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18 p, 347.2 KB |
Comparing dynamic monitoring strategies based on evolving CD4 cell counts in virologically suppressed HIV-positive individuals on cART : a prospective observational study in high-income countries
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Caniglia, Ellen, C. (Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.) ;
Cain, Lauren E. ;
Sabin, Caroline A. ;
Robins, James M. ;
Logan, Roger ;
Abgrall, Sophie ;
Mugavero, Michael J. ;
Hernández-Díaz, Sonia ;
Meyer, Laurence ;
Seng, Remonie ;
Drozd, Daniel R. ;
Seage, George R. ;
Dabis, Francois ;
Fabrice, Bonnet ;
Richard, D Moore ;
Reiss, Peter ;
van Sighem, Ard ;
Mathews, William C. ;
Del Amo, Julia ;
Moreno, Santiago ;
Deeks, Steven G. ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Boswell, Stephen L. ;
Ferrer, Elena ;
Eron, Joseph J. ;
Napravnik, Sonia ;
Jose, Sophie ;
Phillips, Andrew ;
Justice, Amy C ;
Tate, Janet P. ;
Gill, John ;
Pacheco, Antonio ;
Veloso, Valdilea G ;
Bucher, Heiner C ;
Egger, Matthias ;
Furrer, Hansjakob ;
Kholoud, Porter ;
Touloumi, Giota ;
Crane, Heidi ;
Miró, Jose M. ;
Sterne, Jonathan A. ;
Dominique, Costagliola ;
Saag, Michael ;
Hernán, Miguel A. ;
Universitat Autònoma de Barcelona
Clinical guidelines vary with respect to the optimal monitoring frequency of HIV-positive individuals. We compared dynamic monitoring strategies based on evolving CD4 cell counts in virologically suppressed HIV-positive individuals. [...]
2017 -  10.1016/S2352-3018(17)30043-7
The lancet. HIV, Vol. 4 (april 2017) , p. e251-e259
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8 p, 283.7 KB |
When to Monitor CD4 Cell Count and HIV RNA to Reduce Mortality and AIDS-Defining Illness in Virologically Suppressed HIV-Positive Persons on Antiretroviral Therapy in High-Income Countries : A Prospective Observational Study
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Caniglia, Ellen C. (Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA) ;
Sabin, Caroline (University College London, London, United Kingdom) ;
Robins, James M. (Department of Biostatistics, Harvard T.H. Chan School of Public Health) ;
Logan, Roger (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Cain, Lauren E. (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Abgrall, Sophie (Assistance Publique-Hopitaux de Paris (AP-HP), Hopital Antoine Béclère, Service de Médecine Interne) ;
Mugavero, Michael J. (University of Alabama at Birmingham) ;
Hernandez-Diaz, Sonia (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Meyer, Laurence (Université Paris Sud, INSERM CESP U1018, and AP-HP, Hopital de Bicêtre, Service de Santé Publique) ;
Seng, Remonie (Université Paris Sud, INSERM CESP U1018, and AP-HP, Hopital de Bicêtre, Service de Santé Publique) ;
Drozd, Daniel R. (Division of Allergy and Infectious Diseases, School of Medicine, University of Washington) ;
Seage, George R. (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Bonnet, Fabrice (Bordeaux University, ISPED, INSERM U897 CHU de Bordeaux) ;
Dabis, Francois (INSERM U897, Centre Inserm Epidémiologie et Biostatistique, Université de Bordeaux, and Department of Internal Medicine, Bordeaux University Hospital) ;
Moore, Richard R. (School of Medicine, Johns Hopkins University, Baltimore, MD) ;
Reiss, Peter (Stichting HIV Monitoring, Amsterdam, Netherlands; Academic Medical Center, Department of Global Health and Division of Infectious Diseases, University of Amsterdam, and Amsterdam Institute for Global Health and Development) ;
van Sighem, Ard (Stichting HIV Monitoring, Amsterdam, Netherlands) ;
Mathews, William C. (Internal Medicine, Johns Hopkins University) ;
del Amo, Julia (National Centre of Epidemiology, Instituto de Salud Carlos III, Madrid, Spain; Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP)) ;
Moreno, Santiago (Ramón y Cajal Hospital, IRYCIS, University of Alcalá de Henares) ;
Deeks, Steven G. (Positive Health Program, San Francisco General Hospital) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei de Medicina Interna) ;
Boswell, Stephen L. (Fenway Health) ;
Ferrer, Elena (Hospital Universitari de Bellvitge-Bellvitge Institute for Biomedical Research) ;
Eron, Joseph J. (Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill) ;
Napravnik, Sonia (Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill) ;
Jose, Sophie (University College London) ;
Phillips, Andrew (University College London, London, United Kingdom) ;
Olson, Ashley (Medical Research Council Clinical Trials Unit, University College London) ;
Justice, Amy C. (VA Connecticut Healthcare System) ;
Tate, Janet P. (VA Connecticut Healthcare System) ;
Bucher, Heiner C. (Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel) ;
Egger, Matthias (University of Bern, Institute for Social and Preventive Medicine, Bern, Switzerland) ;
Touloumi, Giota (Department of Hygiene, Epidemiology and Medical Statistics, Athens University Medical School) ;
Sterne, Jonathan A. (School of Social and Community Medicine, University of Bristol) ;
Costagliola, Dominique (Sorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136)) ;
Saag, Michael (Department of Medicine, University of Alabama at Birmingham) ;
Hernán, Miguel A. (Department of Medicine, University of Alabama at Birmingham) ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is Available in the Text. To illustrate an approach to compare CD4 cell count and HIV-RNA monitoring strategies in HIV-positive individuals on antiretroviral therapy (ART). [...]
2016 - 10.1097/QAI.0000000000000956
Journal of acquired immune deficiency syndromes (1999), Vol. 72 (may 2016) , p. 214-221
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