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Articles 1 records found  
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19 p, 3.2 MB Glioblastoma Cells Counteract PARP Inhibition through Pro-Survival Induction of Lipid Droplets Synthesis and Utilization / Majuelos-Melguizo, Jara (Universidad Autónoma de Madrid. Departamento de Bioquímica) ; Rodríguez-Vargas, José Manuel (Instituto de Parasitología y Biomedicina "López-Neyra") ; Martínez-López, Nuria (Newcastle University. Institute for Cell and Molecular Biosciences) ; Delgado-Bellido, Daniel (Instituto de Parasitología y Biomedicina "López-Neyra") ; García-Díaz, Ángel (Instituto de Parasitología y Biomedicina "López-Neyra") ; Yuste, Victor J.. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; García-Macía, Marina (Newcastle University. Institute of Cellular Medicine) ; López, Laura M. (Instituto de Parasitología y Biomedicina "López-Neyra") ; Singh, Rajat (Albert Einstein College of Medicine. Department of Molecular Pharmacology) ; Oliver, F. J. (Instituto de Parasitología y Biomedicina "López-Neyra") ; Universitat Autònoma de Barcelona. Institut de Neurociències
Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults and one of the most aggressive cancers. The use of Poly ADP-Ribose Polymerase (PARP) inhibitors is being expanded as therapeutic alternative in multiple types of cancer beyond BRCA1/2 mutant breast and ovarian cancer. [...]
2022 - 10.3390/cancers14030726
Cancers, Vol. 14 Núm. 3 (january 2022)  
Detailed record - Creative Commons

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