Results overview: Found 5 records in 0.02 seconds.
Articles, 4 records found
Research literature, 1 records found
Articles 4 records found  
1.
13 p, 6.0 MB Mesenchymal stem cells induce expression of cD73 in human monocytes in vitro and in a swine model of myocardial infarction in vivo / Monguió-Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Franquesa, Marcella (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayes-Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Borràs,Francesc E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia)
The ectoenzymes CD39 and CD73 regulate the purinergic signaling through the hydrolysis of adenosine triphosphate (ATP)/ADP to AMP and to adenosine (Ado), respectively. This shifts the pro-inflammatory milieu induced by extracellular ATP to the anti- inflammatory regulation by Ado. [...]
2017 - 10.3389/fimmu.2017.01577
Frontiers in immunology, Vol. 8 (november 2017) , p. 1-13  
2.
15 p, 2.3 MB Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine / Monguió Tortajada, Marta (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Pujal, Josep Maria (Universitat de Girona. Laboratori de processament cel·lular) ; Aran Canals, Gemma (Institut Germans Trias i Pujol) ; Sanjurjo, Lucía (Institut Germans Trias i Pujol) ; Franquesa, Marcel·la (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Borràs, Francesc E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity. Umbilical cord mesenchymal stem cells (UCMSCs) have powerful regenerative and immunomodulatory potential, and their secreted extracellular vesicles (EVs) are envisaged as a promising natural source of nanoparticles to increase outcomes in organ transplantation and control inflammatory diseases. [...]
2017 - 10.7150/thno.16154
Theranostics, Vol. 7 Núm. 2 (2017) , p. 270-284  
3.
14 p, 1.9 MB Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes / Monguió Tortajada, Marta (Institut Germans Trias i Pujol) ; Franquesa, Marcella (Institut Germans Trias i Pujol) ; Sarrias, Maria-Rosa (Network for Biomedical Research in Hepatic and Digestive Diseases (CIBERehd)) ; Borràs, Francesc E. (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
TLR sensing of pathogens triggers monocyte activation to initiate the host innate immune response to infection. Monocytes can dynamically adapt to different TLR agonists inducing different patterns of inflammatory response, and the sequence of exposure to TLRs can dramatically modulate cell activation. [...]
2018 - 10.1038/s41419-018-0520-2
Cell death and disease, Vol. 9 (May 2018) , art. 499  
4.
9 p, 1.4 MB Size-Exclusion Chromatography-based isolation minimally alters Extracellular Vesicles' characteristics compared to precipitating agents / Gámez Valero, Ana (Institut Germans Trias i Pujol) ; Monguió Tortajada, Marta (Institut Germans Trias i Pujol) ; Carreras Planella, Laura (Institut Germans Trias i Pujol) ; Franquesa, Marcel·la (Institut Germans Trias i Pujol) ; Beyer, Katrin (Institut Germans Trias i Pujol) ; Borràs, Francesc E. (Institut Germans Trias i Pujol)
Extracellular vesicles (EVs) have become an attractive field among the scientific community. Yet, a major challenge is to define a consensus method for EVs isolation. Ultracentrifugation has been the most widely used methodology but rapid methods, including Size Exclusion Chromatography (SEC) and/or precipitating agents such as Polyethylene glycol (PEG) or PRotein Organic Solvent PRecipitation (PROSPR) have emerged. [...]
2016 - 10.1038/srep33641
Scientific reports, Vol. 6 (September 2016)  

Research literature 1 records found  
1.
198 p, 5.7 MB Immunomodulation by mesenchymal stem cells for myocardial regeneration : cellular mechanisms and extracellular vesicles / Monguió Tortajada, Marta, autor. ; Borràs i Serres, Francesc Enric, supervisor acadèmic. ; Jaraquemada, Dolores, supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia.
Les respostes immunològiques descontrolades obstaculitzen la regeneració de teixits danyats i el transplantament d'òrgans, i provoquen al·lèrgies i trastorns autoimmunitaris, causant morbiditat i mortalitat. [...]
Exacerbated immune responses hamper regeneration of injured tissues and organ transplantation, and lead to allergies and autoimmune disorders causing morbidity and mortality. One of these scenarios is the ischaemia-reperfusion injury (IRI) occurring upon myocardial infarction (MI). [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  

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1 Monguió-Tortajada, Marta
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