. 26 (may 2020) , p. 2584-2598  
2.
14 p, 1.3 MB Detection of hyper-conserved regions in hepatitis B virus X gene potentially useful for gene therapy / González, Carolina (Hospital Universitari Vall d'Hebron) ; Tabernero, David (Hospital Universitari Vall d'Hebron) ; Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron) ; Gregori i Font, Josep (Roche Diagnostics SL) ; Casillas, Rosario (Hospital Universitari Vall d'Hebron) ; Riveiro Barciela, Mar (Universitat Autònoma de Barcelona. Departament de Medicina) ; Godoy, Cristina (Hospital Universitari Vall d'Hebron) ; Sopena, Sara (Hospital Universitari Vall d'Hebron) ; Rando, Ariadna (Hospital Universitari Vall d'Hebron) ; Yll, Marçal (Hospital Universitari Vall d'Hebron) ; Lopez Martinez, Rosa (Hospital Universitari Vall d'Hebron) ; Quer, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteban, Rafael (Esteban Mur) (Universitat Autònoma de Barcelona. Departament de Medicina) ; Buti, Maria (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodriguez-Frias, Francisco (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
To detect hyper-conserved regions in the hepatitis B virus (HBV) X gene (HBX) 5' region that could be candidates for gene therapy. The study included 27 chronic hepatitis B treatment-naive patients in various clinical stages (from chronic infection to cirrhosis and hepatocellular carcinoma, both HBeAg-negative and HBeAg-positive), and infected with HBV genotypes A-F and H. [...]
2018 - 10.3748/wjg.v24.i19.2095
World Journal of Gastroenterology, Vol. 24 (may 2018) , p. 2095-2107  
3.
7 p, 339.5 KB Application of a diagnostic algorithm for the rare deficient variant Mmalton of alpha-1-antitrypsin deficiency : a new approach / Belmonte, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barrecheguren Fernández, Miriam (Hospital Universitari Vall d'Hebron) ; López-Martínez, Rosa M (Hospital Universitari Vall d'Hebron) ; Esquinas, Cristina (Hospital Universitari Vall d'Hebron) ; Rodríguez, Esther (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ; Miravitlles, Marc (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ; Rodriguez-Frias, Francisco (CIBER of Liver and Digestive Diseases. Instituto Nacional de Salud Carlos III) ; Universitat Autònoma de Barcelona
Alpha-1-antitrypsin deficiency (AATD) is associated with a high risk for the development of early-onset emphysema and liver disease. A large majority of subjects with severe AATD carry the ZZ genotype, which can be easily detected. [...]
2016 - 10.2147/COPD.S115940
International journal of COPD, Vol. 11, Num. 1 (October 2016) , p. 2535-2541  

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