Results overview: Found 4 records in 0.02 seconds.
Articles, 3 records found
Research literature, 1 records found
Articles 3 records found  
1.
15 p, 2.1 MB Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif / Molinos-Albert, Luis Manuel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bilbao, Eneritz (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Agulló, Luis (Universitat de Vic. Departament de Biociències) ; Marfil, Silvia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; García, Elisabet (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez de la Concepción, Maria Luisa (Institut Germans Trias i Pujol) ; Izquierdo-Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vilaplana, Cristina (Institut Germans Trias i Pujol. Unitat de Tuberculosi Experimental) ; Nieto-Garai, Jon A. (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Contreras, F. Xabier (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Floor, Martin (Universitat de Vic. Departament de Biociències) ; Cardona, Pere J. (Institut Germans Trias i Pujol. Unitat de Tuberculosi Experimental) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Villà-Freixa, Jordi (Universitat de Vic. Departament de Biociències) ; Lorizate, Maier (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
The HIV-1 gp41 Membrane Proximal External Region (MPER) is recognized by broadly neutralizing antibodies and represents a promising vaccine target. However, MPER immunogenicity and antibody activity are influenced by membrane lipids. [...]
2017 - 10.1038/srep40800
Scientific Reports, gener 2017, p. 1-15  
2.
9 p, 190.7 KB Predictors of severe sepsis among patients hospitalized for community-acquired pneumonia / Montull Veiga, Beatriz (Hospital Universitario y Politécnico La Fe (València, País Valencià)) ; Menéndez Villanueva, Rosario (Hospital Universitario y Politécnico La Fe (València, País Valencià)) ; Torres, Antoni (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Reyes Calzada, Soledad María (Hospital Universitario y Politécnico La Fe (València, País Valencià)) ; Méndez, Raúl (Hospital Universitario y Politécnico La Fe (València, País Valencià)) ; Zalacaín, Rafael (Hospital Universitario Cruces (Barakaldo, Biscaia)) ; Capelastegui, Alberto (Hospital de Galdakao (Usansolo, Biscaia)) ; Rajas, Olga (Hospital Universitario de la Princesa (Madrid)) ; Borderías, Luis (Hospital San Jorge (Osca, Aragó)) ; Martín Villasclaras, Juan (Hospital Regional Universitario Carlos Haya (Málaga)) ; Bello, Salvador (Hospital Universitario Miguel Servet (Zaragoza)) ; Alfageme, Inmaculada (Hospital de Valme (Sevilla)) ; Rodríguez de Castro, Felipe (Hospital Universitario de Gran Canaria) ; Rello, Jordi (Hospital Joan XXIII (Tarragona)) ; Molinos, Luis (Hospital Universitario Central de Asturias (Oviedo)) ; Ruiz Manzano, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Background: Severe sepsis, may be present on hospital arrival in approximately one-third of patients with community-acquired pneumonia (CAP). Objective: To determine the host characteristics and micro-organisms associated with severe sepsis in patients hospitalized with CAP. [...]
2016 - 10.1371/journal.pone.0145929
PloS one, Vol. 11 Núm. 1 (January 2016)  
3.
18 p, 1.7 MB Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals / Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Molinos-Albert, Luis Manuel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez de la Concepción, Maria Luisa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Marfil, Silvia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; García, Elisabet (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Derking, Ronald (University of Amsterdam) ; Sanders, Rogier W. (University of Amsterdam) ; Clotet i Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco Arbués, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site (CD4bs antibodies), can protect from infection by HIV-1, and their elicitation may be an interesting goal for any vaccination strategy. [...]
2015 - 10.1371/journal.pone.0120648
PLoS One, Vol. 10, No. 3 (March 2015) , p. e0120648  

Research literature 1 records found  
1.
163 p, 3.6 MB Targeting a major HIV-1 vulnerability region : : the gp41 membrane proximal external region : balance between neutralizing and non-neutralizing antibodies and implications for vaccine design / Molinos Albert, Luis Manuel ; Blanco Arbués, Julià, dir. ; Carrillo Molina, Jorge, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
La generació d'anticossos àmpliament neutralitzants contra el VIH-1 es el principal objectiu d'una vacuna que sigui capaç de controlar l'epidèmia causada per aquest virus. La glicoproteïna de l'embolcall del VIH-1 es l'únic antigen viral exposat a la membrana del virus y la principal diana de respostes humorals protectores. [...]
La generación de anticuerpos ampliamente neutralizantes contra el VIH-1 es el principal objetivo de una vacuna que sea capaz de controlar la epidemia causada por el virus. La glicoproteína de la envuelta del VIH-1 es el único antígeno viral expuesto en la membrana del virus y la principal diana de respuestas humorales protectoras. [...]
The elicitation of broadly neutralizing antibodies (bNAbs) against HIV-1 constitutes the major goal of an effective vaccine able to control the epidemic caused by this virus. The HIV-1 envelope glycoprotein is the only viral antigen exposed on the surface of the virus and the main target of protective humoral responses. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  

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