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11 p, 680.8 KB |
Exposure to disinfection by-products in swimming pools and biomarkers of genotoxicity and respiratory damage - The PISCINA2 Study
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Font-Ribera, Laia (Institut de Salut Global de Barcelona) ;
Marco, Esther (Institut de Diagnòstic Ambiental i Estudis de l'Aigua (IDÆA-CSIC)) ;
Grimalt, Joan O. (Institut de Diagnòstic Ambiental i Estudis de l'Aigua (IDÆA-CSIC)) ;
Pastor Benito, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abramsson-Zetterberg, Lilianne (National Food Administration, Uppsala, Sweden) ;
Pedersen, Marie (University of Copenhagen) ;
Grummt, Tamara (German Environment Agency) ;
Junek, Ralf (German Environment Agency) ;
Barreiro, Esther (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Heederik, Dick (Institute for Risk Assessment Sciences (IRAS), Utrecht) ;
Spithoven, Jack (Institute for Risk Assessment Sciences (IRAS), Utrecht) ;
Critelli, Rossana (Italian Institute for Genomic Medicine (IIGM)) ;
Naccarati, Alessio (Italian Institute for Genomic Medicine (IIGM)) ;
Schmalz, Christina (University of Tübingen) ;
Zwiener, Christian (University of Tübingen) ;
Liu, Jiaqi (Hong Kong University of Science and Technology) ;
Zhang, Xiangru (Hong Kong University of Science and Technology) ;
Mitch, William (Stanford University) ;
Gracia-Lavedan, Esther (Universitat Pompeu Fabra) ;
Arjona, Lourdes (Universitat Pompeu Fabra) ;
de Bont, Jeroen (Institut de Salut Global de Barcelona) ;
Tarès, Lluïsa (Institut de Salut Global de Barcelona) ;
Vineis, Paolo (Imperial College London) ;
Kogevinas, M. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Villanueva, Cristina (Institut de Salut Global de Barcelona)
Background: Swimming in pools is a healthy activity that entails exposure to disinfection by-products (DBPs), some of which are irritant and genotoxic. Objectives: We evaluated exposure to DBPs during swimming in a chlorinated pool and the association with short-term changes in genotoxicity and lung epithelium permeability biomarkers. [...]
2019 -  10.1016/j.envint.2019.104988
Environment International, Vol. 131 (october 2019) , p. 104988
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7 p, 508.5 KB |
Novel genetic variants in differentiated thyroid cancer and assessment of the cumulative risk
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Figlioli, Gisella (University of Pisa. Department of Biology) ;
Chen, Bowang (German Cancer Research Center (DKFZ). Molecular Genetic Epidemiology (Germany)) ;
Elisei, Rossella (University of Pisa. Department of Endocrinology and Metabolism (Italy)) ;
Romei, Cristina (University of Pisa. Department of Endocrinology and Metabolism (Italy)) ;
Campo, Chiara (University of Pisa. Department of Biology (Italy)) ;
Cipollini, Monica (University of Pisa. Department of Biology (Italy)) ;
Cristaudo, Alfonso (University of Pisa. Department of Endocrinology and Metabolism (Italy)) ;
Bambi, Franco (Blood Centre, Azienda Ospedaliero Universitaria A. Meyer (Italy)) ;
Paolicchi, Elisa (University of Pisa. Department of Biology (Italy)) ;
Hoffmann, Per (University of Basel. Department of Biomedicine (Switzerland)) ;
Herms, Stefan (University of Basel. Department of Biomedicine (Switzerland)) ;
Kalemba, Michał (Maria Sklodowska-Curie Memorial Cancer Center. Department of Nuclear Medicine and Endocrine Oncology (Poland)) ;
Kula, Dorota (Maria Sklodowska-Curie Memorial Cancer Center. Department of Nuclear Medicine and Endocrine Oncology (Poland)) ;
Pastor Benito, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Velázquez Henar, Antonia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Jarząb, Barbara (Maria Sklodowska-Curie Memorial Cancer Center. Department of Nuclear Medicine and Endocrine Oncology (Poland)) ;
Landi, Stefano (University of Pisa. Department of Biology (Italy)) ;
Hemminki, Kari (Lund University. Center for Primary Health Care Research, Clinical Research Center (Sweden)) ;
Gemignani, Federica (University of Pisa. Department of Biology (Italy)) ;
Försti, Asta (Lund University. Center for Primary Health Care Research, Clinical Research Center (Sweden))
A genome-wide association study (GWAS) performed on a high-incidence Italian population followed by replications on low-incidence cohorts suggested a strong association of differentiated thyroid cancer (DTC) with single nucleotide polymorphisms (SNPs) at 9q22. [...]
2015 - 10.1038/srep08922
Scientific reports (Nature Publishing Group), Vol. 5 (March 2015) , art. 8922
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30 p, 6.3 MB |
High throughput toxicity screening and intracellular detection of nanomaterials
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Collins, Andrew R. (Universitetet i Oslo. Avdeling for ernæringsvitenskap) ;
Annangi, Balasubramanyam (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Rubio, Laura (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Dorn, Marco (Universität Leipzig. Institut für Medizinische Physik und Biphysik) ;
Merker, Carolin (Universität Leipzig. Institut für Medizinische Physik und Biphysik) ;
Estrela-Lopis, Irina (Universität Leipzig. Institut für Medizinische Physik und Biphysik) ;
Cimpan, Mihaela Roxana (Universitetet i Bergen. Det medisinske fakultet) ;
Ibrahim, Mohamed (Universitetet i Bergen. Det medisinske fakultet) ;
Cimpan, Emil (Høgskulen på Vestlandet) ;
Ostermann, Melanie (Universitetet i Bergen. Det medisinske fakultet) ;
Sauter, Alexander (Universitetet i Bergen. Det medisinske fakultet) ;
Yamani, Naouale El (Universitetet i Oslo. Avdeling for ernæringsvitenskap) ;
Shaposhnikov, Sergey (Universitetet i Oslo. Avdeling for ernæringsvitenskap) ;
Chevillard, Sylvie (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Paget, Vincent (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Grall, Romain (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Delic, Jozo (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Goñi-de-Cerio, Felipe (Gaiker, Centro Tecnológico) ;
Suarez-Merino, Blanca (Gaiker, Centro Tecnológico) ;
Fessard, Valérie (Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (France) ;
Hogeveen, Kevin N. (Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (France) ;
Fjellsbø, Lise Maria (Norsk institutt for luftforskning) ;
Pran, Elise Runden (Norsk institutt for luftforskning) ;
Brzicova, Tana (Ústav experimentální medicíny AV ČR, v. v. i.) ;
Topinka, Jan (Ústav experimentální medicíny AV ČR, v. v. i.) ;
Silva, Maria João (Instituto Nacional de Saúde Dr. Ricardo Jorge) ;
Leite, P. E. (Instituto Nacional de Metrologia, Calidad y Tecnología (Brasil)) ;
Ribeiro, A. R. (Instituto Nacional de Metrologia, Calidad y Tecnología (Brasil)) ;
Granjeiro, J. M. (Instituto Nacional de Metrologia, Calidad y Tecnología (Brasil)) ;
Grafström, Roland (Karolinska Institutet. Institute of Environmental Medicine) ;
Prina-Mello, Adriele (Trinity Centre for Health Sciences) ;
Dusinska, Maria (Norsk institutt for luftforskning)
With the growing numbers of nanomaterials (), there is a great demand for rapid and reliable ways of testing safety-preferably using in vitro approaches, to avoid the ethical dilemmas associated with animal research. [...]
2017 - 10.1002/wnan.1413
Wiley interdisciplinary reviews. Nanomedicine and Nanobiotechnology, Vol. 9, issue 1 (Jan./Feb. 2017) , e1413
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14 p, 1.1 MB |
NF-kB-mediated the expression of TBX15 in cancer cells
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Arribas Arranz, Jéssica ;
Cajuso, Tatiana ;
Rodio, Angela (Università Federico II. Dipartimento di Biologia e Patologia Cellulare e Molecolare) ;
Marcos Dauder, Ricardo (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Leonardi, Antonio (Università Federico II. Dipartimento di Biologia e Patologia Cellulare e Molecolare) ;
Velázquez Henar, Antonia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
TBX15 is a T-box transcription factor essential for development, also proposed as a marker in prostate cancer; and, recently, its antiapoptotic function indicates a role in carcinogenesis. Regulation of TBX15 is uncovered. [...]
2016 - 10.1371/journal.pone.0157761
PloS one, Vol. 11, Num. 6 (2016) , p. e0157761
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4 p, 256.5 KB |
Estima de l'heretabilitat d'alguns caràcters mètrics d'una població de Drosophila melanogaster del Prat de Llobregat
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Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Creus Capdevila, Amadeu (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Hem calculat l'heretabilitat de les microquetes interocel·lars,esternopleurals i abdominals, i de la longitud de la tíbia d'una soca de Drosophila melanogaster del Prat de Llobregat. El metode de calcul utilitzat és el de la regressió de la progenie sobre el progenitor. [...]
The heritability of interocellar, sternopleural and abdominal bristles, and tibia length, was estimated in a natural populations of Drosophila melanogaster from Prat de Llobregat (Barcelona) by the method of parent-offspring regression. [...]
1981
Estudi general, Núm. 2 (1981) , p. 197-200
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9 p, 421.4 KB |
An Epistatic Interaction between the PAX8 and STK17B Genes in Papillary Thyroid Cancer Susceptibility
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Landa, Iñigo (Centro Nacional de Investigaciones Oncológicas) ;
Boullosa, Cesar (Centro Nacional de Investigaciones Oncológicas) ;
Inglada Pérez, Lucia (Centro Nacional de Investigaciones Oncológicas) ;
Sastre Perona, Ana (Universidad Autónoma de Madrid. Instituto de Investigaciones Biomédicas "Alberto Sols") ;
Pastor Benito, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Velázquez, Antonia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Mancikova, Veronika (Centro Nacional de Investigaciones Oncológicas) ;
Ruiz Llorente, Sergio (Universidad Autónoma de Madrid. Instituto de Investigaciones Biomédicas "Alberto Sols") ;
Schiavi, Francesca (Institut d'Oncologia Vèneto. Clínica de Càncer Familiar i Oncoendocrinologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Malats i Riera, Núria (Centro Nacional de Investigaciones Oncológicas) ;
Opocher, Giuseppe (Veneto Institute of Oncology (Pàdua, Itàlia)) ;
Diaz Uriarte, Ramón (Universidad Autónoma de Madrid. Instituto de Investigaciones Biomédicas "Alberto Sols") ;
Santisteban, Pilar (Universidad Autónoma de Madrid. Instituto de Investigaciones Biomédicas "Alberto Sols") ;
Valencia, Alfonso (Centro Nacional de Investigaciones Oncológicas) ;
Robledo, Mercedes (Centro Nacional de Investigaciones Oncológicas)
Papillary Thyroid Cancer (PTC) is a heterogeneous and complex disease; susceptibility to PTC is influenced by the joint effects of multiple common, low-penetrance genes, although relatively few have been identified to date. [...]
2013 - 10.1371/journal.pone.0074765
PloS one, Vol. 8 Issue 9 (September 2013) , p. e74765
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Possible role of WDR3 gene on genome stability in thyroid cancer patients
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García Quispes, Wilser Andrés (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Pastor Benito, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Galofré, Pere (Hospital Universitari Vall d'Hebron) ;
Biarnés, Josefina (Hospital Universitari de Girona Doctor Josep Trueta) ;
Castell Conesa, Joan (Hospital Universitari Vall d'Hebron) ;
Velázquez Henar, Antonia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The role of the WDR3 gene on genomic instability has been evaluated in a group of 115 differentiated thyroid cancer (DTC) patients. Genomic instability has been measured according to the response of peripheral blood lymphocytes to ionizing radiation (0. [...]
2012 - 10.1371/journal.pone.0044288
PloS one, Vol. 7, Issue 9 (September 2012) , p. e44288
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