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6 p, 5.8 MB Centrality in the host–pathogen interactome is associated with pathogen fitness during infection / Crua Asensio, Núria (Hospital Universitari Vall d'Hebron) ; Muñoz Giner, Elisabet (Hospital Universitari Vall d'Hebron) ; Sánchez de Groot, Natalia (Universitat Pompeu Fabra) ; Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
To perform their functions proteins must interact with each other, but how these interactions influence bacterial infection remains elusive. Here we demonstrate that connectivity in the host–pathogen interactome is directly related to pathogen fitness during infection. [...]
2017 - 10.1038/ncomms14092
Nature Communications, Vol. 8 (January 2017) , art. 14092  

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