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Artículos, Encontrados 2 registros

Artículos	Encontrados 2 registros

21 p, 2.2 MB

Hepato(Geno)toxicity assessment of nanoparticles in a HepG2 liver spheroid model / Elje, Elisabeth (Norwegian Institute for Air Research. Department for Environmental Chemistry) ; Mariussen, Espen (Norwegian Institute for Air Research. Department for Environmental Chemistry) ; Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ; Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Kohl, Yvonne (Fraunhofer Institute for Biomedical Engineering IBMT) ; Dusinska, Maria (Norwegian Institute for Air Research. Department for Environmental Chemistry)) ; Rundén-Pran, Elise (Norwegian Institute for Air Research. Department for Environmental Chemistry)
(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures better than 2D cultures. [...]
2020 - DOI (Digital Object Identifier)

10.3390/nano10030545
Nanomaterials, Vol. 10, issue 3 (March 2020) , art. E545

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15 p, 4.6 MB

Microfluidic in vitro platform for (nano)safety and (nano)drug efficiency screening / Kohl, Yvonne (Fraunhofer Institute for Biomedical Engineering) ; Biehl, Margit (Fraunhofer Institute for Biomedical Engineering) ; Spring, Sarah (Fraunhofer Institute for Biomedical Engineering) ; Hesler, Michelle (Fraunhofer Institute for Biomedical Engineering) ; Ogourtsov, Vladimir (University College Cork. Tyndall National Institute) ; Todorovic, Miomir (University College Cork. Tyndall National Institute) ; Owen, Joshua (University of Leeds. Institute of Thermofluids) ; Elje, Elisabeth (University of Oslo. Department of Molecular Medicine) ; Kopecka, Kristina (Slovak Academy of Sciences. Biomedical Research Center) ; Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ; Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ; Šimon, Peter (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics) ; Dubaj, Tibor (Institute of Physical Chemistry and Chemical Physicsof SUT) ; Rundén-Pran, Elise (Norwegian Institute for Air Research. Department for Environmental Chemistry) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; William, Nicola (University of Leeds. School of Chemistry) ; von Briesen, Hagen (Fraunhofer Institute for Biomedical Engineering) ; Wagner, Sylvia (Fraunhofer Institute for Biomedical Engineering) ; Kapur, Nikil (University of Leeds. Institute of Thermofluids) ; Mariussen, Espen (Norwegian Institute for Air Research. Department for Environmental Chemistry) ; Nelson, Andrew (University of Leeds. School of Chemistry) ; Gabelova, Alena (Slovak Academy of Sciences. Biomedical Research Center) ; Dusinska, Maria (Norwegian Institute for Air Research. Department for Environmental Chemistry) ; Velten, Thomas (Fraunhofer Institute for Biomedical Engineering) ; Knoll, Thorsten (Fraunhofer Institute for Biomedical Engineering)
Microfluidic technology is a valuable tool for realizing more in vitro models capturing cellular and organ level responses for rapid and animal-free risk assessment of new chemicals and drugs. Microfluidic cell-based devices allow high-throughput screening and flexible automation while lowering costs and reagent consumption due to their miniaturization. [...]
2021 - DOI (Digital Object Identifier)

10.1002/smll.202006012
Small, Vol. 17, issue 15 (April 2021) , art. 2006012

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