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Articles, 2 records found
Articles 2 records found  
1.
13 p, 2.1 MB Peptide Assembly on the Membrane Determines the HIV-1 Inhibitory Activity of Dual-Targeting Fusion Inhibitor Peptides / Gómara Elena, María José (Institut de Química avançada de Catalunya (IQAC-CSIC)) ; Pérez, Yolanda (Institut de Química avançada de Catalunya (IQAC-CSIC)) ; Martinez, Javier P. (Universitat Pompeu Fabra) ; Barnadas Rodríguez, Ramon (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Schultz, Anke (Fraunhofer Institute for Biomedical Engineering (Sulzbach, Alemanya)) ; von Briesen, Hagen (Fraunhofer Institute for Biomedical Engineering (Sulzbach, Alemanya)) ; Perálvarez Marín, Alejandro (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Meyerhans, Andreas (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Haro, Isabel (Institut de Química avançada de Catalunya (IQAC-CSIC))
Novel strategies in the design of HIV-I fusion/entry inhibitors are based on the construction of dual- targeting fusion proteins and peptides with synergistic antiviral effects. In this work we describe the design of dual -targeting peptides composed of peptide domains of E2 and El envelope proteins from Human Pegivirus with the aim of targeting both the loop region and the fusion peptide domains of HIV-I gp41. [...]
2019 - 10.1038/s41598-019-40125-4
Scientific reports, Vol. 9 (2019) , art. 3257  
2.
12 p, 1.2 MB Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21 / Carreras Sureda, Amado, 1986- (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Rubio Moscardo, Fanny (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Argilaguet, Jordi (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Kiefer, Kerstin (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Meyerhans, Andreas (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vicente, Rubén (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut)
Single nucleotide polymorphisms (SNPs) located in the chromosome region 17q12-q21 are risk factors for asthma. Particularly, there are cis-regulatory haplotypes within this region that regulate differentially the expression levels of ORMDL3, GSDMB and ZPBP2 genes. [...]
2016 - 10.1371/journal.pone.0166414
PloS one, Vol. 11 Núm. 11 (November 2016)  

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