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Articles, 2 records found

Articles	2 records found

17 p, 4.0 MB

Pharmacokinetics, biodistribution, and biosafety of PEGylated gold nanoparticles in vivo / Kozics, Katarina (Biomedical Research Center SAS (Bratislava, Eslovàquia). Department of Nanobiology) ; Sramkova, Monika (Biomedical Research Center SAS (Bratislava, Eslovàquia). Department of Nanobiology) ; Kopecka, Kristina (Biomedical Research Center SAS (Bratislava, Eslovàquia). Department of Nanobiology) ; Begerova, Patricia (Biomedical Research Center SAS (Bratislava, Eslovàquia). Department of Nanobiology) ; Manova, Alena (Slovak University of Technology in Bratislava. Institute of Analytical Chemistry) ; Krivosikova, Zora (Slovak Medical University in Bratislava. Department of Clinical and Experimental Pharmacotherapy) ; Sevcikova, Zuzana (University of Veterinary Medicine and Pharmacy in Kosice. Department of Morphological Disciplines) ; Liskova, Aurelia (Slovak Medical University in Bratislava. Laboratory of Immunotoxicology) ; Rollerová, Eva (Slovak Medical University in Bratislava. Laboratory of Toxicology) ; Dubaj, Tibor (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Wsolova, Ladislava (Slovak Medical University in Bratislava. Laboratory of Toxicology) ; Šimon, Peter (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics) ; Tulinska, Jana (Slovak Medical University in Bratislava. Laboratory of Immunotoxicology) ; Gabelova, Alena (Biomedical Research Center SAS. Department of Nanobiology)
Despite the obvious advantages of gold nanoparticles for biomedical applications, controversial and incomplete toxicological data hamper their widespread use. Here, we present the results from an in vivo toxicity study using gold nanoparticles coated with polyethylene glycol (PEG-AuNPs). [...]
2021 - DOI (Digital Object Identifier)

10.3390/nano11071702
Nanomaterials, Vol. 11, issue 7 (July 2021) , art. 1702

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12 p, 1.1 MB

Pharmacokinetics of PEGylated gold nanoparticles : in vitro-in vivo correlation / Dubaj, Tibor (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics) ; Kozics, Katarina (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ; Sramkova, Monika (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ; Manova, Alena (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ; Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ; Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ; Kohl, Yvonne (Fraunhofer Institute for Biomedical Engineering) ; Dusinska, Maria (Norwegian Institute for Air Research. Health Effects Laboratory) ; Rundén-Pran, Elise (Norwegian Institute for Air Research. Health Effects Laboratory) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Nelson, Andrew (University of Leeds. School of Chemistry) ; Gabelova, Alena (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ; Šimon, Peter (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics)
Data suitable for assembling a physiologically-based pharmacokinetic (PBPK) model for nanoparticles (NPs) remain relatively scarce. Therefore, there is a trend in extrapolating the results of in vitro and in silico studies to in vivo nanoparticle hazard and risk assessment. [...]
2022 - DOI (Digital Object Identifier)

10.3390/nano12030511
Nanomaterials, Vol. 12, issue 3 (Feb. 2022) , art. 511

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