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12 p, 7.2 MB Reduction of intratumoral brain perfusion by noninvasive transcranial electrical stimulation / Sprugnoli, G. (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ; Monti, L. (Unit of Neuroimaging and Neurointervention. "Santa Maria Alle Scotte" Medical Center) ; Lippa, L. (Unit of Neurosurgery. "Santa Maria Alle Scotte" Medical Center) ; Neri, F. (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ; Mencarelli, L. (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ; Ruffini, G. (Neuroelectrics) ; Salvador, R. (Neuroelectrics) ; Oliveri, G. (Unit of Neurosurgery. "Santa Maria Alle Scotte" Medical Center) ; Batani, B. (Unit of Neurosurgery. "Santa Maria Alle Scotte" Medical Center) ; Momi, Davide (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ; Cerase, A. (Unit of Neuroimaging and Neurointervention. "Santa Maria Alle Scotte" Medical Center) ; Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ; Rossi, A. (Department of Medicine. Surgery and Neuroscience. Human Physiology Section. Siena Medical School) ; Rossi, S. (Department of Medicine. Surgery and Neuroscience. Human Physiology Section. Siena Medical School) ; Santarnecchi, E. (Berenson-Allen Center for Noninvasive Brain Stimulation. Beth Israel Medical Center. Harvard Medical School) ; Universitat Autònoma de Barcelona
Malignant brain neoplasms have a poor prognosis despite aggressive treatments. Animal models and evidence from human bodily tumors reveal that sustained reduction in tumor perfusion via electrical stimulation promotes tumor necrosis, therefore possibly representing a therapeutic option for patients with brain tumors. [...]
2019 - 10.1126/sciadv.aau9309
Science advances, Vol. 5 Núm. 8 (14 2019) , p. eaau9309  
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