Resultats globals: 3 registres trobats en 0.02 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
2 p, 188.6 KB Synthesis, in vitro profiling, and in vivo efficacy studies of a new family of multitarget antiAlzheimer compounds / Pérez-Areales, Francisco Javier (University of Barcelona) ; Garrido, María (Instituto de Química Avanzada de) ; Catalunya (IQAC-CSIC) ; Aso, Ester (University of Barcelona) ; Bartolini, Manuela (Department of Pharmacy and Biotechnology. Alma Mater Studiorum University of Bologna) ; De Simone, Angela (University of Bologna. Department for Life Quality Studies) ; Espargaró Colomé, Alba (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ginex, Tiziana (University of Barcelona) ; Sabate, Raimon (University of Barcelona) ; Pérez, Belén (Autonomous University of Barcelona. Therapeutics and Toxicology) ; Andrisano, Vincenza (University of Bologna. Department for Life Quality Studies) ; Luque, Francisco Javier (University of Barcelona) ; Ferrer, Isidro (Universitat de Barcelona. Unitat de Neuropatologia Experimental) ; Ciruela, Francisco (University of Barcelona) ; Messeguer, Àngel (Instituto de Química Avanzada de) ; Catalunya (IQAC-CSIC) ; Muñoz Torrero, Diego (Universitat de Barcelona. Laboratori de Química Farmacèutica)
Simultaneous modulation of several targets or athological events with a key pathogenic role is a promising strategy to tackle thus far difficult-to-cure or incurable multifactorial diseases, such as Alzheimer's disease (AD). [...]
2019 - 10.3390/proceedings2019022071
Proceedings, Vol. 22 (2019) , p. 1-2  
2.
8 p, 812.8 KB Tetrasubstituted imidazolium salts as potent antiparasitic agents against African and American trypanosomiases / Ghashghaei, Ouldouz (Universitat de Barcelona. Laboratori de Química Orgànica) ; Kielland, Nicola (Universitat de Barcelona. Laboratori de Química Orgànica) ; Revés, Marc (Universitat de Barcelona. Laboratori de Química Orgànica) ; Taylor, Martin C. (Department of Pathogen Molecular Biology. London School of Hygiene and Tropical Medicine) ; Kelly, John M. (Department of Pathogen Molecular Biology. London School of Hygiene and Tropical Medicine) ; Pietro, Ornella Di (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Muñoz Torrero, Diego (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Pérez, Belén. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lavilla, Rodolfo (Universitat de Barcelona. Laboratori de Química Orgànica)
Imidazolium salts are privileged compounds in organic chemistry, and have valuable biological properties. Recent studies show that symmetric imidazolium salts with bulky moieties can display antiparasitic activity against T. [...]
2018 - 10.3390/molecules23010177
Molecules, Vol. 23 Núm. 1 (2018) , p. 177  
3.
19 p, 3.9 MB Increasing polarity in tacrine and huprine derivatives : Potent anticholinesterase agents for the treatment of myasthenia gravis / Galdeano, Carles (Universitat de Barcelona. Laboratori de Química Farmaceutica) ; Coquelle, Nicolas (Large-Scale Structures Group. Institut Laue-Langevin) ; Cieslikiewicz-Bouet, Monika (Laboratory COBRA (UMR 6014). Normandie Université. UNIROUEN. Institut National des Sciences Appliquées (INSA) Rouen. CNRS) ; Bartolini, Manuela (Department of Pharmacy and Biotechnology. Alma Mater Studiorum University of Bologna) ; Pérez, Belen (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Clos, Victòria (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Silman, Israel (Department of Neurobiology. Weizmann Institute of Science) ; Jean, Ludovic (Laboratory COBRA (UMR 6014). Normandie Université. UNIROUEN. Institut National des Sciences Appliquées (INSA) Rouen. CNRS) ; Colletier, Jacques Phillippe (Institut de Biologie Structurale. Université Grenoble Alpes. Centre National de la Recherche Scientifique (CNRS). Commissariat à l'Énergie Atomique (CEA) (UMR 5075)) ; Renard, Pierre Yves (Laboratory COBRA (UMR 6014). Normandie Université. UNIROUEN. Institut National des Sciences Appliquées (INSA) Rouen. CNRS) ; Muñoz Torrero, Diego (Universitat de Barcelona. Laboratori de Química Farmaceutica)
Symptomatic treatment of myasthenia gravis is based on the use of peripherally-acting acetylcholinesterase (AChE) inhibitors that, in some cases, must be discontinued due to the occurrence of a number of side-effects. [...]
2018 - 10.3390/molecules23030634
Molecules, Vol. 23 Núm. 3 (2018) , p. 634  

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