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20 p, 3.7 MB Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation / Li, Yang (Hebei Normal University) ; Shi, Zhenzhen (Kansas State University. Department of Anatomy and Physiology) ; Radauer-Preiml, Isabella (University of Salzburg. Department of Molecular Biology) ; Andosch, Ancuela (University of Salzburg. Department of Molecular Biology) ; Casals Mercadal, Eudald (Vall d'Hebron Institut de Recerca) ; Luetz-Meindl, Ursula (University of Salzburg. Department of Molecular Biology) ; Cobaleda-Siles, Macarena (Vall d'Hebron Institut de Recerca) ; Lin, Zhoumeng (Kansas State University. Department of Anatomy and Physiology) ; Jaberi-Douraki, Majid (Kansas State University. Department of Anatomy and Physiology) ; Italiani, Paola (National Research Council) ; Horejs-Hoeck, Jutta (University of Salzburg. Department of Molecular Biology) ; Himly, Martin (University of Salzburg. Department of Molecular Biology) ; Monteiro-Riviere, Nancy A. (Kansas State University. Department of Anatomy and Physiology) ; Duschl, Albert (University of Salzburg. Department of Molecular Biology) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Boraschi, Diana (National Research Council)
Nanoparticles (NPs) are easily contaminated by bacterial endotoxin (lipopolysaccharide [LPS]). The presence of LPS can be responsible for many immune/inflammatory effects attributed to NPs. In this study, we examined the effects of LPS adsorption on the NP surface on the formation of a biocorona in biological fluids and on the subsequent inflammation-inducing activity of NPs. [...]
2017 - 10.1080/17435390.2017.1401142
Nanotoxicology, Vol. 11, Issue 9-10 (December 2017) , p. 1157-1175  

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