Results overview: Found 19 records in 0.02 seconds.
Articles, 17 records found
Research literature, 2 records found
Articles 17 records found  1 - 10next  jump to record:
1.
9 p, 3.7 MB The Genome-wide Methylation Profile of CD4+ T Cells From Individuals With Human Immunodeficiency Virus (HIV) Identifies Distinct Patterns Associated With Disease Progression / Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Lopez, Miguel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gómez Moruno, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Passaes, Caroline (Institut Pasteur) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Saez-Cirion, Asier (Institut Pasteur) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Berdasco, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
BACKGROUND: Human genetic variation-mostly in the human leukocyte antigen (HLA) and C-C chemokine receptor type 5 (CCR5) regions-explains 25% of the variability in progression of human immunodeficiency virus (HIV) infection. [...]
2021 - 10.1093/cid/ciaa1047
Clinical Infectious Diseases, Vol. 72 Núm. 9 (april 2021) , p. e256-e264  
2.
25 p, 3.6 MB Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control / Oriol-Tordera, Bruna (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Berdasco, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Llano, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Duran-Castells, Clara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ganoza, C. (Alberto Hurtado School of Medicine. Universidad Peruana Cayetano Heredia) ; Sanchez, J. (Centro de Investigaciones Tecnológicas. Biomédicas y Medioambientales. CITBM) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Calle, M.L. (Universitat de Vic - Universitat Central de Catalunya) ; Sánchez, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
GWAS, immune analyses and biomarker screenings have identified host factors associated with in vivo HIV-1 control. However, there is a gap in the knowledge about the mechanisms that regulate the expression of such host factors. [...]
2020 - 10.1371/JOURNAL.PPAT.1008678
PLoS pathogens, Vol. 16 Núm. 8 (june 2020) , p. e1008678  
3.
10 p, 586.9 KB Novel Approaches Towards a Functional Cure of HIV/AIDS / Bailón, Lucía (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Berman, Lance (AELIX Therapeutics) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Therapeutic approaches towards a functional cure or eradication of HIV have gained renewed momentum upon encouraging data emerging from studies in SIV monkey models and recent results from human clinical studies. [...]
2020 - 10.1007/s40265-020-01322-y
Drugs, Vol. 80 (may 2020) , p. 859-868  
4.
16 p, 2.9 MB Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study) / Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Manzardo, Christian (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Sánchez-Bernabeu, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Coll, Pep (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rosás-Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cobarsi, Patricia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Escrig, Roser (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz, Irene (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rovira, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Meulbroek, Michael (Projecte del Noms, BCN Checkpoint, Barcelona, Spain) ; Crook, Alison (The Jenner Institute, University of Oxford, Oxford, UK) ; Borthwick, Nicola (The Jenner Institute, University of Oxford, Oxford, UK) ; Wee, Edmund G. (The Jenner Institute, University of Oxford, Oxford, UK) ; Yang, Hongbing (Nuffield Department of Medicine and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK) ; Miró, Jose M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Dorrell, Lucy (Nuffield Department of Medicine and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hanke, Tomáš (International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan) ; Universitat Autònoma de Barcelona
Strong and broad antiviral T-cell responses targeting vulnerable sites of HIV-1 will likely be a critical component for any effective cure strategy. BCN01 trial was a phase I, open-label, non-randomized, multicenter study in HIV-1-positive individuals diagnosed and treated during early HIV-1 infection to evaluate two vaccination regimen arms, which differed in the time (8 versus 24 week) between the ChAdV63. [...]
2019 - 10.1016/j.eclinm.2019.05.009
EClinicalMedicine, Vol. 11 (june 2019) , p. 65-80  
5.
1 p, 240.0 KB Corrigendum to 'Therapeutic vaccination refocuses T-cell responses towards conserved regions of HIV-1 in early treated individuals (BCN 01 study)' EClinicalMedicine 11 (2019) 65-80 / Mothe, Beatriz (Universitat de Vic - Universitat Central de Catalunya) ; Manzardo, Christian (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Sanchez-Bernabeu, Alvaro (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Coll, Pep (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rosás-Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cobarsi, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Escrig, Roser (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruiz, Irene (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rovira, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Meulbroek, Michael (Projecte del Noms, BCN Checkpoint, Barcelona, Spain) ; Crook, Alison (The Jenner Institute, University of Oxford, Oxford, UK) ; Borthwick, Nicola (The Jenner Institute, University of Oxford, Oxford, UK) ; Wee, Edmund G. (The Jenner Institute, University of Oxford, Oxford, UK) ; Yang, Hongbing (Nuffield Department of Medicine and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK) ; Miró, Jose M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Dorrell, Lucy (Nuffield Department of Medicine and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hanke, Tomáš (International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan) ; Universitat Autònoma de Barcelona
2020 - 10.1016/j.eclinm.2019.100250
EClinicalMedicine, Vol. 18 (january 2020)  
6.
15 p, 3.9 MB Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection / Guillén Montalbán, Yolanda. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Zevin, Alexander (University of Washington) ; Rocafort, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Parera, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez, C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Arumí, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Estany Quera, Carla (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Coll, Josep (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bravo, I. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Herrero, C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Saz, J. (BCN Checkpoint) ; Sirera, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Torrella Domingo, Adriana (Hospital Universitari Vall d'Hebron) ; Navarro, Jordi (Hospital Universitari Vall d'Hebron) ; Crespo, M. (Infectious Diseases Unit. Internal Medicine Department. Complexo Hospitalario Universitario. Vigo. IIS Galicia Sur) ; Negredo Puigmal, Eugènia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Brander, Christian. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Calle, M.L. (Universitat de Vic - Universitat Central de Catalunya) ; Klatt, N.R. (University of Washington) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Human immunodeficiency virus (HIV)-1 infection causes severe gut and systemic immune damage, but its effects on the gut microbiome remain unclear. Previous shotgun metagenomic studies in HIV-negative subjects linked low-microbial gene counts (LGC) to gut dysbiosis in diseases featuring intestinal inflammation. [...]
2019 - 10.1038/s41385-018-0083-7
Mucosal Immunology, Vol. 12 Núm. 1 (january 2019) , p. 232-246  
7.
0 p, 5.4 MB Antigen production after latency reversal and expression of inhibitory receptors in CD8+ T cells limit the killing of HIV-1 reactivated cells / Ruiz, A. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanch-Lombarte, Oscar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Jimenez-Moyano, Esther (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Peña, R. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Genescà Ferrer, Meritxell. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Goulder, P. (Department of Paediatrics. University of Oxford) ; Barnard, R. (Department of Infectious Disease. Merck and Co. Inc.) ; Howell, B. (Department of Infectious Disease. Merck and Co. Inc.) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
The so-called shock and kill therapies aim to combine HIV-1 reactivation by latency-reversing agents (LRA) with immune clearance to purge the HIV-1 reservoir. The clinical use of LRA has demonstrated detectable perturbations in the HIV-1 reservoir without measurable reductions to date. [...]
2019 - 10.3389/fimmu.2018.03162
Frontiers in immunology, Vol. 10 Núm. JAN (2019) , p. 3162  
8.
15 p, 676.0 KB Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers / Rosás Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Llano, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz-Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fernández, Marco A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cobarsi, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Crespo, Manel (Complexo Hospitalario Universitario de Vigo) ; Dorrell, Lucy (Nuffield Department of Medicine, University of Oxford) ; Del Romero, Jorge (Centro Sanitario Sandoval, Madrid) ; Alcami, Jose (Instituto de Salud Carlos III) ; Paredes, Roger (Universitat Autònoma de Barcelona. Departament de Medicina) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
A few individuals can control HIV infection without the need for antiretroviral treatment and are referred to as HIV controllers. We have studied HIV controllers who suddenly lose this ability and present with high in vivo viral replication and decays in their CD4 + T-cell counts to identify potential immune and virological factors that were responsible for initial virus control. [...]
2019 - 10.1128/JVI.01436-18
Journal of Virology, Vol. 93 (february 2019)  
9.
14 p, 2.0 MB Differential Immunodominance Hierarchy of CD8 + T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection / Adland, Emily ; Hill, Matilda ; Lavandier, Nora ; Csala, Anna ; Edwards, Anne ; Chen, Fabian ; Radkowski, Marek ; Kowalska, Justyna D. ; Paraskevis, Dimitrios ; Hatzakis, Angelos ; Valenzuela-Ponce, Humberto ; Pfafferott, Katja ; Williams, Ian ; Pellegrino, Pierre ; Borrow, Persephone ; Mori, Masahiko ; Rockstroh, Jürgen ; Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Tudor-Williams, Gareth ; Frater, John ; Stryhn, Anette ; Buus, Soren ; Teran, Gustavo Reyes ; Mallal, Simon ; John, Mina ; Buchbinder, Susan ; Kirk, Gregory ; Martin, Jeffrey ; Michael, Nelson ; Fellay, Jacques ; Deeks, Steve ; Walker, Bruce ; Avila-Rios, Santiago ; Cole, David ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrington, Mary ; Goulder, Philip ; Universitat Autònoma de Barcelona
The well-characterized association between HLA-B*27:05 and protection against HIV disease progression has been linked to immunodominant HLA-B*27:05-restricted CD8 + T-cell responses toward the conserved Gag KK10 (residues 263 to 272) and polymerase (Pol) KY9 (residues 901 to 909) epitopes. [...]
2018 - 10.1128/JVI.01685-17
Journal of Virology, Vol. 92 (january 2018)  
10.
13 p, 2.5 MB Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control / Ruiz-Riol, M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Berdnik, D. ; Llano, A. (Institut Germans Trias i Pujol) ; Mothe, Beatriz. (Institut Germans Trias i Pujol) ; Gálvez, Cristina (Institut Germans Trias i Pujol) ; Pérez-Álvarez, Susana (Institut Germans Trias i Pujol) ; Oriol-Tordera, B. (Institut Germans Trias i Pujol) ; Olvera, A. (Institut Germans Trias i Pujol) ; Silva-Arrieta, S. (Institut Germans Trias i Pujol) ; Meulbroek, M. (Institut Germans Trias i Pujol) ; Pujol, Ferran (Projecte dels NOMS-HISPANOSIDA) ; Coll, Josep (Institut Germans Trias i Pujol) ; Martinez-Picado, J. (Institut Germans Trias i Pujol) ; Ganoza, C. ; Sanchez, J. ; Gómez, G. ; Wyss-Coray, T. ; Brander, Christian. (Institut Germans Trias i Pujol)
Intact and broad immune cell effector functions and specific individual cytokines have been linked to HIV disease outcome, but their relative contribution to HIV control remains unclear. We asked whether the proteome of secreted cytokines and signaling factors in peripheral blood can be used to discover specific pathways critical for host viral control. [...]
2017 - 10.1128/JVI.00441-17
Journal of Virology, Vol. 91 (july 2017)  

Articles : 17 records found   1 - 10next  jump to record:
Research literature 2 records found  
1.
221 p, 7.9 MB Challenges and prospects for an immune-driven functional cure of HIV infection / Rosás Umbert, Míriam ; Brander, Christian, dir. ; Mothe Pujadas, Beatriz, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
El virus de la immunodeficiència humana (VIH), causant de la síndrome de la immunodeficiència adquirida (SIDA), és una de les majors pandèmies del nostre temps. Al 2018, van haver-hi 1,7 milions noves infeccions i es calcula que actualment, més de 37,9 milions de persones viuen amb el VIH-1 a tot el món. [...]
Human Immunodeficiency Virus (HIV) infection causing the Acquired Immune Deficiency Syndrome (AIDS) is one of the major pandemics of our time. In 2018, 1. 7 million of new infections occurred and over 37. [...]

2019  
2.
305 p, 8.1 MB Rational design and testing of novel HIV T cell immunogens / Mothe, Beatriz ; Brander, Christian, dir. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Clotet, Bonaventura, dir. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Universitat Autònoma de Barcelona. Departament de Medicina
Aquesta tesi doctoral té com a objectiu caracteritzar millor les respostes VIH específiques de les cèl·lules T (CTL), identificar les dianes virals implicades en el control del virus i desenvolupar com aquesta informació s'ha incorporat en el disseny d'un inmunogen per a una futura vacuna contra el VIH. [...]
This doctoral thesis aims to better characterize HIV specific T cell responses, define the viral targets most implicated in mediating viral control and discuss how this information has been incorporated into a rational immunogen design for a future HIV vaccine. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2012  

See also: similar author names
1 Mothe, B.
4 Mothe, Beatriz.
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