Resultados globales: 7 registros encontrados en 0.02 segundos.
Artículos, Encontrados 7 registros
Artículos Encontrados 7 registros  
1.
18 p, 1.0 MB An adaptive phase II/III safety and efficacy randomized controlled trial of single day or three-day fixed-dose albendazole-ivermectin co-formulation versus albendazole for the treatment of Trichuris trichiura and other STH infections. ALIVE trial protocol / Krolewiecki, Alejandro J (Instituto de Investigaciones de Enfermedades Tropicales. Universidad Nacional de Salta) ; Enbiale, Wendemagegn (Department of Dermatology. Amsterdam Institute for Infection and Immunity. Academic Medical Centre) ; Gandasegui, Javier (Barcelona Institute for Global Health (ISGlobal)) ; van Lieshout, Lisette (Department of Parasitology. Centre of Infectious Diseases. Leiden University Medical Centre (LUMC)) ; Kepha, Stella (Eastern and Southern Africa Centre of International Parasite Control. Kenya Medical Research Institute (KEMRI)) ; Messa Junior, Augusto (Centro de Investigação em Saúde de Manhiça (CISM)) ; Bengtson, Michel (Department of Parasitology. Centre of Infectious Diseases. Leiden University Medical Centre (LUMC)) ; Gelaye, Woyneshet (College of Medicine and Health Science. Bahir Dar University) ; Escola, Valdemiro (Centro de Investigação em Saúde de Manhiça (CISM)) ; Martinez-Valladares, María (Universidad de León. Facultad de Veterinaria. Departamento de Sanidad Animal) ; Cambra-Pellejà, María (Universidad de León. Facultad de Veterinaria. Departamento de Sanidad Animal) ; Algorta, Jaime (Liconsa SA) ; Martí-Soler, Helena (Barcelona Institute for Global Health (ISGlobal)) ; Fleitas, Pedro (Universidad Nacional de Salta. Instituto de Investigaciones de Enfermedades Tropicales) ; Ballester, Maria Rosa (Institut d'Investigació Biomèdica Sant Pau) ; Doyle, Stephen R. (Wellcome Trust Sanger Institute (Regne Unit)) ; Williams, Nana Aba (Barcelona Institute for Global Health (ISGlobal)) ; Legarda, Almudena (Barcelona Institute for Global Health (ISGlobal)) ; Mandomando, Inacio (Centro de Investigação em Saúde de Manhiça (CISM)) ; Mwandawiro, Charles (Eastern and Southern Africa Centre of International Parasite Control. Kenya Medical Research Institute (KEMRI)) ; Muñoz, José (Barcelona Institute for Global Health (ISGlobal))
Background: Soil-transmitted helminths (STH) are targeted for control through mass drug-administration campaigns to prevent morbidity affecting at-risk groups in endemic regions. Although broadly successful, the use of albendazole and mebendazole achieved variable progress, with deficiencies against Trichuris trichiura and a predictable low efficacy against Strongyloides stercoralis. [...]
2022 - 10.12688/gatesopenres.13615.1
Gates Open Research, Vol. 6 (2022) , p. 62  
2.
17 p, 9.6 MB Gene dysregulation in acute HIV-1 infection - early transcriptomic analysis reveals the crucial biological functions affected / Parker, Erica (University of Western Australia) ; Judge, Melinda A. (University of Western Australia) ; Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fuente-Soro, Laura (Hospital Clínic i Provincial de Barcelona) ; Jairoce, Chenjerai (Centro de Investigação em Saúde da Manhiça (CISM)) ; Carter, Kim W. (Telethon Kids Institute) ; Anderson, Denise (Telethon Kids Institute) ; Mandomando, Inácio (Centro de Investigação em Saúde da Manhiça (CISM)) ; Clifford, Holly D. (Telethon Kids Institute) ; Naniche, Denise (Hospital Clínic i Provincial de Barcelona) ; Le Souëf, Peter Neils (Telethon Kids Institute) ; Universitat Autònoma de Barcelona
Transcriptomic analyses from early human immunodeficiency virus (HIV) infection have the potential to reveal how HIV causes widespread and lasting damage to biological functions, especially in the immune system. [...]
2023 - 10.3389/fcimb.2023.1074847
Frontiers in cellular and infection microbiology, Vol. 13 (april 2023)  
3.
9 p, 2.8 MB IP-10 Levels as an Accurate Screening Tool to Detect Acute HIV Infection in Resource-Limited Settings / Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Casellas, Aina (Hospital Clínic i Provincial de Barcelona) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Alonso, Sergi (Hospital Clínic i Provincial de Barcelona) ; Parker, Erica (School of Paediatrics and Child Health, University of Western Australia) ; Fuente-Soro, Laura (Hospital Clínic i Provincial de Barcelona) ; Jairoce, Chenjerai (Centro de Investigação em Saúde da Manhiça (CISM)) ; Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ; Blanco, Julià (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Naniche, Denise (Hospital Clínic i Provincial de Barcelona)
Acute HIV infection (AHI) is the period prior to seroconversion characterized by high viral replication, hyper-transmission potential and commonly, non-specific febrile illness. AHI detection requires HIV-RNA viral load (VL) determination, which has very limited access in low-income countries due to restrictive costs and implementation constraints. [...]
2017 - 10.1038/s41598-017-08218-0
Scientific reports, Vol. 7 (august 2017)  
4.
13 p, 4.6 MB Dynamics of CD4 and CD8 T-Cell Subsets and Inflammatory Biomarkers during Early and Chronic HIV Infection in Mozambican Adults / Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Victor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Parker, Erica (School of Paediatrics and Child Health, University of Western Australia) ; Fuente-Soro, Laura (Institut de Salut Global de Barcelona) ; Jairoce, Chenjerai (Centro de Investigação em Saúde da Manhiça (CISM)) ; Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ; Naniche, Denise (Centro de Investigação em Saúde da Manhiça (CISM)) ; Blanco, Julià (Universitat de Vic - Universitat Central de Catalunya)
During primary HIV infection (PHI), there is a striking cascade response of inflammatory cytokines and many cells of the immune system show altered frequencies and signs of extensive activation. These changes have been shown to have a relevant role in predicting disease progression; however, the challenges of identifying PHI have resulted in a lack of critical information about the dynamics of early pathogenic events. [...]
2018 - 10.3389/fimmu.2017.01925
Frontiers in immunology, Vol. 8 (january 2018) , art. 1925  
5.
12 p, 1.4 MB A Longitudinal Analysis Reveals Early Activation and Late Alterations in B Cells During Primary HIV Infection in Mozambican Adults / Jiménez, Montse (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez de la Concepción, María Luisa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Parker, Erica (Faculty of Health and Medical Sciences, University of Western Australia) ; Fuente-Soro, Laura (Centro de Investigação em Saúde da Manhiça (CISM)) ; Jairoce, Chenjerai (Centro de Investigação em Saúde da Manhiça (CISM)) ; Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Naniche, Denise (Centro de Investigação em Saúde da Manhiça (CISM)) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Primary HIV infection (PHI) and subsequent chronic infection alter B-cell compartment. However, longitudinal analysis defining the dynamics of B-cell alterations are still limited. We longitudinally studied B-cell subsets in individuals followed for 1 year after PHI (n = 40). [...]
2021 - 10.3389/fimmu.2020.614319
Frontiers in immunology, Vol. 11 (january 2021)  
6.
17 p, 6.0 MB Evolution of the gut microbiome following acute HIV-1 infection / Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pastor, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guillén, Yolanda (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Langhorst, Jost (University of Duisburg-Essen. Chair for Integrative Medicine and translationale Gastroenterology, Klinikum Bamberg) ; Parera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Calle, M. Luz (Universitat de Vic - Universitat Central de Catalunya) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Naniche, Denise (Centro de Investigação em Saúde da Manhiça (CISM)) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
In rhesus macaques, simian immunodeficiency virus infection is followed by expansion of enteric viruses but has a limited impact on the gut bacteriome. To understand the longitudinal effects of HIV-1 infection on the human gut microbiota, we prospectively followed 49 Mozambican subjects diagnosed with recent HIV-1 infection (RHI) and 54 HIV-1-negative controls for 9-18 months and compared them with 98 chronically HIV-1-infected subjects treated with antiretrovirals (n = 27) or not (n = 71). [...]
2019 - 10.1186/s40168-019-0687-5
Microbiome, Vol. 7 (may 2019)  
7.
15 p, 1.8 MB Different pattern of stool and plasma gastrointestinal damage biomarkers during primary and chronic HIV infection / Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Langhorst, Jost (Department of Internal and Integrative Medicine. Kliniken Essen-Mitte. Faculty of Medicine. University of Duisburg-Essen) ; Schröder, D. (Department of Internal and Integrative Medicine. Kliniken Essen-Mitte. Faculty of Medicine. University of Duisburg-Essen) ; Casellas, Aina (Barcelona Institute for Global Health (ISGlobal)) ; Ruffer, A. (Department of Internal and Integrative Medicine. Kliniken Essen-Mitte. Faculty of Medicine. University of Duisburg-Essen) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Massora, S. (Centro de Investigação em Saúde da Manhiça (CISM)) ; Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Naniche, D. (Centro de Investigação em Saúde da Manhiça (CISM)) ; Universitat Autònoma de Barcelona
Introduction Primary HIV infection (PHI) is the initial phase after HIV acquisition characterized by high viral replication, massive inflammatory response and irreversible immune-damage, particularly at the gastrointestinal level. [...]
2019 - 10.1371/journal.pone.0218000
PloS one, Vol. 14 Núm. 6 (june 2019) , p. e0218000  

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