1.
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32 p, 1.1 MB |
Paper-based biosensors for cancer diagnostics
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Pereira, Claudia (Institut Català de Nanociència i Nanotecnologia) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Idili, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Gomis, Roger R. (Institut de Recerca Biomèdica) ;
Rodrigues, Lígia (Universidade do Minho. Centro de Engenharia Biológica) ;
Sales, Goreti (Universidade de Coimbra. Departmento de Enginharia Química) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
The implementation of a wide diagnostic campaign to diagnose cancer early could save millions of lives and billions of dollars every year. Unfortunately, cancer diagnosis is extremely complicated and current approaches rely on the use of expensive equipment and specialized personnel, which hamper their deployment in low- and middle-income settings. [...]
2022 - 10.1016/j.trechm.2022.03.005
Trends in Chemistry, Vol. 4, issue 6 (June 2022) , p. 554-567
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2.
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9 p, 2.5 MB |
A novel ratiometric fluorescent approach for the modulation of the ydnamic range of lateral flow immunoassays
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Sena-Torralba, Amadeo (Institut Català de Nanociència i Nanotecnologia) ;
Torné-Morató, Helena (Institut Català de Nanociència i Nanotecnologia) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Ranjbar, Saba (Institut Català de Nanociència i Nanotecnologia) ;
Nejad, Mohammad Amin Farahmand (Institut Català de Nanociència i Nanotecnologia) ;
Álvarez Diduk, Ruslan (Institut Català de Nanociència i Nanotecnologia) ;
Idili, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Hormozi-Nezhad, M.R. (Sharif University of Technology. Department of Chemistry) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
The majority of lateral flow assays (LFAs) use single-color optical labels to provide a qualitative naked-eye detection, however this detection method displays two important limitations. First, the use of a single-color label makes the LFA prone to results misinterpretation. [...]
2022 - 10.1002/admt.202101450
Advanced Materials Technologies, Vol. 7, issue 8 (August 2022) , art. 2101450
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3.
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24 p, 1.8 MB |
Wearable and fully printed microfluidic nanosensor for sweat rate, conductivity, and copper detection with healthcare applications
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Yang, Qiuyue (Institut Català de Nanociència i Nanotecnologia) ;
Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia) ;
Abarintos, Vernalyn (Institut Català de Nanociència i Nanotecnologia) ;
Aroca, Miguel A. (Universidad de Los Andes. Departamento de Ingeniería Eléctrica e Ingeniería Electrónica) ;
Osma, Johann F. (Universidad de Los Andes. Departamento de Ingeniería Eléctrica e Ingeniería Electrónica) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia) ;
Universitat Autònoma de Barcelona
Wearables are becoming pervasive in our society, but they are still mainly based on physical sensors with just few optical and electrochemical exceptions. Sweat, amongst other body fluids, is easily and non-invasively accessible, abundant, and relatively poor of interfering species. [...]
2022 - 10.1016/j.bios.2022.114005
Biosensors and bioelectronics, Vol. 202 (April 2022) , art. 114005
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4.
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5.
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18 p, 5.3 MB |
Integrated devices for non-invasive diagnostics
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Ates, Hatice Ceren (Freiburg Centre for Interactive Materials and Bioinspired Technology) ;
Brunauer, Anna (University of Freiburg. Department of Microsystems Engineering) ;
von Stetten, Felix (Hahn-Schickard) ;
Urban, Gerald A. (University of Freiburg. Department of Microsystems Engineering) ;
Güder, Firat (Imperial College London. Department of Bioengineering) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia) ;
Früh, Susanna Maria (Hahn-Schickard) ;
Dincer, Can (University of Freiburg. Department of Microsystems Engineering)
"Sample-in-answer-out" type integrated diagnostic devices have been widely recognized as the ultimate solution to simplify testing across healthcare systems. Such systems are equipped with advanced fluidic, mechanical, chemical, biological, and electronic components to handle patient samples without any manual steps therefore have the potential to accelerate intervention and improve patient outcomes. [...]
2021 - 10.1002/adfm.202010388
Advanced functional materials, Vol. 31, issue 15 (April 2021) , art. 2010388
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6.
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Label-free and reagentless electrochemical genosensor based on graphene acid for meat adulteration detection
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Flauzino, J. M. R. (Institut Català de Nanociència i Nanotecnologia) ;
Nguyen, Emily P. (Institut Català de Nanociència i Nanotecnologia) ;
Yang, Qiuyue (Institut Català de Nanociència i Nanotecnologia) ;
Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia) ;
Panáček, David (Institut Català de Nanociència i Nanotecnologia) ;
Brito-Madurro, Ana G. (Federal University of Uberlândia. Institute of Biotechnology (Brazil)) ;
Madurro, João M. (Federal University of Uberlândia. Institute of Chemistry (Brazil)) ;
Bakandritsos, Aristides (VŠB-Technical University of Ostrava. Centre of Energy and Environmental Technologies. Nanotechnology Centre (Czech Republic)) ;
Otyepka, Michal (VŠB-Technical University of Ostrava. IT4Innovations (Czech Republic)) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
With the increased demand for beef in emerging markets, the development of quality-control diagnostics that are fast, cheap and easy to handle is essential. Especially where beef must be free from pork residues, due to religious, cultural or allergic reasons, the availability of such diagnostic tools is crucial. [...]
2022 - 10.1016/j.bios.2021.113628
Biosensors and bioelectronics, Vol. 195 (January 2022) , art. 113628
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7.
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15 p, 9.7 MB |
Low-Cost, User-Friendly, All-Integrated Smartphone-Based Microplate Reader for Optical-Based Biological and Chemical Analyses
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Bergua Canudo, José Francisco (Institut Català de Nanociència i Nanotecnologia) ;
Álvarez Diduk, Ruslan (Institut Català de Nanociència i Nanotecnologia) ;
Idili, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Maymó, M. (Institut Català de Nanociència i Nanotecnologia) ;
Hu, Liming (Institut Català de Nanociència i Nanotecnologia) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
The quantitative detection of different molecular targets is of utmost importance for a variety of human activities, ranging from healthcare to environmental studies. Bioanalytical methods have been developed to solve this and to achieve the quantification of multiple targets from small volume samples. [...]
2022 - 10.1021/acs.analchem.1c04491
Analytical chemistry, Vol. 94, Issue 2 (January 2022) , p. 1271-1285
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8.
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6 p, 1.7 MB |
Selection and characterisation of bioreceptors to develop nanoparticle-based lateral-flow immunoassays in the context of the SARS-CoV-2 outbreak
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Hu, Liming (Institut Català de Nanociència i Nanotecnologia) ;
Calucho, Enric (Institut Català de Nanociència i Nanotecnologia) ;
Fuentes-Chust, Celia (Institut Català de Nanociència i Nanotecnologia) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Idili, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Álvarez Diduk, Ruslan (Institut Català de Nanociència i Nanotecnologia) ;
Rivas, Lourdes (Institut Català de Nanociència i Nanotecnologia) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
This manuscript aims at raising the attention of the scientific community to the need for better characterised bioreceptors for fast development of point-of-care diagnostic devices able to support mass frequency testing. [...]
2022 - 10.1039/d2lc00486k
Lab on a chip, Vol. 22, issue 16 (Aug. 2022) , p. 2938-2943
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9.
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14 p, 7.9 MB |
Graphene nanobeacons with high-affinity pockets for combined, selective, and effective decontamination and reagentless detection of heavy metals
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Panáček, David (Institut Català de Nanociència i Nanotecnologia) ;
Zdražil, Lukáš (Palacký University Olomouc. Department of Physical Chemistry) ;
Langer, Michal (Palacký University Olomouc. Department of Physical Chemistry) ;
Šedajová, Veronika (Palacký University Olomouc. Department of Physical Chemistry) ;
Baďura, Zdeněk (Palacký University Olomouc. Department of Experimental Physics) ;
Zoppellaro, Georgio (Czech Advanced Technology and Research Institute. Regional Centre of Advanced Technologies and Materials) ;
Yang, Qiuyue (Institut Català de Nanociència i Nanotecnologia) ;
Nguyen, Emily P. (Institut Català de Nanociència i Nanotecnologia) ;
Álvarez Diduk, Ruslan (Institut Català de Nanociència i Nanotecnologia) ;
Hrubý, Vítězslav (Palacký University Olomouc. Department of Physical Chemistry) ;
Kolařík, Jan (Czech Advanced Technology and Research Institute. Regional Centre of Advanced Technologies and Materials) ;
Chalmpes, Nikolaos (University of Ioannina. Department of Materials Science & Engineering) ;
Bourlinos, Athanasios B. (University of Ioannina. Physics Department) ;
Zboril, Radek (VŠB-Technical University of Ostrava. Nanotechnology Centre) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia) ;
Bakandritsos, Aristides (VŠB-Technical University of Ostrava. Nanotechnology Centre) ;
Otyepka, Michal (VŠB-Technical University of Ostrava. IT4Innovations)
Access to clean water for drinking, sanitation, and irrigation is a major sustainable development goal of the United Nations. Thus, technologies for cleaning water and quality-monitoring must become widely accessible and of low-cost, while being effective, selective, sustainable, and eco-friendly. [...]
2022 - 10.1002/smll.202201003
Small, Vol. 18, issue 33 (Aug. 2022) , art. 2201003
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10.
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12 p, 1.7 MB |
A Programmable electrochemical Y-shaped DNA scaffold sensor for the single-step detection of antibodies and proteins in untreated biological fluids
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Idili, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Bonini, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Álvarez Diduk, Ruslan (Institut Català de Nanociència i Nanotecnologia) ;
Di Francesco, Fabio (Università degli Studi di Pisa. Dipartimento di Chimica e Chimica Industriale) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
Proteins and antibodies are key biomarkers for diagnosing and monitoring specific medical conditions. Currently, gold standard techniques used for their quantification require laborious multi-step procedures, involving high costs and slow response times. [...]
2022 - 10.1002/adfm.202201881
Advanced functional materials, Vol. 32, issue 37 (Sep. 2022) , art. 2201881
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