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10 p, 893.6 KB Efferocytosis Promotes Suppressive Effects on Dendritic Cells through Prostaglandin E2 Production in the Context of Autoimmunity / Pujol Autonell, Irma (Hospital Germans Trias i Pujol) ; Ampudia, Rosa Maria (Hospital Germans Trias i Pujol) ; Planas, Raquel (Hospital Germans Trias i Pujol) ; Marin-Gallen, Silvia (Hospital Germans Trias i Pujol) ; Carrascal, Jorge (Universitat de Lleida. Departament de Ciències Bàsiques) ; Sanchez, Alex (Vall d'Hebron Hospitals. Institut de Recerca) ; Marin, Ana (Hospital Germans Trias i Pujol) ; Puig Domingo, Manuel (Institut de Recerca "Germans Trias i Pujol". Secció Endocrinologia i Nutrició) ; Pujol-Borrell, Ricardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Verdaguer, Joan (Universitat de Lleida. Departament de Ciències Bàsiques) ; Vives Pi, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Introduction: Efferocytosis is a crucial process by which apoptotic cells are cleared by phagocytes, maintaining immune tolerance to self in the absence of inflammation. Peripheral tolerance, lost in autoimmune processes, may be restored by the administration of autologous dendritic cells loaded with islet apoptotic cells in experimental type 1 diabetes. [...]
2013 - 10.1371/journal.pone.0063296
PLoS One, Vol. 8 Issue 5 (May 2013) , p. e63296  

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