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1.
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9 p, 1.4 MB |
Heterogeneous rate constant for amorphous silica nanoparticle adsorption on phospholipid monolayers
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Vakurov, Alex (University of Leeds. School of Chemistry) ;
Drummond-Brydson, Rik (University of Leeds. School of Chemical and Process Engineering) ;
William, Nicola (University of Leeds. School of Chemistry) ;
Sanver, Didem (Necmettin Erbakan University. Department of Food Engineering) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Nelson, Andrew L. (University of Leeds. School of Chemistry)
The interaction of amorphous silica nanoparticles with phospholipid monolayers and bilayers has received a great deal of interest in recent years and is of importance for assessing potential cellular toxicity of such species, whether natural or synthesized for the purpose of nanomedical drug delivery and other applications. [...]
2022 -  10.1021/acs.langmuir.1c03155
Langmuir, Vol. 38, issue 18 (May 2022) , p. 5372-5380
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2.
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26 p, 1.5 MB |
The Role of common cell culture media supplements on citrate-stabilized gold nanoparticle protein corona formation, aggregation state, and the consequent impact on cellular uptake
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Barbero, Francesco (Institut Català de Nanociència i Nanotecnologia) ;
Michelini, Sara (University of Salzburg. Department of Biosciences) ;
Moriones, Oscar Hernando (Universitat Autònoma de Barcelona) ;
Patarroyo, Javier (Institut Català de Nanociència i Nanotecnologia) ;
Rosell Aluja, Jordi 1955- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gustà, Muriel F (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vitali, Michele (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martín, Luna (Vall d'Hebron Institut d'Oncologia) ;
Canals, Francesc (Vall d'Hebron Institut d'Oncologia) ;
Duschl, Albert (University of Salzburg. Department of Biosciences) ;
Horejs-Hoeck, Jutta (University of Salzburg. Department of Biosciences) ;
Mondragón, Laura (Institut Català de Nanociència i Nanotecnologia) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Sodium citrate-stabilized gold nanoparticles (AuNPs) are destabilized when dispersed in cell culture media (CCMs). This may promote their aggregation and subsequent sedimentation, or under the proper conditions, their interaction with dispersed proteins can lead to the formation of a NP-stabilizing protein corona. [...]
2022 - 10.1021/acs.bioconjchem.2c00232
Bioconjugate chemistry, Vol. 33, issue 8 (Aug. 2022) , p. 1505-1514
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3.
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13 p, 4.0 MB |
Antibacterial films based on MOF composites that release iodine passively or upon triggering by near-infrared light
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Han, Xu (Institut Català de Nanociència i Nanotecnologia) ;
Boix, Gerard (Institut Català de Nanociència i Nanotecnologia) ;
Balcerzak, Mateusz (Institut Català de Nanociència i Nanotecnologia) ;
Moriones, Oscar Hernando (Universitat Autònoma de Barcelona) ;
Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ;
Cortés Garmendia, M. Pilar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Llagostera Casas, Montserrat (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Imaz, Inhar (Institut Català de Nanociència i Nanotecnologia) ;
Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ;
Boix, Gerard (Institut Català de Nanociència i Nanotecnologia)
Multidrug-resistant bacteria have become a global health problem for which new prophylactic strategies are now needed, including surface-coatings for hospital spaces and medical equipment. This work reports the preparation and functional validation of a metal-organic framework (MOF) based composite for the triggered controlled release of iodine, an antimicrobial element that does not generate resistance. [...]
2022 - 10.1002/adfm.202112902
Advanced functional materials, Vol. 32, issue 19 (May 2022) , art. 2112902
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4.
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12 p, 6.1 MB |
A new source of representative secondary PET nanoplastics. Obtention, characterization, and hazard evaluation
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Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Rubio Lorente, Laura (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
López-Mesas, Montserrat (Universitat Autònoma de Barcelona. Departament de Química) ;
Fuentes-Cebrian, Victor (Universitat Autònoma de Barcelona. Departament de Química) ;
Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Micro and nanoplastics (MNPLs) are emergent environmental pollutants requiring urgent information on their potential risks to human health. One of the problems associated with the evaluation of their undesirable effects is the lack of representative samples, matching those resulting from the environmental degradation of plastic wastes. [...]
2022 - 10.1016/j.jhazmat.2022.129593
Journal of Hazardous Materials, Vol. 439 (October 2022) , art. 129593
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5.
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12 p, 1.1 MB |
Pharmacokinetics of PEGylated gold nanoparticles : in vitro-in vivo correlation
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Dubaj, Tibor (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics) ;
Kozics, Katarina (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ;
Sramkova, Monika (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ;
Manova, Alena (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ;
Kohl, Yvonne (Fraunhofer Institute for Biomedical Engineering) ;
Dusinska, Maria (Norwegian Institute for Air Research. Health Effects Laboratory) ;
Rundén-Pran, Elise (Norwegian Institute for Air Research. Health Effects Laboratory) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Nelson, Andrew (University of Leeds. School of Chemistry) ;
Gabelova, Alena (Biomedical Research Center SAS. Cancer Research Institute (Bratislava, Eslovàquia)) ;
Šimon, Peter (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics)
Data suitable for assembling a physiologically-based pharmacokinetic (PBPK) model for nanoparticles (NPs) remain relatively scarce. Therefore, there is a trend in extrapolating the results of in vitro and in silico studies to in vivo nanoparticle hazard and risk assessment. [...]
2022 - 10.3390/nano12030511
Nanomaterials, Vol. 12, issue 3 (Feb. 2022) , art. 511
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6.
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21 p, 2.2 MB |
Hepato(Geno)toxicity assessment of nanoparticles in a HepG2 liver spheroid model
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Elje, Elisabeth (Norwegian Institute for Air Research. Department for Environmental Chemistry) ;
Mariussen, Espen (Norwegian Institute for Air Research. Department for Environmental Chemistry) ;
Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Kohl, Yvonne (Fraunhofer Institute for Biomedical Engineering IBMT) ;
Dusinska, Maria (Norwegian Institute for Air Research. Department for Environmental Chemistry)) ;
Rundén-Pran, Elise (Norwegian Institute for Air Research. Department for Environmental Chemistry)
(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures better than 2D cultures. [...]
2020 - 10.3390/nano10030545
Nanomaterials, Vol. 10, issue 3 (March 2020) , art. E545
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7.
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15 p, 4.6 MB |
Microfluidic in vitro platform for (nano)safety and (nano)drug efficiency screening
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Kohl, Yvonne (Fraunhofer Institute for Biomedical Engineering) ;
Biehl, Margit (Fraunhofer Institute for Biomedical Engineering) ;
Spring, Sarah (Fraunhofer Institute for Biomedical Engineering) ;
Hesler, Michelle (Fraunhofer Institute for Biomedical Engineering) ;
Ogourtsov, Vladimir (University College Cork. Tyndall National Institute) ;
Todorovic, Miomir (University College Cork. Tyndall National Institute) ;
Owen, Joshua (University of Leeds. Institute of Thermofluids) ;
Elje, Elisabeth (University of Oslo. Department of Molecular Medicine) ;
Kopecka, Kristina (Slovak Academy of Sciences. Biomedical Research Center) ;
Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Šimon, Peter (Slovak University of Technology in Bratislava. Institute of Physical Chemistry and Chemical Physics) ;
Dubaj, Tibor (Institute of Physical Chemistry and Chemical Physicsof SUT) ;
Rundén-Pran, Elise (Norwegian Institute for Air Research. Department for Environmental Chemistry) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
William, Nicola (University of Leeds. School of Chemistry) ;
von Briesen, Hagen (Fraunhofer Institute for Biomedical Engineering) ;
Wagner, Sylvia (Fraunhofer Institute for Biomedical Engineering) ;
Kapur, Nikil (University of Leeds. Institute of Thermofluids) ;
Mariussen, Espen (Norwegian Institute for Air Research. Department for Environmental Chemistry) ;
Nelson, Andrew (University of Leeds. School of Chemistry) ;
Gabelova, Alena (Slovak Academy of Sciences. Biomedical Research Center) ;
Dusinska, Maria (Norwegian Institute for Air Research. Department for Environmental Chemistry) ;
Velten, Thomas (Fraunhofer Institute for Biomedical Engineering) ;
Knoll, Thorsten (Fraunhofer Institute for Biomedical Engineering)
Microfluidic technology is a valuable tool for realizing more in vitro models capturing cellular and organ level responses for rapid and animal-free risk assessment of new chemicals and drugs. Microfluidic cell-based devices allow high-throughput screening and flexible automation while lowering costs and reagent consumption due to their miniaturization. [...]
2021 - 10.1002/smll.202006012
Small, Vol. 17, issue 15 (April 2021) , art. 2006012
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8.
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14 p, 3.5 MB |
Assessment of iron oxide nanoparticle ecotoxicity on regeneration and homeostasis in the replacement model system Schmidtea mediterranea
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Tran, Thao A. (Fraunhofer Institute for Biomedical Engineering IBMT) ;
Hesler, Michelle (Fraunhofer Institute for Biomedical Engineering IBMT) ;
Moriones, Oscar Hernando (Institut Català de Nanociència i Nanotecnologia) ;
Jimeno Romero, Alba (Universidad del País Vasco) ;
Fischer, Benjamin (Fraunhofer Institute for Biomedical Engineering IBMT) ;
Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Wagner, Sylvia (Fraunhofer Institute for Biomedical Engineering IBMT) ;
Kohl, Yvonne L. (Fraunhofer Institute for Biomedical Engineering IBMT) ;
Gentile, Luca (Fraunhofer Institute for Biomedical Engineering IBMT)
Iron oxide nanoparticles (IONs) are used in a number of applications, from food to cosmetics, from medical applications to magnetic storage. In spite of the 550 tons produced each year in Europe alone, no effective dose limit recommendations are established and the overall risks connected to IONs are still debated. [...]
2019 - 10.14573/altex.1902061
ALTEX, Vol. 36, Núm. 4 (October 2019) , p. 583-596
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