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1.
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12 p, 3.8 MB |
Comparison of the pathological outcome and disease progression of two Mycobacterium caprae experimental challenge models in goats : endobronchial inoculation vs. intranasal nebulization
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Melgarejo, Cristian (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Cobos Arnalot, Àlex (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Planas Padrós, Carles (Universitat Autònoma de Barcelona. Fundació Hospital Clínic Veterinari) ;
Fondevila, Jaume (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Martín, Maite (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Cervera, Zoraida (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Moll Sánchez, Xavier (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Espada, Yvonne (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Domingo, Mariano (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Vidal Barba, Enric (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Pérez de Val, Bernat (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Goats are natural hosts of tuberculosis (TB) and are a valid animal model to test new vaccines and treatments to control this disease. In this study, a new experimental model of TB in goats based on the intranasal nebulization of Mycobacterium caprae was assessed in comparison with the endobronchial route of infection. [...]
2023 -  10.3389/fmicb.2023.1236834
Frontiers in microbiology, Vol. 14 (august 2023)
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2.
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12 p, 1.3 MB |
Long-term efficacy of BCG vaccination in goat herds with a high prevalence of tuberculosis
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Arrieta-Villegas, Claudia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Allepuz Palau, Alberto (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Grasa, Miriam (Agrupació de Defensa Sanitària de Cabrum i Oví Lleter de Catalunya) ;
Martín, Maite (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Cervera, Zoraida (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Mercader, Irene (Generalitat de Catalunya. Departament d'Agricultura, Ramaderia, Pesca i Alimentació (DARP)) ;
López-Soria, Sergio (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Domingo, Mariano (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Pérez de Val, Bernat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Vaccination of goats against tuberculosis (TB) has been promoted as an ancillary tool for controlling the disease in infected livestock herds. A three-year trial to assess the efficacy of BCG vaccine was carried out in five goat herds. [...]
2020 - 10.1038/s41598-020-77334-1
Scientific reports, Vol. 10 (november 2020)
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3.
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11 p, 2.1 MB |
Phylogenetic relationships investigation of Mycobacterium caprae strains from sympatric wild boar and goats based on whole genome sequencing
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Ciaravino, Giovanna (Universitat Autònoma de Barcelona) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Cortey, Martí (Universitat Autònoma de Barcelona) ;
Martín, Maite (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Sanz, Albert (Generalitat de Catalunya. Departament d'Agricultura, Ramaderia, Pesca i Alimentació (DARP)) ;
Mercader, Irene (Generalitat de Catalunya. Departament d'Agricultura, Ramaderia, Pesca i Alimentació (DARP)) ;
Perea, Claudia (United States Department of Agriculture) ;
Robbe-Austerman, Suelee (United States Department of Agriculture) ;
Allepuz Palau, Alberto (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pérez de Val, Bernat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Tuberculosis (TB) in wildlife challenges epidemiological surveillance and disease control. An outbreak of TB was detected in a free-ranging wild boar population of a Natural Park in Catalonia (Spain) and the outbreak investigation was conducted in the area. [...]
2020 - 10.1111/tbed.13816
Transboundary and Emerging Diseases, Vol. 68 (september 2020) , p. 1476-1486
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4.
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16 p, 20.5 MB |
Immunogenicity and Protection against Mycobacterium caprae Challenge in Goats Vaccinated with BCG and Revaccinated after One Year
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Arrieta-Villegas, Claudia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Martin, Maite (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Verdés Martinez, Judit (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Moll Sánchez, Xavier (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Espada, Yvonne (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Singh, Mahavir (LIONEX Diagnostics and Therapeutics GmbH) ;
Villarreal Ramos, Bernardo (Animal Health and Veterinary Laboratories Agency. TB Research Group) ;
Domingo, Mariano (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Pérez de Val, Bernat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Vaccination has been proposed as a supplementary tool for the control of tuberculosis in livestock. The long-term immunogenicity elicited by bacillus Calmette-Guerin (BCG) and the efficacy of revaccination were investigated in thirty goat kids distributed into three groups: unvaccinated controls, BCG (vaccinated at week 0) and BCG-BCG (vaccinated at weeks 0 and 56). [...]
2020 - 10.3390/vaccines8040751
Vaccines (Basel), Vol. 8 Núm. 4 (2020) , p. 751
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5.
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27 p, 2.2 MB |
Novel polyomaviruses in mammals from multiple orders and reassessment of polyomavirus evolution and taxonomy
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Ehlers, Bernhard (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Anoh, A. E. (Université Alassane Ouattara. Centre de Recherche pour le Développement) ;
Salem, N. B. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Broll, S. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Couacy-Hymann, E. (Laboratoire National d'Appui Au Développement Agricole. Laboratoire Central de Pathologie Animale) ;
Fischer, D. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Gedvilaite, A. (Institute of Biotechnology. Vilnius University) ;
Ingenhütt, N. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Liebmann, S. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Martin, Maite (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Mossoun, A. (Laboratoire National d'Appui Au Développement Agricole. Laboratoire Central de Pathologie Animale) ;
Mugisha, L. (Makerere University. College of Veterinary Medicine. Animal Resources and Biosecurity (COVAB)) ;
Muyembe-Tamfum, J. J. (Institut National de Recherche Bio-Médicale) ;
Pauly, M. (Robert Koch Institute. Epidemiology of Highly Pathogenic Microorganisms) ;
De Val, B. P. (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Preugschas, H. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Richter, D. (Technische Universität Braunschweig) ;
Schubert, G. (Robert Koch Institute. Epidemiology of Highly Pathogenic Microorganisms) ;
Szentiks, C. A. (Leibniz Institute for Zoo and Wildlife Research (IZW)) ;
Teichmann, T. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Walter, C. (Robert Koch Institute. Division 12 Measles, Mumps, Rubella and Viruses Affecting Immunocompromised Patients) ;
Ulrich, R. G. (Partner Site Hamburg-Lübeck-Borstel-Insel Riems. German Center for Infection Research (DZIF)) ;
Wiersma, L. (Robert Koch Institute. Epidemiology of Highly Pathogenic Microorganisms) ;
Leendertz, F. H. (Robert Koch Institute. Epidemiology of Highly Pathogenic Microorganisms) ;
Calvignac-Spencer, S. (Robert Koch Institute. Viral Evolution)
As the phylogenetic organization of mammalian polyomaviruses is complex and currently incompletely resolved, we aimed at a deeper insight into their evolution by identifying polyomaviruses in host orders and families that have either rarely or not been studied. [...]
2019 - 10.3390/v11100930
Viruses, Vol. 11 Núm. 10 (october 2019) , p. 930
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6.
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2 p, 138.8 KB |
Genome Sequence of Bovine Polyomavirus 1 Detected in a Salers Cow (Bos taurus) from Catalonia, Spain
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Ben Salem, Nicole ;
Pérez de Val, Bernat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Martin, Maite (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Moens, Ugo ;
Ehlers, Bernhard
We identified a variant of the first bovine polyomavirus (BPyV1; family Polyomaviridae) in a lymph node of a Salers cow. As the 2 previously published genome sequences of this virus originated from fetal bovine serum and ground beef, respectively, this is the first BPyV1 genome that could be traced back to an individual.
2016 - 10.1128/genomeA.01658-15
Genome announcements, Vol. 4 (january 2016)
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7.
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12 p, 2.0 MB |
A Multi-Antigenic Adenoviral-Vectored Vaccine Improves BCG-Induced Protection of Goats against Pulmonary Tuberculosis Infection and Prevents Disease Progression
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Pérez de Val, Bernat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Moll Sánchez, Xavier (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Villarreal Ramos, Bernardo (Animal Health and Veterinary Laboratories Agency. TB Research Group (Addlestone, Regne Unit)) ;
Gilbert, Sarah C. (University of Oxford. The Jenner Institute) ;
Andaluz Martínez, Anna (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Martín, Maite (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Nofrarías Espadamala, Miquel (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
McShane, Helen (University of Oxford. The Jenner Institute) ;
Vordermeier, H. Martin (Animal Health and Veterinary Laboratories Agency. TB Research Group (Addlestone, Regne Unit)) ;
Domingo, Mariano (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
The "One world, one health" initiative emphasizes the need for new strategies to control human and animal tuberculosis (TB) based on their shared interface. A good example would be the development of novel universal vaccines against Mycobacterium tuberculosis complex (MTBC) infection. [...]
2013 - 10.1371/journal.pone.0081317
PloS one, Vol. 8 Issue 11 (November 2013) , p. e81317
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8.
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11 p, 559.3 KB |
Effects of vaccination against paratuberculosis on tuberculosis in goats : diagnostic interferences and cross-protection
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Pérez de Val, Bernat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Nofrarías Espadamala, Miquel (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
López-Soria, Sergio (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Garrido, Joseba M. ;
Vordermeier, H. Martin ;
Villarreal Ramos, Bernardo ;
Martín, Maite (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Puentes, Eugenia ;
Juste, Ramón A. ;
Domingo, Mariano (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Background: Most countries carrying out campaigns of bovine tuberculosis (TB) eradication impose a ban on the use of mycobacterial vaccines in cattle. However, vaccination against paratuberculosis (PTB) in goats is often allowed even when its effect on TB diagnosis has not been fully evaluated. [...]
Results: Evaluation of interferon-γ (IFN-γ) secretion induced by avian and bovine tuberculins (PPD) showed a predominant avian PPD-biased response in the vaccinated group from week 4 post-vaccination onward. [...]
2012 - 10.1186/1746-6148-8-191
BMC veterinary research, Vol. 8, N. 191 (October 2012) , p. 1-11
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