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1.
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8 p, 1.4 MB |
Clinical effectiveness of routine first-trimester combined screening for pre-eclampsia in Spain with the addition of placental growth factor
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Garcia-Manau, Pablo (Hospital Universitari Vall d'Hebron) ;
Bonacina, Erika (Hospital Universitari Vall d'Hebron) ;
Serrano, Berta (Hospital Universitari Vall d'Hebron) ;
Caamiña Álvarez, Sara (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Ricart, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lopez-Quesada, Eva (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Vives, Àngels (Consorci Sanitari de Terrassa) ;
Lopez, Monica (Hospital Universitari Joan XXIII de Tarragona) ;
Pintado, Elena (Hospital Universitario de Getafe (Madrid)) ;
Maroto, Anna (Hospital Universitari de Girona Doctor Josep Trueta) ;
Catalan, Sara (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Cullell-Dalmau, Marta (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
del Barco, Ester (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Hernandez, Alina (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Miserachs, Marta (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
San Jose, Marta (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Armengol-Alsina, Mireia (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Carreras Moratonas, Elena (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron)
Pre-eclampsia affects 2%-8% of pregnancies and is one of the leading causes of maternal and perinatal morbidity and mortality. First-trimester screening using an algorithm that combines maternal characteristics, mean arterial blood pressure, uterine artery pulsatility index and biomarkers (pregnancy-associated plasma protein-A and placental growth factor) is the method that achieves a greater diagnostic accuracy. [...]
2023 -  10.1111/aogs.14687
Acta Obstetricia et Gynecologica Scandinavica, Vol. 102 (october 2023) , p. 1711-1718
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2.
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9 p, 3.8 MB |
Mid-trimester uterine artery Doppler for aspirin discontinuation in pregnancies at high risk for preterm pre-eclampsia : Post-hoc analysis of StopPRE trial
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Bonacina, Erika (Hospital Universitari Vall d'Hebron) ;
Garcia-Manau, Pablo (Hospital Universitari Vall d'Hebron) ;
López, Mónica (Hospital Universitari Joan XXIII de Tarragona) ;
Caamiña Álvarez, Sara (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Vives, Àngels (Department of Obstetrics. Consorci Sanitari de Terrassa) ;
Lopez-Quesada, Eva (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Ricart, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Maroto, Anna (Hospital Universitari de Girona Doctor Josep Trueta) ;
de Mingo, Laura (Hospital Universitario Severo Ochoa, Leganés) ;
Pintado, Elena (Hospital Universitario de Getafe (Madrid)) ;
Castillo-Ribelles, Laura (Hospital Universitari Vall d'Hebron) ;
Martín, Lourdes (Hospital Universitari Joan XXIII de Tarragona) ;
Rodriguez-Zurita, Alicia (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Garcia, Esperanza (Consorci Sanitari de Terrassa) ;
Pallarols, Mar (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Vidal-Sagnier, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teixidor, Mireia (Hospital Universitari de Girona Doctor Josep Trueta) ;
Orizales-Lago, Carmen (Hospital Universitario Severo Ochoa, Leganés) ;
Pérez-Gomez, Adela (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Ocaña, Vanesa (Hospital Universitario de Getafe (Madrid)) ;
Puerto, Lidia (Hospital Universitari Joan XXIII de Tarragona) ;
Millán, Pilar (Consorci Sanitari de Terrassa) ;
Alsius, Mercè (Hospital Universitari de Girona Doctor Josep Trueta) ;
Díaz Rodríguez, Sonia (Hospital Universitario de Getafe (Madrid)) ;
Maiz, Nerea (Hospital Universitari Vall d'Hebron) ;
Carreras Moratonas, Elena (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Suy, A. (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Mendoza, Manel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)
Objective: To assess whether aspirin treatment can be discontinued in pregnancies with normal uterine artery pulsatility index (≤90th percentile) at 24-28 weeks. Design: Post-hoc analysis of a clinical trial. [...]
2023 - 10.1111/1471-0528.17631
BJOG, Vol.131 (2023)
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3.
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6 p, 662.0 KB |
Shared risk factors for -19 and preeclampsia in the first trimester : An observational study
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Serrano, Berta (Hospital Universitari Vall d'Hebron) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron) ;
Garcia-Aguilar, Paula (Hospital Universitari Vall d'Hebron) ;
Bonacina, Erika (Hospital Universitari Vall d'Hebron) ;
Garcia-Ruiz, Itziar (Hospital Universitari Vall d'Hebron) ;
Garcia-Manau, Pablo (Hospital Universitari Vall d'Hebron) ;
Gil, Judit (Hospital Universitari Vall d'Hebron) ;
Armengol-Alsina, Mireia (Hospital Universitari Vall d'Hebron) ;
Fernández-Hidalgo, Nuria (Hospital Universitari Vall d'Hebron) ;
Sulleiro Igual, Elena (Hospital Universitari Vall d'Hebron) ;
Lopez Martinez, Rosa (Hospital Universitari Vall d'Hebron) ;
Ricart, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martin, Lourdes (Hospital Universitari Joan XXIII de Tarragona) ;
Lopez-Quesada, Eva (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Vives, Angels (Universitat Internacional de Catalunya) ;
Maroto, Anna (Hospital Universitari de Girona Doctor Josep Trueta) ;
Maiz, Nerea (Hospital Universitari Vall d'Hebron) ;
Suy, Anna (Hospital Universitari Vall d'Hebron) ;
Carreras Moratonas, Elena (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
The association between preeclampsia and coronavirus disease 2019 (COVID-19) is under study. Previous publications have hypothesized the existence of shared risk factors for both conditions or a deficient trophoblastic invasion as possible explanations for this association. [...]
2022 - 10.1111/aogs.14371
Acta Obstetricia et Gynecologica Scandinavica, Vol. 101 (may 2022) , p. 803-808
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4.
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10 p, 364.8 KB |
Confirmation of preeclampsia-like syndrome induced by severe COVID-19 : An Observational Study
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Serrano, Berta (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Bonacina, Erika (Hospital Universitari Vall d'Hebron) ;
Garcia-Ruiz, Itziar (Hospital Universitari Vall d'Hebron) ;
Mendoza, Manel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Garcia-Manau, Pablo (Hospital Universitari Vall d'Hebron) ;
Garcia-Aguilar, Paula (Hospital Universitari Vall d'Hebron) ;
Gil, Judit (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Armengol-Alsina, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fernández-Hidalgo, Nuria (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Sulleiro Igual, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Castillo-Ribelles, Laura (Hospital Universitari Vall d'Hebron) ;
Maiz, Nerea (Hospital Universitari Vall d'Hebron) ;
Carreras Moratonas, Elena (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Suy, Anna (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)
Since the outbreak of the COVID-19 pandemic, some studies have reported an increased preeclampsia (PE) incidence in pregnant women with SARS-CoV-2 infection. Several explanations for this association have been proposed, including a preeclampsia-like syndrome induced by severe COVID-19. [...]
2022 - 10.1016/j.ajogmf.2022.100760
American journal of obstetrics & gynecology, maternal-fetal medicine, october 2022
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5.
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8 p, 1.1 MB |
Angiogenic factors for planning fetal surveillance in fetal growth restriction and small-for-gestational-age fetuses : A prospective observational study
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Bonacina, Erika (Hospital Universitari Vall d'Hebron) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron) ;
Farràs Llobet, Alba (Hospital Universitari Vall d'Hebron) ;
Garcia-Manau, Pablo (Hospital Universitari Vall d'Hebron) ;
Serrano, Berta (Hospital Universitari Vall d'Hebron) ;
Hurtado, Ivan (Hospital Universitari Vall d'Hebron) ;
Ferrer-Oliveras, Raquel (Hospital Universitari Vall d'Hebron) ;
Illan, Lidia (Hospital Universitari Vall d'Hebron) ;
Armengol-Alsina, Mireia (Hospital Universitari Vall d'Hebron) ;
Carreras Moratonas, Elena (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
The aim of this study was to assess the added value of the soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) ratio for adjusting the periodicity of ultrasound examinations in early-onset fetal growth restriction (FGR) and small for gestational age (SGA). [...]
2022 - 10.1111/1471-0528.17151
BJOG, Vol. 129 (april 2022) , p. 1870-1877
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6.
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11 p, 1.1 MB |
First-trimester screening for pre-eclampsia and small for gestational age : A comparison of the gaussian and Fetal Medicine Foundation algorithms
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Serrano, Berta (Hospital Universitari Vall d'Hebron) ;
Bonacina, Erika (Hospital Universitari Vall d'Hebron) ;
Rodó, Carlota (Hospital Universitari Vall d'Hebron) ;
Garcia-Manau, Pablo (Hospital Universitari Vall d'Hebron) ;
Sanchez-Duran, María Ángeles (Hospital Universitari Vall d'Hebron) ;
Pancorbo, María (Hospital Universitari Vall d'Hebron) ;
Forcada, Cristina (Hospital Universitari Vall d'Hebron) ;
Murcia-Oliveras, María Teresa (Hospital Universitari Vall d'Hebron) ;
Perestelo, Ana (Hospital Universitari Vall d'Hebron) ;
Armengol-Alsina, Mireia (Hospital Universitari Vall d'Hebron) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron) ;
Carreras Moratonas, Elena (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Pre-eclampsia (PE) and small for gestational age (SGA) can be predicted from the first trimester. The most widely used algorithm worldwide is the Fetal Medicine Foundation (FMF) algorithm. The recently described Gaussian algorithm has reported excellent results although it is unlikely to be externally validated. [...]
2022 - 10.1002/ijgo.14306
International Journal of Gynaecology and Obstetrics, Vol. 160 (july 2022) , p. 150-160
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7.
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6 p, 869.6 KB |
Reference values for interleukin-6 in the amniotic fluid of asymptomatic pregnant women
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del Barco, Ester (Hospital Universitari Vall d'Hebron) ;
Franco-Jarava, Clara (Hospital Universitari Vall d'Hebron) ;
Vargas, Mireia (Hospital Universitari Vall d'Hebron) ;
Maiz, Nerea (Hospital Universitari Vall d'Hebron) ;
Arévalo, Silvia (Hospital Universitari Vall d'Hebron) ;
Sánchez, Maria Ángeles (Hospital Universitari Vall d'Hebron) ;
Avilés García, M. T. (Hospital Universitari Vall d'Hebron) ;
Rodó, Carlota (Hospital Universitari Vall d'Hebron) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron) ;
Goya, M (Hospital Universitari Vall d'Hebron) ;
Hernández-González, Manuel (Hospital Universitari Vall d'Hebron) ;
Carreras Moratonas, Elena (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Nowadays, proinflammatory factors are considered to play an important role in the pathophysiology of threatened preterm labor or chorioamnionitis. The aim of this study was to establish the normal reference range for interleukin-6 (IL-6) levels in the amniotic fluid and to identify factors which may alter this value. [...]
2023 - 10.1111/aogs.14524
Acta Obstetricia et Gynecologica Scandinavica, Vol. 102 (march 2023) , p. 480-485
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11 p, 822.3 KB |
Abnormal Maternal Body Mass Index and Customized Fetal Weight Charts : Improving the Identification of Small for Gestational Age Fetuses and Newborns
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González González, Nieves Luisa (Universidad de La Laguna) ;
González Dávila, Enrique (Universidad de La Laguna) ;
González Martín, Agustina (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Armas, Marina (Evangelisches Krakenhaus König Elisabeth Herzberge) ;
Tascón, Laura (Universidad de La Laguna) ;
Farràs Llobet, Alba (Hospital Universitari Vall d'Hebron) ;
Higueras, Teresa (Hospital Universitari Vall d'Hebron) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron) ;
Carreras Moratonas, Elena (Hospital Universitari Vall d'Hebron) ;
Goya, M (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Background: Obesity and thinness are serious diseases, but cases with abnormal maternal weight have not been excluded from the calculations in the construction of customized fetal growth curves (CCs). [...]
2023 - 10.3390/nu15030587
Nutrients, Vol. 15 (january 2023)
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14 p, 466.8 KB |
The Fetal Growth Restriction at Term Managed by Angiogenic Factors Versus Feto-Maternal Doppler (GRAFD) Trial to Avoid Adverse Perinatal Outcomes : Protocol for a Multicenter, Open-Label, Randomized Controlled Trial
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Garcia-Manau, Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bonacina, Erika (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martin-Alonso, Raquel (Universidad Francisco de Vitoria) ;
Martin, Lourdes (Universitat Rovira i Virgili) ;
Palacios, Ana (Universidad Miguel Hernández de Elche) ;
Sanchez, Maria Luisa (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Lesmes Heredia, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hurtado, Ivan (Institut Germans Trias i Pujol) ;
Perez, Esther (Universidad de Oviedo) ;
Tubau Navarra, Albert (Universitat de les Illes Balears) ;
Ibañez, Patricia (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Alcoz, Marina (Universitat de Vic) ;
Valiño, Nuria (Universidade da Coruña) ;
Moreno, Elena (Universidad Miguel Hernández de Elche) ;
Borrero, Carlota (Universidad de Sevilla) ;
Garcia, Esperanza (Universitat Internacional de Catalunya) ;
Lopez-Quesada, Eva (Universitat de Barcelona) ;
Díaz Rodríguez, Sonia (Universidad Europea de Madrid) ;
Broullon, Jose Roman (Universidad de Cádiz) ;
Teixidor, Mireia (Universitat de Girona) ;
Chulilla, Carolina (Universidad de La Laguna) ;
Gil, Maria M (Universidad Francisco de Vitoria) ;
Lopez, Monica (Universitat Rovira i Virgili) ;
Candela-Hidalgo, Amparo (Universidad Miguel Hernández de Elche) ;
Salinas-Amoros, Andrea (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Moreno Baró, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Morra, Francesca (Institut Germans Trias i Pujol) ;
Vaquerizo, Oscar (Universidad de Oviedo) ;
Soriano, Beatriz (Universitat de les Illes Balears) ;
Fabre, Marta (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Gomez-Valencia, Elena (Universitat de Vic) ;
Cuiña, Ana (Universidade da Coruña) ;
Alayon, Nicolas (Universidad Miguel Hernández de Elche) ;
Sainz, Jose Antonio (Universidad de Sevilla) ;
Vives, Angels (Universitat Internacional de Catalunya) ;
Esteve, Esther (Universitat de Barcelona) ;
Ocaña, Vanesa (Universidad Europea de Madrid) ;
López, Miguel Ángel (Universidad de Cádiz) ;
Maroto, Anna (Universitat de Girona) ;
Carreras Moratonas, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Fetal smallness affects 10% of pregnancies. Small fetuses are at a higher risk of adverse outcomes. Their management using estimated fetal weight and feto-maternal Doppler has a high sensitivity for adverse outcomes; however, more than 60% of fetuses are electively delivered at 37 to 38 weeks. [...]
2022 - 10.2196/37452
JMIR Research Protocols, Vol. 11 (october 2022)
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10.
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12 p, 517.8 KB |
Maternal and Perinatal Outcomes Associated With Extremely High Values for the sFlt-1 (Soluble fms-Like Tyrosine Kinase 1)/PlGF (Placental Growth Factor) Ratio
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Villalaín, Cecilia (Universidad Complutense de Madrid) ;
Herraiz, Ignacio (Universidad Complutense de Madrid) ;
Valle, Leonor (Hospital Universitario Materno-Infantil de Las Palmas de Gran Canaria) ;
Mendoza, Manel (Hospital Universitari Vall d'Hebron) ;
Delgado, Juan Luis (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Vázquez-Fernández, María (Hospital Universitario Central de Asturias) ;
Martínez-Uriarte, Juan (Hospital Virgen de La Luz (Cuenca)) ;
Melchor, Íñigo (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Caamiña Álvarez, Sara (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Fernández-Oliva, Antoni (Institut d'Investigació Biomèdica Sant Pau) ;
Villar, Olga Patricia (Universidad Complutense de Madrid) ;
Galindo Tixaire, Alberto (Universidad Complutense de Madrid) ;
Universitat Autònoma de Barcelona
There is little knowledge about the significance of extremely high values (>655) for the ratio of lt-1 (soluble fms-like tyrosine kinase 1) to Pl (placental growth factor). We aim to describe the time-to-delivery interval and maternal and perinatal outcomes when such values are demonstrated while assessing suspected or confirmed placental dysfunction based on clinical or sonographic criteria. [...]
2020 - 10.1161/JAHA.119.015548
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 9 (april 2020)
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