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21 p, 5.5 MB |
Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
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Korvenlaita, Nea (A.I. Virtanen Institute for Molecular Sciences) ;
Gómez-Budia, Mireia (A.I. Virtanen Institute for Molecular Sciences) ;
Scoyni, Flavia (A.I. Virtanen Institute for Molecular Sciences) ;
Pistono, Cristiana (A.I. Virtanen Institute for Molecular Sciences) ;
Giudice, Luca (University of Verona) ;
Eamen, Shaila (A.I. Virtanen Institute for Molecular Sciences) ;
Loppi, Sanna (University of Arizona) ;
de Sande, Ana Hernández (A.I. Virtanen Institute for Molecular Sciences) ;
Huremagic, Benjamin (KU Leuven) ;
Bouvy-Liivrand, Maria (University of Eastern Finland. School of Medicine) ;
Heinäniemi, Merja (School of Medicine) ;
Kaikkonen, Minna U. (A.I. Virtanen Institute for Molecular Sciences) ;
Cheng, Lesley (La Trobe University) ;
Hill, Andrew F. (Victoria University) ;
Kanninen, Katja M. (A.I. Virtanen Institute for Molecular Sciences) ;
Jenster, Guido W. (Erasmus University Medical Center) ;
van Royen, Martin E. (Erasmus University Medical Center) ;
Ramiro, Laura (Universitat Autònoma de Barcelona) ;
Montaner, Joan (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Batkova, Tereza (St. Anne's University Hospital and Masaryk University) ;
Mikulik, Robert (St. Anne's University Hospital and Masaryk University) ;
Giugno, Rosalba (University of Verona) ;
Jolkkonen, Jukka (A.I. Virtanen Institute for Molecular Sciences) ;
Korhonen, Paula (A.I. Virtanen Institute for Molecular Sciences) ;
Malm, Tarja (A.I. Virtanen Institute for Molecular Sciences)
Hypoxia induces changes in the secretion of extracellular vesicles (EVs) in several non-neuronal cells and pathological conditions. EVs are packed with biomolecules, such as microRNA(miR)-21-5p, which respond to hypoxia. [...]
2023 -  10.1002/jev2.12297
Journal of extracellular vesicles, Vol. 12 (january 2023)
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12 p, 545.5 KB |
Endovascular equipoise shift in a phase III randomized clinical trial of sonothrombolysis for acute ischemic stroke
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Alexandrov, Andrei V. (University of Tennessee Health Science Center) ;
Tsivgoulis, Georgios (University of Tennessee Health Science Center) ;
Köhrmann, Martin (Universitaetsklinikum Erlangen) ;
Katsanos, Aristeidis H. (University General Hospital Attikon (Haidari, Grècia)) ;
Soinne, Lauri (Helsinki University Hospital and Clinical Neurosciences) ;
Barreto, Andrew D. (University of Texas Health Science Center at Houston) ;
Rothlisberger, Travis (Cerevast Therapeutics, Inc., Redmond) ;
Sharma, Vijay K. (Yong Loo Lin School of Medicine) ;
Mikulik, Robert (St. Anne's University Hospital in Brno) ;
Muir, Keith W. (University of Glasgow) ;
Levi, Christopher R. (John Hunter Hospital) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Saqqur, Maher (University of Alberta) ;
Mavridis, Dimitris (University of Ioannina) ;
Psaltopoulou, Theodora (Kapodistrian University of Athens) ;
Vosko, Milan R. (Kepler University Hospital) ;
Fiebach, Jochen B. (Charité-University Medicine Berlin) ;
Mandava, Pitchaiah (Baylor College of Medicine) ;
Kent, Thomas A. (Baylor College of Medicine) ;
Alexandrov, Andrei V (University of Tennessee Health Science Center) ;
Schellinger, Peter D. (Ruhr University Bochum) ;
Universitat Autònoma de Barcelona
Results of our recently published phase III randomized clinical trial of ultrasound-enhanced thrombolysis (sonothrombolysis) using an operator-independent, high frequency ultrasound device revealed heterogeneity of patient recruitment among centers. [...]
2019 - 10.1177/1756286419860652
Therapeutic Advances in Neurological Disorders, Vol. 12 (july 2019)
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28 p, 504.2 KB |
Action Plan for Stroke in Europe 2018-2030
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Norrving, Bo (Lund University. Department of Clinical Sciences) ;
Barrick, Jon (Stroke Alliance for Europe) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dichgans, Martin (Ludwig-Maximilians University) ;
Cordonnier, Charlotte (CHU Lille. Department of Neurology) ;
Guekht, Alla (Russian National Research Medical University) ;
Kutluk, Kursad (University of Dokuz Eylul. Department of Neurology) ;
Mikulik, Robert (Masaryk University) ;
Wardlaw, Joanna (University of Edinburgh) ;
Richard, Edo (Radboud University Medical Centre) ;
Nabavi, Darius (Vivantes Hospital Neukölln) ;
Molina, Carlos (Hospital Universitari Vall d'Hebron) ;
Bath, P. M. W (University of Nottingham) ;
Stibrant Sunnerhagen, Katharina (Sahlgrenska University Hospital (Suècia)) ;
Rudd, Anthony (Guy's and St Thomas' NHS Foundation Trust) ;
Drummond, Avril (School of Health Sciences, University of Nottingham) ;
Planas, Anna Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Caso, Valeria (University of Perugia. Department of Medicine and Cardiovascular Medicine) ;
Universitat Autònoma de Barcelona
Two previous pan-European consensus meetings, the 1995 and 2006 Helsingborg meetings, were convened to review the scientific evidence and the state of current services to identify priorities for research and development and to set targets for the development of stroke care for the decade to follow. [...]
2018 - 10.1177/2396987318808719
European Stroke Journal, Vol. 3 Núm. 4 (october 2018) , p. 309-336
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4.
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20 p, 1.7 MB |
Timing of Recanalization and Functional Recovery in Acute Ischemic Stroke
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Tsivgoulis, Georgios (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Saqqur, Maher (Department of Neuroscience, Hamad General Hospital, Doha) ;
Sharma, Vijay K. (Division of Neurology, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore) ;
Brunser, Alejandro (Department of Emergency Medicine, Clinica Alemana of Santiago, University of Desarrollo, Santiago) ;
Eggers, Jürgen (Department of Neurology, Sana Hospital Lubeck, Lübeck) ;
Mikulik, Robert (Medical Faculty, Masaryk University, Brno) ;
Katsanos, Aristeidis H. (Department of Neurology, University of Ioannina School of Medicine, Ioannina) ;
Sergentanis, Theodore N. (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ;
Vadikolias, Konstantinos (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Perren, Fabienne (Geneva University Hospitals (Suïssa)) ;
Rubiera Del Fueyo, Marta A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bavarsad Shahripour, Reza (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ;
Nguyen, Huy Thang (Department of Cerebrovascular Disease, 115 The People Hospital, Ho Chi Minh) ;
Martínez-Sánchez, Patricia (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Safouris, Apostolos (Stroke Unit, Department of Neurology, Brugmann University Hospital, Brussels) ;
Heliopoulos, Ioannis (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Shuaib, Ashfaq (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ;
Derksen, Carol (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ;
Voumvourakis, Konstantinos (University General Hospital Attikon (Haidari, Grècia)) ;
Psaltopoulou, Theodora (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ;
Alexandrov, Andrei V (Department of Neurology, University of Tennessee Health Science Center, Memphis, TN) ;
Alexandrov, Andrei V. (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ;
Universitat Autònoma de Barcelona
Although onset-to-treatment time is associated with early clinical recovery in acute ischemic stroke (AIS) patients treated with intravenous tissue plasminogen activator (tPA), the effect of the timing of tPA-induced recanalization on functional outcomes remains debatable. [...]
2020 - 10.5853/jos.2019.01648
Journal of Stroke, Vol. 22 (january 2020) , p. 130-140
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