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The Influence of Hormonal Factors on the Risk of Developing Cervical Cancer and Pre-Cancer : results from the EPIC Cohort
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Roura, Esther (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Travier, Noémie (Institut Català d'Oncologia) ;
Waterboer, Tim (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
De Sanjose, Silvia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Bosch José, Francesc Xavier 1947- (Institut Català d'Oncologia) ;
Pawlita, Michael (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Pala, Valeria (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy) ;
Weiderpass, Elisabete (Folkhälsan Research Center, Helsinki, Finland) ;
Margall, Núria (Institut d'Investigació Biomèdica Sant Pau) ;
Dillner, Joakim (Karolinska Institutet (Estocolm, Suècia)) ;
Gram, Inger T. (UiT The Arctic University of Norway, Tromsø, Norway) ;
Tjønneland, Anne (Danish Cancer Society Research Center, Copenhagen, Denmark) ;
Munk, Christian (Danish Cancer Society Research Center, Copenhagen, Denmark) ;
Palli, Domenico (Cancer Research and Prevention Institute-ISPO, Florence, Italy) ;
Khaw, Kay-Tee (University of Cambridge) ;
Overvad, Kim (Aarhus University, Aarhus, Denmark) ;
Clavel-Chapelon, Françoise (Institut Gustave Roussy (Villejuif, França)) ;
Mesrine, Sylvie (Institut Gustave Roussy (Villejuif, França)) ;
Fournier, Agnès (Institut Gustave Roussy (Villejuif, França)) ;
Fortner, Renée T. (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Ose, Jennifer (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Steffen, Annika (German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany) ;
Trichopoulou, Antonia (Hellenic Health Foundation, Athens, Greece) ;
Lagiou, Pagona (Harvard School of Public Health, Boston, United States of America) ;
Orfanos, Philippos (University of Athens Medical School, Athens, Greece) ;
Masala, Giovanna (Cancer Research and Prevention Institute-ISPO, Florence, Italy) ;
Tumino, Rosario ("Civic-M.P. Arezzo" Hospital, Ragusa, Italy) ;
Sacerdote, Carlotta (Centre for Cancer Epidemiology and Prevention (CPO Piemonte), Turin, Italy) ;
Polidoro, Silvia (Human Genetics Foundation (HuGeF), Turin, Italy) ;
Mattiello, Amalia (Federico II University, Naples, Italy) ;
Lund, Eiliv (UiT The Arctic University of Norway, Tromsø, Norway) ;
Peeters, Petra H. (University Medical Center Utrecht, Utrecht, The Netherlands) ;
Bueno-de-Mesquita, H. Bas (University of Malaya, Kuala Lumpur, Malaysia) ;
Quirós, J. Ramón (Dirección de Salud Pública de Asturias) ;
Sánchez, María-José (Instituto de Investigación Sanitaria de Granada) ;
Navarro Villanueva, Carmen (Universidad de Murcia) ;
Barricarte, Aurelio (Instituto de Investigación Sanitaria de Navarra) ;
Larrañaga, Nerea (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Ekström, Johanna (Lund University, Medicon Village, Lund, Sweden) ;
Lindquist, David (Department of Radiation Sciences, Umeå University, Umeå, Sweden) ;
Idahl, Annika (Umeå University, Umeå, Sweden) ;
Travis, Ruth C. (University of Oxford, Oxford, United Kingdom) ;
Merritt, Melissa A. (Imperial College London, London, United Kingdom) ;
Gunter, Marc J. (Imperial College London, London, United Kingdom) ;
Rinaldi, Sabina (International Agency for Research on Cancer, Lyon, France) ;
Tommasino, Massimo (International Agency for Research on Cancer, Lyon, France) ;
Franceschi, Silvia (International Agency for Research on Cancer, Lyon, France) ;
Riboli, Elio (Imperial College London, London, United Kingdom) ;
Castellsagué, Xavier (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Universitat Autònoma de Barcelona
In addition to HPV, high parity and hormonal contraceptives have been associated with cervical cancer (CC). However, most of the evidence comes from retrospective case-control studies. The aim of this study is to prospectively evaluate associations between hormonal factors and risk of developing cervical intraepithelial neoplasia grade 3 (CIN3)/carcinoma in situ (CIS) and invasive cervical cancer (ICC). [...]
2016 -  10.1371/journal.pone.0147029
PloS one, Vol. 11 (january 2016)
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