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10 p, 2.2 MB A European multicentre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts / Hayes, A. (University of Oxford) ; Nguyen, D. (University of Oxford) ; Andersson, M. (John Radcliffe Hospital (Oxford, Regne Unit)) ; Antón, Andrés (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bailly, Jean-Luc (Université Clermont Auvergne) ; Beard, S. (National Infection Service, Public Health England) ; Benschop, Kimberley S. M (National Institute for Public Health and the Environment (RIVM), The Netherlands.) ; Berginc, N. (National Laboratory of Health, Environment and Food, Ljubljana, Slovenia.) ; Blomqvist, S. (National Institute for Health and Welfare, Finland.) ; Cunningham, E. (St. Thomas' Hospital, London, UK.) ; Davis, D. (Great Ormond Street Hospital for Children (Londres)) ; Dembinski, J. L. (Norwegian Institute of Public Health) ; Diedrich, S. (Robert Koch Institute, Berlin, Germany.) ; Dudman, Susanne (University of Oslo) ; Dyrdak, R. (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Eltringham, G. J. A. (Freeman Hospital, Newcastle Upon Tyne, UK.) ; Gonzales-Goggia, S. (National Infection Service, Public Health England) ; Gunson, R. (Glasgow Royal Infirmary) ; Howson-Wells, H. C. (Nottingham University Hospitals NHS Trust (Regne Unit)) ; Jääskeläinen, A. J. (Helsinki University Hospital (Finlàndia)) ; López-Labrador, F. X. (Fundació per al Foment de la Investigació Sanitària i Biomèdica de la Comunitat Valenciana (Fisabio)) ; Maier, M. (Leipzig University Hospital) ; Majumdar, M. (The National Institute for Biological Standards and Control, Hertfordshire, UK.) ; Midgley, S. (Statens Serum Institut, Copenhagen, Denmark.) ; Mirand, A. (CHU Clermont-Ferrand) ; Morley, U. (University College Dublin) ; Nordbø, S. A. (St Olav's University Hospital) ; Oikarinen, S. (Tampere University, Finland.) ; Osman, H. (Heartlands Hospital, Birmingham, UK.) ; Papa, A. (Aristotle University of Thessaloniki) ; Pellegrinelli, L. (University of Milan) ; Piralla, A. (Fondazione IRCCS Policlinico San Matteo, Pavia.) ; Rabella, Núria (Institut d'Investigació Biomèdica Sant Pau) ; Richter, Jan (Cyprus Institute of Neurology and Genetics) ; Smith, M. (King's College Hospital NHS Foundation Trust) ; Söderlund Strand, A. (Lund University Hospital, Sweden.) ; Templeton, K. (Royal Infirmary of Edinburgh) ; Vipond, B. (Southmead Hospital, Bristol, UK.) ; Vuorinen, T. (Turku University Hospital (Finlàndia)) ; Williams, C. (Royal Oldham Hospital, UK.) ; Wollants, E. (REGA Institute, Leuven, Belgium.) ; Zakikhany, K. (Katherina Zakikhany-Gilg, Public Health Agency of Sweden) ; Fischer, T. K. (Statens Serum Institut, Copenhagen, Denmark.) ; Harvala, H. (NHS Blood and Transplant, UK.) ; Simmonds, Peter (University of Oxford) ; Universitat Autònoma de Barcelona
Polymerase chain reaction (PCR) detection has become the gold standard for diagnosis and typing of enterovirus (EV) and human parechovirus (HPeV) infections. Its effectiveness depends critically on using the appropriate sample types and high assay sensitivity as viral loads in cerebrospinal fluid samples from meningitis and sepsis clinical presentation can be extremely low. [...]
2020 - 10.1002/jmv.25659
Journal of Medical Virology, Vol. 92 (january 2020) , p. 1065-1074  

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