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14 p, 654.2 KB Recent Positive Selection Has Acted on Genes Encoding Proteins with More Interactions within the Whole Human Interactome / Luisi, Pierre (Universitat Pompeu Fabra-CSIC. Institute of Evolutionary Biology) ; Alvarez-Ponce, David (Universitat Pompeu Fabra-CSIC. Institute of Evolutionary Biology) ; Pybus, Marc (Universitat Pompeu Fabra-CSIC. Institute of Evolutionary Biology) ; Fares, Mario A. (University of Dublin. Smurfit Institute of Genetics) ; Bertranpetit, Jaume (Universitat Pompeu Fabra-CSIC. Institute of Evolutionary Biology) ; Laayouni, Hafid (Universitat Autonòma de Barcelona. Departament de Genètica i de Microbiologia)
Genes vary in their likelihood to undergo adaptive evolution. The genomic factors that determine adaptability, however, remain poorly understood. Genes function in the context of molecular networks, with some occupying more important positions than others and thus being likely to be under stronger selective pressures. [...]
2015 - 10.1093/gbe/evv055
Genome Biology and Evolution, Vol. 7, issue 4 (april 2015) , p. 1141-1154  

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