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10 p, 328.8 KB |
Cannabinoids : from pot to lab
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Papaseit, Esther (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Pérez-Mañá, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Pérez-Acevedo, Ana Pilar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hladun, Olga (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Torres-Moreno, M. Carmen (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Torrens, Marta (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Farré Albaladejo, Magí (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Cannabis is becoming increasingly present in our society. In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and the medical (pharmaceutical cannabinoids and medical cannabis) has been crossed. [...]
2018 -  10.7150/ijms.27087
International Journal of Medical Sciences, Vol. 15 (august 2018) , p. 1286-1295
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2.
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9 p, 883.8 KB |
Hepatitis C infection substantially reduces survival of alcohol-dependent patients
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Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Jarrin, Inmaculada (Instituto de Salud Carlos III) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bolao, Ferran (Hospital Universitari de Bellvitge) ;
Tor, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muñoz, Alvaro (Johns Hopkins University) ;
Universitat Autònoma de Barcelona
Heavy alcohol use is associated with life-threatening complications including progressive liver disease. We aimed to analyze the impact of hepatitis C virus (HCV) infection on survival and liver-related death in alcohol-dependent patients. [...]
2018 - 10.2147/CLEP.S162308
Clinical Epidemiology, Vol. 10 (august 2018) , p. 897-905
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3.
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2 p, 474.1 KB |
La crisi dels opioides
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Fuster, Daniel (Hospital Universitari Germans Trias i Pujol. Servei de Medicina Interna-Unitat d'Addiccions) ;
Muga, Roberto (Hospital Universitari Germans Trias i Pujol. Servei de Medicina Interna-Unitat d'Addiccions)
En una editorial recentment publicada a Medicina Clínica els Drs. Daniel Fuster i Robert Muga, del Servei de Medicina Interna l'Hospital Universitari Germans Trias i Pujol discuteixen els orígens de l'emergència de salut pública als Estats Units relacionada amb l'augment de la prevalença del trastorn per ús d' opioides i l'augment alarmant de morts per sobredosi, que ha arribat a la xifra de 75000 a l'any. [...]
2019
UAB divulga, Abril 2019, p. 1-2
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4.
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18 p, 347.2 KB |
Comparing dynamic monitoring strategies based on evolving CD4 cell counts in virologically suppressed HIV-positive individuals on cART : a prospective observational study in high-income countries
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Caniglia, Ellen, C. (Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.) ;
Cain, Lauren E. ;
Sabin, Caroline A. ;
Robins, James M. ;
Logan, Roger ;
Abgrall, Sophie ;
Mugavero, Michael J. ;
Hernández-Díaz, Sonia ;
Meyer, Laurence ;
Seng, Remonie ;
Drozd, Daniel R. ;
Seage, George R. ;
Dabis, Francois ;
Fabrice, Bonnet ;
Richard, D Moore ;
Reiss, Peter ;
van Sighem, Ard ;
Mathews, William C. ;
Del Amo, Julia ;
Moreno, Santiago ;
Deeks, Steven G. ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Boswell, Stephen L. ;
Ferrer, Elena ;
Eron, Joseph J. ;
Napravnik, Sonia ;
Jose, Sophie ;
Phillips, Andrew ;
Justice, Amy C ;
Tate, Janet P. ;
Gill, John ;
Pacheco, Antonio ;
Veloso, Valdilea G ;
Bucher, Heiner C ;
Egger, Matthias ;
Furrer, Hansjakob ;
Kholoud, Porter ;
Touloumi, Giota ;
Crane, Heidi ;
Miró, Jose M. ;
Sterne, Jonathan A. ;
Dominique, Costagliola ;
Saag, Michael ;
Hernán, Miguel A.
Clinical guidelines vary with respect to the optimal monitoring frequency of HIV-positive individuals. We compared dynamic monitoring strategies based on evolving CD4 cell counts in virologically suppressed HIV-positive individuals. [...]
2017 - 10.1016/S2352-3018(17)30043-7
The lancet. HIV, Vol. 4 (april 2017) , p. e251-e259
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5.
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8 p, 283.7 KB |
When to Monitor CD4 Cell Count and HIV RNA to Reduce Mortality and AIDS-Defining Illness in Virologically Suppressed HIV-Positive Persons on Antiretroviral Therapy in High-Income Countries : A Prospective Observational Study
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Caniglia, Ellen C. (Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA) ;
Sabin, Caroline (University College London, London, United Kingdom) ;
Robins, James M. (Department of Biostatistics, Harvard T.H. Chan School of Public Health) ;
Logan, Roger (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Cain, Lauren E. (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Abgrall, Sophie (Assistance Publique-Hopitaux de Paris (AP-HP), Hopital Antoine Béclère, Service de Médecine Interne) ;
Mugavero, Michael J. (University of Alabama at Birmingham) ;
Hernandez-Diaz, Sonia (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Meyer, Laurence (Université Paris Sud, INSERM CESP U1018, and AP-HP, Hopital de Bicêtre, Service de Santé Publique) ;
Seng, Remonie (Université Paris Sud, INSERM CESP U1018, and AP-HP, Hopital de Bicêtre, Service de Santé Publique) ;
Drozd, Daniel R. (Division of Allergy and Infectious Diseases, School of Medicine, University of Washington) ;
Seage, George R. (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Bonnet, Fabrice (Bordeaux University, ISPED, INSERM U897 CHU de Bordeaux) ;
Dabis, Francois (INSERM U897, Centre Inserm Epidémiologie et Biostatistique, Université de Bordeaux, and Department of Internal Medicine, Bordeaux University Hospital) ;
Moore, Richard R. (School of Medicine, Johns Hopkins University, Baltimore, MD) ;
Reiss, Peter (Stichting HIV Monitoring, Amsterdam, Netherlands; Academic Medical Center, Department of Global Health and Division of Infectious Diseases, University of Amsterdam, and Amsterdam Institute for Global Health and Development) ;
van Sighem, Ard (Stichting HIV Monitoring, Amsterdam, Netherlands) ;
Mathews, William C. (Internal Medicine, Johns Hopkins University) ;
del Amo, Julia (National Centre of Epidemiology, Instituto de Salud Carlos III, Madrid, Spain; Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP)) ;
Moreno, Santiago (Ramón y Cajal Hospital, IRYCIS, University of Alcalá de Henares) ;
Deeks, Steven G. (Positive Health Program, San Francisco General Hospital) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei de Medicina Interna) ;
Boswell, Stephen L. (Fenway Health) ;
Ferrer, Elena (Hospital Universitari de Bellvitge-Bellvitge Institute for Biomedical Research) ;
Eron, Joseph J. (Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill) ;
Napravnik, Sonia (Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill) ;
Jose, Sophie (University College London) ;
Phillips, Andrew (University College London, London, United Kingdom) ;
Olson, Ashley (Medical Research Council Clinical Trials Unit, University College London) ;
Justice, Amy C. (VA Connecticut Healthcare System) ;
Tate, Janet P. (VA Connecticut Healthcare System) ;
Bucher, Heiner C. (Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel) ;
Egger, Matthias (University of Bern, Institute for Social and Preventive Medicine, Bern, Switzerland) ;
Touloumi, Giota (Department of Hygiene, Epidemiology and Medical Statistics, Athens University Medical School) ;
Sterne, Jonathan A. (School of Social and Community Medicine, University of Bristol) ;
Costagliola, Dominique (Sorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136)) ;
Saag, Michael (Department of Medicine, University of Alabama at Birmingham) ;
Hernán, Miguel A. (Department of Medicine, University of Alabama at Birmingham) ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is Available in the Text. To illustrate an approach to compare CD4 cell count and HIV-RNA monitoring strategies in HIV-positive individuals on antiretroviral therapy (ART). [...]
2016 - 10.1097/QAI.0000000000000956
Journal of acquired immune deficiency syndromes (1999), Vol. 72 (may 2016) , p. 214-221
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7 p, 278.1 KB |
Sex-specific disease outcomes of HIV-positive and HIV-negative drug users admitted to an opioid substitution therapy program in Spain : a cohort study
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Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rivas, Inmaculada (Centre d'Atenció i Seguiment de Drogodependencies Delta) ;
Faure, Eva (Centre d'Atenció i Seguiment de Drogodependencies Delta) ;
Fuster, Daniel (Boston Medical Center, Boston University School of Medicine) ;
Zuluaga, Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rubio, Manuela (Centre d'Atenció i Seguiment de Drogodependencies Delta) ;
Muñoz, Trinidad (Centre d'Atenció i Seguiment de Drogodependencies Delta) ;
Torrens, Marta (Universitat Autònoma de Barcelona) ;
Tor, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Opioid substitution therapy has improved the survival of heroin users with and without HIV infection. We aimed to analyze sex differences in mortality rates and predictors of death among those admitted to a methadone treatment program (MTP). [...]
2014 - 10.1186/1471-2334-14-504
BMC Infectious diseases, Vol. 14 (september 2014)
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6 p, 262.2 KB |
Long-Term Mortality of Patients with an Alcohol-Related Wernicke-Korsakoff Syndrome
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Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zuluaga, Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rivas, Inmaculada (Centre Delta) ;
Tor, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Marcos, Miguel (Hospital Universitario de Salamanca) ;
Chamorro, Antonio J. (Hospital Universitario de Salamanca) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Aims: To characterize a series of contemporary patients with alcohol-related Wernicke's encephalopathy (WE) or Korsakoff's syndrome (KS) and to update the current prognosis of disease. Methods: Retrospective and prospective study of patients diagnosed with an alcohol-related WE or KS between 2002 and 2011 in a tertiary hospital. [...]
2017 - 10.1093/alcalc/agx013
Alcohol and alcoholism, 2017
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12 p, 7.8 MB |
Alcohol Consumption during Pregnancy : Analysis of Two Direct Metabolites of Ethanol in Meconium
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Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Robert, Neus (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández Pérez, José María (Institut Germans Trias i Pujol) ;
Zuluaga, Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Farré Albaladejo, Magí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Coroleu, Wifredo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Serra Landete, Montserrat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tor Aguilera, J. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Alcohol consumption in young women is a widespread habit that may continue during pregnancy and induce alterations in the fetus. We aimed to characterize prevalence of alcohol consumption in parturient women and to assess fetal ethanol exposure in their newborns by analyzing two direct metabolites of ethanol in meconium. [...]
2016 - 10.3390/ijms17030417
International journal of molecular sciences, Vol. 17 Núm. 3 (March 2016)
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7 p, 178.2 KB |
Markers of inflammation and mortality in a cohort of patients with alcohol dependence
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Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bolao, Ferran (Hospital Universitari de Bellvitge) ;
Zuluaga, Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rivas, Inmaculada (Servei d'Atenció a Persones amb Problemes de Drogodependència (Badalona, Barcelona)) ;
Tor Aguilera, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Abstract. Inflammation and intestinal permeability are believed to be paramount features in the development of alcohol-related liver damage. We aimed to assess the impact of 3 surrogate markers of inflammation (anemia, fibrinogen, and ferritin levels) on mid-term mortality of patients with alcohol dependence. [...]
2015 - 10.1097/MD.0000000000000607
Medicine, Vol. 94(10) (March 2015)
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