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10 p, 507.5 KB Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice / Hervera Abad, Arnau (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Leánez, Sergi (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Negrete, Roger (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Motterlini, Roberto (Université Paris-Est) ; Pol, Olga (Universitat Autònoma de Barcelona. Institut de Neurociències)
Background: Carbon monoxide (CO) synthesized by heme oxygenase 1 (HO-1) exerts antinociceptive effects during inflammation but its role during neuropathic pain remains unknown. Our objective is to investigate the exact contribution of CO derived from HO-1 in the modulation of neuropathic pain and the mechanisms implicated. [...]
2012 - 10.1371/journal.pone.0043693
PloS one, Vol. 7, Issue 8 (August 2012) , p. e43693  
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