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11 p, 575.8 KB |
Global Emergence of Resistance to Fluconazole and Voriconazole in Candida parapsilosis in Tertiary Hospitals in Spain During the OVID-19 Pandemic
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Trevijano-Contador, Nuria (Instituto de Salud Carlos III) ;
Torres-Cano, Alba (Instituto de Salud Carlos III) ;
Carballo-González, Cristina (Instituto de Salud Carlos III) ;
Puig-Asensio, Mireia (Hospital Universitari de Bellvitge) ;
Martin-Gomez, M. Teresa (Hospital Universitari Vall d'Hebron) ;
Jiménez-Martínez, Emilio (Hospital Universitari Vall d'Hebron) ;
Romero, Daniel (Hospital Universitari Vall d'Hebron) ;
Nuvials, Xavier (Hospital Universitari Vall d'Hebron) ;
Olmos-Arenas, Roberto (Hospital Universitari de Bellvitge) ;
Moretó-Castellsagué, María Clara (Hospital Universitari de Bellvitge) ;
Fernández-Delgado, Lucía (Hospital Universitari de Bellvitge) ;
Rodríguez-Sevilla, Graciela (Hospital Universitari de Bellvitge) ;
Aguilar-Sánchez, María-Mercedes (Hospital Universitari de Bellvitge) ;
Ayats-Ardite, Josefina (Hospital Universitari de Bellvitge) ;
Ardanuy, Carmen (Hospital Universitari de Bellvitge) ;
Sanchez-Romero, Isabel (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Muñoz-Algarra, María (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Merino-Amador, Paloma (Hospital Universitario Clínico San Carlos (Madrid)) ;
González-Romo, Fernando (Hospital Universitario Clínico San Carlos (Madrid)) ;
Megías-Lobón, Gregoria (Hospital Universitario de Burgos) ;
García-Campos, Jose Angel (Hospital Universitario de Burgos) ;
Mantecón-Vallejo, María Ángeles (Hospital Universitario de Burgos) ;
Alcoceba, Eva (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Escribano Martos, Pilar (Hospital General Universitario Gregorio Marañón) ;
Guinea, Jesús (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Durán-Valle, Maria Teresa (Hospital Universitario de Móstoles (Madrid)) ;
Fraile-Torres, Arturo (Hospital Universitario de Móstoles (Madrid)) ;
Roiz-Mesones, María Pía (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Lara-Plaza, Isabel (Hopsital Universitario de Móstoles) ;
de Ayala, Ana Pérez (Hospital Universitario 12 de Octubre (Madrid)) ;
Simón-Sacristán, María (Hospital Central de la Defensa Gómez Ulla) ;
Collazos-Blanco, Ana (Hospital Central de la Defensa Gómez Ulla) ;
Nebreda-Mayoral, Teresa (Hospital Clínico Universitario de Valladolid) ;
March-Roselló, Gabriel (Hospital Clínico Universitario de Valladolid) ;
Alcázar-Fuoli, Laura ;
Zaragoza, Óscar (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona
Candida parapsilosis is a frequent cause of candidemia worldwide. Its incidence is associated with the use of medical implants, such as central venous catheters or parenteral nutrition. This species has reduced susceptibility to echinocandins, and it is susceptible to polyenes and azoles. [...]
2022 -  10.1093/ofid/ofac605
Open Forum Infectious Diseases, Vol. 9 (november 2022)
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0 p, 1.1 MB |
Community-acquired pneumonia in hospitalised patients : changes in aetiology, clinical presentation, and severity outcomes in a 10-year period
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Sellarès-Nadal, Júlia (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Burgos, Joaquín (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Martin-Gomez, M. Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Antón, Andrés (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sordé, Roger (Hospital de Trauma Manuel Giagni (Uruguay)) ;
Bosch-Nicolau, Pau (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Falcó-Roget, Anna (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Kirkegaard, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez-Pardo, Dolors (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Len, Oscar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Falcó, Vicenç (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Community-acquired pneumonia (CAP) is a frequent cause of hospitalisation. Several factors, such as pandemics, vaccines and globalisation may lead to changes in epidemiology, clinical presentation, and outcomes of CAP, which oblige to a constant actualisation. [...]
2022 - 10.1080/07853890.2022.2138529
Annals of Medicine, Vol. 54 (november 2022) , p. 3052-3059
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12 p, 1.0 MB |
An Immunochemical Approach to Detect the Quorum Sensing-Regulated Virulence Factor 2-Heptyl-4-Quinoline N-Oxide (HQNO) Produced by Clinical Isolates
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Montagut, Enrique J. (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Raya, Juan (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Martin-Gomez, M. Teresa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Vilaplana, Lluïsa (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Rodriguez-Urretavizcaya, Barbara (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Marco, María Pilar (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina)
Understanding quorum sensing (QS) and its role in the development of pathogenesis may provide new avenues for diagnosing, surveillance, and treatment of infectious diseases. For this purpose, the availability of reliable and efficient analytical diagnostic tools suitable to specifically detect and quantify these essential QS small molecules and QS regulated virulence factors is crucial. [...]
2022 - 10.1128/spectrum.01073-21
Microbiology Spectrum, Vol. 10, Num. 4 (July 2022) , art. e01073-21
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10 p, 505.0 KB |
Safety and Effectiveness of Isavuconazole Treatment for Fungal Infections in Solid Organ Transplant Recipients (ISASOT Study)
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Monforte, Arnau (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Los-Arcos, Ibai (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Martín-Gómez, Maria Teresa (Hospital Universitari Vall d'Hebron) ;
Campany-Herrero, David (Hospital Universitari Vall d'Hebron) ;
Sacanell, Judith (Hospital Universitari Vall d'Hebron) ;
Berastegui García, Cristina (Hospital Universitari Vall d'Hebron) ;
Márquez-Algaba, Ester (Hospital Universitari Vall d'Hebron) ;
Sempere, Abiu (Hospital Universitari Vall d'Hebron) ;
Nuvials, Xavier (Hospital Universitari Vall d'Hebron) ;
Deu, Maria (Hospital Universitari Vall d'Hebron) ;
Castells, Lluís (Hospital Universitari Vall d'Hebron) ;
Moreso, Francesc (Hospital Universitari Vall d'Hebron) ;
Bravo Masgoret, Carles (Hospital Universitari Vall d'Hebron) ;
Gavaldà, Joan (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Len, Oscar (Universitat Autònoma de Barcelona. Departament de Medicina)
Isavuconazole (ISA) is an alternative treatment for spp. and other fungal infections, but evidence regarding its use in solid organ transplant recipients (SOTR) is scarce. All SOTR who received ISA for treatment of a fungal infection (FI) at our center from December 2017 to January 2021 were included. [...]
2022 - 10.1128/spectrum.01784-21
Microbiology Spectrum, Vol. 10 Núm. 1 (february 2022)
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17 p, 555.8 KB |
Voriconazole Use in Children : Therapeutic Drug Monitoring and Control of Inflammation as Key Points for Optimal Treatment
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Valle-T-Figueras, José María (Institut d'Investigació Biomèdica Sant Pau) ;
Renedo-Miró, Berta (Hospital Universitari Vall d'Hebron) ;
Benítez Carabante, Maria Isabel (Hospital Universitari Vall d'Hebron) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron) ;
Vima Bofarull, Jaume (Hospital Universitari Vall d'Hebron) ;
Mendoza-Palomar, Natalia Ana (Hospital Universitari Vall d'Hebron) ;
Martin-Gomez, M. Teresa (Hospital Universitari Vall d'Hebron) ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Voriconazole plasma concentrations (PC) are highly variable, particularly in children. Dose recommendations in 2-12-year-old patients changed in 2012. Little data on therapeutic drug monitoring (TDM) after these new recommendations are available. [...]
2021 - 10.3390/jof7060456
Journal of Fungi, Vol. 7 (june 2021)
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20 p, 2.3 MB |
Consensus Multilocus Sequence Typing Scheme for Pneumocystis jirovecii
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Pasic, Lana (Westmead Institute for Medical Research) ;
Goterris, Lidia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Guerrero Murillo, Mercedes (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Irinyi, Laszlo (Westmead Institute for Medical Research) ;
Kan, Alex (Westmead Institute for Medical Research) ;
Ponce, Carolina A. (Instituto de Ciencias Biomédicas) ;
Vargas, Sergio L. (Instituto de Ciencias Biomédicas) ;
Martin-Gomez, M. Teresa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Meyer, Wieland (Westmead Hospital)
Pneumocystis jirovecii is an opportunistic human pathogenic fungus causing severe pneumonia mainly in immunocompromised hosts. Multilocus sequence typing (MLST) remains the gold standard for genotyping of this unculturable fungus. [...]
2020 - 10.3390/jof6040259
Journal of Fungi, Vol. 6, Num. 4 (October 2020) , art. 259
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10 p, 2.5 MB |
Population dynamics and antigenic drift of Bordetella pertussis following whole cell vaccine replacement, Barcelona, Spain, 1986-2015
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Mir-Cros, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Moreno-Mingorance, Albert (Hospital Universitari Vall d'Hebron) ;
Martin-Gomez, M. Teresa (Departament de Genètica i de Microbiologia) ;
Codina, María Gema (Hospital Universitari Vall d'Hebron) ;
Cornejo-Sánchez, Thais (Hospital Universitari Vall d'Hebron) ;
Rajadell Guiu, Mireia (Departament de Genètica i de Microbiologia) ;
Van Esso, Diego (Institut Català de la Salut) ;
Rodrigo Gonzalo de Líria, Carlos (Hospital Universitari Vall d'Hebron) ;
Campins Martí, Magda (Hospital Universitari Vall d'Hebron) ;
Jané i Checa, Mireia (Servei Català de la Salut) ;
Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ;
Fàbrega-Santamaria, Anna (Universitat de Vic - Universitat Central de Catalunya) ;
González-López, Juanjo 1975- (Departament de Genètica i de Microbiologia) ;
Hospital Universitari Vall d'Hebron
Among the factors associated with the resurgence of whooping cough, special emphasis has been given to pathogen adaptation after the introduction of the acellular vaccine (ACV). To assess the impact of the vaccine transition strategy from whole-cell vaccine (WCV) to ACV on population dynamics of Bordetella pertussis in Barcelona (Spain), we studied 339 isolates collected from 1986 to 2015 by PFGE and multi-locus variable-number tandem repeat analysis (MLVA). [...]
2019 - 10.1080/22221751.2019.1694395
Emerging microbes & infections, Vol. 8 (november 2019) , p. 1711-1720
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